The gut-brain connection is essential in the body. If an individual has a leaky gut that is causing inflammation, it can send the signal to the brain and it can create problems like neurotransmitter dysfunction to systems that just don�t connect. The leaky gut can lead to brain dysfunction or brain dysfunction can lead to leaky gut. Sometimes an autoimmunity disease in the stomach can lead to a disruption in the mind. Then, brain disruption can also lead to inflammation in the gut. It�s a never-ending loop that the brain and gut can go on forever. Studies have stated that gut microbiota appears to influence the development of emotional behaviors like stress, pain modulation systems, and brain neurotransmitter systems.
The Brain System to the Gut System
The brain is the main control room that controls the body�s system and how the body should behave. The human brain also contains neuron cells that are found in the central nervous system. With the gut-brain connection, two critical systems help send the signal to the brain and the gut; these are known as the vagus nerve and the neurotransmitters.
The Vagus Nerve
There are approximately 100 billion neurons in the brain, while the gut contains about 500 million neurons, which is connected to the brain through the nerves in the nervous system. The vagus nerve is one of the most significant nerves that send signals back and forth to the brain and the gut. When the body is stressed, the stress signal inhibits the vagus nerve, and it can cause problems to the gut-brain connection. Animal studies have shown that any stress that is in the animal�s body can cause gastrointestinal issues and PTSD. While another study stated that individuals that have IBS (irritable bowel syndrome) have a reduced function of the vagus nerve.
There are ways to reduce the stress hormone so that the vagus nerve can function properly and send the right signals to the gut and the brain. Probiotic foods can help lower the amount of stress hormone in the bloodstream. When that happens, the body can start healing naturally when the stress is reduced; however, if the vagus nerve is damaged, then the probiotic has no effect.
Neurotransmitters
Neurotransmitters are produced chemically in the brain by controlling feelings and emotions in the body. Since the brain and gut are connected to neurotransmitters, the neurotransmitters can create these compounds that help contribute to the body. In the brain, the neurotransmitter can produce serotonin to make the person feel happy and help control their body�s biological clock.
In the gut, there are trillions of microbes that live there, and interestingly researchers stated that serotonin is mainly being produced by the gut system. Another neurotransmitter that is provided in the gut is called GABA (gamma-aminobutyric acid), which helps control the feeling of fear and anxiety. When the brain feels overly anxious or has been through a traumatic experience that has caused them to be fearful, it can cause them to be hypersensitive and can cause a chemical imbalance to the gut, causing inflammation or leaky gut if it is severe.
The Gut System to the Brain System
The gut microbes can produce neurotransmitters to send to the brain, protect the intestinal barrier and the tight junction integrity, regulate the mucosal immune system, and modulates the enteric sensory afferents. The gut microbe produces a lot of SCFA (short-chain fatty acids) that form a barrier between the brain and blood flow called the blood-brain barrier. The blood-brain barrier protects the CNS (central nervous system) from toxins, pathogens, inflammation, injury, and disease.
The gut microbes also metabolize bile and amino acids to help produce other chemicals that affect the brain. When the body is stressed, it can reduce the production of bile acid by gut bacteria and alter the genes that are involved. When that stress is still creating problems in mind, the gut can develop gastrointestinal issues that will destroy the permeability barrier that is protecting the intestines.
The gut-brain connection plays an essential role in the body�s immune system as it controls inflammation and what passes into the body. Since the immune system controls inflammation, if it is turned on for too long, inflammation can occur as well as several brain disorders like depression and Alzheimer�s disease. Stress can even disrupt the gut by causing contractions to the GI tract, make inflammation worse in the intestinal permeability, and making the body more at risk to infections.
When the body starts to alleviate stress, it can naturally heal itself, and the gut-brain connection can begin functioning normally. With changes in a person�s eating habits and lifestyle, it can drastically change a person�s mood and recover from intestinal ailments they may have. If the brain feels right, then the gut feels good as well. They work together side by side to make sure that the body is functioning correctly. When either one is being disrupted, then the body does not function properly.
Conclusion
Therefore, the gut-brain connection is vital to the body. Neurotransmitters and other components that are in both systems work together to make sure that the body is working correctly. When one of the connections is being disrupted, however, the body can develop many chronic illnesses even if the person seems fine. By altering little things like changing a person�s diet and lifestyle, it can help improve the body and bring the balance back to the gut-brain connection.
In honor of Governor Abbott’s proclamation, October is Chiropractic Health Month. To learn more about the proposal on our website.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues as well as functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or chronic disorders of the musculoskeletal system. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .
References:
Anguelova, M, et al. �A Systematic Review of Association Studies Investigating Genes Coding for Serotonin Receptors and the Serotonin Transporter: I. Affective Disorders.� Molecular Psychiatry, U.S. National Library of Medicine, June 2003, www.ncbi.nlm.nih.gov/pubmed/12851635.
Bravo, Javier A, et al. �Ingestion of Lactobacillus Strain Regulates Emotional Behavior and Central GABA Receptor Expression in a Mouse via the Vagus Nerve.� Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 20 Sept. 2011, www.ncbi.nlm.nih.gov/pubmed/21876150.
Carabotti, Marilia, et al. �The Gut-Brain Axis: Interactions between Enteric Microbiota, Central and Enteric Nervous Systems.� Annals of Gastroenterology, Hellenic Society of Gastroenterology, 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4367209/.
Daneman, Richard, and Alexandre Prat. �The Blood-Brain Barrier.� Cold Spring Harbor Perspectives in Biology, Cold Spring Harbor Laboratory Press, 5 Jan. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4292164/.
Herculano-Houzel, Suzana. �The Human Brain in Numbers: a Linearly Scaled-up Primate Brain.� Frontiers in Human Neuroscience, Frontiers Research Foundation, 9 Nov. 2009, www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/.
Lucas, Sian-Marie, et al. �The Role of Inflammation in CNS Injury and Disease.� British Journal of Pharmacology, Nature Publishing Group, Jan. 2006, www.ncbi.nlm.nih.gov/pmc/articles/PMC1760754/.
Mayer, Emeran A, et al. �Gut/Brain Axis and the Microbiota.� The Journal of Clinical Investigation, American Society for Clinical Investigation, 2 Mar. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4362231/.
Mayer, Emeran A. �Gut Feelings: the Emerging Biology of Gut-Brain Communication.� Nature Reviews. Neuroscience, U.S. National Library of Medicine, 13 July 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3845678/.
Mazzoli, Roberto, and Enrica Pessione. �The Neuro-Endocrinological Role of Microbial Glutamate and GABA Signaling.� Frontiers in Microbiology, Frontiers Media S.A., 30 Nov. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC5127831/.
Pellissier, Sonia, et al. �Relationship between Vagal Tone, Cortisol, TNF-Alpha, Epinephrine and Negative Affects in Crohn’s Disease and Irritable Bowel Syndrome.� PloS One, Public Library of Science, 10 Sept. 2014, www.ncbi.nlm.nih.gov/pubmed/25207649.
Rooks, Michelle G, and Wendy S Garrett. �Gut Microbiota, Metabolites and Host Immunity.� Nature Reviews. Immunology, U.S. National Library of Medicine, 27 May 2016, www.ncbi.nlm.nih.gov/pubmed/27231050.
Sahar, T, et al. �Vagal Modulation of Responses to Mental Challenge in Posttraumatic Stress Disorder.� Biological Psychiatry, U.S. National Library of Medicine, 1 Apr. 2001, www.ncbi.nlm.nih.gov/pubmed/11297721.
Yano, Jessica M, et al. �Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis.� Cell, U.S. National Library of Medicine, 9 Apr. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4393509/.
As a doctor who practices functional medicine, Dr. Jimenez utilizes the Neural Zoomer Plus. This is a blood test that analyzes neurological autoantibodies which offer very specific antibody-to-antigen recognition. The Neural Zoomer Plus tests the reactivity an individual has to 48 neurological antigens. These neurological antigens may be related to neurological disease and can help individuals assess the presence of a neurological condition.
There are 48 markers that are measured and they can be summed up and categorized into 7 larger groups. These groups include demyelination antigens, blood-brain barrier disruption, optical and autonomic nervous system disorders, peripheral neuropathy, neuromuscular disorders, brain autoimmunity, brain inflammation, and infections. (For a full list of the markers that the Neural Zoomer Plus measures, click here).�
The truth of the matter is that autoimmune disorders affect 5-10% of the general population and can target virtually and structure within the central or peripheral nervous system. Symptoms of an autoimmune disorder involving the CNS/PNS include but are not limited to:�
Having the tools to prevent a disease or disorder can be life-changing. With the ability to assess these markers, the rate of cognitive decline can steadily reduce. If you suffer from any of the above symptoms, the Neural Zoomer Plus may be right for you.
The intention of having our patients complete a Neural Zoomer Plus is to help us detect an individual’s IgA, IgG, and IgM sensitivity to antigens, down to the peptide level. Once we receive the results, not only do we have a resource that aids in the early detection of neurological diseases, but we also have a path. This path allows us to create a personalized prevention plan that will focus on the patient along with their lifestyle. – Kenna Vaughn, Senior Health Coach�
The Neural Zoomer Plus is a blood test that is designed to test 48 neurological antigens. When testing for these antigens, the results these markers find can help physicians determine if a patient is at risk for neurological conditions later on. To view last week’s article containing a full list of the signs and 48 markers, click here.�
When a patient comes to us with concerns, we listen very intently and make sure our patient’s concerns are addressed. More often than not, patients reveal they are having issues that relate to neurological declines, such as, muscle spasms or memory loss. With symptoms like these, the patient is referred to get a Neural Zoomer Plus.�
Once we receive the results back, it is compiled into a large report. From here, we assess it and go through all of the markers with an additional team of clinicians. An example of a few of the markers tested in a Neural Zoomer Plus is below. One can see that this patient has an elevated �Anti-Voltage gated potassium channel�. Anti- Voltage-gated potassium channels are responsible for multiple cellular processes such as cell growth and differentiation.�
After analyzing the data, we take these findings and create a treatment protocol that is specific to each patient and their lifestyle. Due to the fact that this patient shows an elevation in specific markers, there are certain adjustments we make in order to help prevent or reverse the cognitive and physical effects of neurological disorders.�
The first step we take is to change the diet of the patient. Many foods are not properly digested, leading to gut inflammation, which further leads to �leaky gut� which then enters the bloodstream and into the blood-brain barrier, causing neurological decline. In order to reverse these effects, we want to make sure the gut is getting the proper nutrients from foods that will not cause inflammation. For this patient, we recommend the Wahls Protocol.�
The second step we take is to usually get the patient involved in a more active lifestyle. By having this patient start to exercise with activities like yoga, it can improve the state of mind and their mind-body connection.�
The third step is usually nutraceuticals. These are supplements that will naturally help the body and brain with no addictive or harsh chemicals. With every patient, the nutraceuticals and amount needed vary depending on their specific body. For this case, we recommend:��
N-acetyl-L-cysteine:� (NAC) is a precursor to glutathione, the body�s most important cellular�antioxidant. NAC supplements have been shown to increase cellular glutathione levels.
Vitamins B12, B6, and folate: These are metabolic cofactors important for cellular metabolism and maintenance of all tissue cell types, but particularly important to nerve cells. Deficiencies in�B12 or folate can raise homocysteine levels, which have been associated with a higher risk for�vascular disease and dementia.
Alpha Lipoic Acid:� (ALA) is an essential cofactor in normal cellular metabolism and cellular�energy production.
Vitamin C and vitamin E: Can reverse symptoms caused by vitamin C and E�deficiencies.
As mentioned before, each patient is different and their lab work shows varying needs. However, with the Neural Zoomer Plus, we are able to get ahold of these symptoms, create a personalized treatment plan, and get them under control.�
As one can see, the data and knowledge we gain from these tests are truly eye-opening and give us an early advantage to help reverse or aid in prevention methods. We take the needs and concerns of every patient very seriously and work extremely hard to figure out the right method of treatment for them. Our goal is to help ensure that this lifestyle change is as smooth and easy on the patient as possible so they can get back to enjoying the activities they love and spending time with loved ones. The transition into a new lifestyle can be stressful, but with the information we gain from the tests, the knowledge we use from the doctor, and the willingness to change from the patient, we are set up to be the best team you can have to get your life back! – Kenna Vaughn, Senior Health Coach�
Until only several decades ago, neuroscientists believed that the brain stopped creating new neural connections, meaning that your memory starts to become irreversibly worse when the human body stopped developing, which is generally in your early 20s.� Neuroscientists also understood that neurons weaken and die as we age. The loss of brain function due to neural breakdown was believed to be a normal part of aging until recent research studies demonstrated the opposite of this belief. �
Over the last several years, it has become evident to neuroscientists that you can, as a matter of fact, create new neurons and develop new neural connections starting in your early 20s and continuing well into your old age. As the older regions of the brain start to wear out, you can ultimately rewire your brain and improve your overall brain health. But, how can you improve brain health? In the following article, we will discuss 5 ways you can improve your brain health and promote your well-being. �
Eat Healthy Foods
You are what you eat, or at least, your brain can be affected by the types of foods you eat. Eating junk food can have a tremendous impact on your brain health because trans fats and saturated fats, frequently found in processed foods, can negatively alter the brain’s synapses. Synapses connect the brains neurons and are fundamental for memory and learning. But, a balanced diet rich in omega-3 fatty acids, which are found in salmon, walnuts, and kiwi, can provide the synapses with a boost which can ultimately help fight against neurological diseases, including depression, dementia, and Alzheimer’s disease. �
Participate in Exercise
Participating in exercise and physical activity can also help boost your memory and help you think more clearly, reducing the risk of developing neurological diseases. Because exercise and some physical activity is a moderate stressor to the body, which uses energy needed by the brain, it triggers the release of substances, known as growth factors, which make the brain’s neurons fitter and stronger. Participating in 30 minutes of exercise or physical activity every other day can help improve brain health, and don’t forget to stretch. Stretching can help reduce anxiety, which can affect overall brain health. �
Mental Stimulation
Make sure to also give your brain a workout with brainteasers, crossword puzzles, and memory games. Research studies have demonstrated that using these tools to remain mentally active can help reduce the risks of developing dementia and other neurological diseases by building and maintaining a reserve of stimulation on your brain. Mental stimulation can help boost the regions of your brain which control and regulate learning and attention, which are hard-wired into the brain. �
Memory Training
Maintaining information stored in your memory banks and retaining that memory with age may also be a simple matter of mind control. By way of instance, confidence in your cognitive abilities might actually influence how well your memory works, especially for the elderly. Because many older adults tend to blame memory lapses on age, regardless of whether or not that is the reason, they may often be keeping themselves out of even trying to remember. Prediction can also enhance memory. If you have an idea of the information you have to remember afterward, you’re more likely to remember it. �
Get Enough Sleep
Getting enough sleep can help improve your overall well-being, especially your brain health. Sleep gives your brain an opportunity to match the memories of the day and combine them for long-term storage. One research study demonstrated that the brain can perform its reviewing much quicker when you are asleep than when you’re wide awake. A 90-minute mid-afternoon nap can help store long-term memories, such as events or skills you are attempting to master. Research studies have demonstrated that developing Alzheimer’s disease and other types of dementia are generally due to genetics. �
One research study, presented in July at the Alzheimer’s Association’s International Conference on Alzheimer’s Disease, demonstrated a connection between moms who develop Alzheimer’s disease and the chances that their children will develop the health issue in older age. Another research study suggests that a pattern of proteins is a risk factor for neurological disease. But, no one can predict who will develop dementia. While neuroscientists discover better treatments for these health issues, following ways to improve brain health is probably the best you can do to promote your overall well-being. �
Many neuroscientists once believed that the brain stopped developing new neurons and new neural connections as soon as you reached adulthood. However, recent research studies have demonstrated that we can create new neurons and new neural connection which can continue well into your old age.�In the following article, we discuss 5 ways you can improve your brain health and promote your well-being. From eating healthy foods to getting enough sleep, maintaining your overall well-being can help improve your brain health. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
The purpose of the article above is to demonstrate 5 ways which can ultimately help improve your overall brain health. Neurological diseases are associated with the brain, the spine, and the nerves. The scope of our information is limited to chiropractic, musculoskeletal and nervous health issues as well as functional medicine articles, topics, and discussions. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 . �
Curated by Dr. Alex Jimenez �
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance.
Formulas for Methylation Support
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Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
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If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
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A majority of individuals today are aware about the gut-brain connection and how approximately 90 percent of their body’s serotonin is really generated in the gastrointestinal, or GI, tract as well as the way the gut-brain axis is associated with depression. Overall gut health involving a healthy population of gut microbiota can affect many facets of our well-being, therefore, it’s no mystery that the connection between the gut and chronic health issues, such as cardiovascular disease, diabetes and neurodegenerative diseases, are also significantly strong.
Berberine, an ancient mixture frequently utilized in a variety of medicinal herbs throughout several traditional treatments has been demonstrated to benefit as well as link the gut and the heart. Berberine is an isoquinoline derivative alkaloid found in numerous herbs. Although these berberine-containing herbs aren’t traditionally utilized in food preparations, the active ingredient has been identified and may be isolated from a variety of plant sources, such as Coptis chinensis, or Coptis or Goldthread, Hydrastis canadensis, or goldenseal, Berberis aquifolium, or Oregon grape, Berberis aristata, or Tree Turmeric, Berberis vulgaris, or Barberry, and Arcangelisia flava.
Berberine is most favorably known for its function in gut health, demonstrating activity which can help support gut microbial balance. In fact, scientists have shown a growing interest in many plant-derived compounds which affect bacterial direction and berberine is a pioneer in the group. Additionally, its a botanical proven to influence blood glucose, blood lipids and also the immune system. Researchers today have learned how berberine can provide these tremendous benefits.
Gut Health Equals Heart Health
According to evidence from a 2016 research study, the gut’s immune system is fundamental towards preventing a variety of diseases and it may often contribute to metabolic disorders. However, it might also help provide a treatment goal when observing systemic inflammation in insulin resistance. Moreover, modified gut immunity has been linked with changes to the gut microbiota, intestinal barrier function, gut-residing immune cells, and resistance to antigens which enter the gastrointestinal, or GI, system. Although this has been previously believed to raise the danger of esophageal ailments including, pathogenic infections and chronic inflammation, which may ultimately lead to chronic health issues.
In our currently hectic and stressful world, a growth in the numbers of chronic disease has begun to negatively affect our overall health health. The best instance of this increase in chronic illness is type 2 diabetes, abbreviated in this article as T2DM, which often coexists with hypertension and causes individuals to pursue nutritional advice in order to achieve healthy blood sugar levels. The information viewing T2DM alone are shocking. As of 2015, the Center for Disease Control and Prevention reported that over 30 million people in the United States had diabetes, where approximately three times as many had pre-diabetes. According to statistics, 70 percent of individuals with pre-diabetes will develop type 2 diabetes.
Natural remedies and botanicals utilized as herbal treatments which have been previously used to promote healthy blood sugar levels have been strongly evaluated in order to determine their safety and effectiveness. Numerous berberine research studies are being conducted, though these are mostly in vitro, or in cell cultures. A majority of in vivo research studies have used animals for the analysis. Despite the quality and size of those research studies, virtually all of the outcome measures throughout the last two decades are positive. One research study from 2012 looked at in vitro results to thoroughly assess the assumed mechanism of action by which berberine affects fat storage. The outcome measures using clinical therapeutics of berberine to observe participants with metabolic syndrome appeared promising.
Another research study evaluated and analyzed the use of berberine in human cell cultures to ascertain how it influenced preadipocyte, a precursor to fat cells, comparison and fat hormone as well as cell activity in patients with metabolic disease. The researchers demonstrated that preadipocyte differentiation was restricted by berberine, while leptin, adiponectin, PPAR?2, or the nuclear receptor known as the master regulator of fat cell biology and target of many diabetes drugs and/or medications, and C/EBP?, a protein necessary for fat cell differentiation, diminished. After several months, participants demonstrated a drop in their BMI and leptin/adiponectin ratio, showing that berberine could boost insulin sensitivity by limiting fat storage, which may also have beneficial effects in the regulation of blood lipid levels.
Concerning how berberine affects cardiovascular biomarkers, many assessments can be found in the literature. The administration of berberine in one analysis generated a substantial decrease in total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, with a marked rise in high-density lipoprotein. Furthermore, a meta-analysis of this anti-diabetic, hypolipidemic and anti-inflammatory effects of berberine were reviewed in twenty-seven randomized controlled clinical trials. The researchers have concluded that berberine is safe and effective due to its support of the cardiovascular system and the maintenance of healthy blood sugar levels, without any severe adverse reactions found in some of the other research studies. Berberine has also been demonstrated to restrict complex I of the mitochondrial respiratory chain, leading to a growth of 5′ adenosine monophosphate, or AMP and 5′ adenosine monophosphate-activated protein kinase, or AMPK activation. This seems to have a direct impact on energy metabolism as well as that in other structures and functions.
The neurological health effects of berberine have also been considered, particularly from the modulation of the dopaminergic system. Berberine has also demonstrated a possibility in the successful management of seizures, diabetes-induced memory malfunction and hyperexcitability. One animal research study investigating obsessive-compulsive disease found that berberine can promote anti-compulsive and/or anxiolytic effects because of its ability to boost brain monoamine levels. Another review from 2016 demonstrated berberine’s ability to reduce oxidative stress and supply neuroprotective benefits. The review further cites research studies which examine the botanical’s function in the evolution of amyloid plaques and intracellular neurofibrillary tangles. Berberine has found its function in the gastrointestinal, cardiovascular as well as brain worlds. Truly offering a wholesome dose of gut-heart-brain link, berberine is definitely one to consider.
Dr. Alex Jimenez’s Insight
Research studies have found that the relationship between a healthy gut, brain and heart is fundamental towards overall well-being. Natural remedies and botanicals, such as berberine, can help promote as well as support this gut-brain-heart connection, while other alternative treatment options, such as chiropractic care, can restore balance and encourage the human body’s natural healing abilities by correcting spinal misalignments of the spine. Furthermore, by establishing the proper relationship between the brain, the spinal chord and the rest of the body, chiropractic care can help regulate the proper structure and function of each system in the human body.
With the increasing number of gut health issues, it’s become a priority to find safe and effective treatment options to properly address these common problems. More and more research studies have found a connection between the gut, brain and heart. As previously mentioned, by both supporting and promoting the well-being of the gastrointestinal, or GI, system, the structure and function of a variety of other systems can be sustained. Natural remedies and botanicals, such as berberine, have been utilized for centuries as herbal treatments, however, other alternative treatment options can also be used to help improve gut health. Chiropractic care is a well-known, alternative treatment option which has been demonstrated to help promote the natural healing of the human body through the use of spinal adjustments and manual manipulations as well as other therapeutic techniques to correct spinal misalignments, or subluxations. Moreover, a doctor of chiropractic, or chiropractor, can recommend a series of lifestyle modifications, including exercise and nutritional advice, in order to help further improve the overall health and wellness of the human body. Maintaining the well-being of the gut can help boost brain and heart health as well.
Berberine Warnings
In large doses, berberine may lead to gastrointestinal irritation. Thus, it’s typically administered in divided doses and taken with a meal. In addition, researchers have revealed that berberine can limit particular cytochrome enzymes that also target a lot of different kinds of drugs and/or medications, including certain antibiotics. Inhibiting cytochrome enzymes influences the liver’s detoxification system, which will be required to metabolize and, finally, clear drugs and/or medications. For this reason, it’s essential to carefully monitor those patients that are using berberine if other medicines are used concomitantly. The scope of our information is limited to chiropractic as well as to spinal injuries and conditions. To discuss the subject matter, please feel free to ask Dr. Jimenez or contact us at�915-850-0900�.
Curated by Dr. Alex Jimenez
Additional Topics: Back Pain
Back pain is one of the most prevalent causes for disability and missed days at work worldwide. As a matter of fact, back pain has been attributed as the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience some type of back pain at least once throughout their life. The spine is a complex structure made up of bones, joints, ligaments and muscles, among other soft tissues. Because of this, injuries and/or aggravated conditions, such as herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief.
Alzheimer’s disease claims nearly twice as many American lives annually as it did just 15 years ago, a new report shows.
“And that’s frankly alarming,” said Keith Fargo, director of scientific programs and outreach at the Alzheimer’s Association, which produced the report. “Now, a lot of people will think it’s because we’re living longer,” he added. “And there is some truth to that. But there’s also an assumption that we should just expect to get Alzheimer’s disease as we get older. And that’s not true.
“Most people do not get Alzheimer’s, even if they live into their 80s or 90s. It’s not normal. It’s not something that we should accept. We’ve definitely got to do something about it,” Fargo said.
The Cost of Alzheimer’s Disease
The report also found that more than 5 million American seniors aged 65 and older now live with the memory-robbing disease. That represents approximately 10 percent of all the nation’s seniors, and that number is projected to jump to nearly 14 million by 2050. In fact, nearly half a million seniors are expected to develop the disease in 2017 alone.
Another 200,000 Americans under the age of 65 also struggle with the disease, the report found. And those statistics come with a hefty price tag: It costs $259 billion a year for Alzheimer’s care. That amount is expected to reach $$1.1 trillion by 2050, the report estimated.
Dr. Anton Porsteinsson is director of the Alzheimer’s Disease Care, Research and Education Program at the University of Rochester School of Medicine in Rochester, N.Y. He said the rising numbers likely reflect a number of different factors in play.
“Partly, it is due to increasing numbers of older individuals, partly due to success in treating other leading causes of death, and partly due to increasing awareness that AD [Alzheimer’s] is a lethal disease,” Porsteinsson said.
Among the report’s additional findings: Alzheimer’s is now the fifth leading cause of death among seniors; the sixth leading cause of fatalities among all Americans; and the only disease among the nation’s top 10 biggest killers for which there is no prevention, no way to slow progression and no cure.
“And the costs are now completely out of control,” added Fargo, with the total annual cost for Alzheimer’s and dementia care in excess of a quarter trillion dollars.
Another highlighted concern: the “especially burdensome” ordeal Alzheimer’s caregivers experience while attending to the needs of loved ones as the patient suffers across-the-board mental and physical decline.
In 2016, more than 15 million Alzheimer’s caregivers provided just over 18 billion hours of unpaid care, valued at $230 billion.
Alzheimer’s Disease: Mental and Physical Decline
And those caregivers suffer their own health consequences: More than a third (35 percent) report their health has worsened since assuming caregiver duties, compared with 19 percent of caregivers for older people without dementia. Depression and anxiety also plague dementia caregivers more often, the report found. Still, the report was not entirely bleak, spotlighting growing efforts to identify telltale signs of developing disease.
The goal is to hone in on neurological signs — including changes in brain size, shifts in spinal fluid content, and/or the growth of nerve plaques in the brain — that could allow rapid detection of pre-symptomatic Alzheimer’s.
“It’s a window into the future,” Fargo said. “If you ask where Alzheimer’s disease research is headed, that’s where it’s headed.” “We believe that in the coming years we’ll have tests that you can do in the doctor’s office that will let you know your risk for Alzheimer’s,” he noted. And that, he suggested, “could open the door for prevention.”
Fargo noted that, even in the absence of effective treatments or a cure, early diagnosis would be a boon for research and would give patients a head start on planning for their future. Yet, Porsteinsson suggested that the future of these telltale signs, known as biomarkers, remains unclear.
“Biomarkers are particularly important when it comes to research and development of future potential treatments,” he said.
On the other hand, he stressed that “the utility of biomarkers in current care is intensely debated.
“The biomarkers are expensive,” Porsteinsson noted. “And it is a question how much a positive or negative finding will change approach to care. “Having said that,” he added, “it often matters greatly to patients and their families to know exactly what they have and what to expect.”
SOURCES: Keith Fargo, Ph.D., director, scientific programs and outreach, Alzheimer’s Association, New York City; Anton Porsteinsson, M.D., professor, psychiatry, and director, Alzheimer’s Disease Care, Research and Education Program, University of Rochester School of Medicine, Rochester, N.Y.; March 7, 2017, 2017 Alzheimer’s Disease Facts and Figures
The scope of our information is limited to chiropractic and spinal injuries and conditions. To discuss options on the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .
Brain injuries are common complications in our modern world. Approximately 2 million individuals experience a head injury in the United States alone each year. Although most brain or head injuries are not considered life threatening, they could sum up to billions of dollars in annual revenue. Brain injuries are often categorized according to patient response. Only 1 out of 4 reported brain injuries are considered moderate or severe.
Just put one foot in front of the other and you’ll boost your brain at the same time.
That’s the conclusion of a small study that found the impact of a foot while walking sends pressure waves through the arteries that increases blood supply to the brain. “New data now strongly suggest that brain blood flow is very dynamic,” said researcher Ernest Greene and his colleagues at New Mexico Highlands University.
Activities such as bicycling, walking and running may optimize brain function and overall sense of well-being during exercise, the researchers said.
How Exercise Regulates Circulation to the Brain
Blood supply to the brain was once considered an involuntary action that wasn’t affected by exercise or changes in blood pressure. Previous research has shown, however, that the foot’s impact while running is associated with backward-flowing waves in the arteries that help regulate circulation to the brain. These waves are in sync with the runner’s heart rate and stride, the study authors explained.
For the new study, scientists examined the effects of walking, which involves a lighter foot impact than running.
Using ultrasound technology, they measured the carotid-artery diameter and blood velocity waves of 12 healthy young adults to calculate the blood flow to their brains as they walked at a steady pace. The participants were also assessed at rest.
The study showed that walking results in a significant increase in blood flow to the brain. The boost in blood flow isn’t as dramatic as with running, but it’s more notable than that seen with biking, which doesn’t involve any foot impact, the study authors said.
“What is surprising is that it took so long for us to finally measure these obvious hydraulic effects on cerebral blood flow,” said Greene, the study’s first author. “There is an optimizing rhythm between brain blood flow and ambulating [walking]. Stride rates and their foot impacts are within the range of our normal heart rates [about 120/minute] when we are briskly moving along,” Greene said in a news release from the American Physiological Society.
The study’s findings were expected to be presented Monday at the society’s annual meeting, in Chicago. Results of studies presented at meetings are usually considered preliminary until published in a peer-reviewed medical journal.
SOURCE: American Physiological Society, news release, April 24, 2017
The scope of our information is limited to chiropractic and spinal injuries and conditions. To discuss options on the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .
Additional Topics: What is Chiropractic?
Chiropractic care is an well-known, alternative treatment option utilized to prevent, diagnose and treat a variety of injuries and conditions associated with the spine, primarily subluxations or spinal misalignments. Chiropractic focuses on restoring and maintaining the overall health and wellness of the musculoskeletal and nervous systems. Through the use of spinal adjustments and manual manipulations, a chiropractor, or doctor of chiropractic, can carefully re-align the spine, improving a patient�s strength, mobility and flexibility.
IFM's Find A Practitioner tool is the largest referral network in Functional Medicine, created to help patients locate Functional Medicine practitioners anywhere in the world. IFM Certified Practitioners are listed first in the search results, given their extensive education in Functional Medicine
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