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Integrative Functional Wellness

El Paso Back Clinic & Integrative Functional Wellness Team.
Chiropractic Doctors provide preventative care to help establish healthy habits in patients at all stages of their lives. For example, posture analysis can help identify posture habits that can greatly impact overall health, including energy levels, breathing, stress, and sleep. Chiropractic medicine is a form of integrative medicine that focuses on natural, non-invasive, evidence-informed practices of disease prevention and health promotion.

Through a broad scope of assessment and treatment modalities such as manipulation, functional medicine, physical rehabilitation therapy, targeted nutritional and botanical care, acupuncture, and diet/lifestyle management, chiropractic medicine can effectively treat a wide range of conditions and improve overall health. Functional Nutrition focuses on optimizing cellular and metabolic function for optimal health. Functional Medicine Practitioners specialize in helping uncover the root causes for imbalances that may be contributing to past, current, and even future conditions.

General Disclaimer *

The information herein is not intended to replace a one-on-one relationship with a qualified healthcare professional or licensed physician and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.

Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. In addition, we provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure.

We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system. Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.*

Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. In addition, we provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed in: Texas & New Mexico*


The Factors Of Increased Immunity

The Factors Of Increased Immunity

With everything that is going on in today’s world immunity is especially important. Without a properly functioning immune system, our bodies can become inflamed and more susceptible to viruses. Inflammation can cause a weakened immune system, joint pain, headaches, fatigue and more!

So what can we do to build up our immunity and help give our bodies a fighting chance? First off, washing your hands is highly important. Not just now, but always. Be sure to wash your hands with warm water and scrub everywhere. Second, get plenty of sleep. Rest is how the body recovers. If you do not give your body adequate sleep, the strength you’re cells have to fight off infection lessens. Third, eat healthy food, hydrate, and exercise. Finally, last but not least help kick up your immune system by supplementing the body with all-natural supplements.

There are many supplements that will be beneficial to the body. However, two of the most important are NAC and Glutamine.

 

What Are They?

 

NAC stands for N-acetyl-Cystine. NAC is an amino acid that the body can produce but the body can also greatly benefit from taking additional NAC in supplemental form. NAC plays an important role in helping the liver to detox. In addition to this, NAC helps to replenish the glutathione levels in the lungs and can help to reduce the inflammation. This is highly beneficial in helping to relieve the symptoms of a respiratory infection.

NAC is also greatly beneficial in boosting brain health. NAC helps to regulate glutamate levels and replenish glutathione. However, one of the most important factors of NAC is its ability to boost Glutathione levels.

Glutamine is an amino acid that helps the body perform many functions. Glutamine plays a crucial part in the immune system.

 

The Connection & How It Impacts Immunity

 

However, one of the most important factors of NAC is its ability to booze Glutathione levels. NAC and glutathione can help to boost an individual’s immune health. In research studies shown, NAC has been shown to lessen the effects of a virus and its ability to replicate. When it comes to immunity NAC and Glutamine are powerful molecules. Stoping the replication of a virus can help reduce the spread and the length of the virus in an individual.

Many infections and diseases have been linked to low glutathione levels. When the glutathione levels are low this is typically due to enhanced oxygen radicals. Studies have been done and show that when supplementing NAC to those who have low glutathione levels, it directly boosts their levels and helps with infection.

Especially with everything happening today, we want to increase our immunity and decrease the inflammation in the body.� Essentially, think of the body as a road trip. For this trip we need two main things: the gas for the car, and the car to take you to the end destination.� NAC is the gas that drives the car. We need the gas to get to our end destination. Our end destination is being healthy and giving our body the best chance to fight off infection (increased Glutathione). So by giving our body gas (NAC) we provide it with what it needs to take us to where we want to go (increased Glutathione, leading to increased immunity).

 

How Can I Benefit?

 

Overall, NAC is great to decrease inflammation. Inflammation is an extremely common underlying issue relating to other health conditions individuals suffer from. By providing your body with additional supplements, you can help increase your immunity and decrease your chances of contracting a virus and/or the length of the virus. Always discuss supplements with your primary care doctor before you begin them, but consider adding these into your daily routine!

I always recommend talking to your primary care provider and taking supplements daily. Supplements, in general, are a great way to help provide the body with the essential vitamins and minerals you may be missing. However, now more than ever supplementation is key. By building up and providing the body with the nutrients it needs for proper function, it will help prepare your body to fight off an infection. Supplementation like NAC is great to have already running in your system to help combat an infection if you were to catch one. Remember to be smart, talk to a primary care doctor before beginning supplementation, and keep in mind that not all supplements are created equal.� -Kenna Vaughn, Senior Health Coach��

The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�

References:
Dinicola S, De Grazia S, Carlomagno G, Pintucci JP. N-acetylcysteine as powerful molecule to destroy bacterial biofilms. A systematic review.�Eur Rev Med Pharmacol Sci. 2014;18(19):2942�2948.
Goodson, Amy. �Top 9 Benefits of NAC (N-Acetyl Cysteine).� Healthline, 2018, www.healthline.com/nutrition/nac-benefits#section3.
Wessner B, Strasser EM, Spittler A, Roth E. Effect of single and combined supply of glutamine, glycine, N-acetylcysteine, and R,S-alpha-lipoic acid on glutathione content of myelomonocytic cells.�Clin Nutr. 2003;22(6):515�522. doi:10.1016/s0261-5614(03)00053-0

The Role Of Nrf2 and Inflammation

The Role Of Nrf2 and Inflammation

If there is one thing we are learning more and more about, it is that everything can be related back to inflammation and what we put inside our bodies. Point blank. The food you consume affects your genetics and your inflammatory response in the body. Headaches, achy joints, and overall fatigue have been directly linked to inflammation.

Inflammation

Inflammation was once thought to just be something that occurs when the body has an infection or we hurt ourselves as the body’s natural response. That fact is still true to this day. However, we now know more. Now, we are able to recognize inflammation occurring inside our organs and down to the cellular level.

Just as you roll your ankle and it becomes inflamed, if you eat the wrong foods your gut becomes inflamed. This can then be traced back to leaky gut and in some cases, autoimmune diseases.

So what can we do about it? What is actually happening in our bodies?

The human body is an amazing machine that we are still finding more about each and every day. Let’s first take a look at where this inflammation is coming from. Inflammation can enter the gut barrier as a toxin, protein, pathogen, LPS, or alcohol.

If our body is continuously exposed to these triggers, it can result in our immune system becoming dysregulated. Now that our body has these triggers, things like allergies, asthma, autoimmunity, and poor immune tolerance and regulation become our bodies new regular.

Amplifying Loop

These triggers then signal something called cytokines. Cytokines are tiny and dance around inside of the cell. These cytokines increase NF-kB activity.

NF-kB is then used to transcribe DNA and express an inflammatory state!

Now, our bodies are promoting inflammation, all because we let the toxins in. What we put into our mouth and our bodies matter. The foods we eat have the ability to provide nutrients to our cells, rather than facilitating in this ongoing inflammatory response chain.

How Do I Regain Control?

Nrf2 is a key protein in the body that has the function of regulating the genome. This helps the body balance gene expressions and the regulation of our genes. Another thing Nrf2 does is upregulate genes that encode antioxidant enzymes and antiinflammatory genes.

Essentially, Nrf2 helps to fight off inflammation and reduce oxidative stress. Nrf2 activity is part of the detoxification system our bodies naturally have. It helps us to not get sick from every single bacteria we come into contact with. However, Nrf2 is a pathway, not a supplement. So now the question becomes, How do we active Nrf2?

From The Kitchen to The Genes

As mentioned earlier, everything can be traced back to the kitchen and what we put into our mouth to nourish our body. A great way to ensure you are feeding your body what it needs is to make a smoothie in the morning. Smoothies can contain so many nutrient-dense foods to aid in Nfr2 activation.

First, start off with flaxseed in the blender. Blend it up so the flax seeds get broken up and open. Next, add in blueberries, raspberries, strawberries, acai berry powder, broccoli sprouts, and almond milk!

By providing your body and your cells with the nourishment they need, they will flourish. In addition to a smoothie, there are supplements that can aid in Nrf2 activation as well. These supplements include curcumin, fish oil, wormwood, and CoQ10.

It’s clear that the “American Diet” has been causing problems for us. The world is so busy and fast-paced that we are not taking the time or giving our bodies the consideration to shop and make nutritious home-cooked meals. We need to increase our vegetables, fruits, fibers, whole grains and decrease the carbs. Everyone has some degree of inflammation in their body, and many of us do not even realize it! I challenge us to give up fast food for an entire month, cut the soda, increase the lemon water and eat at least one salad a day during this month. By increasing our vegetables and creating plates that are more colorful, our bodies will thank us! – Kenna Vaughn, Senior Health Coach�

References:
Gordon, Jacob. �Recipes for NRF2 – MyBioHack: Unlock Your Maximum Potential.� MyBioHack, MyBioHack | Unlock Your Maximum Potential, 7 Nov. 2017, mybiohack.com/blog/recipes-for-nrf2.
Gordon, Jacob. �Why NRF2 Activation Can Make You More Sick – MyBioHack: Unlock Your Maximum Potential.� MyBioHack, MyBioHack | Unlock Your Maximum Potential, 2 Feb. 2020, mybiohack.com/blog/nrf2-cirs-sensitivities.
Lawrence, T. �The Nuclear Factor NF-�B Pathway in Inflammation.� Cold Spring Harbor Perspectives in Biology, vol. 1, no. 6, 2009, doi:10.1101/cshperspect.a001651.
Ma, Qiang. �Role of Nrf2 in Oxidative Stress and Toxicity.� Annual Review of Pharmacology and Toxicology, vol. 53, no. 1, 2013, pp. 401�426., doi:10.1146/annurev-pharmtox-011112-140320.

The scope of our information is limited to chiropractic, musculoskeletal,and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at915-850-0900.

Stubborn Weight: Genetics or Diet?

Stubborn Weight: Genetics or Diet?

Today, there can be a lot of confusion when it comes to diet. The information received can be contradicting, confusing, and leave individuals feeling lost. This can often result in giving up on the diet and being left with joint pain, inflammation, discomfort, headaches and more.

The reason why there is more than one diet out there is because the research is always advancing. We have come to realize that everyone’s body reacts to different food sources and diets differently.

Genetic Code

As more and more research is being done, the more we are realizing how the genetic factor of individual cells directly correlate to a patient’s weight, diet, and changes as they age. For years, as one would get older and start gaining weight, we would attribute it to age. Although age is a factor, what we are finding now is that the genes are actually changing as we age and that is what creates this weight gain.

Sure enough, there are also genes that will tell us if you are susceptible to snacking. These genes can detect if you have a predisposition for heightened snacking or satiety. Satiety is the feeling of fullness after a meal. If you have reduced satiety, you tend to snack more because you do not feel as full after the meals you eat.

Getting your genes tested will allow the treatment plans created to be more personal and more geared to see results! Believe it or not, your genes can tell us if you are genetically prone to obesity,� if you have weight loss resistance when it comes to carbohydrates, and how your body responds to exercise! Using the genes, we can see how many hours per week you will need for weight loss or to maintain your current weight.

Proven Methods

The best option is to know your genes so the diet plan can be geared more towards you directly. However, if that is not a possibility right away, there has been one diet that has been proven time and time again to work for almost everyone. This diet is referred to as the Ketogenic Diet.

In simple terms, the ketogenic diet is a low carb, high-fat diet. This diet works by sending the body into a state of ketosis which burns fat as fuel.

Research shows that those using a ketogenic diet demonstrated a higher percentage of weight loss and kept the weight off longer when compared to those who did a low-fat diet.

Available Resources

Considering the fact that there is misinformation about diets out there, proper education is going to be the key. As someone who has gone through dietary changes myself and figuring out what works best with my body with type 1 diabetes for optimal health, the right team is what made me successful.

Surround yourself with those who are continuously educating themselves and have a system in place. For example, we make sure our patients get one on one time with the doctor and a health coach. From here, the health coach and patient become connected through a virtual database allowing the patient’s food, weight, supplements, hydration, BMI, BIA, and activity to be tracked by the health coach. The health coach can then instant message or video chat the patient throughout the week to ensure they are staying on track, staying motivated, and answer any questions they may have!

Do not be left confused over diets anymore! Remember that your genetic code holds the key to the right diet for you.

The right diet has the ability to make individuals see the results they have been waiting for. It all comes down to the genes. As mentioned, genes change over time but they hold the code. If you are someone who has struggled with diets, feeling good, or are stuck at a certain weight, I highly recommend getting tested! The information you gain from this is so beneficial! I have seen the results first hand, and they are eye-opening. They let you know if you have the genetics that will hold onto fat. This knowledge can help us prevent health issues such as metabolic syndrome! – Kenna Vaughn, Senior Health Coach�

Dr. Alex Jimenez�s Blog Post DisclaimerThe scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.

 

REFERENCES
Bueno, Nassib Bezerra, et al. �Very-Low-Carbohydrate Ketogenic Diet v. Low-Fat Diet for Long-Term Weight Loss: a Meta-Analysis of Randomised Controlled Trials.� British Journal of Nutrition, vol. 110, no. 7, 2013, pp. 1178�1187., doi:10.1017/s0007114513000548.

 

Functional Neurology: Migrating Motor Complex (MMC) and SIBO

Functional Neurology: Migrating Motor Complex (MMC) and SIBO

Do you have difficulty digesting protein-rich foods? Do you have difficulty digesting starch-rich foods? Do you have difficulty digesting fatty or greasy foods? Do you experience abdominal distention after meals? Do you have abdominal pain and inflammation? If so, you may be having SIBO symptoms. �

 

Small intestinal bacterial overgrowth (SIBO) is a gastrointestinal (GI) tract health issue that can become a persistent problem if it’s not managed accordingly, especially if it’s ultimately left untreated. For many people suffering from chronic gas, bloating, constipation, and/or diarrhea, they may have also already had a diagnosis of irritable bowel syndrome (IBS). However, research studies have shown that one of the main causes of IBS may be SIBO. �

 

SIBO is a digestive health issue where there are too many bacteria in the small intestine. Bacterial overgrowth can also cause IBS. Although there are many treatment options for SIBO, one of the most important treatments for SIBO is doing everything we can to help keep SIBO from coming back. The purpose of the following article is to discuss how understanding the migrating motor complex (MMC) can help treat small intestinal bacterial overgrowth (SIBO). �

 

What is the Migrating Motor Complex?

The migrating motor complex (MMC) refers to the collection of electrical waves that occur in the gut. The MMC helps regulate several important functions of the gut, such as sweeping out the stuff we no longer need in there and moving it down to the colon where it can then be excreted by the human body. �

 

Phases of the Migrating Motor Complex

The MMC is how the digestive system eliminates waste from the human body. The MMC cycle includes four phases, including:�

 

  • The first phase is a period of calmness that lasts 45 to 60 minutes where rare action potentials and contractions occur.
  • The second phase is a period of about 30 minutes where peristaltic contractions occur and gradually increase in frequency. Peristalsis starts in the stomach and continues throughout the small intestine.
  • The third phase lasts 5 to 15 minutes and it’s made-up of rapid, evenly spaced out peristaltic contractions. The pylorus stays open during these peristaltic contractions which allow many indigestible materials to pass into the small intestine.
  • The fourth and final phase is a period of transition between the contractions from the third phase and the inactivity from the first phase.

 

Gastric, biliary, and pancreatic secretion increases during the MMC to further with the digestion process as well as to help decrease bacteria in the gastrointestinal (GI) tract. Healthcare professionals believe that motilin, the enteric hormone, regulates the MMC. Because eating food can interrupt the MMC, fasting between meals is important to help complete the four phases. Moreover, the well-known �growling” sounds you generally hear when you are hungry may be the migrating motor complex performing its job functions accordingly, such as cleaning your bowels of waste and excessive bacteria. �

 

Migrating Motor Complex (MMC) Health Issues

If the migrating motor complex (MMC) isn’t working properly, the foods we consume may ultimately remain in the stomach and small intestine longer than what is generally considered to be healthy, which can make us feel a heaviness after eating or it can make us feel too-full, even if you’ve only had a small meal. Furthermore, a slow MMC can also cause bacteria to stay in the gastrointestinal (GI) tract for too long, which can also lead to SIBO. � Approximately 70 percent of people with SIBO also have MMC health issues. Research studies have shown that reduced MMC function may be associated with excess methane and/or hydrogen gasses produced by the excess bacteria in the gut. SIBO can also increase inflammation and intestinal permeability. �

 

Other research studies have shown that utilizing acid-reducing medications or an H. pylori infection can affect MMC function. Lack of exercise, grazing, and constipation can also affect MMC. Stress can also affect MMC function. Finally, thyroid problems and adrenal fatigue can also affect MMC function. �

 

Research studies have shown that people with IBS can frequently have decreased MMC function although researchers still don’t understand how these changes occur. Several researchers believe that food poisoning and other bacterial infections can affect the gut microbiome which then changes how the gut microbiome signals the MMC to start and stop. Eating inflammatory foods or foods that you�re sensitive and/or allergic to can also cause nerve damage in the gut. Subsequently, these damaged nerves then can�t properly signal the MMC to function accordingly, leading to SIBO and other health issues. �

 

Dr. Alex Jimenez Insights Image

Small intestinal bacterial overgrowth (SIBO) is a serious health issue which usually occurs because of an underlying chronic health issue. Several common symptoms may ultimately help determine the presence of SIBO. In addition, research studies have demonstrated that poor migrating motor complex (MMC) function, or the collection of electrical waves that help regulate several important functions of the gut, can ultimately cause SIBO and other digestive system health issues if left untreated. SIBO, or small intestinal bacterial overgrowth is treatable. Patients should contact a healthcare professional immediately if they suspect they have SIBO so that they can begin treatment right away. – Dr. Alex Jimenez D.C., C.C.S.T. Insight

 


 

Neurotransmitter Assessment Form

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The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �

 


 

Do you have difficulty digesting protein-rich foods? Do you have difficulty digesting starch-rich foods? Do you have difficulty digesting fatty or greasy foods? Do you experience abdominal distention after meals? Do you have abdominal pain and inflammation? If so, you may be having SIBO symptoms. �

 

Small intestinal bacterial overgrowth (SIBO) is a gastrointestinal (GI) tract health issue that can become a persistent problem if it’s not managed accordingly, especially if it’s ultimately left untreated. For many people suffering from chronic gas, bloating, constipation, and/or diarrhea, they may have also already had a diagnosis of irritable bowel syndrome (IBS). However, research studies have shown that one of the main causes of IBS may be SIBO. �

 

SIBO is a digestive health issue where there are too many bacteria in the small intestine. Bacterial overgrowth can also cause IBS. Although there are many treatment options for SIBO, one of the most important treatments for SIBO is doing everything we can to help keep SIBO from coming back. The purpose of the article above was to discuss how understanding the migrating motor complex (MMC) can help treat small intestinal bacterial overgrowth (SIBO).

 

The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�

 

Curated by Dr. Alex Jimenez �

 

References:

  • Albina, Victoria. �SIBO Begone: 5 Easy Ways to Keep Your SIBO From Coming Back.� Victoria Albina, Victoria Albina, 26 Mar. 2019, victoriaalbina.com/sibo/.
  • Brisson, John. �Migrating Motor Complex (MMC) and Digestive Health.� Fix Your Gut, Fix Your Gut, 13 Dec. 2014, www.fixyourgut.com/mmc-digestive-health/.

 


 

Additional Topic Discussion: Chronic Pain

Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �

 

 


 

Neural Zoomer Plus for Neurological Disease

Neural Zoomer Plus | El Paso, TX Chiropractor

 

Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �

 

Food Sensitivity for the IgG & IgA Immune Response

Food Sensitivity Zoomer | El Paso, TX Chiropractor

 

Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �

 

Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)

Gut Zoomer | El Paso, TX Chiropractor

Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �

 


Dunwoody Labs: Comprehensive Stool with Parasitology | El Paso, TX Chiropractor


GI-MAP: GI Microbial Assay Plus | El Paso, TX Chiropractor


 

Formulas for Methylation Support

Xymogen Formulas - El Paso, TX

XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.

 

Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.

 

Please call our office in order for us to assign a doctor consultation for immediate access.

 

If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.

xymogen el paso, tx

 

For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download

 

* All of the above XYMOGEN policies remain strictly in force.

 


 

Functional Neurology: What is the SIBO Diet?

Functional Neurology: What is the SIBO Diet?

Do you frequently eat processed foods that are bagged or boxed? Do you frequently eat fried foods? Do you have difficulty digesting foods? Do you experience constipation or inconsistent bowel movements? Do you have increased bloating or gas? If so, you may be experiencing SIBO symptoms. �

 

Small intestinal bacterial overgrowth (SIBO) is a serious health issue that happens when bacteria that generally grow in one region of the digestive system, such as the colon, grow in the small intestine, ultimately affecting the gastrointestinal (GI) tract. If left untreated, SIBO can commonly cause pain, discomfort, diarrhea, and malnutrition (because of the loss of nutrients), among other symptoms.�Proper nutrition can help decrease these harmful bacteria. �

 

Following the SIBO diet together with antibiotics can also help speed up recovery and ultimately help reduce uncomfortable symptoms. The purpose of the article below is to describe the benefits of following the SIBO diet as well as what foods you should and shouldn’t eat to help improve SIBO symptoms. �

 

Understanding the SIBO Diet

The SIBO diet involves gradually eliminating several types of foods in an attempt to help reduce inflammation in the gastrointestinal (GI) tract and help decrease bacterial overgrowth in the small intestine. In a variety of instances, the gradual elimination of sugars alone can help improve SIBO symptoms. �

 

Healthcare professionals recommend including a diet that is low in FODMAPs, or carbohydrates that can be difficult to digest and can become fermented by gut bacteria in the colon. When the digestive system is unable to break down carbs, these can sit in the gut and can cause SIBO symptoms, such as bloating and diarrhea. With SIBO, the bacterial overgrowth in the small intestine may ultimately start to ferment carbs too soon, causing a variety of symptoms. �

 

Foods You Should Eat for SIBO

As we will discuss further below, the list of foods you shouldn’t eat when you have small intestinal bacterial overgrowth (SIBO) can be considered restrictive, however, there are still several foods you can enjoy while following the SIBO diet. The SIBO diet includes foods that are high in fiber and low in sugar. �

 

Moreover, several foods can have low amounts of FODMAPs in smaller servings but these should still be limited or avoided because larger servings may increase the overall number of FODMAPs. Furthermore, several recommended types of foods for a SIBO, as well as a low FODMAP, diet include:�

 

  • oatmeal
  • unsweetened cereal (with low FODMAP grains)
  • gluten-free crackers
  • rice or gluten-free noodles
  • quinoa
  • seeds
  • peanuts
  • several types of fruits, such as strawberries, blueberries, grapes, oranges
  • leafy greens
  • broccoli (heads only, less than 3/4 cup)
  • olives
  • potatoes
  • carrots
  • pumpkin
  • spaghetti squash and summer squashes
  • eggs
  • fish
  • meat

 

Foods You Shouldn’t Eat with SIBO

According to research studies, the low FODMAP diet has been demonstrated to safely and effectively help treat irritable bowel syndrome (IBS) and its associated symptoms. Patients with IBS also commonly have SIBO. Reducing or eliminating foods that are high in FODMAPs can improve digestive health. �

 

When reducing or eliminating FODMAPs as a part of the SIBO diet, healthcare professionals suggest focusing on the main categories, including:

 

  • fructose, basic sugars frequently found in fruits and several types of vegetables as well as in honey and agave nectar,
  • fructans, a sugar substance or chemical found in many gluten products, fruits, several vegetables, and prebiotics,
  • polyols, sugar alcohol commonly utilized as a sweetener,
  • galactans, a substance or chemical found in several types of legumes, and
  • lactose, a sugar molecule frequently found in many dairy products.

 

Several types of foods which you may want to consider completely eliminating from your diet that has higher amounts of FODMAPs include:

 

  • honey
  • agave nectar
  • high-fructose corn syrup
  • soda and other types of soft beverages
  • dried fruits
  • apples
  • asparagus
  • artichokes
  • peas
  • cauliflower
  • butternut squash
  • garlic
  • onions
  • beans
  • sweetened cereals
  • grains
  • barley
  • rye
  • flavored yogurt
  • ice cream
  • sausage

 

Evidence Findings of the SIBO Diet

Healthcare professionals utilize antibiotics as the main treatment approach for small intestinal bacterial overgrowth (SIBO) symptoms. However, research studies have demonstrated that dietary changes, such as limiting sugars and lactose, may also ultimately help reduce SIBO. The SIBO diet can be utilized together with probiotics and antibiotics. A 2010 research study also determined that probiotics can also help reduce SIBO symptoms. According to the research study, drinking more water while on the SIBO diet can also help reduce pain, discomfort, and inflammation. Make sure to talk to your doctor before making any dietary modifications or implementing a new treatment option. In addition, discuss all of the benefits and risks with your doctor or dietitian. �

 

The SIBO diet is a nutrition plan which temporarily eliminates high FODMAP foods while including a variety of low-FODMAP foods to help decrease bacterial overgrowth in the small intestine. The SIBO diet generally lasts anywhere between 2 to 6 weeks. Although it has been demonstrated to be a safe and effective treatment approach, the SIBO diet treats symptoms while it may not necessarily treat the underlying condition or disease. Conventional treatment options for SIBO shouldn�t be ignored. Talk to a healthcare professional before involving diet changes to any treatment plan. It�s also fundamental to mention that you should ultimately bring FODMAPs back into your normal diet when your SIBO symptoms improve. This can help prevent healthy gut bacteria loss. If your symptoms begin to worsen after implementing the SIBO or low-FODMAP diet, make sure to seek immediate medical attention. �

 

Dr. Alex Jimenez Insights Image

Small intestinal bacterial overgrowth (SIBO) is a serious health issue which usually occurs because of an underlying chronic health issue. Several common symptoms may ultimately help determine the presence of SIBO. Additionally, if the patient has a chronic condition or disease, such as celiac disease or Crohn’s disease, they should talk to a healthcare professional to develop a treatment plan, such as the SIBO diet. SIBO, or small intestinal bacterial overgrowth is treatable. If left untreated, this gastrointestinal (GI) tract problem can also cause dehydration and malnutrition. Patients should contact a healthcare professional immediately if they suspect they have SIBO so that they can begin treatment right away. – Dr. Alex Jimenez D.C., C.C.S.T. Insight

 


 

Neurotransmitter Assessment Form

Neurotransmitter Assessment Form AE260 (1)

 

The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �

 


 

Do you frequently eat processed foods that are bagged or boxed? Do you frequently eat fried foods? Do you have difficulty digesting foods? Do you experience constipation or inconsistent bowel movements? Do you have increased bloating or gas? If so, you may be experiencing SIBO symptoms. �

 

Small intestinal bacterial overgrowth (SIBO) is a serious health issue that happens when bacteria that generally grow in one region of the digestive system, such as the colon, grow in the small intestine, ultimately affecting the gastrointestinal (GI) tract. If left untreated, SIBO can commonly cause pain, discomfort, diarrhea, and malnutrition (because of the loss of nutrients), among other symptoms. Proper nutrition can help decrease these harmful bacteria. �

 

Following the SIBO diet together with antibiotics can also help speed up recovery and ultimately help reduce uncomfortable symptoms. The purpose of the article above was to describe the benefits of following the SIBO diet as well as what foods you should and shouldn’t eat to help improve SIBO symptoms. �

 

The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�

 

Curated by Dr. Alex Jimenez �

 

References:

  • Anthony, Kiara. �SIBO Diet 101: What You Should and Shouldn’t Eat.� Edited by Natalie Butler, Healthline, Healthline, 16 Aug. 2018, www.healthline.com/health/sibo-diet.

 


 

Additional Topic Discussion: Chronic Pain

Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �

 

 


 

Neural Zoomer Plus for Neurological Disease

Neural Zoomer Plus | El Paso, TX Chiropractor

Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �

 

Food Sensitivity for the IgG & IgA Immune Response

Food Sensitivity Zoomer | El Paso, TX Chiropractor

Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �

 

Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)

Gut Zoomer | El Paso, TX Chiropractor

Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �

 


Dunwoody Labs: Comprehensive Stool with Parasitology | El Paso, TX Chiropractor


GI-MAP: GI Microbial Assay Plus | El Paso, TX Chiropractor


 

Formulas for Methylation Support

Xymogen Formulas - El Paso, TX

XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.

 

Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.

 

� Please call our office in order for us to assign a doctor consultation for immediate access.

 

If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.

xymogen el paso, tx

For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download

 

* All of the above XYMOGEN policies remain strictly in force.

 


 

Functional Neurology: What is SIBO?

Functional Neurology: What is SIBO?

Do you feel irritable, nervous, shaky, or light-headed between meals? Do you have difficulty eating large meals in the morning? Do you feel fatigued after meals? Do you have sugar and sweet cravings after meals? Do you have an increased appetite?�If so, you may be experiencing early SIBO symptoms. �

 

SIBO, or small intestinal bacterial overgrowth, is a severe health issue that ultimately affects the small intestine in the digestive system. This gastrointestinal (GI) tract condition happens when the bacteria that generally grows in several different regions of the gut begin to grow in the small intestine. SIBO can commonly cause pain, discomfort, and diarrhea, among other symptoms. It can also cause malnutrition as bacteria utilize the human body�s nutrients.�

 

What are the Symptoms of SIBO?

Small intestinal bacterial overgrowth, or SIBO, is a serious condition that includes symptoms which can commonly affect the gut. These can include:

 

  • pain or discomfort in the stomach
  • gas
  • bloating
  • constipation
  • diarrhea
  • cramps
  • indigestion
  • a general feeling of fullness
  • weight loss

 

What are the Causes of SIBO?

Small intestinal bacterial overgrowth (SIBO) is a severe health issue that is unfortunately not yet fully understood by researchers and healthcare professionals. According to research studies and clinical trials, however, this gastrointestinal, or GI, tract condition can ultimately happen when the small intestine is anatomically abnormal, due to pH changes in the small intestine, when the human body’s immune system isn’t functioning accordingly, or due to malfunctions in the muscular activity of the small intestine which can commonly cause food and bacteria to remain and not be removed from the organ. �

 

SIBO, or small intestinal bacterial overgrowth, is also commonly associated with a variety of health issues. These can involve the following, including:

 

  • a stomach bug, known as viral gastroenteritis
  • celiac disease
  • Crohn�s disease
  • low stomach acid levels, known as hypochlorhydria
  • IBS or irritable bowel syndrome
  • gastroparesis
  • portal hypertension
  • nerve damage
  • cirrhosis
  • several gastric bypass procedures
  • surgical interventions which cause strictures or adhesions

 

What are the Risk Factors of SIBO?

Moreover, researchers and healthcare professionals have determined that an underlying chronic health issue and a previous surgery or surgical intervention that affects the gastrointestinal (GI) tract can be several risk factors of SIBO. Other wellness problems which can ultimately cause SIBO include:

 

  • diabetes
  • scleroderma
  • hypothyroidism
  • Parkinson’s disease
  • HIV
  • narcotics or drugs/medications which slow down the digestive system

 

What is the Diagnosis for SIBO?

If you’ve experienced any of the SIBO symptoms mentioned above, see your doctor immediately. The doctor will ask the patient about their symptoms and medical history. The doctor will also perform a physical examination which may include palpating or gently feeling the patient’s abdomen. A qualified and experienced healthcare professional may also order additional blood, fecal, and/or any other tests to diagnose small intestinal bacterial overgrowth. �

 

A breath test is another common test utilized for the diagnosis of SIBO. Excess bacteria in the small intestine can cause the release of hydrogen and methane, two common gases which can be identified through a breath test. This test is non-invasive and can be performed in a doctor�s office. Before a breath test, the patient will need to fast overnight. During a breath test, the patient will first breathe into a tube. Then, the patient will take a specialized sweet drink provided by the doctor and they will breathe into several other tubes at regular intervals for 2 to 3 hours after taking the specialized sweet drink. �

 

If common tests for SIBO are inconclusive, the doctor may need to sample the fluid from the patient’s small intestine to see what bacteria is growing there. �

 

What is the Treatment for SIBO?

Common treatment approaches for SIBO, or small intestinal bacterial growth, can ultimately include a combination of antibiotics and diet modifications. �

 

Antibiotics

Treatment for SIBO first involves getting the bacteria in the digestive system under control. This is generally achieved by utilizing antibiotics, such as ciprofloxacin (Cipro), metronidazole (Flagyl), or rifaximin (Xifaxan). Further treatment for SIBO may also require intravenous (IV) therapy for nutrition and fluids if the serious gastrointestinal (GI) tract condition has ultimately caused malnutrition or dehydration, among a variety of other symptoms. �

 

Although antibiotics may help reduce the amount of bacteria in the small intestine, however, these will not always help address the underlying chronic health issues that caused the wellness problem in the first place. If the qualified and experienced healthcare professional determines that the patient’s SIBO is due to an underlying chronic health issue, the patient will also need to begin treatment for that wellness problem. Diet modifications may also help treat SIBO. �

 

Diet Modifications

Further research studies and clinical trials are still required to demonstrate if diet can cause small intestinal bacterial overgrowth (SIBO) but, many people with SIBO have reported feeling relief from their symptoms after diet modifications. Talk to your doctor before making any modifications to your diet. �

 

Furthermore, people with SIBO or other chronic health issues may only need to make small diet modifications to treat their symptoms. These can include:

 

  • Eating a balanced and nutritious diet
  • Consuming minimal meals more often to prevent having too much food sit in the stomach
  • Avoid eating gluten products, if you have celiac disease or any other similar chronic health issues

 

The doctor may also recommend the patient to try an elemental diet to help treat SIBO. An elemental diet replaces food and drinks with several liquid formulas throughout an extended period of time. In one small-scale research study and clinical trial, approximately 80 percent of participants with SIBO had a normal breath test result following an elemental diet for 15 days. The researchers ultimately determined that an elemental diet may be a highly effective treatment approach for SIBO. However, further evidence is still needed. Talk to your doctor before starting an elemental diet and follow their instructions. �

 

Taking probiotics may also help restore the gut bacteria. A 2010 research study and clinical trial demonstrated that probiotic treatment can be more safe and effective for SIBO than taking antibiotics. However, a 2016 review determined that further evidence for the efficiency of probiotics in SIBO treatment was ultimately inconclusive. The best treatment approach for a patient with SIBO is to follow a qualified and experienced healthcare professional’s advice. �

 

Dr. Alex Jimenez Insights Image

SIBO, or small intestinal bacterial overgrowth, is a well-known and often severe health issue that generally occurs because of an underlying chronic condition or disease. Common symptoms may ultimately determine the presence of SIBO. In addition, if the patient has a chronic health issue, such as celiac disease or Crohn’s disease, they should talk to a doctor to develop a long-term treatment plan. SIBO, or small intestinal bacterial overgrowth is treatable. If left untreated, this gastrointestinal (GI) tract problem can also cause dehydration and malnutrition. Patients should contact a doctor immediately if they suspect they have SIBO so that they can begin treatment right away. – Dr. Alex Jimenez D.C., C.C.S.T. Insight

 


 

Neurotransmitter Assessment Form

Neurotransmitter Assessment Form AE260 (1)

 

The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �

 


 

The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�

 

Curated by Dr. Alex Jimenez �

 

References:

  • Madormo, Carrie. �Everything You Should Know About Small Intestinal Bacterial Overgrowth (SIBO).� Edited by Suzanne Falck, Healthline, Healthline, 14 June 2017, www.healthline.com/health/sibo#symptoms.

 


 

Additional Topic Discussion: Chronic Pain

Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �

 

 


 

Neural Zoomer Plus for Neurological Disease

Neural Zoomer Plus | El Paso, TX Chiropractor

 

Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �

 

Food Sensitivity for the IgG & IgA Immune Response

Food Sensitivity Zoomer | El Paso, TX Chiropractor

 

Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �

 

Formulas for Methylation Support

Xymogen Formulas - El Paso, TX

 

XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.

 

Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.

 

Please call our office in order for us to assign a doctor consultation for immediate access.

 

If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.

xymogen el paso, tx

For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download

 

* All of the above XYMOGEN policies remain strictly in force.

 


 

Activating the Nrf2 Cell Defense Through Food El Paso, Texas

Activating the Nrf2 Cell Defense Through Food El Paso, Texas

The Nrf2 cell defense creates a pathway that provides protection against oxidative stress and disorders. It plays a vital role in maintaining cellular homeostasis and keeping each cell strand in check. Without the Nrf2 cell defense, oxidative stress can be excessive and directly cause or contribute to many common diseases. This includes cancer, osteoporosis, inflammatory bowel diseases, and neurodegeneration. Studies show that even oxidative stress can contribute to insulin resistance and multiple sclerosis.

2.-Oxidative-Stress

Certain foods that are beneficial to the Nrf2 cell structure, due to their antioxidative properties; can enhance the Nrf2 cell gene gradually. Researchers studied that dietary sources that contain antioxidants flavonoids, fermented food and drinks that contain lactobacilli, and sulforaphane from cruciferous vegetables; are the contributors to aid the Nrf2 cell structure. With these certain foods in a person�s diet, it can be beneficial to combating oxidative stress and preventing oxygen toxicity from producing in the bloodstream.

Food That Helps the Nrf2 Cell

Here are some of the foods that contain nutrients to help out the Nrf2 cell:

  • Fruits: Red, blue and purple berries, red and purple grapes, apples, citrus fruits and juices (oranges, grapefruits, and lemons)
  • Red wine
  • Teas: Green, white, black, and oolong
  • Chocolate
  • Vegetables: Yellow onion, scallions, kale, broccoli, celery, hot peppers, greens beans
  • Herbs: Parsley, thyme
  • Legumes: Soybeans and other soy products, chickpeas, mung beans

With these types of antioxidant foods, they can help aid the body by lowering the stress compound naturally without the usage of medications. There are ways to get the nutrients of the different food groups to support the body and activate the Nrf2 pathways. Fermented foods that contain lactobacilli can express and activate the gene pathway.

Let�s start with Lactobacillus plantarum and Lactobacillus brevis. These two are the good bacteria that are found in traditional vegetables, fruit, and fermented malt whiskey. They help the body by breaking down the food that is being consumed, absorbing the nutrients, and fighting off the harmful organisms that are causing discomfort to the gut. When these two bacteria are expressing PAD (phenolic acid derivatives) and being introduced to a caffeic acid; the results are astonishing.

Studies indicate that particular strains of lactobacilli can biotransform the caffeic acid to potently activate the Nrf2 pathways from an inactive precursor. �So let�s say that if an individual is stressed and then they eat some food. Suddenly they feel a bit better after eating, that is because of the Nrf2 pathways mixed with the enhanced lactobacilli in their food helped neutralized the stress compound in the body.

With sulforaphane in cruciferous vegetables, it can help with the Nrf2 pathways. Since cruciferous plants have natural fighting properties against cancer, they have a good source of phytonutrients and the sulforaphane combined.

Here are some of the cruciferous vegetables that can help the Nrf2 pathway in the body.

  • Arugula
  • Bok choy
  • Broccoli
  • Brussels sprouts
  • Cabbage
  • Cauliflower
  • Kale
  • Radish
  • Turnips

These vegetables are nutritious when they are eaten raw or cooked. Sulforaphane in the many cruciferous plants has been linked to many health benefits such as improving heart health and digestion. This compound has an inactive form of glucoraphanin, but when it comes in contact with myrosinase, it releases the glucosinolates. This means that when the cruciferous vegetables are either damaged, cut, chopped or chewed on, the myrosinase enzymes are activated and turning into sulforaphane.

Studies have even been shown that sulforaphane can prevent cancer cell growth by releasing antioxidants and detoxifying enzymes that protect carcinogens, which are substances that can cause cancer.

How the Nrf2 Cell Activates

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The various molecules in them can exhibit a robust activation in the Nrf2 defense system. Researchers have studied that the Nrf2 defense pathway can provide natural protection against oxidative stress and chemical toxicity through relatively small electrochemical co-factors called Nrf2 activators.

These activators actually amplify the effect of ROS (reactive oxygen species) by cycling through oxidation-reduction reactions and liberating Nrf2 in the human endothelial cells. Since the human body can get sick from stress, it is essential to eat foods that can fight off the harmful organisms. Nrf2 cells do regulate the oxidative stress by releasing itself into the body�s system. It is crucial to make sure that good, nutritious food that is beneficial in helping the Nrf2 cells by doing it naturally.

stressful-thoughts-600x338

With a person�s hectic lifestyle gets in the way, they start to feel overly stressed. The body begins to develop chronic ailments that can harm not only the outside of the body but the inside as well. When individuals go to see health care professional for any chronic diseases that they may have, they will be informed of remedies to help aid them the best way they can. Individuals can find ways to deal with the stress hormone and calm it down through functional medicine. So when the body develops oxidative stress, it will affect the organ system, the nerve system, and the neurological system.

With the Nrf2 cells, the cell structure goes towards the oxidative stress compound and put a stop to it. And with the nutritious food that is available to aid the Nrf2 cell more. When we can calm down our anxious mind through the use of functional medicine and by eating healthy, organic, whole foods; we are actually repairing the body from the inside out.

Conclusion

As stated from the beginning, the Nrf2 cell helps the body by protecting it against oxidative stress. When we add nutritious food into the collection, it is aiding the Nrf2 cells a whole lot. Since the entire body needs the nutrients from the different food groups to assist not only the Nrf2 cells but to all crucial organs that need the nutrient sources to function correctly. The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues as well as functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or chronic disorders of the musculoskeletal system. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .


References

 

Bryan, Holly K, et al. �The Nrf2 Cell Defence Pathway: Keap1-Dependent and -Independent Mechanisms of Regulation.� Biochemical Pharmacology, U.S. National Library of Medicine, 15 Mar. 2013, www.ncbi.nlm.nih.gov/pubmed/23219527.

Coyle, Daisy. �Sulforaphane: Benefits, Side Effects, and Food Sources.� Healthline, 26 Feb. 2019, www.healthline.com/nutrition/sulforaphane.

Prochaska, H J, et al. �On the Mechanisms of Induction of cancer-protective Enzymes: a Unifying Proposal.� Proceedings of the National Academy of Sciences of the United States of America, U.S. National Library of Medicine, Dec. 1985, www.ncbi.nlm.nih.gov/pubmed/3934671.

Senger, Donald R., et al. �Activation of the Nrf2 Cell Defense Pathway by Ancient Foods: Disease Prevention by Important Molecules and Microbes Lost from the Modern Western Diet.� PLOS ONE, Public Library of Science, 17 Feb. 2016, journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0148042.

Shaw, Pamela. �The Nrf2 Diet.� ALS Worldwide, 27 Jan. 2015, alsworldwide.org/care-and-support/article/the-nrf2-diet.

Su, Xuling, et al. �Anticancer Activity of Sulforaphane: The Epigenetic Mechanisms and the Nrf2 Signaling Pathway.� Oxidative Medicine and Cellular Longevity, Hindawi, 6 June 2018, www.ncbi.nlm.nih.gov/pubmed/29977456.

 

Using Integrative Methods for Hormone Testing

Using Integrative Methods for Hormone Testing

Hormone testing can now be done by using top of the line integrative methods and techniques. There are multiple reasons and benefits for an individual to complete a hormone test. These tests have the ability to help a patient understand their cycle, testosterone/ estrogen levels, why they are tired upon waking or throughout their day, and more.

Precision Analyical, Inc. has discovered a way to use scientists who have extensive experience and coupled them with the most advanced analytical methods and instruments. This allows them to achieve the best results when it comes to the dutchtest.

 

What is D.U.T.C.H?

D.U.T.C.H stands for ” Dried Urine for Comprehensive Hormones” and is comprised of multiple tests designed by Precision Analytical Inc. Dried urine samples allow scientists to see an entire day of hormones and measure multiple different aspects. There are different D.U.T.C.H tests that can be completed depending on the patient’s needs.�

  • Dutch Complete– This is a comprehensive assessment of sex and adrenal hormones and their metabolites. This test measures progesterone, androgen, estrogen metabolites, cortisol, cortisone, cortisol metabolites, creatine, DHEA-S.�
  • Dutch Sex and Hormone Metabolites– This test is focused on testing progesterone, androgen, estrogen metabolites
  • Dutch Adrenal– This is important to measure because it controls the stress hormone and the levels in the body to help with energy upon waking. This test specifically measures cortisol, cortisol metabolites, creatinine, DHEA-S
  • Dutch OATS “Organic Acid Tests”-� This test will give insights to symptoms such as mood and fatigue. This test measures 9-OHdG, melatonin.
  • Dutch Plus– This test uses 5 saliva samples to provide the up and down pattern of cortisol and cortisone throughout the day. This test adds salivary cortisol measurements of the cortisol awakening response (CAR) to the dutch complete to bring another important piece of the HPA axis into focus
  • Dutch Test Cycle Mapping– This test maps the progesterone and estrogen pattern throughout the menstrual cycle. It provides the full picture of a woman’s cycle to answer important questions for patients with month-long symptoms, infertility, and PCOS. This test is targeted to measure 9 estrogens and progesterone that are taken throughout the cycle to characterize the follicular, ovulatory, and luteal phases.�

 

dutchtest

 

How Does It Work?

One of the reasons that many practicing offices are starting to use the D.U.T.C.H tests is because they have an extremely simple sample collection. Patients will collect just 4-5 dried urine samples over a period of 24 hours. This makes transportation and collection of the sample hassle-free. The dried urine samples provide excellent results due to the fact that the collections offer a span of the entires day hormones. The time of testing looks as follows:

  • The patient obtains the first sample at approximately 5pm ( dinnertime)
  • The� second sample is to be taken around 10 pm ( bedtime)
  • This next sample is dependent upon each individual, but if the patient wakes to urinate during the night, a sample is to be collected at this time.
  • The third sample should be collected within 10 minutes of rising. It is very important that the patient does not lay in bed after waking and they collect this sample within those allotted 10 minute time frame.
  • Once the patient has collected their third sample upon rising, they should set an alarm for 2 hours, as this is when the fourth and final sample is to be collected.

As one can see above, these urine samples will be dry when sent off to the lab. Studies show that dried urine samples are stable for weeks and will give an accurate representation of the hormone levels that are being assessed. From here, the results are gone over with a team of clinicians from Precision Analytical with the doctor who ordered the test. This ensures that the best treatment protocol is created for the patient.��

 

What Is The Purpose?�

With the turn around time being just 7-10 business days, individuals can gain control fairly quickly. As mentioned, Precision Analytical uses the most advanced instruments to achieve the best results for patients. The main purpose is to create an understanding of what is going on inside the patient’s body and allows the treatment to be more specific and targeted to the individual’s needs. As Chiropractic Health Month approaches, there is no better time than now to get started!�

 

�I highly recommend the D.U.T.C.H test. Knowing and understanding your hormones and the times that they are rising and falling throughout the day opens so many doors. It allows an individual to have an understanding of why they are so tired or why they can not fall asleep and take distinctive steps towards correcting that issue, rather than shooting in the dark. In addition, it allows patients to have knowledge of what is occurring when it comes to their sex hormone metabolites. This test gives the ordering doctor a complete look at the patient’s hormones and ensures they can be confident in creating a treatment protocol. – Kenna Vaughn, Senior Health Coach

 

The scope of our information is limited to chiropractic, musculoskeletal and nervous health issues as well as functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or chronic disorders of the musculoskeletal system. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .

 

Fasting and Chronic Pain

Fasting and Chronic Pain

Chronic pain is a common health issue which affects many people in the United States. While several medical conditions, such as fibromyalgia and myofascial pain syndrome, can cause chronic pain, it may also develop due to a variety of other health issues. Research studies have found that widespread inflammation is the leading cause of chronic pain. Inflammation is a natural defense mechanism to injury, illness, or infection. But, if the inflammatory process continues for too long, it can become problematic.

Inflammation signals the immune system to heal and repair damaged tissue as well as to protect itself against bacteria and viruses. As mentioned above, however, chronic inflammation can cause a variety of health issues, including chronic pain symptoms. Healthy lifestyle modifications can help manage chronic pain, but first, let’s understand the common causes of chronic pain.

What is Acute Inflammation?

Acute inflammation, by way of instance, occurs following an injury or something as simple as a sore throat. It is a natural response with adverse effects, meaning it works locally in the region where the health issue is found. The common signs of acute inflammation include swelling, redness, warmth, pain and loss of function, as stated by the National Library of Medicine. When acute inflammation develops, the blood vessels dilate causing blood flow to increase, and white blood cells in the injured region promote recovery.

During severe inflammation, compounds called cytokines are released by the damaged tissue. The cytokines act as “emergency signals” which bring on the human body’s own immune cells, as well as hormones and numerous nutrients to repair the health issue. Additionally, hormone-like substances, known as prostaglandins, cause blood clots to heal damaged tissue, and these may also trigger fever and pain as part of the inflammatory procedure. As the damage or injury recovers, the inflammation subsides.

What is Chronic Inflammation?

Unlike acute inflammation, chronic inflammation has long-term effects. Chronic inflammation, also known as persistent inflammation, produces low-levels of inflammation throughout the human body, as demonstrated by an increase in immune system markers located in blood and cell tissues. Chronic inflammation may also cause the progression of various diseases and conditions. Elevated levels of inflammation may sometimes trigger even if there is no injury, illness, or infection, which may also cause the immune system to react.

As a result, the human body’s immune system could begin attacking healthy cells, tissues, or organs. Researchers are still trying to understand the consequences of chronic inflammation in the human body and the mechanisms involved in this natural defense process. By way of instance, chronic inflammation has been associated with a variety of health issues, such as heart disease, and stroke.

One theory suggests that when inflammation remains in the blood vessels, it can encourage the accumulation of plaque. According to the American Heart Association, or the AHA, if the immune system identifies plaque as a foreign invader, the white blood cells can attempt to wall off the plaque found in the blood flowing through the arteries. This can create a blood clot which may block the blood flow to the heart or brain, causing it to become unstable and rupture. Cancer is another health issue associated with chronic inflammation. Furthermore, according to the National Cancer Institute, DNA damage can also be caused by chronic inflammation.

Persistent, low-grade inflammation frequently doesn’t have any symptoms, but healthcare professionals can check for a C-reactive protein, or CRP, known as lipoic acid, a marker for inflammation found in the blood. Elevated levels of CRP are associated with an increased risk of cardiovascular disease. Elevated CRP levels may be found in chronic disorders like lupus or rheumatoid arthritis.

In the case of other chronic conditions, such as fibromyalgia, the nervous system over-reacts to specific stimulation, however, it’s inflammation which causes chronic pain symptoms. Subjectively, it’s almost impossible to tell the difference between the chronic pain caused by an oversensitive nervous system and the chronic pain caused by widespread inflammation. Apart from searching for clues in the bloodstream, a person’s nutrition, lifestyle habits, and environmental exposures, can also promote chronic inflammation.

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Inflammation is the immune system’s natural defense mechanism against injury, illness, or infection. While this inflammatory response can help heal and repair tissues, chronic, widespread inflammation can cause a variety of health issues, including chronic pain symptoms. A balanced nutrition, including a variety of diets and fasting, can help reduce inflammation. Fasting, also known as caloric restriction, promotes cell apoptosis and mitochondrial recovery. The fasting mimicking diet, which is a part of the longevity diet plan, is a dietary program which “tricks” the human body into a fasting state to experience the benefits of traditional fasting. Before following any of the diets described in this article, make sure to consult a doctor.

Dr. Alex Jimenez D.C., C.C.S.T. Insight

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Nutrition, Diets, Fasting and Chronic Pain

Anti-inflammatory diets mainly consist of eating fresh fruits and vegetables, fish, and fats. The Mediterranean diet plan, by way of instance, is an anti-inflammatory diet which promotes eating moderate amounts of nuts, ingesting very little meat, and drinking wine. Anti-inflammatory food parts, such as omega-3 fatty acids, protect the human body against the damage brought on by inflammation.

An anti-inflammatory diet also involves staying away from foods which could promote inflammation. It is ideal to decrease the amount of foods you eat which are high in trans and saturated fats, such as meats. Additionally, an anti-inflammatory diet limits the consumption of refined carbohydrates and foods, such as bread and rice. These also promote cutting back on the utilization of margarine and oils that are packed with omega-6 fatty acids, such as sunflower, safflower and corn oils.

Fasting, or caloric restriction, has long been known to decrease oxidative stress and slow down the mechanisms of aging in various organisms. The effects of fasting involve programmed cell death, or apoptosis, transcription, mobile energy efficiency, mitochondrial biogenesis, antioxidant mechanisms, and circadian rhythm. Fasting also contributes to mitochondrial autophagy, known as mitophagy, where genes in the mitochondria are stimulated to undergo apoptosis, which promotes mitochondrial recovery.

Intermittent fasting can help you fight inflammation, improve digestion, and boost your longevity. The human body is designed to be able to survive for extended periods of time without food. Research studies have demonstrated that intermittent fasting can have positive changes in the overall composition of your gut microbiota. Moreover, intermittent fasting can reduce insulin resistance while increasing the immune system response. Finally, intermittent fasting can promote the production of a substance, known as ?-hydroxybutyrate, that blocks a portion of the immune system involved in inflammatory ailments as well as substantially reducing the production of inflammatory markers, such as cytokines and the C-reactive protein, or CRP, previously mentioned above.

The Longevity Diet Plan, presented in the book by Dr. Valter Longo, eliminates the consumption of processed foods which can cause inflammation, promoting well-being and longevity. This unique dietary program, unlike most traditional diets, doesn’t promote weight loss. Although you may experience weight reduction, the emphasis of this unique dietary program is on eating healthier. The Longevity Diet Plan has been demonstrated to help activate stem cell-based renewal, reduce abdominal fat, and prevent age-related bone and muscle loss, as well as build resistance to developing cardiovascular disease, Alzheimer’s disease, diabetes, and cancer.

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The fasting mimicking diet, or FMD, allows you to experience the benefits of traditional fasting without depriving your body of food. The main difference of the FMD is that instead of completely eliminating all food for several days or even weeks, you only restrict your calorie intake for five days out of the month. The FMD can be practiced once a month to help promote overall health and wellness.

While anyone can follow the FMD on their own, the ProLon� fasting mimicking diet offers a 5-day meal program which has been individually packed and labeled for each day, that serves the foods you need for the FMD in precise quantities and combinations. The meal program is made up of ready-to-eat or easy-to-prepare, plant-based foods, including bars, soups, snacks, supplements, a drink concentrate, and teas. Before starting the ProLon� fasting mimicking diet, 5-day meal program, or any of the lifestyle modifications described above, please make sure to talk to a healthcare professional to find out which chronic pain treatment is right for you.

The scope of our information is limited to chiropractic, spinal health issues, and functional medicine articles, topics, and discussions. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .

Curated by Dr. Alex Jimenez

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Additional Topic Discussion: Acute Back Pain

Back pain is one of the most prevalent causes of disability and missed days at work worldwide. Back pain attributes to the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience back pain at least once throughout their life. Your spine is a complex structure made up of bones, joints, ligaments, and muscles, among other soft tissues. Injuries and/or aggravated conditions, such as herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief.

Xymogen Formulas - El Paso, TX

XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.

Proudly, Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.

Please call our office in order for us to assign a doctor consultation for immediate access.

If you are a patient of Injury Medical & Chiropractic Clinic, you may inquire about XYMOGEN by calling 915-850-0900.

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For your convenience and review of the XYMOGEN products please review the following link.*XYMOGEN-Catalog-Download

* All the above XYMOGEN policies remain strictly in force.

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What is the Longevity Diet Plan?

What is the Longevity Diet Plan?

Adhering to a specific diet to maintain proper nutrition can sometimes make eating stressful. Natural lifestyle modifications are the key to changing your eating habits and this can help you live a longer, healthier life. The Longevity Diet Plan, created by Dr. Valter Longo, is a selection of practical eating guidelines which focuses on changing your eating patterns to achieve overall health and wellness.

The Rules of The Longevity Diet Plan

By merely following the nutritional tips below, you can overhaul your current diet plan and start eating healthier without all the stress of a traditional diet. The Longevity Diet Plan eliminates the consumption of processed foods that can cause a variety of health issues and boosts the consumption of nutrients that promote longevity. This unique dietary program shares the results of approximately 25 years of research studies all on a simple solution which can help people experience overall well-being through proper nutrition.

However, unlike most traditional diets, the Longevity Diet Plan doesn’t promote weight loss. Although you may experience weight reduction, the emphasis of this unique dietary program is on eating healthier. The Longevity Diet Plan has been demonstrated to help you activate stem cell-based renewal, lose weight and reduce abdominal fat, prevent age-related bone and muscle loss, build resistance to developing cardiovascular disease, Alzheimer’s disease, diabetes, and cancer, as well as extend longevity. Below, we will summarize the 8 most common nutritional tips of the Longevity Diet Plan which can ultimately help make your life longer and healthier.

Dr Jimenez White Coat

The Longevity Diet Plan is a unique dietary program designed by Dr. Valter Longo to promote overall health, wellness, and longevity. Through simple lifestyle modifications, people can change their eating habits and take advantage of the many health benefits of this dietary program. By following a pescatarian diet and following the ProLon� Fasting Mimicking Diet, among the other nutritional tips described below, people can live longer and healthier lives. Traditional diets can often be difficult and stressful to follow, however, the Longevity Diet Plan is a practical and unique dietary program which can be suitable for many people.

Dr. Alex Jimenez D.C., C.C.S.T. Insight

8 Nutritional Tips of the Longevity Diet Plan

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Follow a Pescatarian Diet

As a part of the Longevity Diet Plan, follow a pescatarian diet, which is almost 100 percent plant and fish-based. Also, make sure to limit fish consumption to two or three servings every week, avoiding fish with higher mercury content, such as tuna, swordfish, mackerel, and halibut. If you’re over 65 and you begin to experience reduced muscle mass, strength, and fat, add more fish into your diet alongside other animal-based foods, including eggs and specific cheeses, such as feta or pecorino, and yogurt made from goat’s milk.

Don’t Eat Too Much Protein

According to the Longevity Diet Plan, we should eat 0.31 to 0.36 grams of protein per pound of body fat every day. If you weigh 130lbs, you should eat about 40 to 47 grams of protein per day, or an equivalent of 1.5 filets of salmon, 1 cup of chickpeas or 2 1/2 cups of lentils, of which 30 grams should be consumed in one meal. If you weigh 200 to 220lbs, you should eat about 60 to 70 grams of protein per day, or an equivalent of two fillets of salmon, 3 1/2 cups of lentils or 1 1/2 cups of chickpeas. Protein consumption should be increased after age 65. For the majority of us, a 10 to 20 percent increase, or 5 to 10 grams more each day, is enough. Finally, the Longevity Diet is free of animal proteins like red meat, white meat, and poultry, with the exception of animal proteins in fish. This unique dietary program instead is comparatively high in vegetable proteins like legumes and nuts to optimize health and wellness.

Increase Good Fats and Complex Carbohydrates

As a part of the Longevity Diet Plan, you should eat higher amounts of polyunsaturated fats, such as those found in salmon, almonds, walnuts, and olive oil, while you should eat lower amounts of saturated, hydrogenated, and trans fats. Likewise, as a part of the Longevity Diet Plan, you should also eat complex carbohydrates, such as those found in whole wheat bread, legumes, and vegetables. Make sure to limit eating pasta, rice, bread, fruit, and fruit juices, which can be converted to sugars by the time they reach your gut.

Take Dietary Supplements

The human body needs proteins, essential fatty acids like omega-3 and omega-6, vitamins, minerals, and even sugars to function correctly. Whenever your intake of certain nutrients becomes too low, the repair, replacement, and defense methods of the human body can slow down or stop, allowing fungi, bacteria, and viruses to cause damage which can lead to a variety of health issues. Take vitamin and mineral dietary supplements, especially for omega-3, as recommended by your healthcare professional.

Eat Various Foods from your Ancestry

To take in all of the necessary nutrients you need, you have to eat a wide variety of foods, but it’s best to choose foods that were common on your parents’, grandparents’, and great-grandparents’ table. By way of instance, in many northern European countries where milk has been generally consumed, lactose intolerance is relatively rare, whereas lactose intolerance is quite common in southern European and Asian countries, where milk was not historically part of the conventional diet of adults. If a person of Japanese ancestry residing in the United States suddenly decides to begin drinking milk, which was probably rarely served in their grandparents’ dining table, they will probably start feeling sick. The most common problems in these cases are intolerances or autoimmunities, such as the response to gluten-rich foods like bread and pasta seen in people with celiac disease. Although further evidence is needed, it is possible that food intolerances could be related to many autoimmune disorders, including diabetes, colitis, and Crohn’s disease.

Eat Two Meals a Day and a Snack

According to the Longevity Diet Plan, it is ideal to eat breakfast and one major meal plus a nourishing low-calorie, low-sugar snack every day. While for some people it may be recommended to eat three meals and a snack every day. Many nutritional guidelines recommend that we should eat five to six meals every day. When people are advised to eat frequently, it can often become difficult for them to regulate their calorie intake. Over the last twenty years, approximately 70 percent of the population in the United States is considered to be overweight or obese. It’s much more difficult to overeat on the Longevity Diet Plan if you eat only two and a half meals every day. It would take massive portions of legumes, vegetables, and fish to reach the amount that would lead to weight gain. The high nourishment of the meals, plus the amount of the meal, sends a signal to your stomach and your brain that you have had enough food. This one major meal system may sometimes have to be broken down into two meals to avoid digestion issues. Adults and older people prone to weight loss should eat three meals a day. For people trying to lose weight as well as for people who are overweight or obese, the best nutritional advice would be to eat breakfast daily; have dinner or lunch, but not both, and substitute for the missed meal with one snack containing fewer than 100 calories and no more than 3 to 5 g of sugar. Which meal you skip depends upon your lifestyle, however, it’s not recommended to skip breakfast due to its adverse health issues. The benefit of skipping lunch is more free time and energy. But, there is a drawback for eating a large dinner, particularly for people who suffer from acid reflux or sleeping problems. The drawback for skipping dinner, however, is that it may eliminate the social meal of their day.

Eat Within a 12-Hour Window Every Day

Another common eating habit adopted by many centenarians is time-restricted eating or limiting all meals and snacks within a 12-hour window every day. The efficiency of this method was demonstrated in both human and animal research studies. Generally, you would eat breakfast at 8 a.m. and then eat dinner by 8 p.m.. A briefer eating window of ten hours or less can be even better for weight loss, but it’s considerably harder to maintain and it might increase the risk of developing side effects, such as gallstones and even potentially increasing the chance of developing cardiovascular disease. You should not eat three to four hours before sleeping.

Follow the ProLon� Fasting Mimicking Diet

Healthy people under the age of 65 should follow the ProLon� Fasting Mimicking Diet, 5-day meal program at least twice every year. The FMD is one of the key principles promoted by the Longevity Diet Plan. The fasting mimicking diet offers the same health benefits of fasting without actually fasting. By eating 800 to 1,100 calories in precise quantities and combinations of foods which have been individually packed and labeled for each day, you can “trick” the human body into a fasting state. Through various research studies, Dr. Valter Longo discovered that by depriving the body of food in this manner, our cells begin breaking down and regenerating our internal tissues, through a process known as autophagy, killing and replacing, or regenerating, damaged cells. Additionally, fasting can reverse various health issues, destroy cancer cells and significantly reduce the possibility of developing Alzheimer’s disease.

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With the Longevity Diet Plan presented in the book by Dr. Valter Longo, you’ll eat better, feel better and, although it’s not designed as a weight loss plan, you may even shed a few pounds. You’re not going to have to consider complex food rules and make difficult choices with this unique dietary program. Once you get the hang of these lifestyle modifications, you’ll be able to improve your overall health and wellness as well as your longevity. The scope of our information is limited to chiropractic, spinal health issues, and functional medicine topics. To further discuss the subject matter, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .

Curated by Dr. Alex Jimenez

Green Call Now Button H .png

Additional Topic Discussion: Acute Back Pain

Back pain is one of the most prevalent causes of disability and missed days at work worldwide. Back pain attributes to the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience back pain at least once throughout their life. Your spine is a complex structure made up of bones, joints, ligaments, and muscles, among other soft tissues. Injuries and/or aggravated conditions, such as herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief.

Xymogen Formulas - El Paso, TX

XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.

Proudly, Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.

Please call our office in order for us to assign a doctor consultation for immediate access.

If you are a patient of Injury Medical & Chiropractic Clinic, you may inquire about XYMOGEN by calling 915-850-0900.

xymogen el paso, tx

For your convenience and review of the XYMOGEN products please review the following link.*XYMOGEN-Catalog-Download

* All the above XYMOGEN policies remain strictly in force.

***

Fasting Mimicking Diet Explained

Fasting Mimicking Diet Explained

Understanding the ProLon� Fasting Mimicking Diet

Fasting is associated with numerous health benefits; from weight loss to longevity. There are many different types of fasting methods, such as intermittent fasting. The fasting mimicking diet allows you to experience the benefits of traditional fasting without depriving your body of food. The main difference of the FMD is that instead of completely eliminating all food for several days or even weeks, you only restrict your calorie intake for five days out of the month. The FMD can be practiced once a month to promote well-being.

While anyone can follow the FMD on their own, the ProLon� fasting mimicking diet offers a 5-day meal program which has been individually packed and labeled for each day and it serves the foods you need for the FMD in precise quantities and combinations. The meal program is made up of ready-to-eat or easy-to-prepare, plant-based foods, including bars, soups, snacks, supplements, a drink concentrate, and teas. The products are scientifically formulated and great tasting. Before starting the ProLon� fasting mimicking diet, 5-day meal program, please make sure to talk to a healthcare professional to find out if the FMD is right for you. The purpose of the research study below is to demonstrate the molecular mechanisms and clinical applications of fasting in the FMD.

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Fasting: Molecular Mechanisms and Clinical Applications

Fasting has been practiced for millennia, but only recently studies have shed light on its role in adaptive cellular responses that reduce oxidative damage and inflammation, optimize energy metabolism and bolster cellular protection. In lower eukaryotes, chronic fasting extends longevity in part by reprogramming metabolic and stress resistance pathways. In rodents intermittent or periodic fasting protects against diabetes, cancers, heart disease and neurodegeneration, while in humans it helps reduce obesity, hypertension, asthma and rheumatoid arthritis. Thus, fasting has the potential to delay aging and help prevent and treat diseases while minimizing the side effects caused by chronic dietary interventions.

Introduction

In humans, fasting is achieved by ingesting no or minimal amounts of food and caloric beverages for periods that typically range from 12 hours to three weeks. Many religious groups incorporate periods of fasting into their rituals including Muslims who fast from dawn until dusk during the month of Ramadan, and Christians, Jews, Buddhists and Hindus who traditionally fast on designated days of the week or calendar year. In many clinics, patients are now monitored by physicians while undergoing water only or very low calorie (less than 200 kcal/day) fasting periods lasting from 1 week or longer for weight management, and for disease prevention and treatment. Fasting is distinct from caloric restriction (CR) in which the daily caloric intake is reduced chronically by 20�40%, but meal frequency is maintained. Starvation is instead a chronic nutritional insufficiency that is commonly used as a substitute for the word fasting, particularly in lower eukaryotes, but that is also used to define extreme forms of fasting, which can result in degeneration and death. We now know that fasting results in ketogenesis, promotes potent changes in metabolic pathways and cellular processes such as stress resistance, lipolysis and autophagy, and can have medical applications that in some cases are as effective as those of approved drugs such as the dampening of seizures and seizure-associated brain damage and the amelioration of rheumatoid arthritis (Bruce-Keller et al., 1999; Hartman et al., 2012; Muller et al., 2001). As detailed in the remainder of this article, findings from well-controlled investigations in experimental animals, and emerging findings from human studies, indicate that different forms of fasting may provide effective strategies to reduce weight, delay aging, and optimize health. Here we review the fascinating and potent effects of different forms of fasting including intermittent fasting (IF, including alternate day fasting, or twice weekly fasting, for example) and periodic fasting (PF) lasting several days or longer every 2 or more weeks. We focus on fasting and minimize the discussion of CR, a topic reviewed elsewhere (Fontana et al., 2010; Masoro, 2005).

Lessons from Simple Organisms

The remarkable effects of the typical 20�40% CR on aging and diseases in mice and rats are often viewed as responses evolved in mammals to adapt to periods of limited availability of food (Fontana and Klein, 2007; Fontana et al., 2010; Masoro, 2005; Weindruch and Walford, 1988). However, the cellular and molecular mechanisms responsible for the protective effects of CR have likely evolved billions of years earlier in prokaryotes attempting to survive in an environment largely or completely devoid of energy sources while avoiding age-dependent damage that could compromise fitness. In fact, E. coli switched from a nutrient rich broth to a calorie-free medium survive 4 times longer, an effect reversed by the addition of various nutrients but not acetate, a carbon source associated with starvation conditions (Figure 1A) (Gonidakis et al., 2010). The effect of rich medium but not acetate in reducing longevity raises the possibility that a ketone body-like carbon source such as acetate may be part of an �alternate metabolic program� that evolved billions of years ago in microorganisms and that now allows mammals to survive during periods of food deprivation by obtaining much of the energy by catabolizing fatty acids and ketone bodies including acetoacetate and ?-hydroxybutyrate (Cahill, 2006).

In the yeast S. cerevisiae, switching cells from standard growth medium to water also causes a consistent 2-fold chronological lifespan extension as well as a major increase in the resistance to multiple stresses (Figure 1B) (Longo et al., 1997; Longo et al., 2012). The mechanisms of food deprivation-dependent lifespan extension involve the down-regulation of the amino acid response Tor-S6K (Sch9) pathway as well as of the glucose responsive Ras-adenylate cyclase-PKA pathway resulting in the activation of the serine/threonine kinase Rim15, a key enzyme coordinating the protective responses (Fontana et al., 2010). The inactivation of Tor-S6K, Ras-AC-PKA and activation of Rim15 result in increased transcription of genes including superoxide dismutases and heat shock proteins controlled by stress responsive transcription factors Msn2, Msn4 and Gis1, required for the majority of the protective effects caused by food deprivation (Wei et al., 2008). Notably, when switched to food deprivation conditions, both bacteria and yeast enter a hypometabolic mode that allows them to minimize the use of reserve carbon sources and can also accumulate high levels of the ketone body-like acetic acid, analogously to mammals.

Another major model organism in which fasting extends lifespan is the nematode C. elegans. Food deprivation conditions achieved by feeding worms little or no bacteria, lead to a major increase in lifespan (Figure 1C) (Kaeberlein et al., 2006; Lee et al., 2006), which requires AMPK as well as the stress resistance transcription factor DAF-16, similarly to the role of transcription factors Msn2/4 and Gis1 in yeast and FOXOs in flies and mammals (Greer et al., 2007). Intermittent food deprivation also extends lifespan in C. elegans by a mechanism involving the small GTPase RHEB-1 (Honjoh et al., 2009).

In flies, most studies indicate that intermittent food deprivation does not affect lifespan (Grandison et al., 2009). However, food reduction or food dilution have been consistently shown to extend Drosophila longevity (Piper and Partridge, 2007) suggesting that flies can benefit from dietary restriction but may be sensitive to even short starvation periods.

Together these results indicate that food deprivation can result in pro-longevity effects in a wide variety of organisms, but also underline that different organisms have different responses to fasting.

Adaptive Responses to Fasting in Mammals

In most mammals, the liver serves as the main reservoir of glucose, which is stored in the form of glycogen. In humans, depending upon their level of physical activity, 12 to 24 hours of fasting typically results in a 20% or greater decrease in serum glucose and depletion of the hepatic glycogen, accompanied by a switch to a metabolic mode in which non-hepatic glucose, fat-derived ketone bodies and free fatty acids are used as energy sources (Figures 2 and 3). Whereas most tissues can utilize fatty acids for energy, during prolonged periods of fasting, the brain relies on the ketone bodies ?-hydroxybutyrate and acetoacetate in addition to glucose for energy consumption (Figure 3B). Ketone bodies are produced in hepatocytes from the acetyl-CoA generated from ? oxidation of fatty acids released into the bloodstream by adipocytes, and also by the conversion of ketogenic amino acids. After hepatic glycogen depletion, ketone bodies, fat-derived glycerol, and amino acids account for the gluconeogenesis-dependent generation of approximately 80 grams/day of glucose, which is mostly utilized by the brain. Depending on body weight and composition, the ketone bodies, free fatty acids and gluconeogenesis allow the majority of human beings to survive 30 or more days in the absence of any food and allow certain species, such as king penguins, to survive for over 5 months without food (Eichhorn et al., 2011) (Figure 3C). In humans, during prolonged fasting, the plasma levels of 3-?-hydroxybutyrate are about 5 times those of free fatty acids and acetoacetic acid (Figure 3A and 3B). The brain and other organs utilize ketone bodies in a process termed ketolysis, in which acetoacetic acid and 3-?- hydroxybutyrate are converted into acetoacetyl-CoA and then acetyl-CoA. These metabolic adaptations to fasting in mammals are reminiscent of those described earlier for E. coli and yeast, in which acetic acid accumulates in response to food deprivation (Gonidakis et al., 2010; Longo et al., 2012). In yeast, glucose, acetic acid and ethanol, but not glycerol which is also generated during fasting from the breakdown of fats, accelerate aging (Fabrizio et al., 2005; Wei et al., 2009). Thus, glycerol functions as a carbon source that does not activate the pro-aging nutrient signaling pathways but can be catabolized by cells. It will be important to understand how the different carbon sources generated during fasting affect cellular protection and aging. and to determine whether glycerol, specific ketone bodies or fatty acids can provide nourishment while reducing cellular aging in mammals, a possibility suggested by beneficial effects of a dietary ketone precursor in a mouse model of Alzheimer�s disease (Kashiwaya et al., 2012). It will also be important to study, in various model organisms and humans, how high intake of specific types of fats (medium- vs. long- chain fatty acids, etc.) in substitution of carbohydrates and proteins influences gluconeogenesis and glucose levels as well as aging and diseases.

Fasting and the Brain

In mammals, severe CR/food deprivation results in a decrease in the size of most organs except the brain, and the testicles in male mice (Weindruch and Sohal, 1997). From an evolutionary perspective this implies that maintenance of a high level of cognitive function under conditions of food scarcity is of preeminent importance. Indeed, a highly conserved behavioral trait of all mammals is to be active when hungry and sedentary when satiated. In rodents, alternating days of normal feeding and fasting (IF) can enhance brain function as indicated by improvements in performance on behavioral tests of sensory and motor function (Singh et al., 2012) and learning and memory (Fontan-Lozano et al., 2007). The behavioral responses to IF are associated with increased synaptic plasticity and increased production of new neurons from neural stem cells (Lee et al., 2002).

Particularly interesting with regards to adaptive responses of the brain to limited food availability during human evolution is brain-derived neurotrophic factor (BDNF). The genes encoding BDNF and its receptor TrkB appeared in genomes relatively recently as they are present in vertebrates, but absent from worms, flies and lower species (Chao, 2000). The prominent roles of BDNF in the regulation of energy intake and expenditure in mammals is highlighted by the fact that the receptors for both BDNF and insulin are coupled to the highly conserved PI3 kinase � Akt, and MAP kinase signaling pathways (Figure 4). Studies of rats and mice have shown that running wheel exercise and IF increase BDNF expression in several regions of the brain, and that BDNF in part mediates exercise- and IF-induced enhancement of synaptic plasticity, neurogenesis and neuronal resistance to injury and disease (see sections on fasting and neurodegeneration below). BDNF signaling in the brain may also mediate behavioral and metabolic responses to fasting and exercise including regulation of appetite, activity levels, peripheral glucose metabolism and autonomic control of the cardiovascular and gastrointestinal systems (Mattson, 2012a, b; Rothman et al., 2012).

Hunger is an adaptive response to food deprivation that involves sensory, cognitive and neuroendocrine changes which motivate and enable food seeking behaviors. It has been proposed that hunger-related neuronal networks, neuropeptides and hormones play pivotal roles in the beneficial effects of energy restriction on aging and disease susceptibility. As evidence, when mice in which the hypothalamic �hunger peptide� NPY is selectively ablated are maintained on a CR diet, the ability of CR to suppress tumor growth is abolished (Shi et al., 2012). The latter study further showed that the ability of CR to elevate circulating adiponectin levels was also compromised in NPY-deficient mice, suggesting a key role for the central hunger response in peripheral endocrine adaptations to energy restriction. Adiponectin levels increase dramatically in response to fasting; and data suggest roles for adiponectin in the beneficial effects of IF on the cardiovascular system (Wan et al., 2010). The hunger response may also improve immune function during aging as ghrelin-deficient mice exhibit accelerated thymic involution during aging, and treatment of middle age mice with ghrelin increases thymocyte numbers and improves the functional diversity of peripheral T cell subsets (Peng et al., 2012). In addition to its actions on the hypothalamus and peripheral endocrine cells, fasting may increase neuronal network activity in brain regions involved in cognition, resulting in the production of BDNF, enhanced synaptic plasticity and improved stress tolerance (Rothman et al., 2012). Thus, hunger may be a critical factor involved in widespread central and peripheral adaptive responses to the challenge of food deprivation for extended time periods.

Fasting, Aging, and Disease in Rodent Models

Different Fasting Methods and Aging

The major differences between IF and PF in mice are the length and the frequency of the fast cycles. IF cycles usually last 24 hours and are one to a few days apart, whereas PF cycles last 2 or more days and are at least 1 week apart, which is necessary for mice to regain their normal weight. One difference in the molecular changes caused by different fasting regimes is the effect on a variety of growth factors and metabolic markers, with IF causing more frequent but less pronounced changes than PF. It will be important to determine how the frequency of specific changes such as the lowering of IGF-1 and glucose affect cellular protection, diseases and longevity. The most extensively investigated IF method in animal studies of aging has been alternate day fasting (food is withdrawn for 24 hours on alternate days, with water provided ad libitum) (Varady and Hellerstein, 2007). The magnitude of the effects of alternate day fasting on longevity in rodents depends upon the species and age at regimen initiation, and can range from a negative effect to as much as an 80% lifespan extension (Arum et al., 2009; Goodrick et al., 1990). IF every other day extended the lifespan of rats more than fasting every 3rd or 4th day (Carlson and Hoelzel, 1946). Fasting for 24 hours twice weekly throughout adult life resulted in a significant increase in lifespan of black-hooded rats (Kendrick, 1973). In rats, the combination of alternate day fasting and treadmill exercise resulted in greater maintenance of muscle mass than did IF or exercise alone (Sakamoto and Grunewald, 1987). Interestingly, when rats were maintained for 10 weeks on a PF diet in which they fasted 3 consecutive days each week, they were less prone to hypoglycemia during 2 hours of strenuous swimming exercise as a result of their accumulation of larger intramuscular stores of glycogen and triglycerides (Favier and Koubi, 1988). Several major physiological responses to fasting are similar to those caused by regular aerobic exercise including increased insulin sensitivity and cellular stress resistance, reduced resting blood pressure and heart rate, and increased heart rate variability as a result of increased parasympathetic tone (Figure 2) (Anson et al., 2003; Mager et al., 2006; Wan et al., 2003). Emerging findings suggest that exercise and IF retard aging and some age-related diseases by shared mechanisms involving improved cellular stress adaptation (Stranahan and Mattson, 2012). However, in two different mouse genetic backgrounds, IF did not extend mean lifespan and even reduced lifespan when initiated at 10 months (Goodrick et al., 1990). When initiated at 1.5 months, IF either increased longevity or had no effect (Figure 1D) (Goodrick et al., 1990). These results in rodents point to conserved effects of fasting on lifespan, but also to the need for a much better understanding of the type of fasting that can maximize its longevity effects and the mechanisms responsible for the detrimental effects that may be counterbalancing its anti-aging effects. For example, one possibility is that fasting may be consistently protective in young and middle aged laboratory rodents that are either gaining or maintaining a body weight, but may be detrimental in older animals that, similarly to humans, begin to lose weight prior to their death. Notably, whereas bacteria, yeast and humans can survive for several weeks or more without nutrients, most strains of mice are unable to survive more than 3 days without food. The age-dependent weight loss may make this sensitivity to long periods of fasting worse.

Fasting and Cancer

Fasting can have positive effects in cancer prevention and treatment. In mice, alternate day fasting caused a major reduction in the incidence of lymphomas (Descamps et al., 2005) and fasting for 1 day per week delayed spontaneous tumorigenesis in p53-deficient mice (Berrigan et al., 2002). However, the major decrease in glucose, insulin and IGF-1 caused by fasting, which is accompanied by cell death and/or atrophy in a wide range of tissues and organs including the liver and kidneys, is followed by a period of abnormally high cellular proliferation in these tissues driven in part by the replenishment of growth factors during refeeding. When combined with carcinogens during refeeding, this increased proliferative activity can actually increase carcinogenesis and/or pre-cancerous lesions in tissues including liver and colon (Tessitore et al., 1996). Although these studies underline the need for an in depth understanding of its mechanisms of action, fasting is expected to have cancer preventive effects as indicated by the studies above and by the findings that multiple cycles of periodic fasting can be as effective as toxic chemotherapy in the treatment of some cancers in mice (Lee et al., 2012).

In the treatment of cancer, fasting has been shown to have more consistent and positive effects. PF for 2�3 days was shown to protect mice from a variety of chemotherapy drugs, an effect called differential stress resistance (DSR) to reflect the inability of cancer cells to become protected based on the role of oncogenes in negatively regulating stress resistance, thus rendering cancer cells, by definition, unable to become protected in response to fasting conditions (Figure 5) (Raffaghello et al., 2008). PF also causes a major sensitization of various cancer cells to chemo-treatment, since it fosters an extreme environment in combination with the stress conditions caused by chemotherapy. In contrast to the protected state entered by normal cells during fasting, cancer cells are unable to adapt, a phenomenon called differential stress sensitization (DSS), based on the notion that most mutations are deleterious and that the many mutations accumulated in cancer cells promote growth under standard conditions but render them much less effective in adapting to extreme environments (Lee et al., 2012). In mouse models of metastatic tumors, combinations of fasting and chemotherapy that cause DSR and DSS, result in 20 to 60% cancer-free survival compared to the same levels of chemotherapy or fasting alone, which are not sufficient to cause any cancer-free survival (Lee et al., 2012; Shi et al., 2012). Thus, the idea that cancer could be treated with weeks of fasting alone, made popular decades ago, may be only partially true, at least for some type of cancers, but is expected to be ineffective for other types of cancers. The efficacy of long-term fasting alone (2 weeks or longer) in cancer treatment will need to be tested in carefully designed clinical trials in which side effects including malnourishment and possibly a weakened immune system and increased susceptibility to certain infections are carefully monitored. By contrast, animal data from multiple laboratories indicate that the combination of fasting cycles with chemotherapy is highly and consistently effective in enhancing chemotherapeutic index and has high translation potential. A number of ongoing trials should soon begin to determine the efficacy of fasting in enhancing cancer treatment in the clinic.

Fasting and Neurodegeneration

Compared to ad libitum-fed controls, rats and mice maintained on an IF diet exhibit less neuronal dysfunction and degeneration, and fewer clinical symptoms in models of Alzheimer�s disease (AD), Parkinson�s disease (PD) and Huntington�s disease (HD). These models include transgenic mice expressing mutant human genes that cause dominantly inherited AD (amyloid precursor protein and presenilin-1) and frontotemporal lobe dementia (Tau) (Halagappa et al., 2007), PD (?-synuclein) (Griffioen et al., 2012) and HD (huntingtin) (Duan et al., 2003), as well as neurotoxin-based models pertinent to AD, PD and HD (Bruce-Keller et al., 1999; Duan and Mattson, 1999). Animals on an IF diet also fare better than ad libitum-fed controls after acute injury including severe epileptic seizures, stroke, and traumatic brain and spinal cord injuries (Arumugam et al., 2010; Bruce-Keller et al., 1999; Plunet et al., 2008).

Several interrelated cellular mechanisms contribute to the beneficial effects of IF on the nervous system including reduced accumulation of oxidatively damaged molecules, improved cellular bioenergetics, enhanced neurotrophic factor signaling, and reduced inflammation (Mattson, 2012a). The latter neuroprotective mechanisms are supported by studies showing that IF diets boost levels of antioxidant defenses, neurotrophic factors (BDNF and FGF2) and protein chaperones (HSP-70 and GRP-78), and reduce levels of pro- inflammatory cytokines (TNF?, IL-1? and IL-6) (Figure 4) (Arumugam et al., 2010). IF may also promote restoration of damaged nerve cell circuits by stimulating synapse formation and the production of new neurons from neural stem cells (neurogenesis) (Lee et al., 2002). Interestingly, while beneficial in models of most neurodegenerative conditions, there is evidence that fasting can hasten neurodegeneration in some models of inherited amyotrophic lateral sclerosis, perhaps because the motor neurons affected in those models are unable to respond adaptively to the moderate stress imposed by fasting (Mattson et al., 2007; Pedersen and Mattson, 1999).

Fasting and the Metabolic Syndrome

Metabolic syndrome (MS), defined as abdominal adiposity, combined with insulin resistance, elevated triglycerides and/or hypertension, greatly increases the risk of cardiovascular disease, diabetes, stroke and AD. Rats and mice maintained under the usual ad libitum feeding condition develop an MS-like phenotype as they age. MS can also be induced in younger animals by feeding them a diet high in fat and simple sugars (Martin et al., 2010). IF can prevent and reverse all aspects of the MS in rodents: abdominal fat, inflammation and blood pressure are reduced, insulin sensitivity is increased, and the functional capacities of the nervous, neuromuscular and cardiovascular systems are improved (Castello et al., 2010; Wan et al., 2003). Hyperglycemia is ameliorated by IF in rodent models of diabetes (Pedersen et al., 1999) and the heart is protected against ischemic injury in myocardial infarction models (Ahmet et al., 2005). A protective effect of fasting against ischemic renal and liver injury occurs rapidly, with 1 � 3 days of fasting improving functional outcome and reducing tissue injury and mortality (Mitchell et al., 2010). Six days on a diet missing just a single essential amino acid such as tryptophan can also elicit changes in metabolism and stress resistance, similar to those caused by fasting, which are dependent on the amino acid sensing kinase Gcn2 (Peng et al., 2012).

Multiple hormonal changes that typify MS in humans a re observed in rodents maintained on high fat and sugar diets including elevated levels of insulin and leptin and reduced levels of adiponectin and ghrelin. Elevated leptin levels are typically reflective of a pro- inflammatory state, whereas adiponectin and ghrelin can suppress inflammation and increase insulin sensitivity (Baatar et al., 2011; Yamauchi et al., 2001). Local inflammation in hypothalamic nuclei that control energy intake and expenditure may contribute to a sustained positive energy balance in MS (Milanski et al., 2012). Fasting results in a lowering of insulin and leptin levels and an elevation of adiponectin and ghrelin levels. By increasing insulin and leptin sensitivity, suppressing inflammation and stimulating autophagy, fasting reverses all the major abnormalities of the MS in rodents (Singh et al., 2009; Wan et al., 2010). Finally, in addition to its many effects on cells throughout the body and brain, IF may elicit changes in the gut microbiota that protect against MS (Tremaroli and Backhed, 2012). Naturally, the challenge of applying fasting-based interventions to treat MS in humans is a major one, as some obese individuals may have difficulties in following IF for long periods.

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The ProLon� fasting mimicking diet is a 5-day meal program consisting of scientifically developed and clinically tested, natural ingredients which “trick” the human body into a fasting mode. The FMD is low in carbohydrates as well as proteins and it’s high in fats. The ProLon� fasting mimicking diet promotes a variety of healthy benefits, including weight loss and decreased abdominal fat, all while preserving lead body mass, improved energy levels, softer and healthier looking skin, as well as overall health and wellness. The FMD can promote longevity.

Dr. Alex Jimenez D.C., C.C.S.T. Insight

Fasting, Aging, and Disease in Humans

Fasting and Factors Implicated in Aging

Clinical and epidemiological data are consistent wit h an ability of fasting to retard the aging process and associated diseases. Major factors implicated in aging whose generation are accelerated by gluttonous lifestyles and slowed by energy restriction in humans include: 1) oxidative damage to proteins, DNA and lipids; 2) inflammation; 3) accumulation of dysfunctional proteins and organelles; and 4) elevated glucose, insulin and IGF-I, although IGF-1decreases with aging and its severe deficiency can be associated with certain pathologies (Bishop et al., 2010; Fontana and Klein, 2007). Serum markers of oxidative damage and inflammation as well as clinical symptoms are reduced over a period of 2�4 weeks in asthma patients maintained on an alternate day fasting diet (Johnson et al., 2007). Similarly, when on a 2 days/week fasting diet overweight women at risk for breast cancer exhibited reduced oxidative stress and inflammation (Harvie et al., 2011) and elderly men exhibited reductions in body weight and body fat, and improved mood (Teng et al., 2011). Additional effects of fasting in human cells that can be considered as potentially �anti-aging� are inhibition the mTOR pathway, stimulation of autophagy and ketogenesis (Harvie et al., 2011; Sengupta et al., 2010).

Among the major effects of fasting relevant to aging and diseases are changes in the levels of IGF-1, IGFBP1, glucose, and insulin. Fasting for 3 or more days causes a 30% or more decrease in circulating insulin and glucose, as well as rapid decline in the levels of insulin- like growth factor 1 (IGF-1), the major growth factor in mammals, which together with insulin is associated with accelerated aging and cancer (Fontana et al., 2010). In humans, five days of fasting causes an over 60% decrease in IGF-1and a 5-fold or higher increase in one of the principal IGF-1-inhibiting proteins: IGFBP1 (Thissen et al., 1994a). This effect of fasting on IGF-1is mostly due to protein restriction, and particularly to the restriction of essential amino acids, but is also supported by calorie restriction since the decrease in insulin levels during fasting promotes reduction in IGF-1(Thissen et al., 1994a). Notably, in humans, chronic calorie restriction does not lead to a decrease in IGF-1unless combined with protein restriction (Fontana et al., 2008).

IF can be achieved in with a minimal decrease in overall calorie intake if the refeeding period in which subjects overeat is considered. Thus, fasting cycles provide a much more feasible strategy to achieve the beneficial effects of CR, and possibly stronger effects, without the burden of chronic underfeeding and some of the potentially adverse effects associated with weight loss or very low BMIs. In fact, subjects who are moderately overweight (BMI of 25�30) in later life can have reduced overall mortality risk compared to subjects of normal weight (Flegal et al., 2013). Although these results may be affected by the presence of many existing or developing pathologies in the low weight control group, they underline the necessity to differentiate between young individuals and elderly individuals who may use CR or fasting to reduce weight or delay aging. Although extreme dietary interventions during old age may continue to protect from age-related diseases, they could have detrimental effects on the immune system and the ability to respond to certain infectious diseases, wounds and other challenges (Kristan, 2008; Reed et al., 1996). However, IF or PF designed to avoid weight loss and maximize nourishment have the potential to have beneficial effects on infectious diseases, wounds and other insults even in the very old. Nourishment of subjects can be achieved by complementing IF or PF with micro- and macro Studies to test the effect of IF or PF regimens on markers of aging, cancer, cognition and obesity are in progress (V. Longo and M. Mattson).

Fasting and Cancer

Fasting has the potential for applications in both cancer prevention and treatment. Although no human data are available on the effect of IF or PF in cancer prevention, their effect on reducing IGF-1, insulin and glucose levels, and increasing IGFBP1 and ketone body levels could generate a protective environment that reduces DNA damage and carcinogenesis, while at the same time creating hostile conditions for tumor and pre-cancerous cells (Figure 5). In fact, elevated circulating IGF-1 is associated with increased risk of developing certain cancers (Chan et al., 2000; Giovannucci et al., 2000) and individuals with severe IGF-1deficiency caused by growth hormone receptor deficiency, rarely develop cancer (Guevara-Aguirre et al., 2011; Shevah and Laron, 2007; Steuerman et al., 2011). Furthermore, the serum from these IGF-1deficient subjects protected human epithelial cells from oxidative stress-induced DNA damage. Furthermore, once their DNA became damaged, cells were more likely to undergo programmed cell death (Guevara-Aguirre et al., 2011). Thus, fasting may protect from cancer by reducing cellular and DNA damage but also by enhancing the death of pre-cancerous cells.

In a preliminary study of 10 subjects with a variety of malignancies, the combination of chemotherapy with fasting resulted in a decrease in a range of self-reported common side effects caused by chemotherapy compared to the same subjects receiving chemotherapy while on a standard diet (Safdie et al., 2009). The effect of fasting on chemotherapy toxicity and cancer progression is now being tested in clinical trials in both Europe and the US (0S-08-9, 0S-10-3).

Fasting and Neurodegeneration

Our current understanding of the impact of IF on the nervous system and cognitive functions is largely inferred from animal studies (see above). Interventional studies to determine the impact of fasting on brain function and neurodegenerative disease processes are lacking.

After 3�4 month, CR improved cognitive function (verbal memory) in overweight women (Kretsch et al., 1997) and in elderly subjects (Witte et al., 2009). Similarly, when subjects with mild cognitive impairment were maintained for 1 month on a low glycemic diet, they exhibited improved delayed visual memory, cerebrospinal fluid biomarkers of A? metabolism and brain bioenergetics (Bayer-Carter et al., 2011). Studies in which cognitive function, regional brain volumes, neural network activity, and biochemical analyses of cerebrospinal fluid are measured in human subjects before and during an extended period of IF should clarify the impact of IF on human brain structure and function.

Fasting, Inflammation and Hypertension

In humans, one of the best demonstrations of the beneficial effects of long-term fasting lasting one to 3 weeks is in the treatment of rheumatoid arthritis (RA). In agreement with the results in rodents, there is little doubt that during the period of fasting both inflammation and pain are reduced in RA patients (Muller et al., 2001). However, after the normal diet is resumed, inflammation returns unless the fasting period is followed by a vegetarian diet (Kjeldsen-Kragh et al., 1991), a combination therapy that has beneficial effects lasting for two years or longer (Kjeldsen-Kragh et al., 1994). The validity of this approach is supported by four differently controlled studies, including two randomized trials (Muller et al., 2001). Therefore, fasting combined with a vegetarian diet and possibly with other modified diets provides beneficial effects in the treatment of RA. Alternate day IF also resulted in significant reductions in serum TNF? and ceramides in asthma patients during a 2 month period (Johnson et al., 2007). The latter study further showed that markers of oxidative stress often associated with inflammation (protein and lipid oxidation) were significantly reduced in response to IF. Thus, for many patients able and willing to endure long-term fasting and to permanently modify their diet, fasting cycles would have the potential to not only augment but also replace existing medical treatments.

Water only and other forms of long-term fasting have also been documented to have potent effects on hypertension. An average of 13 days of water only fasting resulted in the achievement of a systolic blood pressure (BP) below 120 in 82% of subjects with borderline hypertension with a mean 20 mm Hg reduction in BP (Goldhamer et al., 2002). BP remained significantly lower compared to baseline even after subjects resumed the normal diet for an average of 6 days (Goldhamer et al., 2002). A small pilot study of patients with hypertension (140 mm and above systolic BP) also showed that 10�11 days of fasting caused a 37�60 mm decrease in systolic BP (Goldhamer et al., 2001). These preliminary studies are promising but underscore the need for larger controlled and randomized clinical studies that focus on periodic fasting strategies that are feasible for a larger portion of the population.

For both hypertension and RA it will be important to develop PF mimicking diets that are as effective as the fasting regimens described above but that are also tolerable by the great majority of patients.

Fasting and the Metabolic Syndrome

Periodic fasting can reverse multiple features of the metabolic syndrome in humans: it enhances insulin sensitivity, stimulates lipolysis and reduces blood pressure. Body fat and blood pressure were reduced and glucose metabolism improved in obese subjects in response to an alternate day modified fast (Klempel et al., 2013; Varady et al., 2009). Overweight subjects maintained for 6 months on a twice weekly IF diet in which they consumed only 500�600 calories on the fasting days, lost abdominal fat, displayed improved insulin sensitivity and reduced blood pressure (Harvie et al., 2011). Three weeks of alternate day fasting resulted in reductions in body fat and insulin levels in normal weight men and women (Heilbronn et al., 2005) and Ramadan fasting (2 meals/day separated by approximately 12 hours) in subjects with MS resulted in decreased daily energy intake, decreased plasma glucose levels and increased insulin sensitivity (Shariatpanahi et al., 2008). Subjects undergoing coronary angiography who reported that they fasted regularly exhibited a lower prevalence of diabetes compared to non-fasters (Horne et al., 2012). Anti- metabolic syndrome effects of IF were also observed in healthy young men (BMI of 25) after 15 days of alternate day fasting: their whole-body glucose uptake rates increased significantly, levels of plasma ketone bodies and adiponectin were elevated, all of which occurred without a significant decrease in body weight (Halberg et al., 2005). The latter findings are similar to data from animal studies showing that IF can improve glucose metabolism even with little or no weight change (Anson et al., 2003). It will be important to determine if longer fasting periods which promote a robust switch to a fat breakdown and ketone body-based metabolism, can cause longer lasting and more potent effects.

Conclusions and Recommendations

Based on the existing evidence from animal and human studies described, we conclude that there is great potential for lifestyles that incorporate periodic fasting during adult life to promote optimal health and reduce the risk of many chronic diseases, particularly for those who are overweight and sedentary. Animal studies have documented robust and replicable effects of fasting on health indicators including greater insulin sensitivity, and reduced levels of blood pressure, body fat, IGF-I, insulin, glucose, atherogenic lipids and inflammation. Fasting regimens can ameliorate disease processes and improve functional outcome in animal models of disorders that include myocardial infarction, diabetes, stroke, AD and PD. One general mechanism of action of fasting is that it triggers adaptive cellular stress responses, which result in an enhanced ability to cope with more severe stress and counteract disease processes. In addition, by protecting cells from DNA damage, suppressing cell growth and enhancing apoptosis of damaged cells, fasting could retard and/ or prevent the formation and growth of cancers.

However, studies of fasting regimens have not been performed in children, the very old and underweight individuals, and it is possible that IF and PF would be harmful to these populations. Fasting periods lasting longer than 24 hours and particularly those lasting 3 or more days should be done under the supervision of a physician and preferably in a clinic. IF- and PF-based approaches towards combating the current epidemics of overweight, diabetes and related diseases should be pursued in human research studies and medical treatment plans. Several variations of potential �fasting prescriptions� that have been adopted for overweight subjects revolve around the common theme of abstaining from food and caloric beverages for at least 12 � 24 hours on one or more days each week or month, depending on the length, combined with regular exercise. For those who are overweight, physicians could ask their patients to choose a fasting-based intervention that they believe they could comply with based upon their daily and weekly schedules. Examples include the �5:2� IF diet (Harvie et al., 2011), the alternate day modified fasting diet (Johnson et al., 2007; Varady et al., 2009), a 4�5 day fast or low calorie but high nourishment fasting mimicking diets once every 1�3 months followed by the skipping of one major meal every day if needed (V. Longo, clinical trial in progress). One of the concerns with unbalanced alternating diets such as those in which low calorie intake is only observed for 2 days a week are the potential effects on circadian rhythm and the endocrine and gastrointestinal systems, which are known to be influenced by eating habits. During the first 4 � 6 weeks of implementation of the fasting regimen, a physician or registered dietitian should be in regular contact with the patient to monitor their progress and to provide advice and supervision.

Fasting regimens could also be tailored for specific diseases as stand-alone or adjunct therapies. Results of initial trials of IF (fasting 2 days per week or every other day) in human subjects suggest that there is a critical transition period of 3 � 6 weeks during which time the brain and body adapt to the new eating pattern and mood is enhanced (Harvie et al., 2011; Johnson et al., 2007). Though speculative, it is likely that during the latter transition period brain neurochemistry changes so that the �addiction� to regular consumption of food throughout the day is overcome. Notably, the various fasting approaches are likely to have limited efficacy particularly on aging and conditions other than obesity unless combined with diets such as the moderate calorie intake and mostly plant-based Mediterranean or Okinawa low protein diets (0.8 g protein/Kg of body weight), consistently associated with health and longevity.

In the future, it will be important to combine epidemiological data, studies of long-lived populations and their diets, results from model organisms connecting specific dietary components to pro-aging and pro-disease factors, with data from studies on fasting regimens in humans, to design large clinical studies that integrate fasting with diets recognized as protective and enjoyable. A better understanding of the molecular mechanisms by which fasting affects various cell types and organ systems should lead to the development of novel prophylactic and therapeutic interventions for a wide range of disorders.

Take Home Message

The fasting mimicking diet provides the same benefits of traditional fasting by restricting your calorie intake for five days out of the month instead of completely eliminating all food for several days or even weeks. The ProLon� fasting mimicking diet offers a 5-day meal program which has been individually packed and labeled in precise quantities and combinations for each day. Although the research study above has demonstrated the health benefits of fasting, please make sure to talk to a healthcare professional before starting the ProLon� fasting mimicking diet, 5-day meal program to find out if the FMD, or any other diet, is right for you.

The published, final edited form of the research study referenced above was made available in the NIH Public Access Author Manuscript on PMC February 4, 2015. The scope of our information is limited to chiropractic, spinal health issues, and functional medicine topics. To further discuss the subject matter, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .

Curated by Dr. Alex Jimenez

Referenced from: Nih.gov

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Additional Topic Discussion: Acute Back Pain

Back pain is one of the most prevalent causes of disability and missed days at work worldwide. Back pain attributes to the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience back pain at least once throughout their life. Your spine is a complex structure made up of bones, joints, ligaments, and muscles, among other soft tissues. Injuries and/or aggravated conditions, such as herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief.

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ProLon� Fasting Mimicking Diet Benefits

ProLon� Fasting Mimicking Diet Benefits

Fasting offers numerous health benefits, from increasing insulin sensitivity and promoting weight loss to enhancing the immune system. Although we all want the benefits of fasting, many of us can’t embrace the idea of not eating for extended periods of time. However, what if you could achieve all the healthy advantages of a fast without having to skip meals?

The fasting mimicking diet, sometimes abbreviated as FMD, is a nutritional regimen. It consists of eating natural ingredients for five days which “tricks” the human body into a fasting mode. Research studies have demonstrated the fasting mimicking diet’s ability to improve overall health and wellness. Below, we will discuss the benefits of the fasting mimicking diet.

How Does the Fasting Mimicking Diet Work?

By restricting the food you eat, the fasting mimicking diet can provide similar health benefits as traditional fasting like reduced inflammation and fat burning. The difference, however, is that instead of not eating any food for several days or weeks, you’re simply limiting your calorie intake for five days. You can do the FMD once a month or every other month to promote well-being.

The ProLon� fasting mimicking diet, 5-day meal program offers individually packed and labeled foods for each day in precise quantities and combinations. The meal program consists of ready-to-eat or easy-to-prepare, plant-based foods, such as bars, soups, snacks, supplements, a drink concentrate, and teas. The products are scientifically formulated and great tasting.

FMD Macronutrient Ratios

First, you will restrict your calories to 1,100 calories on day one of the FMD. Then, you will restrict your calories to 800 calories on the other four days. What you eat and in what ratios you eat those foods is fundamental in the fasting mimicking diet. Healthcare professionals will recommend different ratios of macronutrients, the three basic components of every diet.

The most common recommendation is to eat 1,100 calories following a macronutrient ratio of 34 percent carbohydrates, 10 percent proteins, and 56 percent fats on day one. For the remaining four days, the most common recommendation is to eat 800 calories following a macronutrient ratio of 47 percent carbohydrates, 9 percent proteins, and 44 percent fats.

Other healthcare professionals recommend a macronutrient ratio with as much as 80 percent of calories coming from fat, and 10 percent from carbohydrates and proteins, respectively. According to Dr. Valter Longo, creator of the FMD, “the fasting mimicking diet allows the natural process of starvation, including autophagy, and stem cell regeneration, to occur without interruption.

The Science Behind the FMD

Research studies have demonstrated that limiting calorie intake provides many benefits for the lifespan of animals. However, what does the science say about the benefits of the fasting mimicking diet on humans? A recent research study evaluated the effects of the FMD in people and found some promising outcome measures. The research study was conducted on 100 healthy participants.

Half of the participants followed the ProLon� fasting mimicking diet, 5-day meal program every month and the other half of the participants followed a regular diet. After three months, the FMD group experienced weight loss, including visceral fat reduction, as well as decreased blood glucose, blood pressure, and markers of inflammation. The FMD group also experienced a drop in insulin-like growth factor 1, more frequently known as 1GF-1, which is considered to be a biomarker for cancer development.

Dr Jimenez White Coat
The ProLon� fasting mimicking diet, 5-day meal program provides numerous health benefits while providing balanced nourishment. The FMD can promote weight loss as well as maintain healthy levels of blood glucose, BP, cholesterol, and triglycerides, C-reactive proteins, stem cells, and insulin-like growth factor 1 or IGF-1. Following the FMD alongside healthy lifestyle modifications can help improve overall health and wellness. Dr. Alex Jimenez D.C., C.C.S.T. Insight

Other Fasting Mimicking Diet Benefits

The FMD has been demonstrated to give you protective, regenerative, and rejuvenating advantages while continuing to provide you with the balanced nourishment you need. Below, we will discuss several other health benefits of the fasting mimicking diet.

Decreases Cholesterol

The same research study mentioned above also demonstrated that after three months, the FMD group experienced decreased levels of total and bad LDL cholesterol. When we have increased levels of cholesterol in our blood, it can cause plaque to build up in our arteries, causing the hardening, and the narrowing of the arteries. This may lead to a heart attack and coronary heart disease. If you combine the FMD with lifestyle modifications, you can lower and maintain healthy cholesterol levels and keep your heart healthy.

Reduces Inflammation

We already mentioned that the FMD research study demonstrated it could decrease inflammation. However, we should first discuss what inflammation is and what it can do to the human body. Inflammation is one of the human body’s defense mechanisms. Your inflammation is triggered by your immune system to protect you from foreign invaders that could cause infection, illness, or injury.

By way of instance, let’s imagine you get a splinter in your finger. Your finger will become red and inflamed almost immediately. Your body is utilizing inflammation to protect itself from this foreign object. When you get a cut or an insect bite, the same holds true. However, how does inflammation affect our well-being? Chronic inflammation can lead to many chronic diseases, such as heart disease, diabetes, multiple sclerosis, and cancer. The FMD has the potential to reduce the possibility of developing chronic diseases.

Improves Brain Health

The fasting mimicking diet can also help improve our brain health. In a 2015 animal research study, the FMD improved cognition and promoted the regeneration of neurons in the brains of mice. Additionally, it decreased the markers of aging in the subjects.

Can Help Reverse Diabetes

The FMD can positively affect insulin production. In another animal research study, blood glucose levels were preserved and more insulin-producing beta cells were produced in mice. The Science Translational Medicine research study also demonstrated that the participants following the FMD experienced a reduction in glucose levels. Although further evidence is required, there are strong indications that healthy lifestyle modifications can help control and even reverse diabetes.

How to Start the Fasting Mimicking Diet

I encourage you to work with your healthcare professional if you’re interested in the FMD. You will also need advice and guidance from a qualified healthcare professional to help you decide on your proper macronutrient ratios. In summary, you should be eating a diet full of plant-rich whole foods, with an emphasis on nuts and olives. You could also eat soups and broths as well as herbal teas.

Make sure you also avoid the consumption of alcohol and carbonated drinks. Instead, you can drink two cups of black tea or coffee. Furthermore, you shouldn’t exercise vigorously during those five days. Consider taking a gentle walk around the block.

Research studies have demonstrated promising results with the fasting mimicking diet. However, the FMD may not be for everyone. Pregnant women and older adults shouldn’t try the FMD. If you’d like to experience the health benefits of the FMD yourself, talk with your doctor and/or a nutritionist. Doing more than one cycle every month could ultimately affect your overall health and wellness.

The scope of our information is limited to chiropractic and spinal health issues as well as functional medicine topics and discussions. To further discuss the subject matter, please feel free to ask Dr. Alex Jimenez or contact us at�915-850-0900�.

Curated by Dr. Alex Jimenez

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Additional Topic Discussion:�Acute Back Pain

Back pain�is one of the most prevalent causes of disability and missed days at work worldwide. Back pain attributes to the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience back pain at least once throughout their life. Your spine is a complex structure made up of bones, joints, ligaments, and muscles, among other soft tissues. Injuries and/or aggravated conditions, such as�herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief. �

Xymogen Formulas - El Paso, TX

XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.

Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.

Please call our office in order for us to assign a doctor consultation for immediate access.

If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.

xymogen el paso, tx

For your convenience and review of the XYMOGEN products please review the following link.*XYMOGEN-Catalog-Download

* All the above XYMOGEN policies remain strictly in force.

***

Functional Medicine Part 4: Women’s Hormones

Functional Medicine Part 4: Women’s Hormones

Functional Medicine Doctor Explains Women’s Hormones

We discussed the basics for men�s hormones. Now let�s discuss the basics for women�s hormones. Unfortunately, the effects of our diet and our environment become more obvious in the anatomy and biochemistry of women. These may frequently manifest as hormone imbalances and they can greatly affect their quality of life. Mood disorders have become an epidemic.

By way of instance, depression affects 20 percent of women, about twice as much in women than in men. And premenstrual syndrome, or PMS, affects between 60 and 75 percent of women in the United States. Infertility is also an epidemic which affects more than one in seven couples and it is generally managed by reproductive endocrinologists through invasive procedures, hormone treatments, and in vitro fertilization, or IVF, often without even evaluating what is the cause of the reproductive health issues. I�ve helped many women improve their hormone imbalances through the basic principles of functional medicine.

Now, these are only several of the reasons why we need to determine the source of hormonal imbalances in women. And I believe this knowledge can help women find the answers they need to improve their overall health and wellness. Most importantly, you need to learn to listen to what your body is telling you. After all, the human body is one of the best doctors.

Taking Control of Women’s Hormones

Women�s hormones are much more complex than men�s hormones because they�re constantly changing based on their cycle as well as on their stage of life. If you�re experiencing mood swings, irregular cycles, menstrual pain, heavy bleeding, infertility, weight gain, and brain fog, functional medicine can help improve your symptoms by balancing your hormones.

Next, we will discuss the following tests you should include in your lab panels if you�re a female, including the follicle stimulating hormone, or FSH, the luteinizing hormone, or LH, progesterone, testosterone, DHEA, and estrogen. Also, it�s important to note that there isn�t just a single estrogen hormone. There are many different types of estrogens, such as estradiol.

So, let�s discuss the differences between pre-menopausal women and post-menopausal women. Pre-menopausal women should experience regular cycles every 28 days that last two or three days without a lot of pain, not too heavy bleeding, and no PMS. However, most women don�t experience regular cycles. A proper nutrition consisting of low sugar and starch, high fat, and more fiber can help correct abnormal cycles. A plant-rich diet can also help improve abnormal cycles. Caffeine and alcohol consumption can even cause hormone imbalances in women. Proper nutrition, including taking supplements like magnesium, B vitamins and fish oil, exercise, sleep, and stress management can help regulate your hormones. This is generally enough to help most women.

A doctor or functional medicine practitioner can also help balance your hormones. Because women�s hormones fluctuate throughout their cycle, progesterone and estrogen levels may be different for each woman. Also, depending on the hormonal health issues, patients may need to run their hormone lab panel tests on either day three or day 21 of their cycle for best results.

Furthermore, we will also need to evaluate your ratio of hormones, like that of estrogen to progesterone, because these can be the cause of numerous symptoms for many women. Estrogen dominance is one of the most common problems associated with a woman�s hormone ratio. Progesterone levels in women should be at their highest during the last half of their cycle. The hormone ratio between progesterone and estrogen should be 10 to one. However, if the human body is not producing the required amounts of progesterone, symptoms of estrogen dominance may begin to manifest, regardless if the human body�s estrogen levels themselves are low. Symptoms of estrogen dominance can include: anxiety, heavy bleeding, PMS, breast tenderness, shorter cycles or spotting between cycles, infertility, fluid retention, weight gain, and sleeping problems.

FSH is produced by the brain to help the follicles and the ovaries prepare to release an egg. LH is another hormone produced by the brain which triggers the release of an egg into the uterus so that conception can occur. LH also helps produce progesterone during the second half of your cycle, which may be another reason why many women have low progesterone levels.

These hormones are fundamental to look at if you�re trying to have a baby. The elevated hormone ratio between LH and FSH can demonstrate the presence of a common health issue known as PCOS or polycystic ovarian syndrome. PCOS is actually not an ovarian health issue. As a matter of fact, it�s a common problem associated with a poor diet and insulin resistance. An increased consumption of sugar and starch can cause irregular cycles, heavy bleeding, acne, hair loss, and infertility.

As for post-menopausal women, hormone blood panel tests are just as important and we generally don�t need to worry about having to evaluate them on a specific day of the month. Also, when we test a woman who�s in their perimenopause, their hormones may be tremendously unstable. Therefore, it�s ultimately essential to diagnose a woman�s symptoms to help treat the source of the health issue.

We previously discussed the importance of testosterone in men. However, testosterone is also important in women. Many women visit numerous doctors after experiencing low energy levels as well as a decreased sex drive. Most doctors will associate these symptoms with aging or they may even tell them it�s all in their head and simply prescribe them some Prozac. But if we were to run a blood panel test on them, their testosterone levels would often come back undetectable. It�s no wonder why women don�t feel like themselves after they�ve lost their libido and their vitality.

Total testosterone levels in women should be between 60 and 80 while free testosterone levels should be over 0.5. Testosterone is fundamental towards maintaining lean muscle mass and optimizing energy. Testosterone is also important for clear brain function.

Now women, if you have low testosterone levels, this may be causing you to experience a reduced sex drive or it may even be making you feel fatigue. However, this isn�t always the cause of these symptoms. That�s why it�s so essential for women to test their sex hormone levels. Testosterone is what is known as an androgen, or a male hormone, but it�s also found in women. Other androgens that help contribute to male characteristics include androstenedione, dihydrotestosterone, or DHT, and DHEA. In polycystic ovarian syndrome, or PCOS, women will commonly develop elevated levels of any of these hormones. Women who consume a lot of sugar and starch may also develop acne, hair loss or they may even grow facial hair. All of these are symptoms of too much testosterone in women.

PCOS affects approximately 8 to 12 percent of women. As previously mentioned, this health issue is a metabolic problem caused by poor nutrition which ultimately affects the human body�s insulin levels. It can also affect other hormones, such as the androgens we previously discussed. When women develop insulin resistance, the production of male sex hormones can increase. Other tests are important when PCOS is caused by FSH and LH hormones.

FSH generally triggers ovulation. However, if a woman�s FSH is too low due to PCOS, ovulation, and therefore, conception can�t occur. This is why women with PCOS are also commonly diagnosed with infertility. And the key is in a woman�s LH to FSH ratio. Increased levels of LH can stimulate androgens, such as testosterone, and decreased levels of FSH can stimulate the follicles and estrogen. Furthermore, facial hair or thinning of the head hair, irregular menstrual cycles, heavy bleeding, and weight gain in women can be symptoms of PCOS. Although PCOS is believed to be a health issue which exclusively affects overweight women, we�re starting to see an increase of women with healthy weights develop PCOS.

Because functional medicine focuses on finding the source of the health issue, if we see cysts on your ovaries or if any other lab tests indicate the presence of PCOS, we won�t simply stop there. And most often, we just have to look back at the patient�s diet. The high consumption of sugar and starch causes a tremendous metabolic disturbance which can cause a variety of other health issues. We will discuss these various metabolic conditions in another article.

Dr Jimenez White Coat
Hormones are fundamental to women’s health. Female sex hormones, including estrogen and progesterone, influence a woman’s mood, menstruation, pregnancy, menopause, and more. A variety of other hormones can also affect other aspects of a woman’s health. One of the most common health issues associated with hormonal imbalances in women is known as polycystic ovarian syndrome or PCOS. Women can be tremendously affected by hormone fluctuations. It’s essential for women to seek help from a doctor to find out if their symptoms are caused by hormone imbalances. Functional medicine can also help regulate hormones. Dr. Alex Jimenez D.C., C.C.S.T. Insight

Understanding Women’s Hormones

We measure hormonal imbalances through simple blood tests and we can also measure hormones through urine tests. Tests known as the �DUTCH� and the �Essential Estrogens� are provided by Genova to determine hormone metabolites. These can also determine the downstream breakdown products of hormones in order to help demonstrate what�s happening with your hormone metabolism.

Now, let me explain what are some of the most important things doctors or functional medicine practitioners look at when ordering a DUTCH test or an Essential Estrogens test. Hormone metabolism tests demonstrate your absolute hormone levels as well as which types of metabolites are being triggered. And this is what we utilize to look at your estrogen levels, androgen levels, and progesterone levels, as well as your cortisol levels, which we will discuss later. These are essential metabolites that can be found through our saliva, blood, and urine. We even look at all the different varieties of estrogens which get broken down by the liver.

So, it�s fundamental that we look carefully at our hormone levels. Testing for hormonal imbalances in both men and women can tell us a lot about what�s causing our symptoms as well as what we can do to treat them. We can recommend a series of lifestyle modifications, including guidance and advice in nutrition and exercise. At least that�s what a good functional medicine doctor would do.

The scope of our information is limited to chiropractic and spinal health issues as well as functional medicine topics and discussions. To further discuss the subject matter, please feel free to ask Dr. Alex Jimenez or contact us at�915-850-0900�.

Curated by Dr. Alex Jimenez

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Additional Topic Discussion:�Acute Back Pain

Back pain�is one of the most prevalent causes of disability and missed days at work worldwide. Back pain attributes to the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience back pain at least once throughout their life. The spine is a complex structure made up of bones, joints, ligaments, and muscles, among other soft tissues. Injuries and/or aggravated conditions, such as�herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief. �

Xymogen Formulas - El Paso, TX

XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.

Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.

Please call our office in order for us to assign a doctor consultation for immediate access.

If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.

xymogen el paso, tx

For your convenience and review of the XYMOGEN products please review the following link.*XYMOGEN-Catalog-Download

* All the above XYMOGEN policies remain strictly in force.

***

Functional Medicine Part 4: Men’s Hormones

Functional Medicine Part 4: Men’s Hormones

Functional Medicine Doctor Explains Men’s Hormones

Hello there, it�s Dr. Alex Jimenez again and welcome to part four of �Taking Control of your Healthcare�. Today, we�re going to discuss hormones. Hormones regulate most of the human body�s systems as they are recognized as the messenger molecules of the endocrine system. Hormone imbalances can cause subtle changes, however, their effects can tremendously impact an individual�s overall health and wellness. And what�s worse, most healthcare professionals don�t treat hormonal imbalances unless they�ve already been considered extreme.

The sex hormones, the thyroid hormones, and the adrenal hormones are the most important hormones we have to keep in balance. There�s a variety of other hormones, of course, but health issues associated with those are often more rare. Many doctors generally won�t test a person for hormone imbalances unless they�ve been trying to conceive a baby or they have sexual dysfunction or any other health issue of this type. And frequently, many doctors miss other problems by performing a screening test rather than a complete test.

What are Hormones?

Hormones are essential towards mental health, gut health, and reproductive health. In functional medicine, we even believe that hormones are vital towards maintaining a healthy immune system. Even if you�re not trying to conceive a baby or if you don�t have sexual dysfunction, it�s important for both men and women to known what their hormone levels look like.

Now, let�s discuss hormonal imbalances in sex hormones. First of all, How does a hormone imbalance manifest itself? Do you experience mood swings and fluctuations in your energy levels? Or if you�re a female, do you experience symptoms of PMS? Or perhaps you need coffee to wake up in the morning and wine to sleep at night? Has your sex drive, or libido, decreased? Do you have brain fog? Or is it difficult for you to focus on tasks?

If you�ve experienced any of these symptoms, you might have a hormonal imbalance in your sex hormones. Hormones are small molecules in charge of transmitting signals from one body system to another. But, if these molecules aren�t functioning accordingly, our energy levels and our mood can be tremendously affected. If you feel that something is off within your own body, talk to your doctor and seek proper testing. Don�t simply guess.

Let�s begin by discussing how you test your hormones. In functional medicine, we can test through saliva, blood, urine, and even stool. But, which is best for testing hormones? The truth is, knowing how and when to test your hormones is important because testing can depend on the marker that you want to look at. By way of instance, blood testing is one of the best and most affordable if you�re simply looking for a preliminary screening. A functional medicine doctor can also determine when a urine test will be more helpful than a blood test or a saliva test.

Taking Control of Men’s Hormones

So, now that you know how to test your hormones, we�ll discuss the different health issues caused by hormonal imbalances in the sex hormones of both men and women. First, let�s talk about men. As for the women, this is still an essential topic for you to learn about because the men in your lives are much less likely to schedule a doctor�s appointment for themselves.

Approximately 39 percent of men over the age of 45 have low levels of testosterone, or what�s known as low T. Elevated insulin levels associated with diabetes and obesity can lower your testosterone levels, which in turn, can increase estrogen levels. When testosterone goes down, your sex drive, or libido, and other functions can be tremendously affected. Excess consumption of sugar and starch can have different impacts for both men and women. Additionally, the utilization of certain drugs and/or medications, lack of exercise and physical activity, as well as inflammation, can also contribute to lower testosterone levels. While the majority of doctors won�t test testosterone levels in a man unless they have sexual dysfunction, I always want to make sure to test the sex hormones if a man has belly fat.

I would also like to discuss the serious side effects of a drug/medication which is commonly prescribed for sexual dysfunction. Statins can help lower cholesterol, however, did you know that your testosterone is made from cholesterol? That�s right. And when you start taking a drug/medication which was designed to decrease your cholesterol, you may also potentially be decreasing your sex hormones. It�s well-known that statins can decrease testosterone, leading to sexual dysfunction and even sometimes causing men to grow breasts, a condition known as gynecomastia. Side effects like these occur when we don�t treat the source of a health issue.

What you eat, including mainly sugar and starch, can be associated with your low testosterone levels and your abnormal cholesterol levels. Treatments like these where you take a drug for one thing but then end up taking another medication for the side effects of the fist medicine is unfortunately something that happens a lot in the medical field, and it can be a real nightmare.

Male testosterone levels are decreasing so much with each generation that normal reference ranges for testosterone levels in males are changing. But, that�s not something we want to happen. We don�t want these abnormal changes to become normal. Therefore, shouldn�t we be trying to find out why the overall health and wellness of our population is decreasing at such an alarming rate rather than lowering our normal standards of well-being?

Before we do that, however, we first have to understand why this problem is happening. From our increased exposure to toxins and our elevated levels of stress to our higher consumption of processed foods, these are only several of the more obvious reasons why our hormones are being affected.

In conventional medicine, the reference ranges for testosterone are between 264 and 916.

When you think about it, however, this is a tremendous range. Does a man with a testosterone level of 265 have the same sexual function as a man with a testosterone level of 916? Most definitely not. Yet these two people are classified under the same category. And with that in mind, what are the optimal reference ranges for testosterone? Men under the age of 30 should have a testosterone level of over 700, and men over the age of 30 should have a testosterone level of at least 500.

Evaluating men�s total testosterone levels is essential but we also need to evaluate their active hormone levels, or their free testosterone levels. Testosterone is carried around on what is known as a sex hormone binding globulin, which then releases it as the human body needs it. This carrier protein is found in the blood and when there�s too much of it, it becomes difficult for the human body to release testosterone when it�s needed.

In men, free testosterone levels should be of at least 10 but, they should optimally be closer to 15 or 20. Additionally, your doctor should check the sex hormone binding globulin or SHBG. As we discussed before, this carrier protein for testosterone and other hormones, can decrease your free testosterone levels. If you don�t check your SHBG, your total testosterone levels might be normal but your free testosterone levels might be too low.

By way of instance, SHBG is similar to a bus filled with many workers. In this case, the workers are testosterone. When we have too many buses, the majority of the workers will stay on the bus while only a few will be out doing their job. A man can have a total testosterone level of 700, however, if they have a free testosterone level of only 5, they�re bound to still feel like they have a total testosterone level of 300.

In summary, we want to make sure that our total testosterone level is over 500 or better, over 600 and we also want to make sure that our free testosterone level is between 15 and 20.

Another hormone you might want to make sure you get tested for is known as dehydroepiandrosterone, or DHEA. DHEA is a precursor hormone for testosterone. It�s also an adrenal hormone, however, we will discuss this later in another article. If an individual�s DHEA is too low, it can indicate that the adrenal glands, which are in charge of the human body�s stress response, may not be functioning appropriately. DHEA levels should be between two to 400.

DHEA, or dehydroepiandrosterone, can be supplemented directly. Many doctors and functional medicine practitioners may also implement stress-relieving methods and techniques into your life, such as mindfulness meditation and yoga, to treat the source of the health issue. Herbal supplements can also help regulate DHEA as well as testosterone levels.

Now, we will discuss a fundamental hormone that is generally only considered to be important in female health, however, this hormone also plays an essential role in men; estrogen. Estrogen helps maintain a healthy sex function as it promotes your libido. It is also protective for the brain. In men�s health, estrogen is often demonized because it can cause health issues like breast development if estrogen levels are too high in men. But, normal estrogen levels are fundamental towards maintaining hormone balance as well as mental health.

Estrogen can increase in men with diabetes and obesity. Elevated insulin exchanges more testosterone into estrogen which may cause additional symptoms like fatigue. This can also create more problems alongside sexual dysfunction, including hair loss. So, if you have less than optimal testosterone levels, you should seek help from a doctor or functional medicine practitioner to find out why. And looking at your estrogen levels is a great place to start.

There are two types of estrogen tests which can help demonstrate your estradiol and estrone levels. These are important markers to look at because one can be elevated while the other can be in the normal range. The brain is the other place you can look at to determine your estrogen levels. Your brain produces hormones which can stimulate sex hormones, such as the follicle stimulating hormone, or FSH, and the luteinizing hormone, or LH, which helps produce testosterone and sperm within the testicles. If your LH is low, then your low testosterone levels may be caused by a brain health issue. However, it�s much more likely that sugar and starch consumption may be causing hormonal imbalances in your sex hormones.

Approximately 70 percent of the testosterone deficiencies in the United States are associated with insulin resistance due to diabetes and obesity. So, if your diet is filled with sugar and starch or if you have belly fat, you may already have decreased testosterone levels.

Dr Jimenez White Coat

Hormones are secreted directly into the blood stream in order to control a variety of bodily functions. These can affect growth and development, mood, sexual function, reproduction, and metabolism. As a fundamental part of the endocrine system, hormone imbalances can have a tremendous effect on our overall health and wellness. Men’s hormones, by way of instance, can significantly impact a man’s quality of life. Research studies have demonstrated that decreased testosterone in men can cause a variety of health issues. Evaluating sex hormones in both men and women is essential towards overall health and wellness. Dr. Alex Jimenez D.C., C.C.S.T. Insight

Understanding Men’s Hormones

While we keep discussing the importance of lab tests, we also need to keep asking ourselves why these health issues are happening in the first place. The answers trace back to the basics of health and wellness. What are you eating? Do you participate in exercise or physical activities? Do you sleep properly? Do you have stress? What are your nutrient levels? Of course, several of these answers require more evaluations. That�s why I highly recommend you find a functional medicine doctor who can help get you on the right path towards optimal health and wellness. Most of the time, basic lifestyle modifications including diet, exercise, stress management, sleep and supplements can help. Other times you may need hormone replacement therapy.

The scope of our information is limited to chiropractic and spinal health issues as well as functional medicine topics and discussions. To further discuss the subject matter, please feel free to ask Dr. Alex Jimenez or contact us at�915-850-0900�.

Curated by Dr. Alex Jimenez

Green Call Now Button H .png

Additional Topic Discussion:�Acute Back Pain

Back pain�is one of the most prevalent causes of disability and missed days at work worldwide. Back pain attributes to the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience back pain at least once throughout their life. The spine is a complex structure made up of bones, joints, ligaments, and muscles, among other soft tissues. Injuries and/or aggravated conditions, such as�herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief.

Xymogen Formulas - El Paso, TX

XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.

Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.

Please call our office in order for us to assign a doctor consultation for immediate access.

If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.

xymogen el paso, tx

For your convenience and review of the XYMOGEN products please review the following link.*XYMOGEN-Catalog-Download

* All the above XYMOGEN policies remain strictly in force.

***

An Integrative Holistic Approach To Migraine Headaches

An Integrative Holistic Approach To Migraine Headaches

Holistic: Migraine headaches are typically debilitating, and require a comprehensive approach for successful treatment. It is helpful to consider migraine headache as a symptom of an underlying imbalance, rather than simply a diagnosis. A holistic approach is a satisfying way to think about and treat migraine headache. Physicians trained in this approach will consider a broad array of features that may contribute to the experience of migraine headache, including disturbances within the following key areas:

  • Nutrition
  • Digestion
  • Detoxification
  • Energy production
  • Endocrine function
  • Immune system function/inflammation
  • Structural function
  • Mind-body health

Migraine headache is an excellent example of biologic uniqueness; the underlying factors participating in each individual�s outcome may differ quite a bit from person to person. The journey of identifying and addressing these factors often results in an impressive improvement in frequency and intensity of the expression of migraine. Committed individuals will find the added benefit of better general health along the way.

Nutritional Considerations: Holisitic

Food Allergy/Intolerance

Numerous well-designed studies have demonstrated that detection and removal of foods not tolerated will greatly reduce or eliminate migraine manifestations. True allergy may not be associated with migraine in most individuals, but food intolerance is more common. Migraine frequency and intensity have been demonstrated to respond well to elimination diets, in which commonly offending foods are removed for several weeks. Elimination diets are easy to perform (although they do require a high degree of commitment and education), and can help in identifying foods that are mismatched to an individual. The majority of patients who undergo an elimination diet learn that their diets were contributing to chronic symptoms, and they typically feel much better during the elimination phase. Common foods that act as migraine triggers include: chocolate, cow�s milk, wheat/gluten grains, eggs, nuts, and corn. In children specifically, common migraine triggers include cheese, chocolate, citrus fruits, hot dogs, monosodium glutamate, aspartame, fatty foods, ice cream, caffeine withdrawal, and alcoholic drinks, especially red wine and beer.

There are several methods which may be used to detect food allergies. Laboratory testing can be convenient, but is not always a reliable means of detecting food intolerance. (See Summary of Recommendations for information on how to implement the elimination diet).

Foods such as chocolate, cheese, beer, and red wine are believed to cause migraine through the effect of �vasoactive amines� such as tyramine and beta-phenylethylamine. These foods also contain histamine. Individuals who are sensitive to dietary histamine seem to have lower levels of diamine oxidase, the vitamin B6-dependent enzyme that metabolizes histamine in the small bowel. The use of vitamin B6 improves histamine tolerance in some individuals, presumably by enhancing the activity of this enzyme.

Other diet-related triggers associated with migraine headache include: glucose/insulin imbalances, excessive salt intake, and lactose intolerance. Aspartame, commonly used as a sweetener, may also trigger migraines. Each of these factors may be readily avoided by adopting more conscious eating habits, and by carefully reading labels.

Magnesium

An estimated 75% of people consuming the standard American diet (SAD) are not getting adequate magnesium, and it is felt to represent one of the most common micronutrient deficiencies, manifested by a diverse range of problems. Though many elements can contribute to magnesium depletion, stress is among them, and both acute and chronic stress are associated with increased episodes of migraine. Daily doses of magnesium should be first line considerations for migraine sufferers (caution if kidney function is impaired), and intravenous magnesium can be very helpful in an emergency room setting, but probably only works to terminate an acute migraine if the individual is truly magnesium deficient.

Essential Fatty Acids

It is important to remember that the brain is largely composed of fat. Although essential fatty acids have not received much research attention relative to migraine, there may be a significant role of fatty acids and their metabolites in the pathogenesis of migraine headache. Two small placebo-controlled studies demonstrated that omega-3 fatty acids significantly outperformed placebo in reducing headache frequency and intensity. High quality fish oil should always be used. A good frame of reference is that each capsule should contain at least 300 mg of EPA and 200 mg of DHA. A reasonable starting dose would be two to four capsules twice daily with meals.

Digestive Function: Holistic

Holistic practitioners are generally sensitive to the centrality of the gastrointestinal tract in producing overall health. Though we utilize a reductionistic approach to understanding human anatomy and physiology, we might consider that no system functions as an independent entity (GI, endocrine, cardiovascular, immune, etc.), and that a complex symphony of interrelated functions cuts across organ systems. For example, much of the immune system is found in the Peyer�s patches of the GI tract; in this light, we can see how food, chemicals, and unhealthy microbes might produce immune system activation from gastrointestinal exposure. We also recognize the importance of a balanced ecosystem of intestinal microbes; intestinal dysbiosis, or disordering of the gastrointestinal ecology, may readily produce symptoms, both within and distant from the GI tract. Some colonic bacteria act upon dietary tyrosine to produce tyramine, a recognized migraine trigger for some individuals. H. pylori infection is a probable independent environmental risk factor for migraine without aura, especially in patients not genetically or�hormonally susceptible. A high percentage of migraine patients experienced relief from migraines when H. Pylori infection was eradicated.

Detoxification: Holistic

Patients with migraine headache sometimes report that strong chemical odors such as tobacco smoke, gasoline, and perfumes may act as triggers. It is not uncommon for migraineurs to report that they are triggered by walking down the laundry soap aisle in the grocery store. Support for phase 1 and especially phase 2 detoxification may be beneficial for these individuals, as toxic overload or impaired enzymes of detoxification could theoretically be a significant mediator of headaches. Susceptibility to toxicity may be potentiated by a combination of excessive toxic exposures, genetic polymorphisms leading to inadequate detoxification enzyme production, or depletion of nutrient cofactors that drive phase two detoxification conjugation reactions Support for detoxification function is particularly important in modern life, given our exposure to unprecedented high levels of toxic chemicals. Some nutrients that supply support for detoxification function include: n-acetyl cysteine (NAC), alpha lipoic acid, silymarin (milk thistle), and many others.

Energy Production: Holistic

Riboflavin (Vitamin B2)

Energy production within the parts of the cell called mitochondria can be impaired in some migraine sufferers. Riboflavin is a key nutrient that is involved in energy production at this level. Riboflavin at 400 mg/day is an excellent therapeutic choice for migraine headache because it is well tolerated, inexpensive, and provides a protective effect from oxidative toxicity. Its use in children has been investigated, leading to similar conclusions,suggesting that, for pediatric and adolescent migraine prophylaxis, 200 mg per day was an adequate dose, but four months were necessary for optimal results.

Coenzyme Q10

CoenzymeQ10 (CoQ10) is also a critical component of energy function, and is an important antioxidant. Evidence supports the administration of CoQ10 in reducing the frequency of migraines by 61%. After three months of receiving 150 mg of CoQ10 at breakfast, the average number of headache days decreased from seven to three per month. Another study, using 100 mg of water soluble CoQ10 3x/day, revealed similar results. CoQ10 deficiency appears to be common in the pediatric and adolescent population, and can be an important therapeutic consideration in these age groups. Like riboflavin, CoQ10 is well tolerated (though expensive), with little risk of toxicity. It must be used with extreme caution in patients who also take warfarin, as CoQ10 may counteract the anticoagulation effects of warfarin. It is also noteworthy that many medications can interfere with CoQ10 activity, including statins, beta-blockers, and certain antidepressants and antipsychotics.

Endocrine (Hormone) Function

Female Hormones

It does not appear coincidental that migraine onset correlates with the onset of menstruation and that episodes are linked to menstruation in roughly 60% of female migraineurs. Although there is no universal agreement over the precise relationship between female hormones and migraine headache, it is apparent that the simultaneous fall of estrogen and progesterone levels before the period correlates with menstrual migraine. Estrogen gel used on the skin can reduce headaches when used premenstrually. Some researchers have found that continuous use of estrogen may be necessary to control menstrual migraines, which tend to be more severe, frequent, longer lasting, and debilitating than general migraines. Although published studies are lacking, many practitioners have used transdermal or other bioidentical forms of progesterone premenstrually with success. Of course, the risks of using hormones must be weighed against the benefits. Interestingly, administration of magnesium (360 mg/day) during second half of the menstrual cycle in 20 women with menstrually related migraines resulted in a significant decrease of headache days.

Melatonin

Melatonin, the next downstream metabolite of serotonin, is important in the pathogenesis of migraines. Decreased levels of plasma and urinary melatonin have been observed in migraine patients, and melatonin deficiency appears to increase risk for migraine. Melatonin has been used with some success, presumably via a restorative effect on circadian rhythms. A small study in children demonstrated significant improvement in their migraine or tension headache frequency with a 3 mg nightly dose of melatonin Melatonin appears to modulate inflammation, oxidation, and neurovascular regulation in the brain, and in one study, a dose of 3 mg/day was shown to be effective in reducing migraine headache frequency by at least 50% in 25 of 32 individuals. Ironically, some patients anecdotally report an increase of headaches (generally not migraine) when administered melatonin. The brains of migraineurs do not seem adaptable to extremes; a regular schedule of sleep and meals and avoidance of excessive stimulation are advisable to reduce excessive neural activation.

Immune Function/Inflammation: Holistic

Medications that produce an anti-inflammatory effect, such as aspirin and nonsteroidal agents, frequently produce an improvement in migraine symptoms during an acute attack. The herbs described below also play a role in reducing inflammation. Inflammation and oxidative stress can be identified in many conditions and disease states. It is important to acknowledge that the standard �modern� lifestyle is pro-inflammatory; our bodies are constantly reacting to one trigger after another (foods mismatched to our physiology, toxic burden, emotional stressors, excessive light and other stimulation) that activate our inflammatory cytokines (messengers of alarm). Providing broad-based support through lifestyle change and targeted nutrients may improve outcomes substantially, and this may be achieved foundationally by simplifying our�ingestions/exposures and supporting metabolic terrain. Herbal therapies are included in this section because of their relevant effects upon inflammation.

Feverfew (Tanacetum parthenium)

The precise mechanism of action of feverfew as a migraine preventive is unknown Though at least three studies found no benefit with feverfew, several controlled studies have revealed favorable results in improving headache frequency, severity, and vomiting when feverfew was compared to placebo. There are several caveats that should accompany the use of this herb:

  • Because of its anti-platelet effects, feverfew must be used with caution in patients on blood thinning products; avoid in patients on warfarin/Coumadin.
  • Feverfew does not have a role in managing acute migraine headache.
  • When withdrawing feverfew, do so with a slow taper, since rebound headache may occur.
  • Feverfew is not known to be safe during pregnancy and lactation.
  • Proceed with caution if an individual has an allergy to other members of the Asteraceae family (yarrow, chamomile, ragweed).
  • Most commonly reported adverse effects are oral ulceration (particularly for those chewing the leaves raw), and GI symptoms, reversible with discontinuation.

Feverfew is otherwise well tolerated. The typical dosage range is 25-100 mg 2x/day of encapsulated dried leaves with meals.

Butterbur (Petasites hybridus)

Butterbur is another effective herbal therapy for migraine headache. Butterbur is well tolerated, with no known interactions. Some individuals have reported diarrhea when using butterbur. In one study, its efficacy was demonstrated in children and adolescents between the ages of 6 and 17 years. Its safety is unknown during pregnancy and lactation. The plant�s pyrrolizidine alkaloids can toxic to the liver and carcinogenic, so only extracts that have specifically removed these compounds should be utilized. Many of the studies on Butterbur utilized the product Petadolex� because it is a standardized extract that has removed these alkaloids of concern. The usual dosage is 50 mg, standardized to 7.5 mg petasin and isopetasin, 2-3x/day with meals (although recent studies show that higher doses appear to be more effective1,2 ). Interestingly, butterbur�s diverse qualities make it useful for other conditions, including seasonal allergic rhinitis, and possibly painful menstrual cramps.

Ginger (Zingiber officinalis)

Ginger root is a commonly used botanical, known to suppress inflammation and platelet aggregation. Little clinical investigation has been performed relative to ginger use in migraine headache, but anecdotal reports and speculation based on its known properties make it a safe and appealing choice for migraine treatment. Some practitioners advise patients with acute migraine to sip a cup of warm ginger tea. Though evidence for this practice is lacking, it is a low-risk, pleasant, and relaxing intervention, and ginger is known to have anti-nausea effects. The most anti-inflammatory support is found in fresh preparations of ginger and in the oil.

Structural Considerations: Holistic

Practitioners of manual medicine seem to achieve success in reducing headache through various techniques such as spinal manipulation, massage, myofascial release, and craniosacral therapy Manual medicine practitioners frequently identify loss of mobility in the cervical and thoracic spine in migraineurs. While many forms of physical medicine seem helpful in shortening the duration and intensity of an episode of migraine, literature support is sparse with regard to manipulation as a modality to prevent recurrent migraine episodes. However, a randomized controlled trial of chiropractic spinal manipulation performed in 2000 revealed a significant improvement in migraine frequency, duration, disability, and medication use in 83 treatment group participants. Tension headache may also respond favorably to these techniques because of the structural component involved in muscular tension. The incidence of migraine in patients with TMJ dysfunction is similar to that in the general population, whereas the incidence of tension headache in patients with TMJ dysfunction is much higher than in the general population. Craniosacral therapy is a very gentle manipulative technique that may also be safely attempted with migraine.

Mind-Body Health: Holistic

There are few things more insulting than to be told by a medical professional to �Just reduce your stress.� Though the total load of stress experienced by an individual can be reduced through paring down unnecessary obligations, many everyday life stressors are unavoidable and cannot be simply eradicated. Thus, the answer to reducing stress for unavoidable contributors lies in two important areas: enhancing physical and mental resilience to stress, and modifying the emotional response to stress.

A multitude of programs to reduce the impact of stress on our physical and emotional well-being are rapidly becoming mainstream. For example, mindfulness meditation programs by Jon KabatZinn, PhD and many others are being offered to communities by hospitals around the country. This technique is simple to perform and has demonstrated positive outcomes in heart disease, chronic pain, psoriasis, hypertension, anxiety, and headaches. Breathwork and guided imagery techniques are likewise effective in producing a relaxation response and helping patients to feel more empowered about their health.

Biofeedback and relaxation training have been used with mixed success for migraine headache. Thermal biofeedback uses the temperature of the hands to help the individual learn that inducing the relaxation response will raise hand temperature and facilitate other positive physiologic changes in the body. Learning how to take more active control over the body may reduce headache frequency and severity. The effectiveness of biofeedback and relaxation training in reducing the frequency and severity of migraine headaches has been the subject of dozens of clinical studies, revealing that these techniques can be as effective as medication for headache prevention, without the adverse effects. Other relevant modalities to consider in this light include cognitive behavioral therapy, neurolinguistic programming, hypnosis, transcutaneous electrical nerve stimulation, and laser therapy.

Exercise should not be overlooked as a modality helpful in migraine headache. Thirty-six patients with migraine who exercised 3x/week for 30 minutes over six weeks experienced significant improvement in headache outcomes. Pre-exercise beta-endorphin levels in these individuals were inversely proportional to the degree of improvement in their post-exercise headache parameters. All patients should understand the critical importance of exercise on general health.

Acupuncture: Holistic

A discussion about a holistic integrative approach to migraine headache would be incomplete without acupuncture, which is an effective treatment modality for acute and recurrent migraine. A qualified/licensed practitioner of Traditional Chinese Medicine or a physician trained in medical acupuncture should be consulted.

Holistic: Summary Of Recommendations

  • Since initiators of migraine headache may be cumulative, identify and avoid them when possible. Consider the basic areas of dysfunction bulleted on the first page of this syllabus.
  • The incidence of food intolerance is high in patients with migraine headache; consider a comprehensive elimination diet for four to six weeks, during which time the following foods are eliminated: dairy products, gluten-containing grains, eggs, peanuts, coffee/black tea, soft drinks, alcohol, chocolate, corn, soy, citrus fruits, shellfish, and all processed foods. Careful reintroduction of one food at a time, no more often than every 48 hours, may help identify a food culprit. Meticulous recording of foods reintroduced is necessary. Most patients feel improved vitality during the elimination phase. Foods that clearly produce migraine (or other) symptoms should be avoided or used on a rotation schedule of not more than once every four days. If multiple foods introduced back into the diet seem to produce migraine headache, consider the possibility of altered intestinal permeability (leaky gut syndrome).
  • Consider the following supplements (Consult a qualified practitioner for advice):
  • Magnesium glycinate: 200-800 mg/day in divided doses (decrease to tolerance if diarrhea occurs)
  • Vitamin B6 (pyridoxine): 50-75 mg/day, balanced with B complex o 5-HTP: 100-300 mg 2x/day, with or without food, if clinically appropriate
  • Vitamin B2 (riboflavin): 400 mg/day, balanced with B complex
  • Coenzyme Q10: 150 mg/day
  • Consider hormonal therapies
  • Trial of melatonin: 0.3-3 mg at bedtime
  • Trial of progesterone or estradiol, carefully individualized, under medical supervision.
  • Botanical medicines
  • Feverfew: 25-100 mg 2x/day with meals
  • Butterbur: 50 mg 2-3x/day with meals
  • Ginger root
  • Fresh ginger, approximately 10 gm/day (6 mm slice)
  • Dried ginger, 500 mg 4x/day
  • Extract standardized to contain 20% gingerol and shogaol; 100-200 mg 3x/day for prevention, and 200 mg every 2 hours (up to 6 x/day) for acute migraine
  • Manual medicine may be helpful for some individuals.
  • Acupuncture
  • Mind-body support
  • Thermal biofeedback
  • Read The Relaxation Response by Herbert Benson, MD
  • Mindfulness meditation programs
  • Centering prayer
  • Breathwork
  • Guided imagery
  • Yoga, tai chi, qi gong, etc.
  • Many other modalities to consider!

Conclusion: Holistic Medicine

Patients will often request a more natural and self directed approach to health care. The recommendations above are typically very safe to implement, and are often welcomed by migraine sufferers. A practitioner with an integrative holistic focus will investigate an extensive array of predisposing factors to determine the underlying features most likely involved in a given individual�s condition. In this way, we treat the individual, rather than his or her diagnosis, and we will generate a favorable impact upon his/her overall health in the process.

Chiropractic Care & Headaches

�American Board of Integrative Holistic Medicine. All rights reserved.