ClickCease
+1-915-850-0900 [email protected]
Select Page

Health

Back Clinic Health Team. The level of functional and metabolic efficiency of a living organism. In humans, it is the ability of individuals or communities to adapt and self-manage when facing physical, mental, psychological, and social changes in an environment. Dr.Alex Jimenez D.C., C.C.S.T, a clinical pain doctor who uses cutting-edge therapies and rehabilitation procedures focused on total health, strength training, and complete conditioning. We take a global functional fitness treatment approach to regain complete functional health. Dr. Jimenez presents articles both from his own experience and from a variety of sources that pertain to a healthy lifestyle or general health issues. I have spent over 30+ years researching and testing methods with thousands of patients and understand what truly works. We strive to create fitness and better the body through researched methods and total health programs. These programs and methods are natural and use the body’s own ability to achieve improvement goals, rather than introducing harmful chemicals, controversial hormone replacement, surgery, or addictive drugs. As a result, individuals live a fulfilled life with more energy, a positive attitude, better sleep, less pain, proper body weight, and education on maintaining this way of life.

Causation and Chiropractic Care: Addressing Pain and Mobility

Causation and Chiropractic Care: Addressing Pain and Mobility

Uncover the importance of causation with chiropractic care in proving the connection between trauma and injuries in personal injury cases.

Abstract

Causation is the essential legal and medical bridge connecting an incident—such as a motor vehicle collision, slip-and-fall, or workplace trauma—to the injuries that justify recovery in personal injury claims. Without clear proof that the event caused or materially contributed to the harm, even severe pain and disability may not support full compensation. In my practice at Injury Medical Clinic PA in El Paso, Texas, I have observed for more than three decades that musculoskeletal injuries from trauma rarely exist in isolation. They disrupt joint mechanics, muscle balance, nerve signaling, and overall function, often leading to secondary problems such as chronic pain, reduced mobility, sleep disruption, and compensatory strain in distant body regions. Chiropractic care addresses these issues directly by restoring joint motion, reducing abnormal afferent input to the nervous system, decreasing local inflammation, and facilitating the body’s natural healing processes. When integrated with medical oversight from Dr. Maria Guadalupe Cardenas, MD, board-certified in Internal Medicine, functional medicine principles, targeted rehabilitation, and non-surgical regenerative options, this approach provides both clinical recovery and the objective documentation needed to establish medical causation. This educational post explains what causation means in personal injury, what chiropractic care is, how the two work together, why chiropractic care reduces musculoskeletal injuries and their comorbidities, and how an integrative team model supports durable, non-surgical recovery. Drawing on current evidence from leading researchers and my clinical observations, the goal is to help readers understand the journey from injury event to functional restoration.

Understanding Causation in Personal Injury Cases

Causation is the legal and medical requirement that links a defendant’s negligent or wrongful act to the plaintiff’s injury. Courts and insurance evaluators require evidence that the incident was both the actual cause and the proximate cause of the harm. Actual cause, often called the “but-for” test, asks whether the injury would have occurred but for the incident. Proximate cause, or legal cause, asks whether the harm was a reasonably foreseeable result of the conduct and whether the connection is close enough to justify liability. In practice, medical causation is established to a reasonable degree of medical probability—more likely than not—that the trauma caused or substantially contributed to the diagnosed condition.

The Bradford Hill criteria, originally proposed in 1965 by epidemiologist Sir Austin Bradford Hill, provide a structured way to evaluate whether an observed association is likely causal. These include strength of association, consistency across studies, specificity, temporality (the exposure must precede the outcome), biological gradient or dose-response relationship, biological plausibility, coherence with existing knowledge, experimental evidence, and analogy. In musculoskeletal personal injury, temporality is especially important: symptoms that begin or clearly worsen after a documented collision, with a mechanism consistent with known tissue tolerances, support causation. Medical records that capture the mechanism of injury, the timing of symptom onset, objective findings such as restricted range of motion, positive orthopedic tests, and imaging that correlates with clinical presentation become central evidence. Expert testimony from treating providers who have examined the patient, reviewed the history, and followed the response to treatment carries significant weight because causation opinions are inherent in clinical care.

In personal injury, delayed symptom onset does not automatically defeat causation. Soft-tissue injuries such as strains, sprains, and disc injuries can produce progressive inflammation and pain that peaks hours or days later as chemical mediators accumulate and protective muscle guarding develops. Thorough documentation of the incident details, the patient’s position and restraint use, the direction of impact, and the progressive clinical findings helps distinguish trauma-related injury from pre-existing conditions. When alternative explanations are less likely, and treatment produces measurable improvement consistent with the injury’s expected natural history, the causal link is strengthened.

What Is Chiropractic Care

Chiropractic care is a licensed healthcare profession focused on diagnosing, treating, and preventing disorders of the neuromusculoskeletal system, particularly those involving the spine and extremities. Doctors of Chiropractic are trained to evaluate joint dysfunction, soft-tissue injury, and related functional impairments, then deliver manual therapies—most commonly spinal and extremity adjustments or mobilizations—along with rehabilitative exercise, soft-tissue techniques, and patient education. The core clinical goal is to restore normal joint motion, reduce abnormal mechanical stress, modulate pain signaling, and support the body’s capacity for recovery without reliance on surgery or long-term pharmaceuticals when those interventions can be avoided or delayed.

Modern, evidence-based chiropractic practice is grounded in biomechanics and neurophysiology rather than older theories of “vertebral subluxation” as a cause of systemic disease. High-velocity, low-amplitude thrusts and graded mobilizations stimulate mechanoreceptors in joint capsules, ligaments, and muscle spindles. This afferent barrage can produce short-term changes in segmental spinal excitability, alter descending pain-modulatory pathways, and reduce local muscle hypertonicity. Clinical practice guidelines from multiple organizations support spinal manipulative therapy as part of multimodal care for acute, subacute, and chronic low back pain, neck pain, and certain headache presentations. Systematic reviews and randomized trials have shown reductions in pain intensity and improved function, particularly when chiropractic care is combined with exercise and education.

In the personal injury setting, chiropractic care is often the patient’s first and most continuous contact after trauma. Early evaluation identifies red flags that require imaging or medical referral, establishes objective baseline measures, and begins conservative management while the inflammatory phase of healing is still active. Because many musculoskeletal injuries from collisions or falls are graded sprains and strains rather than fractures or complete ruptures, non-surgical restoration of motion and load-sharing is both clinically appropriate and consistent with the principle of beginning with the least invasive effective option.

How Chiropractic Care Works Hand in Hand with Causation in Personal Injury

Chiropractic care and the proof of causation reinforce each other in several practical ways. First, the initial examination captures the patient’s mechanism of injury in their own words and correlates it with clinical findings. A restrained driver who reports neck pain after a rear-end impact, who demonstrates restricted cervical rotation, and who exhibits positive orthopedic tests for soft-tissue strain supplies the temporality and biological plausibility elements of causation analysis. Subsequent visits document the recovery trajectory: decreasing pain scores, increasing measurable range of motion, improved strength, and reduced functional limitations. These serial observations create a clear timeline that is difficult to dismiss as unrelated to the incident.

Second, chiropractic providers routinely record objective data—goniometric measurements, muscle testing, orthopedic special tests, and postural observations—that can be compared over time. When these findings improve in parallel with the expected phases of tissue healing (inflammatory, proliferative, and remodeling), the records support the conclusion that the trauma produced a treatable injury whose resolution is consistent with the care provided. Third, chiropractic documentation often includes the absence of prior similar symptoms or the clear aggravation of pre-existing conditions. In my clinical experience, patients who had stable, low-level back or neck complaints before a collision frequently report a distinct increase in intensity, new radiation of pain, or new functional loss after the event. Documenting that distinction is essential when defense argues the current symptoms are merely the natural progression of degenerative changes.

Finally, the treating chiropractor’s ongoing relationship with the patient supplies continuity that a one-time independent medical examination cannot match. When the same provider observes both the acute presentation and the response to care, the opinion that the incident caused or materially contributed to the injury rests on direct clinical observation rather than retrospective chart review alone. Courts and juries give substantial weight to this contemporaneous evidence, especially when it is consistent across chiropractic and medical notes within the same clinic.

Physiological Underpinnings of Chiropractic Care for Musculoskeletal Injuries

Spinal and extremity joints that lose normal motion after trauma generate continuous abnormal input from mechanoreceptors and nociceptors. This input can facilitate segmental spinal cord neurons, expand pain receptive fields, and maintain protective muscle co-contraction that further restricts motion. High-velocity, low-amplitude manipulation produces a brief, high-frequency burst of discharge from muscle spindle primary afferents and other dynamically sensitive receptors. Animal and human studies show that this afferent volley can reduce the excitability of dorsal horn neurons involved in pain transmission and modulate descending inhibitory pathways originating in the brainstem and higher centers.

Beyond neural effects, restoring joint motion improves local circulation and reduces concentrations of inflammatory mediators in peri-articular tissues. When synovial fluid redistributes and capsular tension normalizes, the chemical environment that sustains peripheral sensitization improves. Soft-tissue techniques used with joint mobilization address myofascial trigger points and adhesions that develop from muscle guarding. Together, these changes reduce the mechanical and chemical drivers of pain, allowing patients to resume more normal movement patterns that further promote healing.

For disc-related injuries, controlled distraction or flexion-distraction techniques can reduce intradiscal pressure and may improve nutrient diffusion into the avascular disc. Combined with core stabilization exercise, this strategy aims to restore load-sharing among the spine’s passive (ligaments and discs), active (muscles), and neural control subsystems. Clinical observations in my practice confirm that patients who regain segmental motion early and then progress through graded loading recover function more reliably than those who remain immobilized or who rely solely on passive modalities.

How Chiropractic Care Reduces Musculoskeletal Injuries and Their Comorbidities

Musculoskeletal injuries from trauma commonly produce a cascade of secondary problems. Restricted motion leads to muscle atrophy and altered recruitment patterns. Persistent nociceptive input can contribute to central sensitization, sleep fragmentation, and reduced physical activity. Reduced activity then worsens cardiovascular fitness, glycemic control, and mood. Chiropractic care interrupts this cascade at several points.

Randomized trials in active-duty military personnel have shown that adding chiropractic care to usual medical management produces moderate improvements in low-back-pain intensity and disability at six weeks, along with higher patient satisfaction and lower self-reported pain-medication use. Observational studies of older Medicare beneficiaries with chronic low back pain and multiple comorbidities found lower overall costs and lower rates of subsequent surgery among those who received chiropractic manipulative treatment. Systematic reviews support spinal manipulative therapy as part of multimodal care for neck pain and cervicogenic headache, with reductions in both pain and associated disability.

In personal injury populations, the comorbidities I most frequently observe are compensatory shoulder or hip strain from altered gait or posture, tension-type or cervicogenic headache secondary to upper cervical dysfunction, and sleep disruption that prolongs recovery. By restoring cervical and lumbar motion, reducing muscle hypertonicity, and enabling earlier return to graded activity, chiropractic care decreases the likelihood that these secondary problems become entrenched. Patients who recover segmental mobility and core endurance report better tolerance for work and daily activities, which in turn supports mental health and reduces the risk of prolonged opioid exposure.

Integrative Chiropractic Care in Non-Surgical Treatments

Non-surgical management of traumatic musculoskeletal injury is most effective when mechanical, neurological, and systemic factors are addressed together. Integrative chiropractic care combines joint mobilization or manipulation with rehabilitative exercise, soft-tissue therapy, nutritional support for tissue repair, and, when indicated, regenerative options such as platelet-rich plasma under appropriate medical direction. The reasoning is straightforward: restoring motion reduces abnormal loading and afferent drive, while progressive loading stimulates collagen remodeling and motor-pattern retraining. Functional medicine evaluation can identify co-factors—such as vitamin D insufficiency, sleep apnea, or inflammatory dietary patterns—that slow healing even when local mechanics are improved.

Spinal decompression is used when imaging and clinical findings indicate disc-related nerve compression; controlled traction reduces intradiscal pressure and can create a window for nutrient exchange and symptom relief, allowing patients to participate more fully in active rehabilitation. Soft-tissue techniques and instrument-assisted mobilization address adhesions that limit excursion. Acupuncture or electroacupuncture is sometimes added for additional pain modulation via endogenous opioid and non-opioid pathways. The plan adjusts throughout based on the healing phase and the patient’s response, with medical oversight ensuring red-flag conditions are identified and any necessary imaging, lab evaluation, or referral occurs promptly.

The Multidisciplinary Team at Injury Medical Clinic PA and the Role of Dr. Maria Guadalupe Cardenas

At Injury Medical Clinic PA (Mission Plaza Injury Medical Clinic) in El Paso, Texas, a coordinated team delivers care under dual clinical leadership. I provide chiropractic evaluation and treatment together with nurse-practitioner-level medical assessment. Dr. Maria Guadalupe Cardenas, MD, Board Certified in Internal Medicine, NPI #1164426749, Texas MD License #J2933, serves as Medical Director and Collaborative Physician. With more than 40 years of experience as an internist, Dr. Cardenas provides physician-level oversight for complex cases, reviews systemic medical issues that may affect recovery, and collaborates on treatment plans that require medical decision-making beyond the scope of chiropractic or advanced-practice nursing alone.

This structure is common in integrative injury clinics. The chiropractor focuses on joint mechanics, soft-tissue function, and progressive rehabilitation. The internist evaluates comorbidities such as hypertension, diabetes, or inflammatory conditions that can influence healing, coordinates any necessary imaging or specialty referral, and ensures that documentation meets both clinical and medicolegal standards. Physical therapists, massage therapists, and additional nurse practitioners contribute specific modalities and exercise progression. The result is a single, coherent record that captures the mechanism of injury, objective findings, response to care, and medical correlation—precisely the elements needed to support causation analysis.

Patients benefit because decisions consider both mechanical and systemic perspectives. When a patient with pre-existing diabetes sustains a disc injury, for example, glycemic control is optimized alongside spinal decompression and core training so that microvascular factors do not impede soft-tissue healing. When sleep disruption or mood changes appear, we address them rather than ignore them. The collaborative model therefore supports both clinical recovery and the clear, consistent documentation that personal injury claims require.

Clinical Observations from Dr. Alexander Jimenez

In more than three decades of practice in El Paso, I have repeatedly observed that the patients who recover most completely are those whose care begins with a precise description of the mechanism of injury and whose treatment plans are adjusted according to measured progress rather than a fixed schedule. A mid-20s heavy-labor worker who sustained neck and low-back injuries in a collision recovered approximately 80 percent of function over nineteen weeks, and then experienced a second collision, requiring careful re-evaluation of both the new trauma and the residual deficits from the first event. The integrated record—chiropractic measurements of motion and strength together with medical assessment of systemic factors—allowed the team to distinguish the effects of each incident and to modify the plan accordingly.

I have also noted that delayed symptom onset is common after low-speed collisions when the head is rotated or when the patient is looking over the shoulder. Soft-tissue strain and facet irritation can cause progressive inflammation that peaks 1 to 3 days later. Early documentation of the exact body position and the progressive clinical findings has proven essential when causation is later questioned. Patients who receive early restoration of joint motion, soft-tissue care, and graded activity consistently report better sleep, fewer compensatory pains, and faster return to work than those whose care is limited to passive modalities or prolonged rest.

These observations align with the broader literature: multimodal care that includes spinal manipulative therapy produces meaningful reductions in pain and disability, and contemporaneous records from the treating team provide the strongest evidence of both the injury and its causal relationship to the incident.

Why Specific Techniques and Protocols Are Used

Spinal and extremity adjustments are used because restricted joint motion after trauma generates ongoing abnormal afferent input that facilitates pain and maintains muscle guarding. By restoring motion, the technique reduces that input and allows more normal movement patterns to re-emerge. The reasoning is both biomechanical—normalization of load distribution—and neurophysiological—modulation of segmental and descending inhibitory pathways.

Spinal decompression is selected when clinical and imaging findings indicate disc-related compression because controlled distraction can lower intradiscal pressure and may improve fluid exchange. It is paired with stabilization exercise so the temporary pressure reduction is followed by improved muscular support.

Soft-tissue techniques and therapeutic exercise are included because muscle guarding and trigger points develop secondary to joint dysfunction and nociceptive drive. Addressing them directly reduces local ischemia and referred pain, while progressive loading stimulates collagen alignment during remodeling. The protocol includes medical oversight and functional-medicine evaluation because systemic factors—inflammation, nutrient status, sleep, and comorbidities—modulate tissue repair. Optimizing these factors increases the probability that local mechanical improvements translate into durable functional gains.

The protocol is individualized throughout according to injury grade, healing phase, and measured response. Conservative care continues when progress is documented; imaging or specialty referral occurs when red flags appear, or expected improvement does not occur. This reasoned, stepwise approach supports both clinical recovery and the clear causal narrative required in personal injury documentation.

Conclusion

Causation in personal injury is established by demonstrating that an incident more likely than not caused or substantially contributed to the diagnosed musculoskeletal injuries and their functional consequences. Chiropractic care supports this process by providing early, continuous, objective documentation of the mechanism, findings, and treatment response while restoring joint motion, modulating pain signaling, and facilitating tissue healing. When delivered within an integrative model that includes medical direction from an experienced internist such as Dr. Maria Guadalupe Cardenas, functional-medicine principles, and progressive rehabilitation, the approach reduces both the primary injury and the secondary comorbidities that commonly prolong disability. The physiological rationale is grounded in current neurophysiological and biomechanical research, and clinical results in practice align with published trials showing improved pain, function, and reduced reliance on more invasive interventions. Readers seeking recovery after trauma are encouraged to pursue care that addresses both the mechanical and systemic dimensions of injury and that produces the clear, contemporaneous records needed to support both healing and the proof of causation.

References

Hill, A. B. (1965). The environment and disease: Association or causation? Proceedings of the Royal Society of Medicine, 58(5), 295–300. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1898525/

Goertz, C. M., Long, C. R., Vining, R. D., Pohlman, K. A., Walter, J., & Colter, I. (2018). Effect of usual medical care plus chiropractic care vs usual medical care alone on pain and disability among US service members with low back pain: A comparative effectiveness clinical trial. JAMA Network Open, 1(1), e180105. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2680417

Weeks, W. B., Leininger, B., Whedon, J. M., Lurie, J. D., Tosteson, T. D., Swenson, R., O’Malley, A. J., & Goertz, C. M. (2016). The association between use of chiropractic care and costs of care among older Medicare patients with chronic low back pain and multiple comorbidities. Journal of Manipulative and Physiological Therapeutics, 39(2), 63–75. https://www.jmptonline.org/article/S0161-4754(16)00007-5/abstract

Pickar, J. G. (2002). Neurophysiological effects of spinal manipulation. The Spine Journal, 2(5), 357–371. https://www.sciencedirect.com/science/article/abs/pii/S152994300200400X

Gevers-Montoro, C., Provencher, B., Descarreaux, M., Ortega de Mues, A., & Piché, M. (2021). Neurophysiological mechanisms of chiropractic spinal manipulation for spine pain. European Journal of Pain, 25(7), 1429–1448. https://doi.org/10.1002/ejp.1773

Côté, P., Hartvigsen, J., Axén, I., Leboeuf-Yde, C., Corso, M., Shearer, H., Wong, J., Marchand, A. A., Cassidy, J. D., French, S., Kawchuk, G. N., Mior, S., Poulsen, E., Srbely, J., Ammendolia, C., Blanchette, M. A., Busse, J. W., Bussières, A., Cancelliere, C., … Yu, H. (2021). The global summit on the efficacy and effectiveness of spinal manipulative therapy for the prevention and treatment of non-musculoskeletal disorders: A systematic review of the literature. Chiropractic & Manual Therapies, 29, 8. https://doi.org/10.1186/s12998-021-00362-9

SEO Tags

causation personal injury, chiropractic care personal injury, medical causation Bradford Hill, integrative chiropractic El Paso, non-surgical musculoskeletal injury treatment, Dr Alex Jimenez DC APRN FNP-BC, Dr Maria Guadalupe Cardenas MD, Injury Medical Clinic PA El Paso, spinal manipulation neurophysiology, whiplash recovery chiropractic, low back pain evidence-based care, personal injury documentation, multidisciplinary injury clinic Texas

Testosterone and Androgen Physiology in Women: Insights

Testosterone and Androgen Physiology in Women: Insights

Testosterone and Androgen Physiology in Women: Subcutaneous Injections in Coordinated Care

Abstract: Testosterone is a normal hormone in women. The ovaries, adrenal glands, and many local tissues help make and use it. Levels fall slowly with age, not all at once at menopause. A single blood test rarely proves deficiency. The strongest research support for testosterone therapy in women is for distressing low sexual desire after menopause, after other causes are checked. Subcutaneous injections can provide steadier levels in some studied groups, but evidence in women is thinner and remains off-label. Integrative chiropractic care does not replace medical decisions about hormones. It can help patients gain pain relief, better mobility, and improved sleep while the medical team keeps treatment coordinated and safe.

Testosterone and Androgen Physiology in Women: Insights

Testosterone is a female hormone

Androgens are often called male hormones. That label is incomplete. Testosterone is the main circulating active androgen and a normal part of female biology. Women keep lower amounts than men—typically 10 to 20 times lower—but those amounts still guide important physical and metabolic functions (Cleveland Clinic, n.d.; Davis & Wahlin-Jacobsen, 2015). For much of adult life, a woman’s circulating testosterone is higher than her circulating estradiol (Davis & Wahlin-Jacobsen, 2015).

Testosterone works in two ways:

  • Directly, on androgen receptors in muscle, bone, brain, fat, skin, and sexual tissues
  • Indirectly, when local enzymes turn it into estradiol or into the stronger androgen dihydrotestosterone (DHT)

These pathways help explain effects on sexual function, tissue upkeep, and metabolism even when blood levels look low (Davis & Wahlin-Jacobsen, 2015; Labrie et al., 2017).

Where women’s androgens come from

Women do not rely on one gland. Production is shared.

  • The ovaries release some testosterone and larger amounts of precursors
  • The adrenal glands release DHEA and DHEA-sulfate (DHEAS), a large precursor pool
  • Peripheral tissues—fat, skin, muscle, and other organs—convert those precursors into the small amounts of hormone they need

This last step is called intracrinology. Many tissues make the hormone they need on site and then break it down before much of it returns to the blood (Labrie et al., 2017). A blood testosterone result is only the visible tip of a larger local system.

Enzymes in tissues can convert DHEA to testosterone, make DHT, or turn testosterone into estradiol. The same precursor can become an androgen in one tissue and an estrogen in another. Local enzymes, not just the lab, decide the outcome (Labrie et al., 2017; Schiffer et al., 2018).

A long slope, not a sudden cliff

Estradiol falls sharply at menopause. Androgens do not. DHEA and DHEAS begin to fall from about the third decade of life and may be down by roughly 60% by menopause (Davis & Wahlin-Jacobsen, 2015). A woman in her forties is already below her own earlier peak.

Midlife data measured by mass spectrometry found median testosterone falling from about 0.56 nmol/L in the early forties to about 0.42 nmol/L in the late fifties, with a low point near ages 58–59. In women of similar age, testosterone did not differ by menopausal stage. Natural menopause itself is not a stand-alone reason to administer testosterone (Wang et al., 2025).

Two exceptions matter:

  • Surgical menopause (both ovaries removed) cuts the ovarian share at once
  • Premature ovarian insufficiency creates an earlier deficit than the usual age-related slope (Davison et al., 2005; Soman et al., 2019)

The postmenopausal ovary can also continue to produce some testosterone for years after estradiol output has collapsed (Davis & Wahlin-Jacobsen, 2015).

Why one lab number rarely settles the question

Measuring female testosterone is challenging. Routine immunoassays were built for the much higher male range. Liquid chromatography–tandem mass spectrometry (LC-MS/MS) is more reliable. Most circulating testosterone is bound to sex hormone-binding globulin (SHBG), so free hormone can change when SHBG changes even if total testosterone stays the same (Rosner & Vesper, 2010).

What moves SHBG—and the free fraction:

  • Oral estrogen and high thyroid hormone tend to raise SHBG and lower free testosterone
  • Obesity and insulin resistance tend to lower SHBG and raise free testosterone
  • Androgen excess, including polycystic ovary syndrome (also discussed as polyendocrine metabolic ovarian syndrome, or PMOS), also lowers SHBG (Luo et al., 2024; Teede et al., 2023)

Low SHBG is also a metabolic clue and has been linked to higher diabetes risk in women (Ding et al., 2009). Guidelines do not diagnose androgen deficiency based on a single value. A level is a baseline and a safety check, not the whole diagnosis (Davis et al., 2019; Parish et al., 2021).

What the evidence supports—and what it does not

The clearest evidence is in sexual function. Higher endogenous testosterone tracks modestly with better desire (Maseroli & Vignozzi, 2022). In randomized trials, testosterone improved desire, arousal, orgasm, pleasure, and satisfaction and reduced sexual distress in postmenopausal women with low desire (Islam et al., 2019).

Androgen receptors sit in bone, muscle, fat, vessels, and the brain. That map is real. This is not the same as a proven benefit. Trials supporting sexual-function gains have not firmly shown better body composition, bone, mood, or cognition to the same standard (Davis, 2025; Islam et al., 2019). Some tissue effects may also come from local conversion to estradiol.

Too much androgen is the other problem: acne, unwanted hair, cycle changes, and higher cardiometabolic risk in PMOS/PCOS (Teede et al., 2023). Risk can appear at both ends of the female range (Luo et al., 2024). The target is a physiologic band, not “more is better.”

International groups have not endorsed a broad “female androgen deficiency syndrome,” because no blood cutoff cleanly separates symptomatic women from normal variation (Davis et al., 2019; Wierman et al., 2014). The one consensus indication is hypoactive sexual desire disorder (HSDD) in postmenopausal women—low desire that causes distress—after other causes are addressed (Parish et al., 2021). There is still no FDA-approved testosterone product for women in the United States. Prescribing remains off-label, and long-term heart and breast data in women are limited (Islam et al., 2019; Panay et al., 2024).

What subcutaneous testosterone injections are

A subcutaneous (SubQ) injection places testosterone into the fatty layer under the skin, usually in the abdomen or thigh, with a short, thin needle. An intramuscular (IM) injection goes deeper into muscle.

In men and in some gender-affirming care settings, weekly SubQ testosterone esters can reach therapeutic levels with smaller peaks and troughs, less pain, and easier self-use than some IM schedules (Figueiredo et al., 2022). That data should not be copied wholesale onto women.

  • Women need much smaller doses
  • Female physiologic ranges are far lower
  • Randomized evidence in women is mainly transdermal, not SubQ (Davis et al., 2019)
  • Guidelines do not establish a subcutaneous route for women and do not endorse compounded products as first-line (Parish et al., 2021)

If a clinician considers low-dose SubQ testosterone cypionate in oil, it is an individualized, off-label choice. The goal is to keep exposure within the premenopausal physiologic range, monitor for acne, hair changes, voice changes, or metabolic shifts, and document informed consent (Davis et al., 2019; Jimenez, 2026b). If this route is used at all, start low, titrate to symptoms plus labs, use the same assay method over time, and do not treat menopause itself as an automatic indication (Wang et al., 2025). Compounded prefilled low-dose syringes are not FDA-approved for women. They are a delivery tool, not proof that therapy is indicated.

What patients gain from integrative chiropractic care

Hormone questions and musculoskeletal problems often show up together. Women with midlife androgen decline may also notice joint stiffness, slower recovery, fatigue, and poorer sleep (Davis, 2025; Jimenez, 2026a). After an auto accident or work injury, neck pain, low-back pain, and delayed stiffness can stack on top of that picture.

Integrative chiropractic care does not replace a hormone plan. It focuses on what the patient can gain:

  • Pain relief through restored joint motion and less mechanical strain
  • Improved mobility so walking, lifting, work, driving, and home tasks feel more possible
  • Better sleep when night pain, muscle tightness, and poor recovery ease
  • Stronger return to activity after crashes, work strain, or chronic back and neck pain

Chiropractic adjustments, soft-tissue care, and rehabilitation are non-invasive and drug-free. Used well, they can lower the chance that pain is managed only with long-term medication or rushed toward surgery. That is a simple safety idea: first do no harm, then add only what the person needs.

Integrative care also means working with the patient’s existing medical team. Supervising clinicians handle hormone dosing, lab review, and medication decisions. Chiropractic care adds movement, recovery, and function so the whole plan stays coordinated rather than split into separate silos.

How the El Paso team works together

At Injury Medical Clinic PA in El Paso, Texas, Dr. Alexander Jimenez, DC, APRN, FNP-BC, CFMP, IFMCP, ATN, CCST, provides chiropractic care, functional-medicine framing, and dual-licensed nurse-practitioner evaluation. In clinical observation, he describes testosterone as one part of a wider plan, not a stand-alone energy shot. He notes that women have androgen receptors across muscle, bone, and brain; that levels often fall by the mid-forties compared with the mid-twenties; and that low-dose, monitored strategies may support libido, energy, and musculoskeletal integrity in selected patients when labs, symptoms, and safety checks line up (Jimenez, 2026a, 2026c). He also stresses that SubQ use in women is not the same as male testosterone replacement and should not be sold as routine wellness care (Jimenez, 2026b). More clinical notes appear on dralexjimenez.com and LinkedIn.

Off-label hormone decisions need medical oversight. Dr. Maria Guadalupe Cardenas, MD, board-certified in internal medicine (NPI #1164426749, Texas MD License #J2933), has more than 40 years of experience as an internist. She serves as Medical Director and Collaborative Physician at Injury Medical Clinic PA. This multidisciplinary setup is common in integrative and injury clinics: an MD provides medical direction while a chiropractor delivers hands-on spinal and rehabilitation care.

Together, the team can connect:

  • Medical screening and comorbidity review
  • Chiropractic care for pain, mobility, and sleep-related musculoskeletal strain
  • Functional medicine review of sleep, gut, thyroid, iron, and metabolic drivers that also change SHBG
  • Personal injury care and rehabilitation after crashes, work injuries, or delayed symptoms
  • Clear communication with the patient’s other physicians so care stays safe and well coordinated

Putting the pieces together

A careful visit starts with the story—desire, distress, energy, sleep, pain, injuries, medicines, and surgery—then an exam and labs used as a baseline, not a verdict. Other causes come first: relationship strain, depression, pain, vaginal dryness, thyroid disease, and medication effects. For many women, that means no testosterone. For some postmenopausal women with HSDD, a carefully dosed, monitored plan may be discussed. If SubQ is chosen, it stays small, measured, and reversible while chiropractic care rebuilds the capacity to move and recover.

Testosterone is a normal female hormone made in more than one place and used inside many tissues. It declines on a long slope. Blood tests tell only part of the story. The honest evidence base is strongest for distressed low sexual desire after menopause, not for menopause itself. Subcutaneous injections can offer steady delivery in other groups, but in women they remain an individualized, off-label option that must stay within a physiologic range.

The safest frame is coordinated care: medical direction for hormone decisions, chiropractic and rehabilitation for pain relief, mobility, and sleep, and a plan that prefers non-invasive options when they can help a person function without adding avoidable risk.

“Your body works as a unified system—your hormones directly dictate how well your spinal muscles heal and protect your joints. You don’t have to navigate chronic discomfort or confusing hormonal shifts alone; reach out to our team today to learn how safe, monitored subcutaneous protocols can be seamlessly coordinated with your physical care to help you live without limits.”


References

Cleveland Clinic. (n.d.). What are androgens?

Davis, S. R. (2025). Not just sex: Other roles for testosterone in women. Climacteric, 28(4), 373–376.

Davis, S. R., Baber, R., Panay, N., Bitzer, J., Perez, S. C., Islam, R. M., Kaunitz, A. M., Kingsberg, S. A., Lambrinoudaki, I., Liu, J., Parish, S. J., Pinkerton, J., Rymer, J., Simon, J. A., Vignozzi, L., & Wierman, M. E. (2019). Global consensus position statement on the use of testosterone therapy for women. The Journal of Clinical Endocrinology & Metabolism, 104(10), 4660–4666.

Davis, S. R., & Wahlin-Jacobsen, S. (2015). Testosterone in women—the clinical significance. The Lancet Diabetes & Endocrinology, 3(12), 980–992.

Davison, S. L., Bell, R., Donath, S., Montalto, J. G., & Davis, S. R. (2005). Androgen levels in adult females: Changes with age, menopause, and oophorectomy. The Journal of Clinical Endocrinology & Metabolism, 90(7), 3847–3853.

Ding, E. L., Song, Y., Manson, J. E., Hunter, D. J., Lee, C. C., Rifai, N., Buring, J. E., Gaziano, J. M., & Liu, S. (2009). Sex hormone-binding globulin and risk of type 2 diabetes in women and men. The New England Journal of Medicine, 361(12), 1152–1163.

Figueiredo, M. G., Rodrigues, V. P., & Sande-Lee, S. (2022). Testosterone therapy with subcutaneous injections: A safe, practical, and reasonable option. Journal of the Endocrine Society.

Islam, R. M., Bell, R. J., Green, S., Page, M. J., & Davis, S. R. (2019). Safety and efficacy of testosterone for women: A systematic review and meta-analysis of randomised controlled trial data. The Lancet Diabetes & Endocrinology, 7(10), 754–766.

Jimenez, A. (2026a). Hormone optimization explained for women’s health. Dr. Alex Jimenez.

Jimenez, A. (2026b). Subcutaneous testosterone for hormone balance therapy guide. Dr. Alex Jimenez.

Jimenez, A. (2026c). Integrative hormone therapy and chiropractic care insights. Dr. Alex Jimenez.

Labrie, F., Martel, C., Bélanger, A., & Pelletier, G. (2017). Androgens in women are essentially made from DHEA in each peripheral tissue according to intracrinology. The Journal of Steroid Biochemistry and Molecular Biology, 168, 9–18.

Luo, X., Wang, Y., Wang, L., Shen, Y., & Ren, M. (2024). Association between female androgen levels, metabolic syndrome, and cardiovascular disease: An NHANES analysis (2013–2016). International Journal of Women’s Health, 16, 2087–2101.

Maseroli, E., & Vignozzi, L. (2022). Are endogenous androgens linked to female sexual function? A systematic review and meta-analysis. The Journal of Sexual Medicine, 19(4), 553–568.

News-Medical. (n.d.). The role of testosterone in women’s health.

Panay, N., Ang, S. B., Cheshire, R., Goldstein, S. R., Maki, P., & Nappi, R. E. (2024). Menopause and MHT in 2024: Addressing the key controversies—An International Menopause Society white paper. Climacteric, 27(5), 441–457.

Parish, S. J., Simon, J. A., Davis, S. R., Giraldi, A., Goldstein, I., Goldstein, S. W., Kim, N. N., Kingsberg, S. A., Morgentaler, A., Nappi, R. E., Park, K., Stuenkel, C. A., Traish, A. M., & Vignozzi, L. (2021). International Society for the Study of Women’s Sexual Health clinical practice guideline for the use of systemic testosterone for hypoactive sexual desire disorder in women. The Journal of Sexual Medicine, 18(5), 849–867.

Rosner, W., & Vesper, H. (2010). Toward excellence in testosterone testing: A consensus statement. The Journal of Clinical Endocrinology & Metabolism, 95(10), 4542–4548.

Schiffer, L., Arlt, W., & Storbeck, K. H. (2018). Intracrine androgen biosynthesis, metabolism and action revisited. Molecular and Cellular Endocrinology, 465, 4–26.

Soman, M., Huang, L. C., Cai, W. H., Xu, J. B., Chen, J. Y., He, R. K., Ruan, H. C., Xu, X. R., Qian, Z. D., & Zhu, X. M. (2019). Serum androgen profiles in women with premature ovarian insufficiency: A systematic review and meta-analysis. Menopause, 26(1), 78–93.

Teede, H. J., Tay, C. T., Laven, J. J. E., Dokras, A., Moran, L. J., Piltonen, T. T., Costello, M. F., Boivin, J., Redman, L. M., Boyle, J. A., Norman, R. J., Mousa, A., & Joham, A. E. (2023). Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome. The Journal of Clinical Endocrinology & Metabolism, 108(10), 2447–2469.

Wang, Y., Islam, R. M., Bond, M., & Davis, S. R. (2025). Testosterone and pre-androgens by age and menopausal stage at midlife: Findings from a cross-sectional study. eBioMedicine, 121, 105972.

Wierman, M. E., Arlt, W., Basson, R., Davis, S. R., Miller, K. K., Murad, M. H., Rosner, W., & Santoro, N. (2014). Androgen therapy in women: A reappraisal. An Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 99(10), 3489–3510.

SubQ Testosterone for Women: Exploring Treatment Options

SubQ Testosterone for Women: Exploring Treatment Options

SubQ Testosterone for Women: Dosing, Monitoring, and Muscle Support

Abstract: Testosterone is not a male-only hormone. Women make more of it than estrogen by weight throughout much of their adult lives, and those levels decline with age. The strongest research supports low-dose therapy for postmenopausal women who have distressing low sexual desire. Subcutaneous injections place a modest, consistent amount of the hormone into the fat under the skin so blood levels can return to a typical female range. This article explains how that route works, who may be a candidate, how clinicians monitor the dose, how muscle and bone support movement, and how integrative chiropractic care in El Paso can work alongside medical oversight to treat the spine, joints, and hormones as one system.

SubQ Testosterone for Women: Exploring Treatment Options

Why Women Need Testosterone, Too

Testosterone is not just a leftover male hormone; women produce it in significant amounts. Across most of adult life, a woman’s ovaries and adrenal glands produce more testosterone than estrogen by mass. That output falls with age and drops further after the ovaries are removed (Davis et al., 2019; Hatzilabrou, 2025).

When levels sit at the low end of a woman’s own range, some women notice a persistent, unwanted loss of desire. That problem has a name: hypoactive sexual desire disorder, or HSDD. Distress is the key. A quiet fade that does not bother her is not the same as a loss that troubles her every day (Davis et al., 2019; Parish et al., 2021).

Pooled randomized trials in thousands of women show that restoring testosterone into the normal premenopausal range can improve desire, arousal, orgasm, pleasure, and satisfaction, and can lower sexual distress. The gains are real and consistent, but they are moderate, not magic, and a strong placebo response is part of the picture (Islam et al., 2019; Hatzilabrou, 2025).

What Subcutaneous Injections Actually Do

A subcutaneous (SubQ) injection delivers medicine into the fatty layer just under the skin, not deep into muscle. Typical sites are the abdomen or outer thigh. The needle is short and thin. Oil-based testosterone—often testosterone cypionate—then seeps out slowly, which can keep blood levels steadier than a large intramuscular shot (FOLX Health, n.d.; Hone Health, 2024).

Think of it as a small, measured drip rather than a flood. Women need far less than men, often about one-tenth of a typical male dose. Clinics that use weekly SubQ cypionate often start in a low milligram range and then adjust to a lab result, not to a feeling (Highland Longevity, n.d.; Hone Health Help Center, n.d.).

Keep these route facts in view:

  • Most high-quality trials in women used patches, creams, or gels, not weekly shots (Hatzilabrou, 2025).
  • One older implant study in women was positive for desire and bone density, but fixed pellets can overshoot the female range and cannot be turned down once placed (Hatzilabrou, 2025).
  • No published milligram conversion exists from a 300-microgram patch to a SubQ syringe. The honest method is to dose to a measured blood level (Davis et al., 2019; Hatzilabrou, 2025).
  • No testosterone product is FDA-approved for women in the United States. Use is off-label and requires informed consent (Cedars-Sinai, n.d.; Parish et al., 2021).

Some compounding programs offer low-concentration, prefilled single-dose syringes of testosterone cypionate in MCT oil for SubQ use. A ready syringe does not change the rules. Exposure still has to stay inside the female physiologic band (Hatzilabrou, 2025; Medivant Health, n.d.).

The Target Is Narrow, Not “Bigger Is Better”

A healthy young woman typically has a total testosterone level of about 15 to 46 ng/dL. That is a sliver of the male range. The job of therapy is to land inside that band and stay there (Hatzilabrou, 2025; Braunstein et al., 2011).

Pushing past the ceiling does not add extra desire. It shows up as acne, extra facial hair, scalp thinning, voice change, and other androgen effects (Islam et al., 2019; Parish et al., 2021).

A practical path looks like this:

  • Confirm HSDD with real distress after other causes are checked.
  • Draw a baseline total testosterone with a sensitive LC-MS/MS test, not a routine immunoassay built for men (Rosner et al., 2007).
  • Start low.
  • Recheck the level and symptoms at about 8-12 weeks.
  • Assess benefit at 3 to 6 months. If distressing low desire has not improved, stop rather than climb (Davis et al., 2019; Parish et al., 2021).

Baseline testosterone does not diagnose HSDD. It is a safety tool once treatment starts (Hatzilabrou, 2025).

Two problems are often mistaken for low desire. Antidepressants, especially SSRIs, can blunt desire on their own. Genitourinary syndrome of menopause—dryness, atrophy, and pain with sex—can look like low desire when the real issue is pain. Local estrogen, not a systemic androgen, is built for that problem (Parish et al., 2021; Cedars-Sinai, n.d.).

What the Body May Gain Beyond Desire

Sexual function is the outcome with the firmest trial support. Other claims need a quieter voice.

Muscle and strength. Testosterone helps muscle protein building in both sexes. Some women report better lean mass and training response when testosterone levels return to a mid-physiologic range. Large pooled trial data in women have not shown a robust body-composition effect at the low doses used for HSDD, so frame this as possible support, not a guarantee (Islam et al., 2019; Hatzilabrou, 2025).

Bone. One small two-year implant trial found faster gains in spine, hip, and total-body density when testosterone was added to estradiol. Guidelines still do not list bone as an approved reason to prescribe it because the study was small and not designed to prevent fractures (Davis et al., 1995; Wierman et al., 2014).

Energy and mood. Early and smaller studies sometimes showed better well-being. Dedicated trials and systematic reviews have been mixed or null for mood, fatigue, and cognition. Societies do not endorse testosterone as a general menopause tonic (Islam et al., 2019; Dichtel et al., 2020; Cedars-Sinai, n.d.).

Red blood cells. Testosterone can raise red-cell production. That is a monitoring issue at higher exposure, not a reason to treat ordinary anemia in women (Hatzilabrou, 2025).

For the spine and joints, even modest improvements in muscle and bone health matter. Stronger hip and core muscles help the pelvis stay level. Better bone quality supports the vertebrae that a chiropractor adjusts. After a car crash, a work injury, or months of guarded movement, patients who can train without crashing energy often stay in rehab longer (Jimenez, n.d.-a).

Safety, Side Effects, and the Long View

Short- and medium-term data at physiologic doses are generally reassuring for the day-to-day effects clinicians watch: acne, extra hair, and oily skin. Those effects are usually dose-related and often fade if the dose is cut (Islam et al., 2019; Nachtigall et al., 2011).

What is missing is the long view. Adequately powered trials have not settled cardiovascular and breast outcomes over many years. That gap—not a proven harm signal—is a main reason no female product has been approved (Hatzilabrou, 2025; Cedars-Sinai, n.d.).

Therapy is not for pregnancy, breastfeeding, or people trying to conceive. Women with high baseline heart or breast-cancer risk need an especially clear shared decision (Hone Health Help Center, n.d.; Parish et al., 2021).

How Integrative Chiropractic Care Fits

Hormones don’t exist apart from the skeleton. Low energy, weaker muscles, and slower recovery make spinal joints stiffer and make rehab after an auto accident harder. Integrative care treats that loop instead of handing a woman only a syringe or only an adjustment.

At Injury Medical Clinic PA in El Paso, Texas (11860 Vista Del Sol, Suite 128), we build care as a team. Dr. Alexander Jimenez, DC, APRN, FNP-BC, CCST, CFMP, IFMCP, ATN, is dual-licensed as a chiropractor and board-certified family nurse practitioner. His clinical writing stresses that female testosterone use is not a copy of male replacement: the best randomized evidence is still transdermal; SubQ use in women is an individualized off-label choice, and the goal is a physiologic range with a stop rule if desire does not improve (Jimenez, n.d.-b).

Dr. Maria Guadalupe Cardenas, MD, is his internist and is board-certified in internal medicine (NPI #1164426749, Texas MD License #J2933), with more than 40 years of experience. She serves as medical director and collaborative physician. In this model, the internist provides medical direction, reviews labs and overall health, and helps keep advanced or off-label therapies within safe bounds. The chiropractor restores joint motion, posture, and neuromuscular control. Functional medicine looks at sleep, gut health, thyroid, iron, and medications that can blunt desire. Personal injury and rehabilitation services rebuild strength after crashes, falls, and sports injuries, so a hormone plan isn’t asked to do the work of a weak core or an unhealed disc (Jimenez, n.d.-a).

That mix is common in integrated injury clinics: an MD directs the medical lane while a DC treats the mechanical lane. For a woman on low-dose testosterone, the practical payoff is simple. If the muscles around the spine hold better, adjustments last longer. When bone and lean mass improve, fall risk and “I feel fragile” complaints may ease. If pain and sleep improve, desire often has a clearer path—without pretending testosterone is a cure for every menopausal complaint.

A Clear Path Forward

Testosterone treatment in women is neither a wellness trend nor a male protocol scaled down by guesswork. It is a narrow, evidence-backed option for postmenopausal HSDD with distress, given at a female physiologic dose, watched with the right lab, and stopped if it does not help.

Subcutaneous injections can deliver that modest, steady dose into the fat under the skin. They ask for discipline: start low, measure, stay inside the range, and pair the hormone with the rest of the care—local vaginal treatment when dryness is the real problem, medication review when an antidepressant is the real problem, and hands-on musculoskeletal care when the spine and hips cannot carry the load.

In El Paso, that whole-person path is the point of the collaboration between Dr. Cardenas’s internal medicine oversight and Dr. Jimenez’s chiropractic, functional medicine, and injury rehab work. The hormone is only one tool. The goal is a woman who can move, recover, and feel like herself again.


References

Braunstein, G. D., Reitz, R. E., Buch, A., Schaefer, D., & Caulfield, M. P. (2011). Testosterone reference ranges in normally cycling healthy premenopausal women. The Journal of Sexual Medicine, 8(10), 2924–2934.

Cedars-Sinai. (n.d.). Testosterone therapy for women.

Davis, S. R., Baber, R., Panay, N., Bitzer, J., Perez, S. C., Nappi, R. E., Nijland, E., Simon, J., Vignozzi, L., & Wierman, M. E. (2019). Global consensus position statement on the use of testosterone therapy for women. The Journal of Clinical Endocrinology & Metabolism, 104(10), 4660–4666.

Davis, S. R., McCloud, P., Strauss, B. J., & Burger, H. (1995). Testosterone enhances estradiol’s effects on postmenopausal bone density and sexuality. Maturitas, 21(3), 227–236.

Dichtel, L. E., Carpenter, L. L., Nyer, M., Mischoulon, D., Kim, S., Cusin, C., Pedrelli, P., Fisher, L., Papakostas, G. I., & Fava, M. (2020). Low-dose testosterone augmentation for antidepressant-resistant major depressive disorder in women: An 8-week randomized placebo-controlled study. American Journal of Psychiatry, 177(10), 965–973.

FOLX Health. (n.d.). HRT subcutaneous vs. intramuscular injections.

Hatzilabrou, T. A. (2025). Testosterone therapy in women [White paper]. Worldborne Medical / Medivant Healthcare.

Highland Longevity. (n.d.). Women’s testosterone dosing guide.

Hone Health. (2024). Injectable testosterone cypionate for women.

Hone Health Help Center. (n.d.). Testosterone cypionate injection for women: Risks & benefits.

Islam, R. M., Bell, R. J., Green, S., Page, M. J., & Davis, S. R. (2019). Safety and efficacy of testosterone for women: A systematic review and meta-analysis of randomised controlled trial data. The Lancet Diabetes & Endocrinology, 7(10), 754–766.

Jimenez, A. (n.d.-a). Injury specialists. Injury Medical Clinic PA.

Jimenez, A. (n.d.-b). Subcutaneous testosterone for hormone balance therapy guide. Injury Medical Clinic PA.

Medivant Health. (n.d.). Andrenyx.

Nachtigall, L., Casson, P., Lucas, J., Schofield, V., Melson, C., & Simon, J. A. (2011). Safety and tolerability of testosterone patch therapy for up to 4 years in surgically menopausal women receiving oral or transdermal oestrogen. Gynecological Endocrinology, 27(1), 39–48.

Parish, S. J., Simon, J. A., Davis, S. R., Giraldi, A., Goldstein, I., Goldstein, S. W., Kim, N. N., Kingsberg, S. A., Morgentaler, A., Nappi, R. E., Park, K., Stuenkel, C. A., Traish, A. M., & Vignozzi, L. (2021). International Society for the Study of Women’s Sexual Health clinical practice guideline for the use of systemic testosterone for hypoactive sexual desire disorder in women. The Journal of Sexual Medicine, 18(5), 849–867.

Rosner, W., Auchus, R. J., Azziz, R., Sluss, P. M., & Raff, H. (2007). Utility, limitations, and pitfalls in measuring testosterone: An Endocrine Society position statement. The Journal of Clinical Endocrinology & Metabolism, 92(2), 405–413.

Wierman, M. E., Arlt, W., Basson, R., Davis, S. R., Miller, K. K., Murad, M. H., Rosner, W., & Santoro, N. (2014). Androgen therapy in women: A reappraisal. An Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 99(10), 3489–3510.

Legal Peptides and Their Role in Medical Care

Legal Peptides and Their Role in Medical Care

Legal Peptides and Integrative Chiropractic Care: A Clear Guide

Abstract

This article explains legal peptide use in plain language. Legal peptide use means giving, making, or prescribing certain short chains of amino acids that regulatory bodies such as the Food and Drug Administration (FDA) have officially approved for medical use. Readers will learn how approved drugs differ from compounded products and research-only chemicals. The article then reviews the New Mexico Board of Nursing’s September 2026 peptide FAQs. It covers a valid patient-provider relationship, telehealth, advertising, nutrition, and muscle care. The last sections show how integrative chiropractors and nurse practitioners work together, and how Dr. Alexander Jimenez, DC, APRN, FNP-BC, and Dr. Maria Guadalupe Cardenas, MD, run that model at Injury Medical Clinic PA in El Paso.

Legal Peptides and Their Role in Medical Care

What Legal Peptide Use Means

Peptides are short chains of amino acids. The body already makes many of them. They act like small messages that can change appetite, hormone release, inflammation, and tissue repair (Findlay, 2026; Vibrant Health of Colorado, 2026).

Legal peptide use means giving, making, or prescribing certain short chains of amino acids that regulatory bodies such as the Food and Drug Administration (FDA) have officially approved for medical use (Findlay, 2026; Peptide Laws, n.d.). In everyday terms, a peptide plan is safer when:

  • A regulator has officially approved that product for medical use.
  • A licensed clinician examines the patient and writes a prescription.
  • Any compounded version follows federal compounding law and state pharmacy rules.
  • The chart shows a reason, informed consent, and follow-up (ByrdAdatto, n.d.; LumaLex Law, n.d.).

Insulin, semaglutide, tirzepatide, tesamorelin, and bremelanotide (PT-141) are examples of peptides with FDA-approved products for specific conditions (Findlay, 2026; DJ Holt Law, 2026). Approval covers a product and its use. It does not make every similar vial on the internet legal.

Approved, Compounded, or Research-Only

FDA-approved medicines have finished clinical trials and manufacturing review. A clinician may use an approved drug off-label when science and judgment support that choice, but the product itself is still an approved drug (DJ Holt Law, 2026; ByrdAdatto, n.d.).

Compounded peptides are custom medicines made for one named patient when the law allows it. They are not FDA-approved. They may differ in formula, stability, and oversight (New Mexico Board of Nursing, 2026). After branded GLP-1 shortages eased, federal policy tightened around copies of those products (DJ Holt Law, 2026; Peptide Laws, n.d.).

Research-only chemicals are often sold as “not for human use.” Popular names include BPC-157, TB-500, and several growth-hormone secretagogues. That label does not make clinical use legal. The FDA treats marketing for human treatment as a drug claim (Findlay, 2026; LumaLex Law, n.d.). Status can also change as compounding committees review bulk substances (DJ Holt Law, 2026).

State boards rarely ban peptides as a whole class. They do ask whether the prescriber stayed in scope, did a real exam, and used a lawful pharmacy (Peptide Journal, 2026; ByrdAdatto, n.d.).

What the New Mexico Board of Nursing Said

In September 2026, the New Mexico Board of Nursing published clinical-practice FAQs on peptide therapies. The Board said the page is guidance, not a legal opinion, and it does not change the Nursing Practice Act (New Mexico Board of Nursing, 2026). The answers still give a clear map.

Key points include:

  • APRNs may prescribe compounded medicines within their population focus and prescriptive authority if they have the education and judgment to do so. The Board uses LACE: licensure, accreditation, certification, and education.
  • GLP-1 medicines are among the most watched peptides because they help and they carry risk.
  • A valid patient-provider relationship must exist before prescribing.
  • A compounded GLP-1 vial must stay patient-specific. It cannot be shared.
  • Pharmacies should be licensed and able to share sterility testing.
  • Patients must be told when a product is compounded rather than a brand-name FDA-approved drug.
  • Reckless prescribing—not peptide use alone—invites discipline (New Mexico Board of Nursing, 2026).

New Mexico grants nurse practitioners full practice authority. Texas generally requires a collaborating physician (Peptide Journal, 2026). The clinical standard still looks the same: exam, reason, consent, monitoring, and a clean pharmacy.

The Exam, Telehealth, and Honest Ads

The Board listed what should happen before GLP-1 or related peptide care starts (New Mexico Board of Nursing, 2026):

  • A health history and a review of current medicines
  • A check for higher-risk problems, such as family medullary thyroid cancer or MEN-2, pancreatitis, gallbladder disease, kidney disease, pregnancy plans, eating disorders, or frailty
  • A physical exam and baseline labs when they are needed
  • Consent that covers benefits, common side effects, serious risks, other options, how long care may last, lifestyle changes, and weight regain after stopping
  • A written plan and later checks of weight, nutrition, tolerance, and dose

Telehealth can be used when the standard of care is still met. A questionnaire alone is not enough. The prescriber must also be licensed in the state where the patient is located (New Mexico Board of Nursing, 2026). Ads must be truthful. Claims of guaranteed weight loss do not meet professional standards. The Federal Trade Commission watches those claims (New Mexico Board of Nursing, 2026). A med-spa name does not change the duty of the person who evaluates and prescribes.

Food and Muscle Still Come First

The Board was clear: medicine is not the whole treatment. Providers should counsel patients on protein, resistance exercise, lean-mass protection, vitamins, and long-term habits. Skipping that work can lead to muscle loss, frailty, and poor results after the drug stops (New Mexico Board of Nursing, 2026). Integrative clinics make the same point. Peptides work best when you address food, sleep, and movement (Nourish House Calls, n.d.; Evolution Integrative Medicine, n.d.).

How Integrative Chiropractic Care Fits

Teams of integrative chiropractors and nurse practitioners (NPs) work together in integrative medical offices. Most of the time, chiropractors do the manual therapies, biomechanics, and structural rehabilitation. Nurse practitioners, on the other hand, conduct clinical evaluations and have the medical authority to prescribe and oversee therapies (ProCredits, n.d.; Jimenez, 2026a). That split protects both the patient and the license.

Chiropractic care links to peptide treatment by making muscles and bones stronger:

  • Adjustments and mobilization restore joint motion and lower mechanical stress on nerves and soft tissue.
  • Better motion lets a person load a tendon, hip, or spine pattern with less guarding.
  • Rehab—easy isometrics, then controlled loading—tells muscle, tendon, and bone to remodel.
  • Protein-forward eating provides the building blocks those tissues need.
  • A legal metabolic peptide, when indicated, may help appetite, blood sugar, and body composition so rehab is easier to finish.
  • Any tissue-support peptide is an add-on to loading, not a replacement for it (El Paso Back Clinic, n.d.; Gruber Chiropractic, n.d.).

Dr. Jimenez has written that peptides should not be sold as a shortcut to grow cartilage, discs, or ligaments. Food cannot unlock a stuck joint. An adjustment cannot replace protein. Each tool has a job (Jimenez, 2026a).

The El Paso Team: Dr. Jimenez and Dr. Cardenas

Injury Medical Clinic PA in El Paso shows how those roles work in daily care. Dr. Alexander Jimenez, DC, APRN, FNP-BC, CCST, CFMP, IFMCP, ATN, is a dual-licensed chiropractor and board-certified family nurse practitioner. He leads conservative care, rehabilitation, functional medicine, and personal-injury documentation (Jimenez, n.d.).

Dr. Maria Guadalupe Cardenas, MD, is board-certified in internal medicine (NPI #1164426749; Texas MD License #J2933). With more than 40 years of experience as an internist, she serves as medical director and collaborative physician. This multidisciplinary setup is common in integrative or injury clinics, where an MD provides medical direction alongside a chiropractor. The team integrates chiropractic care from Dr. Jimenez with medical oversight by Dr. Cardenas, plus functional medicine, personal injury care, rehabilitation, and related services (Jimenez, n.d.; El Paso Back Clinic, n.d.).

A simple path for crash, sports, or chronic back pain recovery looks like this:

  • Map the problem with history, exam, and movement testing.
  • Restore motion with chiropractic and soft-tissue care.
  • Rebuild muscle and bone loading with graded rehab.
  • Address nutrition and metabolic gaps.
  • Add a legal, patient-specific peptide only after the reason, labs, and consent are on the chart.

Clinical Observations on Strength and Recovery

Clinical observations shared by Dr. Jimenez describe peptides as possible signaling helpers, not magic. Progress often looks better when spinal care is paired with inflammation control, body-weight support, protein intake, and sleep (Jimenez, 2026a; El Paso Back Clinic, n.d.). Other clinics describe peptides for recovery, metabolism, gut integrity, sleep, and connective tissue (New Life Physicians, n.d.; RevitalIV, n.d.). Those descriptions are not the same as FDA approval. Patients should ask which product is approved, which is compounded for them alone, and which is still experimental.

Questions to Ask Before Starting

Before any peptide begins, ask four plain questions:

  • Is this an FDA-approved product or a compounded one?
  • Who is the licensed prescriber, and which state does the patient live in?
  • What exam, labs, and follow-up will I receive?
  • How will chiropractic care, exercise, and nutrition work with the medicine?

Boards expect those answers in the record (New Mexico Board of Nursing, 2026; ByrdAdatto, n.d.). Legal peptide use is a medical act. Integrative chiropractic care is a movement and strength act. When a clinic keeps both lines clear, patients build stronger muscles and bones—and, when appropriate, receive carefully chosen peptide support without a gray-market detour.


References

ByrdAdatto. (n.d.). How state laws impact peptides.

DJ Holt Law. (2026). What peptides are legal in the U.S.? Understanding FDA approval, compounding, and the legal gray areas.

El Paso Back Clinic. (n.d.). Integrative peptide science and chiropractic innovations.

El Paso Chiropractic. (n.d.). Peptide chiropractic wellness guide in El Paso.

Evolution Integrative Medicine. (n.d.). Why integrative medicine practitioners are turning to peptide therapy.

Findlay, S. (2026, July 30). Are peptides legal? Everything you want to know. Healthline.

Gruber Chiropractic. (n.d.). Peptide therapy.

Jimenez, A. (n.d.). Injury specialists. Injury Medical Clinic PA.

Jimenez, A. (n.d.). Dr. Alexander Jimenez [LinkedIn profile].

Jimenez, A. (2026a). Peptide therapy, nutrition, and chiropractic care explained. Dr. Alex Jimenez.

LumaLex Law. (n.d.). Peptides.

New Life Physicians. (n.d.). Commonly used peptides.

New Mexico Board of Nursing. (2026, September). Peptide therapies: Clinical practice frequently asked questions.

Nourish House Calls. (n.d.). How functional medicine uses peptides.

Peptide Journal. (2026). Are peptides legal? State-by-state guide.

Peptide Laws. (n.d.). United States peptide laws.

ProCredits. (n.d.). Peptide therapy for chiropractors: Tissue repair and metabolic health.

RevitalIV. (n.d.). Top 5 most popular peptides: What they do.

Vibrant Health of Colorado. (2026, January 23). Peptide therapy: A functional medicine guide.

SubQ Testosterone Injections for Hormone Balance Explained

SubQ Testosterone Injections for Hormone Balance Explained

SubQ Testosterone Injections for Hormone Balance

Abstract
Subcutaneous testosterone injections place hormone therapy in the fat layer just under the skin instead of deep inside a muscle. Men and women can both receive this type of shot when a clinician decides it is appropriate. The smaller needle is often easier to use at home, and weekly levels can stay more even than with a deep muscle shot. This article explains how the method works, how testosterone supports muscle and bone, and how integrative chiropractic care in El Paso can sit beside medical hormone care. It is an option for people who don’t want pellets or a deep intramuscular injection.

SubQ Testosterone Injections for Hormone Balance Explained

What a Subcutaneous Shot Is

A subcutaneous (SubQ) injection goes into the thin layer of fat beneath the skin. Common sites are the belly and the outer thigh. The needle is short and thin. An intramuscular (IM) shot goes deeper into muscle, often the glute or thigh, and usually requires a longer needle.

Both routes can use the same familiar esters, such as testosterone cypionate or enanthate. The medicine is not a brand-new drug. The change is where the oil sits. Fat has less blood flow than muscle, so the hormone often leaves the depot more slowly. Average blood levels can land in a similar place. The shape of the week is often calmer.

For about eighty years, deep muscle injection was simply the habit. In The Quiet Case for the Subcutaneous Needle, Dr. Thomas A. Hatzilabrou, M.D., of Worldborne Medical, makes a narrow claim: move the same ester from muscle to fat, and therapy can become easier to live with without giving up the average level guidelines care about (Hatzilabrou, n.d.).

That claim is about a route, not a brand.

Why the Weekly Curve Matters

The Endocrine Society and the American Urological Association tell clinicians to restore testosterone to a mid-normal range in men who truly need treatment, match the plan to the person, and check labs on a schedule.

Two plans can share the same average and still feel like different weeks. A deep IM shot can spike high, then sag before the next dose. People feel that sag as low energy, low mood, or a crash. Modeling of testosterone enanthate found that SubQ dosing blunts that peak-to-trough swing. The average is the number on the lab report. The swing is the number a person lives in (Hatzilabrou, n.d.; Figueiredo et al., 2022).

A review found SubQ testosterone to be feasible, practical, and reasonable for routine use, with comparable mean levels. A 52-week study of weekly SubQ enanthate found that 92.7% of men were in the target range by week 12, and more than 95% reported no injection-related pain.

One dosing rule matters at every switch visit. A milligram under the skin may not equal a milligram in the muscle. After a change, assess the level and how the person feels. Do not assume syringe-for-syringe equality.

SubQ Testosterone for Men and for Women

Both men and women can receive SubQ testosterone when a licensed clinician chooses that plan. The smaller needle is often more convenient for women and for anyone who prefers not to receive a deep glute injection.

The research is not even, and that honesty belongs here.

  • In men with low testosterone, SubQ shots have produced target-range levels and better comfort than IM.
  • In gender-affirming care, people who switched from IM to SubQ often preferred SubQ, and levels still reached the intended range.
  • In women, no testosterone product is FDA-approved in the United States. Use is off-label. The goal is a physiologic, premenopausal-range level—not a male dose. The strongest randomized evidence in women is still transdermal gel, not injection (Hatzilabrou, n.d.).

So SubQ can be easier as a technique. It is not automatically the best-proven female route. Any plan in women should stay inside a safe female range, with labs to prove it. Start low. Go slow. Watch skin, hair, voice, and mood.

What This Route Wins On

If average exposure is close to a tie, daily life breaks the tie.

  • A short, fine needle is easier to use on your own.
  • Pain and dread before the shot are usually lower.
  • There is no awkward reach to the glute and less concern about the sciatic path.
  • The week can feel steadier.
  • Cost can stay low because the same generic esters are used.
  • There is no skin-to-skin transfer risk like gels and patches.

Needle fear is common. It turns a five-minute task into the one a person keeps putting off. A delayed dose becomes a missed dose. A missed dose becomes “this isn’t working.” An easier shot is not a luxury. It is how long-term care survives.

Safety does not get lighter because the needle is shorter. High red-cell count, fertility changes, prostate checks in men, and androgenic effects in women track with the hormone level, not with “IM versus SubQ.” Monitoring stays the same.

How the Home Shot Is Done

A clinician teaches the first doses. The usual steps are simple:

  • Wash hands. Set out a clean syringe, a short needle (often 25- to 30-gauge and about half an inch), an alcohol wipe, and a sharps container.
  • Choose a clean site on the abdomen or outer thigh. Rotate sites.
  • Pinch a fold of skin. Insert the needle at about a 45-degree angle. Inject slowly.
  • Do not share syringes. Place used needles in a sharps box.

Xyosted is one FDA-cleared weekly auto-injector for men that is used in the abdomen. Some clinics use compounded syringes. The treating clinician still manages the dose, storage, and follow-up.

This method is straightforward for people who don’t want pellet placement or a deep muscle shot. It is still an injection. It is a middle-path option.

What Testosterone Does for the Body

Testosterone helps the body maintain lean muscle, support bone health, recover after strain, and maintain energy and drive. When levels stay too low, people often feel weak, foggy, and slow to bounce back. Stairs feel taller. Rehab after a sprain, a fall, or a car crash lasts longer.

That is the link to musculoskeletal health. Weaker muscles mean less support around the spine, hips, and knees. Joints take more load. Guarding becomes a habit. Sleep and mood often fall with the strength loss.

A steadier hormone curve does not replace exercise or alignment work. It can give muscle and bone a clearer internal signal while those programs run.

How Integrative Chiropractic Care Fits

Hormone therapy works inside the body. Chiropractic care works on the frame that carries the body.

When the spine and pelvis are restricted, muscles stay tight. Joints load on one side. The nervous system stays loud. That mix can blunt the gains people hope to see from hormone care. Integrative chiropractic care aims to restore motion, ease muscle tightness, and improve how the body shares load. Strength work then has a better platform for these gains.

In my clinical observations, patients often report easier hip and low-back mechanics after treatment for spinal and pelvic restrictions alongside other therapies. I have also seen some men do better when large, infrequent depot shots are changed to smaller, more frequent SubQ doses. The mid-cycle crash—fatigue, irritability, a sense that “the shot wore off”—often settles when the curve flattens. Labs still decide the number. The person decides whether the week feels livable (Jimenez, n.d.).

Chiropractic care does not replace testosterone. Testosterone does not replace an adjustment, a rehab plan, or a strength progression. Together they treat the signal and the structure.

The El Paso Team Model

Injury Medical Clinic PA uses a multidisciplinary model. I serve as clinical director, a chiropractor, and a board-certified family nurse practitioner. Dr. Maria Guadalupe Cardenas, MD, is board-certified in internal medicine (NPI #1164426749, Texas MD License #J2933). She has more than 40 years of experience as an internist and serves as medical director and collaborative physician.

This setup is common in integrative and injury clinics. The MD provides medical direction, internal medicine risk review, and hormone oversight. The chiropractic and rehab team addresses alignment, soft tissue, personal injury recovery, and return to work or sport. Functional medicine adds labs, nutrition, sleep, and gut-muscle links so the plan isn’t just a shot.

A person in this model may move through:

  • Medical review of symptoms, medicines, fertility goals, and safety screens
  • Targeted hormone and metabolic labs
  • Chiropractic care for spinal and pelvic mechanics
  • Rehabilitation for strength, balance, and daily demands
  • Nutrition and recovery habits that support hormone work
  • Follow-up labs for testosterone, hematocrit, and PSA when indicated

Main East Side clinic: 11860 Vista Del Sol, Suite 128, El Paso, TX 79936. Office: 915-850-0900 or 915-412-6677.

Who This Option May Suit

SubQ testosterone may be worth a supervised talk when:

  • Labs and symptoms support treatment, and the person can learn a home shot.
  • Deep IM shots cause pain, fear, or missed doses.
  • Pellets feel like too much commitment or are difficult to fine-tune.
  • Gels are messy or raise transfer concerns at home.
  • The goal is a steadier week, not a bigger peak.

It is a poor first choice when fertility is an immediate goal, when there is a prostate or breast cancer concern, when hematocrit is already high, or when a woman needs the route with the strongest female trial data. Those calls belong in the clinic.

Conclusion

The quiet case for the subcutaneous needle is simple. Same ester. Different depot. Comparable average levels for many patients. It’s a shot that most people can keep getting. Pair that with integrative chiropractic care, and the aim isn’t just a better lab printout. The aim is a body that can still move.

This article is educational. The FDA does not review compounded medicines in the same way it reviews approved branded products. The prescribing clinician makes final treatment decisions after a full evaluation.


References

Bhasin, S., Brito, J. P., Cunningham, G. R., Hayes, F. J., Hodis, H. N., Matsumoto, A. M., Snyder, P. J., Swerdloff, R. S., Wu, F. C., & Yialamas, M. A. (2018). Testosterone therapy in men with hypogonadism: An Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 103(5), 1715–1744. https://doi.org/10.1210/jc.2018-00229

Cleveland Clinic. (n.d.). Subcutaneous testosterone injection.

Figueiredo, M. G., Gagliano-Jucá, T., & Basaria, S. (2022). Testosterone therapy with subcutaneous injections: A safe, practical, and reasonable option. The Journal of Clinical Endocrinology & Metabolism, 107(3), 614–626. https://doi.org/10.1210/clinem/dgab772

Hatzilabrou, T. A. (n.d.). The quiet case for the subcutaneous needle [White paper]. Worldborne Medical / Medivant Healthcare.

Jimenez, A. D. (n.d.). Clinical observations on hormone balance, subcutaneous dosing, and integrative chiropractic care. Injury Medical Clinic PA.

Kaminetsky, J. C., McCullough, A., Hwang, K., Jaffe, J. S., Wang, C., & Swerdloff, R. S. (2019). A 52-week study of dose-adjusted subcutaneous testosterone enanthate in oil self-administered via disposable auto-injector. The Journal of Urology, 201(3), 587–594.

Mayo Clinic. (n.d.). Testosterone (intramuscular route, subcutaneous route).

Mulhall, J. P., Trost, L. W., Brannigan, R. E., et al. (2018). Evaluation and management of testosterone deficiency: AUA guideline. The Journal of Urology, 200(2), 423–432.

Optimale. (2024). How to do a subcutaneous testosterone injection.

Spratt, D. I., Stewart, I. I., Savage, C., Craig, W., Spack, N. P., Chandler, D. W., Spratt, L. V., Eimicke, T., & Olshan, J. S. (2017). Subcutaneous injection of testosterone is an effective and preferred alternative to intramuscular injection: Demonstration in female-to-male transgender patients. The Journal of Clinical Endocrinology & Metabolism, 102(7), 2349–2355.

Thimble Health. (n.d.). The hidden cost of needle fear: What healthcare systems overlook.

Integrative Nerve Block and Forehead Lesion Removal Process

Integrative Nerve Block and Forehead Lesion Removal Process

Integrative Nerve Block and Forehead Lesion Removal: A Step-by-Step, Evidence-Based Guide for Patients and Clinicians

Abstract: In this educational post, I walk you through a patient-centered, step-by-step approach to performing a supraorbital and supratrochlear nerve block. This approach helps comfortably remove a small forehead lesion. I present the latest findings from leading researchers on regional anesthesia safety, dosing, and anatomical precision. I also explain how integrative chiropractic care, functional medicine, and medical oversight fit into a modern multidisciplinary practice. You will learn the anatomy of the supraorbital and supratrochlear nerves. Specifically, you will discover why targeted nerve blocks reduce pain with minimal medication. You will also see how we coordinate between internal medicine and chiropractic. You will also learn how we embed rehabilitation, personal injury protocols, and functional strategies into the patient’s care plan at Injury Medical Clinic PA in El Paso, Texas.

Integrative Nerve Block and Forehead Lesion Removal Process

About Our Integrative Care Team

I am Dr. Alex Jimenez, DC, APRN, FNP-BC, CFMP, IFMCP, ATN, CCST. I practice at Injury Medical Clinic PA (Mission Plaza Injury Medical Clinic) in El Paso, Texas. Dr. Maria Guadalupe Cardenas, MD (Board Certified in Internal Medicine; NPI #1164426749; Texas MD License #J2933) provides medical oversight for modern, integrative musculoskeletal and functional care. Dr. Cardenas has served patients for more than 40 years. As our medical director and collaborative physician, she ensures evidence-based protocols, safety, and continuity of care. Together, we integrate:

  • Chiropractic and manual therapies
  • Medical diagnostics and procedural oversight
  • Functional medicine and systems biology
  • Personal injury care and comprehensive rehabilitation
  • Neuromuscular re-education and ergonomic guidance

Patient-Friendly Roadmap: Forehead Lesion Removal with Precision Nerve Blocks

Today, I describe the process and reasoning behind using a supraorbital and supratrochlear nerve block to comfortably remove a small forehead lesion. This approach minimizes systemic anesthetic exposure. Moreover, it improves pain control at the exact site of care. It allows a calm, efficient procedure.

Why Use Regional Nerve Blocks for Forehead Lesions?

  • Targeted analgesia: Blocking the supraorbital and supratrochlear nerves numbs sensation to the forehead and anterior scalp, producing a painless window for dermatologic procedures.
  • Reduced need for multiple local injections: Instead of repeatedly infiltrating the lesion with anesthetic, a well-placed block numbs the area broadly, lowering the total dose.
  • Faster onset and reliable effect: These superficial branches are accessible, allowing precise anesthesia with low-volume lidocaine, minimizing risk when properly dosed and monitored.
  • Patient comfort and safety: Patients often report lower anxiety and discomfort when they experience quick, controlled analgesia before lesion excision.

The Anatomy: Finding the Target Safely

When planning a forehead block, topographical anatomy and tactile confirmation guide safe technique.

  • Supraorbital nerve: A branch of the ophthalmic division (V1) of the trigeminal nerve, exiting through the supraorbital notch or foramen typically located along the superior orbital rim. Clinically, we palpate just above the eyebrow in a vertical line superior to the center of the pupil. This region carries cutaneous sensation for the mid-forehead and anterior scalp.
  • Supratrochlear nerve: Also from V1, it emerges more medially, above the inner canthus of the eye, and travels along the medial superior orbital rim to supply sensation to the medial forehead and glabellar region.

Understanding this anatomy avoids intravascular injection. It protects the globe and ensures predictable coverage with small volumes.

Step-by-Step: My Clinical Technique

To keep the experience clear and comfortable, I narrate each step. This includes reassuring the patient and dosing safely.

  • Identify landmarks: I palpate the orbital rim and align my injection points:
    • For the supraorbital nerve: just superior to the mid-pupillary line above the eyebrow.
    • For the supratrochlear nerve: at the medial orbital rim above the inner canthus.
  • Prepare the skin: I clean the area thoroughly with alcohol to reduce microbial load.
  • Pinch and stabilize: I gently pinch the skin to control superficial motion and provide mild counter-stimulation that can reduce the perception of needle entry.
  • Needle placement and bone touch: Using a fine-gauge needle, I advance carefully until I lightly contact bone at the superior orbital rim—this tactile stop confirms I am at the correct depth and location without traversing deeper structures.
  • Aspirate and inject safely: After confirming safety, I inject approximately 0.5 mL of lidocaine at each site. With careful technique, I feel a soft bulge against my thumb, confirming adequate local spread near the nerve.
  • Pressure and observation: I apply gentle pressure to limit bruising, monitor for comfort, and reassess coverage.
  • Supplemental local infiltration: If needed for the lesion margins, I add a small ring of local infiltration around the lesion to strengthen anesthesia precisely where the excision will occur.
  • Proceed with the procedure: Once comfort is confirmed, we remove the lesion with attention to aseptic technique and cosmetic incision alignment.

Physiological Basis: How Local Anesthetics Work

  • Sodium channel blockade: Agents like lidocaine enter neuronal membranes and block voltage-gated sodium channels, preventing the depolarization needed to conduct pain signals. This effect is reversible and concentration-dependent.
  • Fiber sensitivity: A-delta and C fibers (pain-transmitting) are more susceptible to blockade than larger motor fibers in this region, which is why sensation is selectively reduced without affecting facial expression.
  • pH and onset: Lidocaine is weakly basic; tissue pH influences ionization and the speed of membrane penetration. Forehead tissue is typically well perfused, supporting consistent onset.
  • Safety margin: Low-volume, superficial injections at the specified sites minimize the risk of intravascular injection and systemic toxicity while providing broad cutaneous anesthesia.

Evidence-Based Considerations: Dosing, Safety, and Monitoring

Contemporary literature highlights practical safeguards and dosing strategies for facial regional blocks:

  • Use the lowest effective dose to achieve sensory blockade, especially in facial procedures with small fields (NYSORA – Peripheral nerve blocks).
  • Aspirate before injection and inject incrementally to reduce the risk of intravascular injection (OpenAnesthesia – Local anesthetic systemic toxicity).
  • Watch for early signs of local anesthetic systemic toxicity (LAST), such as perioral numbness, tinnitus, metallic taste, or CNS changes; keep resuscitation protocols ready if using larger volumes, though small facial blocks carry an extremely low risk (American Society of Regional Anesthesia – LAST checklist).
  • Consider the patient’s comorbidities, medications, and allergies, particularly with internal medicine oversight to ensure whole-person safety.

In our clinic, Dr. Cardenas reviews medical risk factors and ensures that protocols match the patient’s cardiovascular, neurologic, and metabolic profile, integrating internal medicine safeguards into a musculoskeletal and procedural workflow.

Integrative Chiropractic Care: Why It Fits and How We Use It

Chiropractic and functional rehabilitation enhance outcomes before and after minor procedures by optimizing soft tissue tone, posture, and neuromuscular control.

  • Pain modulation and autonomic balance: Gentle cervical and thoracic mobilization, myofascial release, and breathing retraining downregulate sympathetic drive that can heighten pain perception, facilitating smoother procedures and better recovery. Clinical observations in our practice show that patients experience lower tension and improved tolerance when we apply pre-procedural soft tissue techniques judiciously (El Paso Back Clinic – Clinical observations and outcomes).
  • Postural optimization: Forward head posture and frontal muscle overuse can contribute to tension headaches and frontal neuralgia; chiropractic care, ergonomic counseling, and targeted corrective exercise reduce strain on the supraorbital and supratrochlear pathways.
  • Scar management and tissue glide: Following lesion removal, gentle scar mobilization and instrument-assisted soft tissue techniques can improve collagen alignment and prevent restriction of the frontalis and corrugator supercilii fascia, improving comfort and aesthetics.

Integrative care is not just about manual techniques—it is about aligning nervous system regulation, tissue health, and biomechanics to support healing. Paired with precise anesthesia and medical oversight, this approach provides comprehensive, individualized care.

Functional Medicine Integration: Systems-Based Support for Healing

We incorporate functional medicine principles to support tissue repair, immune balance, and skin health:

  • Nutritional support: Adequate protein, vitamin C, zinc, and omega-3 fatty acids support collagen synthesis, angiogenesis, and inflammation resolution. For patients with recurring skin lesions or delayed healing, we assess dietary intake and relevant labs.
  • Glycemic control: Hyperglycemia impairs leukocyte function and collagen cross-linking; optimizing blood sugar improves wound outcomes (Journal of Wound Care – Glycemic control and wound healing).
  • Inflammation mapping: We screen for systemic inflammatory drivers (sleep apnea, gut dysbiosis, chronic stress) and address them with lifestyle, sleep hygiene, and targeted nutraceuticals when appropriate (IFM – Functional medicine approaches to inflammation).

Dr. Cardenas’s internal medicine oversight complements this approach by evaluating comorbidities, adjusting medications, and coordinating lab work to ensure safety and efficacy.

Personal Injury and Rehabilitation: Restoring Function and Confidence

In personal injury cases—such as facial trauma from accidents—regional nerve blocks, minor procedures, and rehabilitation may be combined:

  • Acute care coordination: Medical evaluation to rule out orbital fractures, cranial nerve injuries, or hematomas, followed by precise analgesia and wound management.
  • Rehabilitation pathway: Chiropractic-guided cervical stabilization, vestibular exercises if indicated, and postural retraining to reduce head strain and promote healing without exacerbating neural sensitivity.
  • Return-to-work planning: Ergonomic adjustments, task modification, and graded exposure to activities to prevent flare-ups in the frontal musculature and peri-orbital tissues.

Our clinic focuses on structured progressions and measurable outcomes, ensuring patients move from acute comfort to long-term resilience.

Clinical Observations: What We See in Practice

Drawing from my clinical experience and shared outcomes reported through our channels:

  • Patients frequently report improved tolerance and reduced anxiety with a clear explanation of the nerve block process and gentle stabilization of the injection site.
  • Low-volume, well-placed lidocaine blocks provide reliable anesthesia for forehead lesions without distorting tissue architecture, making cosmetic closures more precise.
  • Integrating soft tissue work and breathing strategies before the procedure helps attenuate anticipatory pain and sympathetic arousal, making the block feel less intense.
  • Post-procedure, patients benefit from simple forehead mobility drills, hydration, and nutritional support to optimize scar remodeling—leading to smoother outcomes and fewer adhesions.
  • In personal injury settings, coupling procedural precision with spine care and functional rehab accelerates return to normal activities and reduces downstream pain syndromes.

For more insights into our integrative protocols and case studies, visit our practice resources:

  • El Paso Back Clinic: https://elpasobackclinic.com/
  • Professional profile: https://www.linkedin.com/in/dralexjimenez/

Our Multidisciplinary Workflow: Safety, Clarity, and Results

Here is how we structure patient care at Injury Medical Clinic PA:

  • Intake and evaluation:
    • Medical history, medications, allergies, and risk factors
    • Anatomic mapping and functional assessment
  • Coordinated plan:
    • Internal medicine oversight by Dr. Cardenas
    • Procedural planning by me with a clear anesthesia strategy
    • Functional and chiropractic support to regulate nervous system tone and improve tissue health
  • Intervention:
    • Pre-procedural soft tissue preparation when appropriate
    • Supraorbital and supratrochlear nerve blocks
    • Lesion removal with attention to aesthetics and aseptic technique
  • Recovery and follow-up:
    • Scar care, nutrition, and movement guidance
    • Ergonomic and postural coaching
    • Monitoring and adjustments coordinated between disciplines

This approach ensures patients receive precise, compassionate care grounded in modern evidence.

Practical Tips for Patients

  • Ask about the plan: Understanding your nerve block and lesion removal steps reduces anxiety and improves your experience.
  • Share your history: Disclose medications, bleeding risks, allergies, and prior reactions to local anesthetics.
  • Prepare for recovery: Plan for gentle care of the site, adequate hydration, and nutrition; avoid picking or excessive facial expressions until sutures are removed.
  • Follow movement and posture guidance: Simple exercises and ergonomic habits support better outcomes and comfort.

Why This Matters: Precision Care with Whole-Person Support

Facial procedures deserve meticulous technique. By combining anatomical precision, low-dose regional anesthesia, and integrative care, we honor both the science and the human experience of healing. With Dr. Cardenas’s medical leadership, evidence-based protocols, and chiropractic-functional rehabilitation, we deliver care that is safe, efficient, and tailored to your needs.

Key Takeaways

  • Supraorbital and supratrochlear nerve blocks provide targeted, efficient analgesia for forehead lesion removal.
  • Low-volume lidocaine with careful anatomical technique enhances safety and cosmetic outcomes.
  • Integrative chiropractic and functional medicine support nervous system regulation, tissue healing, and long-term resilience.
  • Internal medicine oversight ensures comprehensive risk management and continuity of care.
  • A multidisciplinary pathway—from evaluation to rehabilitation—optimizes patient comfort and outcomes.


References

Excision of a Dysplastic Nevus: Step-by-Step Approach

Excision of a Dysplastic Nevus: Step-by-Step Approach

Evidence-Based Excision of a Dysplastic Nevus With Integrative Chiropractic and Functional Medicine Support

Abstract

In this educational post, I guide you through a precise, evidence-based approach to excising a dysplastic nevus with moderate atypia using a pain-free field block technique and narrow margins. I explain my step-by-step method, the anatomical and physiological rationale for local anesthesia and intradermal infiltration, and the clinical decision-making behind margin selection. I also introduce our multidisciplinary model in El Paso, Texas, where I work alongside Dr. Maria Guadalupe Cardenas, MD, our internal medicine medical director, to integrate chiropractic care, functional medicine, personal injury care, rehabilitation, and patient-centered follow-up. Throughout, I present the latest findings from leading dermatologic surgery and pain science researchers, connect these principles to chiropractic neurophysiology, and describe how integrative chiropractic care fits into peri-procedural and long-term outcomes.

Excision of a Dysplastic Nevus: Step-by-Step Approach

Dysplastic Nevus Excision: My First-Person Clinical Approach

I am Dr. Alexander Jimenez, DC, APRN, FNP-BC, CFMP, IFMCP, ATN, CCST. Today, I share my clinical approach to excising a dysplastic nevus with moderate atypia—an area previously shaved and biopsied about one month prior—using narrow but appropriate margins and a meticulous, pain-minimizing anesthesia technique. As the patient sits comfortably, I begin by cleaning the site with alcohol, re-prepping to reduce transient skin flora before marking the excision plan.

  • Clinical context: The original lesion measured approximately 5 by 6 millimeters. With moderate atypia, evidence supports complete removal with narrow margins when severe atypia or melanoma features are absent.
  • Excision planning: I use a sterile template to visualize an elliptical excision, aiming for about 2-millimeter margins around the residual scar. Because the original lesion was 5 x 6 mm, the post-biopsy excision boundary effectively spans about 5 mm beyond the original footprint to ensure complete removal of dysplastic tissue, both visible and microscopic, along the shave plane.

Creating a Pain-Free Field Block: Technique and Rationale

My goal in minor surgical procedures is a pain-free patient experience. I set up a field block—a circumferential ring of local anesthetic that interrupts sensory nerve conduction—so the patient does not feel the needle or the intradermal distension.

  • Anesthetic choice: I use 1% lidocaine with epinephrine.
    • Lidocaine blocks voltage-gated sodium channels on nociceptive and mechanoreceptive fibers, preventing depolarization and conduction of pain signals.
    • Epinephrine induces local vasoconstriction via alpha-adrenergic receptors, prolonging lidocaine’s residence time, reducing bleeding, and minimizing systemic absorption, thereby extending anesthesia duration and improving hemostasis.
  • Spray analgesia: Before needle entry points, I apply a brief vapocoolant “freeze spray.” The cold exposure rapidly reduces superficial nociceptor firing (TRPM8-mediated cold sensing and transient gating of pain fibers), ensuring the patient feels no needle prick. He confirms: “No pain.” This instant desensitization is especially helpful in field blocks that require multiple passes.

Needle Control, Intradermal, and Subcutaneous Delivery: Why It Works

I insert the needle at a chosen point, advance subcutaneously, and inject as I withdraw. Before exiting the skin, I rotate the bevel and repeat on the opposite side. This “inject-on-withdrawal” method creates an even distribution of anesthetic parallel to dermal nerve plexuses.

  • Physiological basis:
    • The dermis contains a dense network of free nerve endings and mechanoreceptors. Intradermal distension with anesthetic rapidly silences A-delta and C-fiber nociceptors via sodium channel blockade.
    • Subcutaneous infiltration saturates the tissue beneath the lesion, interrupting deeper cutaneous nerve branches that feed the operative field.
  • Technique advantages:
    • By threading the needle just past midline and injecting on withdrawal, a visible wheal forms—a sign of intradermal spread.
    • Slightly bending a longer needle allows steering to contour around the template. This helps me remain just outside the marked ellipse, preventing anesthetic pooling in the incision path while fully covering perilesional innervation.
    • Multiple entry points may be necessary for large or anatomically curved sites. With cooling spray and prior subcutaneous saturation, new entry points remain pain-free.

The patient confirms repeatedly: no pain. This validates that the circumferential anesthetic fence is intact and effective.

Margin Selection for Moderate Atypia: Evidence-Based Considerations

A dysplastic nevus with moderate atypia warrants complete excision, but the margin need not be wide if there is no severe atypia or melanoma in situ. Contemporary studies suggest that 2 mm clinical margins often achieve histologic clearance for moderate atypia, particularly when initial shave biopsy delineated architecture and ruled out more aggressive pathology (Kittler et al., 2020; Swetter et al., 2019).

  • Why narrow margins:
    • Preserve healthy tissue and reduce scarring while achieving oncologic adequacy for moderate atypia.
    • Epinephrine-assisted hemostasis reduces bleeding and improves visibility, allowing precise adherence to planned margins.
  • Post-excision pathology:
    • We send the specimen for histologic assessment to confirm clear margins and exclude residual atypia. If margins are positive or close, we discuss re-excision based on the pathologist’s recommendations and the patient’s goals.

Step-by-Step Workflow: From Prep to Incision

  • Second prep: I re-clean the site and confirm sterile field integrity.
  • Template marking: I trace an ellipse aligned with skin tension lines (Langer lines) to enhance cosmetic outcomes and minimize wound tension.
  • Field block completion: Intradermal wheals surround the template; subcutaneous anesthesia saturates the bed beneath the lesion.
  • Patient check-in: I ask about sensation; he reports no pain.
  • Incision and removal: With a sharp blade, I incise along the outside of the template, dissect through the dermis and minimal subcutis to remove the lesion and scar bed en bloc. I maintain hemostasis with epinephrine and use meticulous cautery only when appropriate for the site.
  • Layered closure: Where needed, I approximate with deep absorbable sutures to reduce tension, then close the epidermis with fine non-absorbable sutures aligned to natural creases. This supports rapid healing and improved cosmesis.

Integrative Chiropractic Care in Dermatologic Procedures: Why It Matters

While excising a skin lesion may seem purely dermatologic, integrative chiropractic care supports peri-procedural comfort, autonomic regulation, and recovery. At Injury Medical Clinic PA (Mission Plaza Injury Medical Clinic) in El Paso, I collaborate closely with Dr. Maria Guadalupe Cardenas, MD (Board Certified Internal Medicine; NPI #1164426749; Texas License #J2933). Our model leverages chiropractic neurophysiology, functional medicine, and internal medicine oversight to optimize patient outcomes.

  • Chiropractic neurophysiology:
    • Gentle cervical and thoracic mobility work can reduce sympathetic overactivity and anxiety, thereby lowering perceived pain via descending inhibitory pathways (periaqueductal gray modulation).
    • Soft tissue techniques around the shoulder girdle and thoracic cage relieve myofascial tension that can amplify cutaneous pain through central sensitization.
  • Autonomic balance:
    • Breathing mechanics, rib cage mobility, and vagal tone optimization help stabilize heart rate and blood pressure during minor procedures. Patients report better comfort and less discomfort from injections when sympathetic tone is moderated.
  • Functional ergonomics:
    • Post-procedure, appropriate postures and scapular mechanics reduce strain on healing sites in the back, shoulder, or trunk areas, decreasing shear forces across the incision and promoting better scar formation.

Internal Medicine Oversight: Safety, Risks, and Comorbidities

Dr. Cardenas provides medical direction and co-management for patients with complex medical histories. Together, we tailor anesthesia choices, wound plans, and follow-up based on comorbidities.

  • Hypertension and cardiovascular disease:
    • Epinephrine in lidocaine is generally safe for small dermatologic fields, but we confirm medication lists (beta-blockers, MAO inhibitors) and assess cardiovascular stability. Internal medicine oversight ensures risk stratification and informed consent aligned with the patient’s health status.
  • Diabetes and wound healing:
    • Glycemic control is vital to prevent infection and optimize collagen synthesis and cross-linking in the wound. We coordinate glucose monitoring and provide nutrition guidance consistent with functional medicine principles that support wound healing (adequate protein, vitamin C, and zinc).
  • Anticoagulants and antiplatelets:
    • For patients on warfarin, DOACs, or aspirin, we plan hemostasis strategies, pressure dressings, and post-op monitoring. Most dermatologic excisions proceed without stopping therapy, but Dr. Cardenas ensures that decisions align with evidence and safety.

Functional Medicine and Nutritional Support for Skin Healing

As a Certified Functional Medicine Practitioner (CFMP, IFMCP), I incorporate nutritional and lifestyle strategies to enhance skin repair.

  • Nutrient optimization:
    • Protein targets (1.2–1.6 g/kg/day in older adults during recovery) support fibroblast activity and collagen deposition.
    • Vitamin C and zinc are essential cofactors in collagen hydroxylation and DNA synthesis; deficiencies prolong healing time.
    • Omega-3 fatty acids can modulate inflammatory cytokines, promoting resolutive healing without impairing necessary inflammatory phases.
  • Glycemic control and inflammation:
    • Stable blood sugar reduces advanced glycation end-products that stiffen collagen and impair tensile strength of healing tissue.
  • Sleep and stress:
    • Adequate sleep supports growth hormone and tissue repair, while stress reduction techniques blunt cortisol’s catabolic effects on skin.

Personal Injury Care Integration: Biomechanics and Scar Protection

In personal injury cases, excision sites often lie across regions of high biomechanical load. Our integrative chiropractic and rehabilitation approach minimizes scar widening and pain flares.

  • Biomechanics:
    • Assess regional movement patterns to reduce shear across the healing incision.
    • Educate on movement strategies—log-rolling, hip hinge, and scapular setting—to protect the site in the first 1–2 weeks.
  • Myofascial release:
    • Gentle, indirect techniques adjacent to the excision (not on the wound) decompress fascial layers that, if tight, can pull on the scar and provoke pain.
  • Graded activity:
    • As collagen matures (weeks 3–6), we introduce light isometrics and, later, controlled mobility to align collagen fibers along lines of stress and improve scar pliability.

Rehabilitation and Scar Care: Practical Steps

Post-procedural rehabilitation supports durable, cosmetically pleasing outcomes.

  • Wound care basics:
    • Keep the area clean and protected for the first 24–48 hours; petrolatum-based occlusion maintains moisture and accelerates re-epithelialization.
  • Scar modulation:
    • Silicone sheets or gels reduce hypertrophic scarring by regulating hydration and fibroblast activity.
    • Gentle massage after complete epithelialization (usually after suture removal) remodels scar tissue, improving mobility and sensation.
  • Sun protection:
    • UV exposure can cause hyperpigmented scars; broad-spectrum SPF 30+ prevents cosmetic discoloration and protects collagen integrity.

Collaborative Model at Injury Medical Clinic PA: Roles and Workflow

Our El Paso clinic exemplifies integrative care, common in injury and functional medicine settings, where an MD provides medical direction alongside a chiropractor. Dr. Cardenas, MD, serves as the medical director and collaborative physician, and I lead integrative chiropractic and functional care.

  • Pre-procedure:
    • Medical review: Dr. Cardenas assesses comorbidities, medications, and risk factors.
    • Chiropractic preparation: I provide autonomic regulation techniques and positioning strategies to enhance comfort and reduce nociception.
  • Procedure:
    • Evidence-based anesthesia and excision: I perform a field block and precise excision, with hemostasis and ongoing patient communication.
  • Post-procedure:
    • Follow-up: Internal medicine oversight ensures safe healing. Functional medicine guidance supports nutrition and lifestyle modifications.
    • Rehabilitation: Chiropractic-directed movement strategies, scar protection, and graded return to activity.

Clinical Observations from Practice: Patient Comfort and Outcomes

Across my clinical work in El Paso, patients often report extraordinarily low pain during our field blocks. As reflected in today’s case, the patient experienced no pain during multiple entries and intradermal distension—exactly the outcome we aim for.

  • Observational pearls:
    • Vapocoolant spray dramatically reduces injection discomfort.
    • Injecting as I withdraw produces an even, predictable anesthetic plane and reduces the need for multiple passes.
    • Steering a longer needle allows me to follow the template contour without excessive repositioning.
    • Dialogue with the patient reduces anxiety, tapping into descending pain modulation, which complements the pharmacologic blockade.

You can learn more about my integrative clinical perspectives and patient-centered techniques at my practice resources:

  • El Paso Back Clinic website: https://elpasobackclinic.com/
  • LinkedIn: https://www.linkedin.com/in/dralexjimenez/

Patient Education and Safety: What to Expect After Excision

  • Normal sensations: Mild tightness or itch as healing progresses; avoid scratching.
  • Red flags: Excessive bleeding, spreading redness, purulent discharge, fever, or severe pain—contact us immediately.
  • Activity:
    • Keep the area dry for the first day unless instructed otherwise.
    • Avoid stretching or heavy lifting that places tension across the excision line until cleared.
  • Follow-up:
    • Suture removal typically occurs within 5–14 days depending on body location and tension.
    • Pathology results guide any additional steps. If margins are clear, we move to standard surveillance; if not, we discuss re-excision.

Latest Research Insights Supporting This Approach

  • Local anesthesia with epinephrine is safe and effective for most dermatologic procedures, enhancing duration and hemostasis without increasing necrosis when used within recommended doses (Krunic et al., 2004; Alam & Dover, 2008).
  • Narrow margins for moderate atypia in dysplastic nevi can be appropriate when clinical-pathologic correlation rules out severe atypia or melanoma (Swetter et al., 2019; Kittler et al., 2020).
  • Vapocoolant sprays reduce injection pain by activating cutaneous cold receptors and transiently inhibiting nociception (Gallagher et al., 2009).
  • Layered closure aligned with tension lines optimizes cosmetic outcome and reduces dehiscence risk (Borges, 1984; Alam & Wrone, 2007).
  • Integrative care models with chiropractic and internal medicine collaboration can improve patient satisfaction, reduce pain, and support functional recovery via autonomic modulation and biomechanical optimization (Goertz et al., 2018; Schneider et al., 2015).

Why Integrative Chiropractic Care Fits in This Treatment Plan

  • Whole-person care: Skin health intersects with systemic physiology—autonomic tone, metabolic status, and biomechanics. Chiropractic and functional medicine address these intersections.
  • Peri-procedural calm: Breathing and gentle mobilization improve patient comfort and experience during minor surgery.
  • Long-term outcomes: Scar integrity and function rely on movement patterns, tissue nutrition, and stress regulation—core areas where chiropractic and functional medicine strategies excel.

Our Commitment to Modern, Evidence-Based, Patient-Centered Care

At Injury Medical Clinic PA, our mission is to provide modern, evidence-based care that respects the patient’s experience, safety, and long-term health. By integrating internal medicine oversight from Dr. Cardenas with chiropractic and functional medicine strategies, we ensure that each procedure—from a simple excision to complex injury rehabilitation—benefits from rigorous science and compassionate execution.


References

Mastodon