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Sciatica

Back Clinic Sciatica Chiropractic Team. Dr. Alex Jimenez organized a variety of article archives associated with sciatica, a common and frequently reported series of symptoms affecting a majority of the population. Sciatica pain can vary widely. It may feel like a mild tingling, dull ache, or burning sensation. In some cases, the pain is severe enough to make a person unable to move. The pain most often occurs on one side.

Sciatica occurs when there is pressure or damage to the sciatic nerve. This nerve starts in the lower back and runs down the back of each leg as it controls the muscles of the back of the knee and lower leg. It also provides sensation to the back of the thigh, part of the lower leg, and the sole of the foot. Dr. Jimenez explains how sciatica and its symptoms can be relieved through the use of chiropractic treatment. For more information, please feel free to contact us at (915) 850-0900 or text to call Dr. Jimenez personally at (915) 540-8444.


Chiropractic for Low Back Pain and Sciatica

Chiropractic for Low Back Pain and Sciatica

Chiropractic Management of Low Back Pain and Low Back-Related Leg Complaints: A Literature Synthesis

 

Chiropractic care is a well-known complementary and alternative treatment option frequently used to diagnose, treat and prevent injuries and conditions of the musculoskeletal and nervous systems. Spinal health issues are among some of the most common reasons people seek chiropractic care, especially for low back pain and sciatica complaints. While there are many different types of treatments available to help improve low back pain and sciatica symptoms, many individuals will often prefer natural treatment options over the use of drugs/medications or surgical interventions. The following research study demonstrates a list of evidence-based chiropractic treatment methods and their effects towards improving a variety of spinal health issues.

 

Abstract

 

  • Objectives: The purpose of this project was to review the literature for the use of spinal manipulation for low back pain (LBP).
  • Methods: Asearch strategymodified fromthe Cochrane Collaboration reviewforLBP was conducted through the following databases: PubMed, Mantis, and the Cochrane Database. Invitations to submit relevant articles were extended to the profession via widely distributed professional news and association media. The Scientific Commission of the Council on Chiropractic Guidelines and Practice Parameters (CCGPP) was charged with developing literature syntheses, organized by anatomical region, to evaluate and report on the evidence base for chiropractic care. This article is the outcome of this charge. As part of the CCGPP process, preliminary drafts of these articles were posted on the CCGPP Web site www.ccgpp.org (2006-8) to allow for an open process and the broadest possible mechanism for stakeholder input.
  • Results: A total of 887 source documents were obtained. Search results were sorted into related topic groups as follows: randomized controlled trials (RCTs) of LBP and manipulation; randomized trials of other interventions for LBP; guidelines; systematic reviews and meta-analyses; basic science; diagnostic-related articles, methodology; cognitive therapy and psychosocial issues; cohort and outcome studies; and others. Each group was subdivided by topic so that team members received approximately equal numbers of articles from each group, chosen randomly for distribution. The team elected to limit consideration in this first iteration to guidelines, systematic reviews, meta-analyses, RCTs, and coh ort studies. This yielded a total of 12 guidelines, 64 RCTs, 13 systematic reviews/meta-analyses, and 11 cohort studies.
  • Conclusions: As much or more evidence exists for the use of spinal manipulation to reduce symptoms and improve function in patients with chronic LBP as for use in acute and subacute LBP. Use of exercise in conjunction with manipulation is likely to speed and improve outcomes as well as minimize episodic recurrence. There was less evidence for the use of manipulation for patients with LBP and radiating leg pain, sciatica, or radiculopathy. (J Manipulative Physiol Ther 2008;31:659-674)
  • Key Indexing Terms: Low Back Pain; Manipulation; Chiropractic; Spine; Sciatica; Radiculopathy; Review, Systematic

 

The Council on Chiropractic Guidelines and Practice Parameters (CCGPP) was formed in 1995 by the Congress of Chiropractic State Associations with assistance from the American Chiropractic Association, Association of Chiropractic Colleges, Council on Chiropractic Education, Federation of Chiropractic Licensing�Boards, Foundation for the Advancement of Chiropractic Sciences, Foundation for Chiropractic Education and Research, International Chiropractors Association, National Association of Chiropractic Attorneys, and the National Institute for Chiropractic Research. The charge to the CCGPP was to create a chiropractic �best practices� document. The Council on Chiropractic Guidelines and Practice Parameters was delegated to examine all existing guidelines, parameters, protocols, and best practices in the United States and other nations in the construction of this document.

 

Toward that end, the Scientific Commission of CCGPP was charged with developing literature syntheses, organized by region (neck, low back, thoracic, upper and lower extremity, soft tissue) and the nonregional categories of nonmusculoskeletal, prevention/health promotion, special populations, subluxation, and diagnostic imaging.

 

The purpose of this work is to provide a balanced interpretation of the literature to identify safe and effective treatment options in the care of patients with low back pain (LBP) and related disorders. This evidence summary is intended to serve as a resource for practitioners to assist them in consideration of various care options for such patients. It is neither a replacement for clinical judgment nor a prescriptive standard of care for individual patients.

 

Image of a chiropractor performing spinal adjustments and manual manipulations for low back pain and sciatica.

 

Methods

 

Process development was guided by experience of commission members with the RAND consensus process, Cochrane collaboration, Agency for Health Care and Policy Research, and published recommendations modified to the needs of the council.

 

Identification and Retrieval

 

The domain for this report is that of LBP and low backrelated leg symptoms. Using surveys of the profession and publications on practice audits, the team selected the topics for review by this iteration.

 

Topics were selected based on the most common disorders seen and most common classifications of treatments used by chiropractors based on the literature. Material for review was obtained through formal hand searches of published literature and of electronic databases, with assistance from a professional chiropractic college librarian. A search strategy was developed, based upon the CochraneWorking Group for Low Back Pain. Randomized controlled trials (RCTs), systematic reviews/meta-analyses, and guidelines published through 2006 were included; all other types of studies were included through 2004. Invitations to submit relevant articles were extended to the profession via widely distributed professional news and association media. Searches focused on guidelines, meta-analyses, systematic reviews, randomized clinical trials, cohort studies, and case series.

 

Evaluation

 

Standardized and validated instruments used by the Scottish Intercollegiate Guidelines Network were used to evaluate RCTs and systematic reviews. For guidelines, the Appraisal of Guidelines for Research and Evaluation instrument was used. A standardized method for grading the strength of the evidence was used, as summarized in Figure 1. Each team’s multidisciplinary panel conducted the review and evaluation of the evidence.

 

Figure 1 Summary of Grading of Strength of Evidence

 

Search results were sorted into related topic groups as follows: RCTs of LBP and manipulation; randomized trials of other interventions for LBP; guidelines; systematic reviews and meta-analyses; basic science; diagnosticrelated articles; methodology; cognitive therapy and psychosocial issues; cohort and outcome studies; and others. Each group was subdivided by topic so that team members received approximately equal numbers of articles from each group, chosen randomly for distribution. On the basis of the CCGPP formation of an iterative process and the volume of work available, the team elected to limit consideration in this first iteration to guidelines, systematic reviews, meta-analyses, RCTs, and cohort studies.

 

Dr. Alex Jimenez’s Insight

How does chiropractic care benefit people with low back pain and sciatica?�As a chiropractor experienced in the management of a variety of spine health issues, including low back pain and sciatica, spinal adjustments and manual manipulations, as well as other non-invasive treatment methods, can be safely and effectively implemented towards the improvement of back pain symptoms. The purpose of the following research study is to demonstrate the evidence-based effects of chiropractic in the treatment of injuries and conditions of the musculoskeletal and nervous systems. The information in this article can educate patients on how alternative treatment options can help improve their low back pain and sciatica. As a chiropractor, patients may also be referred to other healthcare professionals, such as physical therapists, functional medicine practitioners and medical doctors, to help them further manage their low back pain and sciatica symptoms. Chiropractic care can be used to avoid surgical interventions for spine health issues.

 

Results and Discussion

 

A total of 887 source documents were initially obtained. This included a total of 12 guidelines, 64 RCTs, 20 systematic reviews/meta-analyses, and 12 cohort studies. Table 1 provides an overall summary of the number of studies evaluated.

 

Table 1 Number of Sources Rated by the Interdisciplinary Team of Reviewers and Used in Formulating Conclusions

 

Assurance and Advice

 

The search strategy used by the team was that developed by van Tulder et al, and the team identified 11 trials. Good evidence indicates that patients with acute LBP on bed rest have more pain and less functional recovery than those who stay active. There is no difference in pain and functional status between bed rest and exercises. For sciatica patients, fair evidence shows no real difference in pain and functional status between bed rest and staying active. There is fair evidence of no difference in pain intensity between bed rest and physiotherapy but small improvements in functional status. Finally, there is little difference in pain intensity or functional status between shorter-term or longer-term bed rest.

 

A Cochrane review by Hagen et al demonstrated small advantages in short-term and long-term for staying active over bed rest, as did a high-quality review by the Danish Society of Chiropractic and Clinical Biomechanics, including 4 systematic reviews, 4 additional RCTS, and 6 guidelines, on acute LBP and sciatica. The Cochrane review by Hilde et al included 4 trials and concluded a small beneficial effect for staying active for acute, uncomplicated LBP, but no benefit for sciatica. Eight studies on staying active and 10 on bed rest were included in an analysis by the group of Waddell. Several therapies were coupled with advice to stay active and include analgesic medication, physical therapy, back school, and behavioral counseling. Bed rest for acute LBP was similar to no treatment and placebo and less effective than alternative treatment. Outcomes considered across the studies were rate of recovery, pain, activity levels, and work time loss. Staying active was found to have a favorable effect.

 

Review of 4 studies not covered elsewhere assessed the use of brochures/booklets. The trend was for no differences in outcome for pamphlets. One exception was noted�that those who received manipulation had less bothersome symptoms at 4 weeks and significantly less disability at 3 months for those who received a booklet encouraging staying active.

 

In summary, assuring patients that they are likely to do well and advising them to stay active and avoid bed rest is a best practice for management of acute LBP. Bed rest for short intervals may be beneficial for patients with radiating leg pain who are intolerant of weight bearing.

 

Adjustment/Manipulation/Mobilization Vs Multiple Modalities

 

This review considered literature on high-velocity, lowamplitude (HVLA) procedures, often termed adjustment or manipulation, and mobilization. The HVLA procedures use thrusting maneuvers applied quickly; mobilization is applied cyclically. The HVLA procedure and mobilization may be mechanically assisted; mechanical impulse devices are considered HVLA, and flexion-distraction methods and continuous passive motion methods are within mobilization.

 

Image of a chiropractor performing spinal adjustments and manual manipulations for low back pain and sciatica.

 

The team recommends adopting the findings of the systematic review by Bronfort et al, with a quality score (QS) of 88, covering literature up to 2002. In 2006, the Cochrane collaboration reissued an earlier (2004) review of spinal manipulative therapy (SMT) for back pain performed by Assendelft et al. This reported on 39 studies up to 1999, several overlapping with those reported by Bronfort et al using different criteria and a novel analysis. They report no difference in outcome from treatment with manipulation vs alternatives. As several additional RCTs had appeared in the interim, the rationale for reissuing the older review without acknowledging new studies was unclear.

 

Acute LBP. There was fair evidence that HVLA has better short-term efficacy than mobilization or diathermy and limited evidence of better short-term efficacy than diathermy, exercise, and ergonomic modifications.

 

Chronic LBP. The HVLA procedure combined with strengthening exercise was as effective for pain relief as nonsteroidal antiinflammatory dugs with exercise. Fair evidence indicated that manipulation is better than physical therapy and home exercise for reducing disability. Fair evidence shows that manipulation improves outcomes more than general medical care or placebo in the short-term and to physical therapy in the long-term. The HVLA procedure had better outcomes than home exercise, transcutaneous�electrical nerve stimulation, traction, exercise, placebo and sham manipulation, or chemonucleolysis for disk herniation.

 

Mixed (Acute and Chronic) LBP. Hurwitz found that HVLA was the same as medical care for pain and disability; adding physical therapy to manipulation did not improve outcomes. Hsieh found no significant value for HVLA over back school or myofascial therapy. A short-term value of manipulation over a pamphlet and no difference between manipulation and McKenzie technique were reported by Cherkin et al. Meade contrasted manipulation and hospital care, finding greater benefit for manipulation over both short-term and long-term. Doran and Newell found that SMT resulted in greater improvement than physical therapy or corsets.

 

Acute LBP

 

Sick List Comparisons. Seferlis found that sick patients listed were significantly improved symptomatically after 1 month regardless of the intervention, including manipulation. Patients were more satisfied and felt that they were provided better explanations about their pain from practitioners who used manual therapy (QS, 62.5). Wand et al examined the effects of sick-listing oneself and noted that a group receiving assessment, advice, and treatment improved better than did a group getting assessment, advice, and who were put on a wait list for a 6-week period. Improvements were observed in disability, general health, quality of life, and mood, though pain and disability were not different at longterm follow-up (QS, 68.75).

 

Physiologic Therapeutic Modality and Exercise. Hurley and colleagues tested the effects of manipulation combined with interferential therapy compared to either modality alone. Their results showed all 3 groups improved function to the same degree, both at 6-month and at 12-month follow-up (QS, 81.25). Using a single-blinded experimental design to compare manipulation to massage and low-level electrostimulation, Godfrey et al found no differences between groups at the 2 to 3-week observation time frame (QS, 19). In the study by Rasmussen, results showed that 94% of the patients treated with manipulation were symptom-free within 14 days, compared to 25% in the group that received short-wave diathermy. Sample size was small, however, and as a result, the study was underpowered (QS, 18). The Danish systematic review examined 12 international sets of guidelines, 12 systematic reviews, and 10 randomized clinical trials on exercise. They found no specific exercises, regardless of type, that were useful for the treatment of acute LBP with the exception of McKenzie maneuvers.

 

Sham and Alternate Manual Method Comparisons. The study of Hadler balanced for effects of provider attention and physical contact with a first effort at a manipulation sham procedure. Patients in the group that entered the trial with greater prolonged illness at the outset were reported to have benefited from the manipulation. Similarly, they improved faster and to a greater degree (QS, 62.5). Hadler demonstrated that there was a benefit for a single session of manipulation compared to a session of mobilization (QS, 69). Erhard reported that the rate of positive response to manual treatment with a hand-heel rocking motion was greater than with extension exercises (QS, 25). Von Buerger examined the use of manipulation for acute LBP, comparing rotational manipulation to soft tissue massage. He found that the manipulation group responded better than the soft tissue group, although the effects occurred mainly in the short-term. The results were also hampered by the nature of the forced multiple choice selections on the data forms (QS, 31). Gemmell compared 2 forms of manipulation for LBP of less than 6 weeks of duration as follows: Meric adjusting (a form of HVLA) and Activator technique (a form of mechanically assisted HVLA). No difference was observed, and both helped to reduce pain intensity (QS, 37.5). MacDonald reported a short-term benefit in disability measures within the first 1 to 2 weeks of starting therapy for the manipulation group that disappeared by 4 weeks in a control group (QS, 38). The work of Hoehler, although containing mixed data for patients with acute and chronic LBP, is included here because a larger proportion of patients with acute LBP were involved in the study. Manipulation patients reported immediate relief more often, but there were no differences between groups at discharge (QS, 25).

 

Medication. Coyer showed that 50% of the manipulation group was symptom-free within 1 week and 87% were discharged symptom-free in 3 weeks, compared to 27% and 60%, respectively, of the control group (bed rest and analgesics) (QS, 37.5). Doran and Newell compared manipulation, physiotherapy, corset, or analgesic medication, using outcomes that examined pain and mobility. There were no differences between groups over time (QS, 25). Waterworth compared manipulation to conservative physiotherapy and 500 mg of diflunisal twice per day for 10 days. Manipulation showed no benefit for the rate of recovery (QS, 62.5). Blomberg compared manipulation to steroid injections and to a control group receiving conventional activating therapy. After 4 months, the manipulation group had less restricted motion in extension, less restriction in side-bending to both sides, less local pain on extension and right sidebending, less radiating pain, and less pain when performing a straight leg raise (QS, 56.25). Bronfort found no outcome differences between chiropractic care compared to medical care at 1 month of treatment, but there were noticeable improvements in the chiropractic group at both 3 and 6-month follow-up (QS, 31).

 

Subacute Back Pain

 

Staying Active. Grunnesjo compared combined effects of manual therapy with advice to stay active to advice alone in patients with acute and subacute LBP. The addition of�manual therapy appeared to reduce pain and disability more effectively than the �stay active� concept alone (QS, 68.75).

 

Physiologic Therapeutic Modality and Exercise. Pope demonstrated that manipulation offered better pain improvement than transcutaneous electrical nerve stimulation (QS 38). Sims-Williams compared manipulation to �physiotherapy.� Results demonstrated a short-term benefit for manipulation on pain and ability to do light work. Differences between groups waned at 3 and 12-month follow-ups (QS, 43.75, 35). Skargren et al compared chiropractic to physiotherapy for patients with LBP who had no treatment for the prior month. No differences in health improvements, costs, or recurrence rates were noted between the 2 groups. However, based on Oswestry scores, chiropractic performed better for patients who had pain for less than 1 week, whereas the physiotherapy seemed to be better for those who had pain for more than 4 weeks (QS, 50).

 

The Danish systematic review examined 12 international sets of guidelines, 12 systematic reviews, and 10 randomized clinical trials on exercise. Results suggested that exercise, in general, benefits patients with subacute back pain. Use of a basic program that can be readily modified to meet individual patient needs is recommended. Issues of strength, endurance, stabilization, and coordination without excessive loading can all be addressed without the use of high-tech equipment. Intensive training consisting of greater than 30 and less than 100 hours of training are most effective.

 

Sham and Alternate Manual Method Comparisons. Hoiriis compared efficacy of chiropractic manipulation to placebo/ sham for subacute LBP. All groups improved on measures of pain, disability, depression, and Global Impression of Severity. Chiropractic manipulation scored better than placebo in reducing pain and Global Impression of Severity scores (QS, 75). Andersson and colleagues compared osteopathic manipulation to standard care to patients with subacute LBP, finding that both groups improved for a 12-week period at about the same rate (QS, 50).

 

Medication Comparisons. In a separate treatment arm of the study of Hoiriis, the relative efficacy of chiropractic manipulation to muscle relaxants for subacute LBP was studied. In all groups, pain, disability, depression, and Global Impression of Severity decreased. Chiropractic manipulation was more effective than muscle relaxants in reducing Global Impression of Severity scores (QS, 75).

 

Chronic LBP

 

Staying Active Comparisons. Aure compared manual therapy to exercise in patients with chronic LBP who were sick listed. Although both groups showed improvements in pain intensity, functional disability, general health, and return to work, the manual therapy group showed significantly greater improvements than did the exercise group for all outcomes. Results were consistent for both the short-term and the longterm (QS, 81.25).

 

Physician Consult/Medical Care/Education. Niemisto compared combined manipulation, stabilization exercise, and physician consultation to consultation alone. The combined intervention was more effective in reducing pain intensity and disability (QS, 81.25). Koes compared general practitioner treatment to manipulation, physiotherapy, and a placebo (detuned ultrasound). Assessments were made at 3, 6, and 12 weeks. The manipulation group had a quicker and larger improvement in physical function compared to the other therapies. Changes in spinal mobility in the groups were small and inconsistent (QS, 68). In a follow-up report, Koes found during subgroup analysis that improvement in pain was greater for manipulation than for other treatments at 12 months when considering patients with chronic conditions, as well as those who were younger than 40 years (QS, 43). Another study by Koes showed that many patients in the nonmanipulation treatment arms had received additional care during follow-up. Yet, improvement in the main complaints and in physical functioning remained better in the manipulation group (QS, 50). Meade observed that chiropractic treatment was more effective than hospital outpatient care, as assessed using the Oswestry Scale (QS, 31). An RCT conducted in Egypt by Rupert compared chiropractic manipulation, after medical and chiropractic evaluation. Pain, forward flexion, active, and passive leg raise all improved to a greater degree in the chiropractic group; however, the description of alternate treatments and outcomes was ambiguous (QS, 50).

 

Triano compared manual therapy to educational programs for chronic LBP. There was greater improvement in pain, function, and activity tolerance in the manipulation group, which continued beyond the 2-week treatment period (QS, 31).

 

Physiologic Therapeutic Modality. A negative trial for manipulation was reported by Gibson (QS, 38). Detuned diathermy was reported to achieve better results over manipulation, although there were baseline differences between groups. Koes studied the effectiveness of manipulation, physiotherapy, treatment by a general practitioner, and a placebo of detuned ultrasound. Assessments were made at 3, 6, and 12 weeks. The manipulation group showed a quicker and better improvement in physical function capacity compared to the other therapies. Flexibility differences between groups were not significant (QS, 68). In a follow-up report, Koes found that a subgroup analysis demonstrated that improvement in pain was greater for those treated with manipulation, both for younger (b40) patients and those with chronic conditions at 12-month follow-up (QS, 43). Despite many patients in the nonmanipulation groups received additional care during follow-up, improvements remained better in the manipulation group than in the physical therapy group (QS, 50). In a separate report by the same group, there were improvements in both the physiotherapy and manual therapy groups with regard to severity of complaints and global perceived effect compared to general practitioner care;�however, the differences between the 2 groups was not significant (QS, 50). Mathews et al found that manipulation hastened recovery from LBP more than the control did.

 

Exercise Modality. Hemilla observed that SMT led to better long-term and short-term disability reduction compared to physical therapy or home exercise (QS, 63). A second article by the same group found that neither bone-setting nor exercise differed significantly from physical therapy for symptom control, though bone-setting was associated with improved lateral and forward-bending of the spine more than exercise (QS, 75). Coxhea reported that HVLA provided better outcomes when compared to exercise, corsets, traction, or no exercise when studied in the short-term (QS, 25). Conversely, Herzog found no differences between manipulation, exercise, and back education in reducing either pain or disability (QS, 6). Aure compared manual therapy to exercise in patients with chronic LBP who were also sick listed. Although both groups showed improvements in pain intensity, functional disability, and general health and returned to work, the manual therapy group showed significantly greater improvements than did the exercise group for all outcomes. This result persisted for both the short-term and the long-term (QS, 81.25). In the article by Niemisto and colleagues, the relative efficacy of combined manipulation, exercise (stabilizing forms), and physician consultation compared to consultation alone was investigated. The combined intervention was more effective in reducing pain intensity and disability (QS, 81.25). The United Kingdom Beam study found that manipulation followed by exercise achieved a moderate benefit at 3 months and a small benefit at 12 months. Likewise, manipulation achieved a small to moderate benefit at 3 months and a small benefit at 12 months. Exercise alone had a small benefit at 3 months but no benefit at 12 months. Lewis et al found improvement occurred when patients were treated by combined manipulation and spinal stabilization exercises vs use of a 10-station exercise class.

 

The Danish systematic review examined 12 international sets of guidelines, 12 systematic reviews, and 10 randomized clinical trials on exercise. Results suggested that exercise, in general, benefits patients with chronic LBP. No clear superior method is known. Use of a basic program that can be readily modified to meet individual patient needs is recommended. Issues of strength, endurance, stabilization, and coordination without excessive loading can all be addressed without the use of high-tech equipment. Intensive training consisting of greater than 30 and less than 100 hours of training are most effective. Patients with severe chronic LBP, including those off work, are treated more effectively with a multidisciplinary rehabilitation program. For post surgical rehabilitation, patients starting 4 to 6 weeks after disk surgery under intensive training receive greater benefit than with light exercise programs.

 

Sham and Alternate Manual Methods. Triano found that SMT produced significantly better results for pain and disability relief for the short-term, than did sham manipulation (QS, 31). Cote found no difference over time or for comparisons within or between the manipulation and mobilization groups (QS, 37.5). The authors posed that failure to observe differences may have been due to low responsiveness to change in the instruments used for algometry, coupled with a small sample size. Hsieh found no significant value for HVLA over back school or myofascial therapy (QS, 63). In the study by Licciardone, a comparison was made between osteopathic manipulation (which includes mobilization and soft tissue procedures as well as HVLA), sham manipulation, and a no-intervention control for patients with chronic LBP. All groups showed improvement. Sham and osteopathic manipulation were associated with greater improvements than seen in the no-manipulation group, but no difference was observed between the sham and manipulation groups (QS, 62.5). Both subjective and objective measures showed greater improvements in the manipulation group compared to a sham control, in a report by Waagen (QS, 44). In the work of Kinalski, manual therapy reduced the time of treatment of patients with LBP and concomitant intervertebral disk lesions. When disk lesions were not advanced, a decreased muscular hypertonia and increased mobility was noted. This article, however, was limited by a poor description of patients and methods (QS, 0).

 

Harrison et al reported a nonrandomized cohort controlled trial of treatment of chronic LBP consisting of 3-point bending traction designed to increase curvature of the lumbar spine. The experimental group received HVLA for pain control during the first 3 weeks (9 treatments). The control group received no treatment. Follow-up at a mean of 11 weeks showed no change in pain or curvature status for controls but a significant increase in curvature and reduction of pain in the experimental group. Average number of treatments to achieve this result was 36. Long-term followup at 17 months showed retention of benefits. No report of relationship between clinical changes and structural change was given.

 

Haas and colleagues examined the dose-response patterns of manipulation for chronic LBP. Patients were randomly allocated to groups receiving 1, 2, 3, or 4 visits per week for 3 weeks, with outcomes recorded for pain intensity and functional disability. A positive and clinically important effect of the number of chiropractic treatments on pain intensity and disability at 4 weeks was associated with the groups receiving the higher rates of care (QS, 62.5). Descarreaux et al extended this work, treating 2 small groups for 4 weeks (3 times per week) after 2 baseline evaluations separated by 4 weeks. One group was then treated every 3 weeks; the other did not. Although both groups had lower Oswestry scores at 12 weeks, at 10 months, the improvement only persisted for the extended SMT group.

 

Medication. Burton and colleagues demonstrated that HVLA led to greater short-term improvements in pain and disability than did chemonucleolysis for managing disk�herniation (QS, 38). Bronfort studied SMT combined with exercise vs a combination of nonsteroidal antiinflammatory drugs and exercise. Similar results were obtained for both groups (QS, 81). Forceful manipulation coupled with sclerosant therapy (injection of a proliferant solution composed of dextrose-glycerine-phenol) was compared to lower force manipulation combined with saline injections, in a study by Ongley. The group receiving forceful manipulation with sclerosant fared better than the alternate group, but effects cannot be separated between the manual procedure and the sclerosant (QS, 87.5). Giles and Muller compared HVLA procedures to medication and acupuncture. Manipulation showed greater improvement in frequency of back pain, pain scores, Oswestry, and SF-36 compared to the other 2 interventions. Improvements lasted for 1 year. Weaknesses of the study were use of a compliers-only analysis as intention to treat for the Oswestry, and Visual Analogue Scale (VAS) was not significant.

 

Sciatica/Radicular/Radiating Leg Pain

 

Staying Active/Bed Rest. Postacchini studied a mixed group of patients with LBP, with and without radiating leg pain. Patients could be classified as acute or chronic and were evaluated at 3 weeks, 2 months, and 6 months postonset. Treatments included manipulation, drug therapy, physiotherapy, placebo, and bed rest. Acute back pain without radiation and chronic back pain responded well to manipulation; however, in none of the other groups did manipulation fare as well as other interventions (QS, 6).

 

Physician Consult/Medical Care/Education. Arkuszewski looked at patients with lumbosacral pain or sciatica. One group received drugs, physiotherapy, and manual examination, whereas the second added manipulation. The group receiving manipulation had a shorter treatment time and a more marked improvement. At 6-month follow-up, the manipulation group showed better neuromotor system function and a better ability to continue employment. Disability was lower in the manipulation group (QS, 18.75).

 

Physiologic Therapeutic Modality. Physiotherapy combined with manual manipulation and medication was examined by Arkuszewski, in contrast to the same scheme with manipulation added, as noted above. Outcomes from manipulation were better for neurologic and motor function as well as disability (QS, 18.75). Postacchini looked at patients with acute or chronic symptoms evaluated at 3 weeks, 2 months, and 6 months postonset. Manipulation was not as effective for managing the patients with radiating leg pain as the other treatment arms (QS, 6). Mathews and colleagues examined multiple treatments including manipulation, traction, sclerosant use, and epidural injections for back pain with sciatica. For patients with LBP and restricted straight leg raise test, manipulation conferred highly significant relief, more so than alternate interventions (QS, 19). Coxhead et al included among their subjects patients who had radiating pain at least to the buttocks. Interventions included traction, manipulation, exercise, and corset, using a factorial design. After 4 weeks of care, manipulation showed a significant degree of benefit on one of the scales used to assess progress. There were no real differences between groups at 4 months and 16 months posttherapy, however (QS, 25).

 

Exercise Modality. In the case of LBP after laminectomy, Timm reported that exercises conferred benefit both for pain relief and cost-effectiveness (QS, 25). Manipulation had only a small influence on improvement of either symptoms or function (QS, 25). In the study by Coxhead et al, radiating pain to at least the buttocks was better after 4 weeks of care for manipulation, in contrast to other treatments that disappeared 4 months and 16 months posttherapy (QS, 25).

 

Sham and Alternate Manual Method. Siehl looked at the use of manipulation under general anesthesia for patients with LBP and unilateral or bilateral radiating leg pain. Only temporary clinical improvement was noted when traditional electromyographic evidence of nerve root involvement was present. With negative electromyography, manipulation was reported to provide lasting improvement (QS, 31.25) Santilli and colleagues compared HVLA to soft tissue pressing without any sudden thrust in patients with moderate acute back and leg pain. The HVLA procedures were significantly more effective in reducing pain, reaching a pain-free status, and the total number of days with pain. Clinically significant differences were noted. The total number of treatment sessions was capped at 20 on a dosage of 5 times per week with care depending on pain relief. Follow-up showed relief persisting through 6 months.

 

Medication. Mixed acute and chronic back pain with radiation treated in a study using multiple treatment arms were evaluated at 3 weeks, 2 months, and 6 months postonset by the group of Postacchini. Medication management fared better than did manipulation when radiating leg pain was present (QS, 6). Conversely, for the work of Mathews and colleagues, the group of patients with LBP and limited straight leg raise test responded more to manipulation than to epidural steroid or sclerosants (QS, 19).

 

Disk Herniation

 

Nwuga studied 51 subjects who were having a diagnosis of prolapsed intervertebral disk and who had been referred for physical therapy. Manipulation was reported to be superior to conventional therapy (QS, 12.5). Zylbergold found that there were no statistical differences between 3 treatments�lumbar flexion exercises, home care, and manipulation. Short-term follow-up and a small sample size were posed by the author as a basis for failing to reject the null hypothesis (QS, 38).

 

Exercise

 

Exercise is one of the most well-studied forms of treatment of low back disorders. There are many different approaches to�exercise. For this report, it is important only to differentiate multidisciplinary rehabilitation. These programs are designed for patients with especially chronic condition with significant psychosocial problems. They involve trunk exercise, functional task training including work simulation/vocational training, and psychological counseling.

 

Image of a healthcare professional helping a patient perform exercises for low back pain and sciatica.

 

In a recent Cochrane review on exercise for the treatment of nonspecific LBP (QS, 82), effectiveness of exercise therapy in patients classified as acute, subacute, and chronic was compared to no treatment and alternate treatments. Outcomes included the assessment of pain, function, return to work, absenteeism, and/or global improvements. In the review, 61 trials met the inclusion criteria, most of which dealt with chronic (n = 43), whereas smaller numbers addressed acute (n = 11) and subacute (n = 6) pain. The general conclusions were as follows:

 

  • exercise is not effective as a treatment of acute LBP,
  • evidence that exercise was effective in chronic populations relative to comparisons made at follow-up periods,
  • mean improvements of 13.3 points for pain and 6.9 points for function were observed, and
  • there is some evidence that graded-activity exercise is effective for subacute LBP but only in the occupational setting

 

The review examined population and intervention characteristics, as well as outcomes to reach its conclusions. Extracting data on return to work, absenteeism, and global improvement proved so difficult that only pain and function could be quantitatively described.

 

Eight studies scored positively on key validity criteria. With regard to clinical relevance, many of the trials presented inadequate information, with 90% reporting the study population but only 54% adequately describing the exercise intervention. Relevant outcomes were reported in 70% of the trials.

 

Exercise for Acute LBP. Of the 11 trials (total n = 1192), 10 had nonexercise comparison groups. The trials presented conflicting evidence. Eight low-quality trials showed no differences between exercise and usual care or no treatment. Pooled data showed that there was no difference in shortterm pain relief between exercise and no treatment, no difference in early follow-up for pain when compared to other interventions, and no positive effect of exercise on functional outcomes.

 

Subacute LBP. In 6 studies (total n = 881), 7 exercise groups had a nonexercise comparison group. The trials offered mixed results with regard to evidence of effectiveness, with fair evidence of effectiveness for a graded-exercise activity program as the only notable finding. Pooled data did not show evidence to either support or refute the use of exercise for subacute LBP, either for decreasing pain or improving function.

 

Chronic LBP. There were 43 trials included in this group (total n = 3907). Thirty-three of the studies had nonexercise comparison groups. Exercise was at least as effective as other conservative interventions for LBP, and 2 high-quality studies and 9 lower-quality studies found exercise to be more effective. These studies used individualized exercise programs, focusing mainly on strengthening or trunk stabilization. There were 14 trials that found no difference between exercise and other conservative interventions; of these, 2 were rated highly and 12 rated lower. Pooling the data showed a mean improvement of 10.2 (95% confidence interval [CI], 1.31-19.09) points on a 100-mm pain scale for exercise compared to no treatment and 5.93 (95% CI, 2.21- 9.65) points compared to other conservative treatments. Functional outcomes also showed improvements as follows: 3.0 points at earliest follow-up compared to no treatment (95% CI, ?0.53 to 6.48) and 2.37 points (95% CI, 1.04-3.94) compared to other conservative treatments.

 

Indirect subgroup analysis found that trials examining health care study populations had higher mean improvements in pain and physical functioning compared to their comparison groups or to trials set in occupational or general populations.

 

The review authors offered the following conclusions:

 

  1. In acute LBP, exercises are not more effective than other conservative interventions. Meta-analysis showed no advantage over no treatment of pain and functional outcomes over the short or long-term.
  2. There is fair evidence of effectiveness of a gradedactivity exercise program in subacute LBP in occupational settings. The effectiveness for other types of exercise therapy in other populations is unclear.
  3. In chronic LBP, there is good evidence that exercise is at least as effective as other conservative treatments. Individually designed strengthening or stabilizing programs appear to be effective in health care settings. Meta-analysis found functional outcomes significantly improved; however, the effects were very small, with a less than 3-point (of 100) difference between the exercise and comparison groups at earliest follow-up. Pain outcomes were also significantly improved in groups receiving exercises relative to other comparisons, with a mean of approximately 7 points. Effects were similar over longer follow-up, though confidence intervals increased. Mean improvements in pain and functioning may be clinically meaningful in studies from health care populations in which improvements were significantly greater than those observed in studies from general or mixed populations.

 

The Danish group review of exercise was able to identify 5 systematic reviews and 12 guidelines that discussed exercise for acute LBP, 1 systematic review and 12 guidelines for subacute, and 7 systematic reviews and 11 guidelines for chronic. Furthermore, they identified 1 systematic review that selectively evaluated for postsurgical�cases. Conclusions were essentially the same as the Cochrane review, with the exceptions that there was limited support for McKenzie maneuvers for patients with acute condition and for intensive rehabilitation programs for 4 to 6 weeks after disk surgery over light exercise programs.

 

Natural and Treatment History for LBP

 

Most studies have demonstrated that nearly half of LBP will improve within 1 week, whereas nearly 90% of it will be gone by 12 weeks. Even more, Dixon demonstrated that perhaps as much as 90% of LBP will resolve on its own, without any intervention whatsoever. Von Korff demonstrated that a significant number of patients with acute LBP will have persistent pain if they are observed up to 2 years.

 

Phillips found that nearly 4 of 10 people will have LBP after an episode at 6 months from onset, even if the original pain has disappeared because more than 6 in 10 will have at least 1 relapse during the first year after an episode. These initial relapses occur within 8 weeks most commonly and may reoccur over time, though in decreasing percentages.

 

Workers’ compensation injury patients were observed for 1 year to examine symptom severity and work status. Half of those studied lost no work time in the first month after injury, but 30% did lose time from work due to their injury over the course of 1 year. Of those who missed work in the first month due to their injury and had already been able to return to work, nearly 20% had absence later in that same year. This implies that assessing return to work at 1 month after injury will fail to give an honest depiction of the chronic, episodic nature of LBP. Although many patients have returned to work, they will later experience continuing problems and work-related absences. Impairment present at more than 12 weeks postinjury may be far higher than what has been previously reported in the literature, where rates of 10% are common. In fact, the rates may go up to 3 to 4 times higher.

 

In a study by Schiotzz-Christensen and colleagues, the following was noted. In relation to sick leave, LBP has a favorable prognosis, with a 50% return to work within the first 8 days and only 2% on sick leave after 1 year. However, 15% had been on sick leave during the following year and about half continued to complain of discomfort. This suggested that an acute episode of LBP significant enough to cause the patient to seek a visit to a general practitioner is followed by a longer period of low-grade disability than previously reported. Also, even for those who returned to work, up to 16% indicated that they were not functionally improved. In another study looking at outcomes after 4 weeks after initial diagnosis and treatment, only 28% of patients did not experience any pain. More strikingly, the persistence of pain differed between groups that had radiating pain and those that did not, with 65% of the former feeling improvement at 4 weeks, vs 82% of the latter. The general findings from this study differ from others in that 72% of patients still experienced pain 4 weeks after initial diagnosis.

 

Hestbaek and colleagues reviewed a number of articles in a systematic review. The results showed that the reported proportion of patients who still experienced pain after 12 months after onset was 62% on average, with 16% sick-listed 6 months after onset, and with 60% experiencing relapse of work absence. Also, they found that the mean reported prevalence of LBP in patients who had past episodes of LBP was 56%, compared to just 22% for those who had no such history. Croft and colleagues performed a prospective study looking at the outcomes of LBP in general practice, finding that 90% of patients with LBP in primary care had stopped consulting with symptoms within 3 months; however, most were still experiencing LBP and disability 1 year after the initial visit. Only 25% had fully recovered within that same year.

 

There are even different results in the study by Wahlgren et al. Here, most patients continued to experience pain at both 6 and 12 months (78% and 72%, respectively). Only 20% of the sample had fully recovered by 6 months and only 22% by 12 months.

 

Von Korff has provided a lengthy list of data he considers relevant to assessing the clinical course of back pain as follows: age, sex, race/ethnicity, years of education, occupation, change in occupation, employment status, disability insurance status, litigation status, recency/age at first onset of back pain, recency/age when care was sought, recency of back pain episode, duration of current/most recent episode of back pain, number of back pain days, current pain intensity, average pain intensity, worst pain intensity, ratings of interference with activities, activity limitation days, clinical diagnosis for this episode, bed rest days, work loss days, recency of back pain flare-up, and duration of the most recent flare-up.

 

In a practice-based observational study by Haas et al of almost 3000 patients with acute and chronic condition treated by chiropractors and primary care medical doctors, pain was noted in patients with acute and chronic condition up to 48 months after enrollment. At 36 months, 45% to 75% of patients reported at least 30 days of pain in the prior year, and 19% to 27% of patients with chronic condition recalled daily pain over the previous year.

 

The variability noted in these and many other studies can be explained in part by the difficulty in making an adequate diagnosis, by the different classification schemes used in classifying LBP, by the different outcome tools used in each study and by many other factors. It also points up the extreme difficulty in getting a handle on the day-to-day reality for those who have LBP.

 

Common Markers and Rating Complexity for LBP

 

What Are the Relevant Benchmarks for Evaluating Process of Care?. One benchmark is described above, that being natural history. Complexity and risk stratification are important, as�are cost issues; however, cost-effectiveness is beyond the scope of this report.

 

It is understood that patients with uncomplicated LBP improve faster than those with various complications, the most notable of which is radiating pain. Many factors may influence the course of back pain, including comorbidity, ergonomic factors, age, the level of fitness of the patient, environmental factors, and psychosocial factors. The latter is receiving a great deal of attention in the literature, though as noted elsewhere in this book, such consideration may not be justified. Any of these factors, alone or in combination, may hamper or retard the recovery period after injury.

 

It seems that biomechanical factors play an important role in the incidence of first-time episodes of LBP and its attendant problems such as work loss; psychosocial factors come into play more in subsequent episodes of LBP. The biomechanical factors can lead to tissue tearing, which then create pain and limited ability for years to follow. This tissue damage cannot be seen on standard imaging and may only be apparent upon dissection or surgery.

 

Risk factors for LBP include the following:

 

  • age, sex, severity of symptoms;
  • increased spinal flexibility, decreased muscle endurance;
  • prior recent injury or surgery;
  • abnormal joint motion or decreased body mechanics;
  • prolonged static posture or poor motor control;
  • work-related such as vehicle operation, sustained loads, materials handling;
  • employment history and satisfaction; and
  • wage status.

 

IJzelenberg and Burdorf investigated whether demographic, work-related physical, or psychosocial risk factors involved in the occurrence of musculoskeletal conditions determine subsequent health care use and sick leave. They found that within 6 months, nearly one third of industrial workers with LBP (or neck and upper extremity problems) had a recurrence of sick leave for that same problem and a 40% recurrence of health care use. Work-related factors associated with musculoskeletal symptoms were similar to those associated with health care use and sick leave; but, for LBP, older age and living alone strongly determined whether patients with these problems took any sick leave. The 12- month prevalence of LBP was 52%, and of those with symptoms at baseline, 68% had a recurrence of the LBP. Jarvik and colleagues add depression as an important predictor of new LBP. They found the use of MRI to be a less important predictor of LBP than depression.

 

What Are the Relevant Outcome Measures?. The Clinical Practice Guidelines formulated by the Canadian Chiropractic Association and the Canadian Federation of Chiropractic Regulatory Boards note that there are a number of outcomes that may be used to demonstrate change as a result of treatment. These should be both reliable and valid. According to the Canadian guidelines, appropriate standards are useful in chiropractic practice because they are able to perform the following:

 

  • consistently evaluate the effects of care over time;
  • help indicate the point of maximum therapeutic improvement;
  • uncover problems related to care such as noncompliance;
  • document improvement to the patient, doctor, and third parties;
  • suggest modifications of the goals of treatment if necessary;
  • quantify the clinical experience of the doctor;
  • justify the type, dose, and duration of care;
  • help provide a database for research; and
  • assist in establishing standards of treatment of specific conditions.

 

The broad general classes of outcomes include functional outcomes, patient perception outcomes, physiologic outcomes, general health assessments, and subluxation syndrome outcomes. This chapter addresses only functional and patient perception outcomes assessed by questionnaires and functional outcomes assessed by manual procedures.

 

Functional Outcomes. These are outcomes that measure the patient’s limitations in going about his or her normal daily activities. What is being looked at is the effect of a condition or disorder on the patient (ie, LBP, for which a specific diagnosis may not be present or possible) and its outcome of care. Many such outcome tools exist. Some of the better known include the following:

 

  • Roland Morris Disability Questionnaire,
  • Oswestry Disability Questionnaire,
  • Pain Disability Index,
  • Neck Disability Index,
  • Waddell Disability Index, and
  • Million Disability Questionnaire.

 

These are only some of the existing tools for assessing function.

 

In the existing RCT literature for LBP, functional outcomes have been shown to be the outcome that demonstrates the greatest change and improvement with SMT. Activities of daily living, along with patient selfreporting of pain, were the 2 most notable outcomes to show such improvement. Other outcomes fared less well, including trunk range of motion (ROM) and straight leg raise.

 

In the chiropractic literature, the outcome inventories used most frequently for LBP are the Roland Morris Disability Questionnaire and the Oswestry Questionnaire. In a study in 1992, Hsieh found that both tools provided consistent results over the course of his trial, although the results from the 2 questionnaires differed.

 

Patient Perception Outcomes. Another important set of outcomes involve patient perception of pain and their satisfaction with care. The first involves measuring changes in pain perception over time of its intensity, duration, and frequency. There are a number of valid tools available that can accomplish this, including the following:

 

Visual analog scale�this is a 10-cm line that has pain descriptions noted at both ends of that line representing no pain to intolerable pain; the patient is asked to mark a point on that line that reflects their perceived pain intensity. There are a number of variants for this outcome, including the Numerical Rating Scale (where the patient provides a number between 0 and 10 to represent the amount of pain they have) and the use of pain levels from 0 to 10 depicted pictorially in boxes, which the patient may check. All of these appear to be equally reliable, but for ease of use, either the standard VAS or Numerical Rating Scale is commonly used.

 

Pain diary�these may be used to help monitor a variety of different pain variables (for example, frequency, which the VAS cannot measure). Different forms may be used to collect this information, but it is typically completed on a daily basis.

 

McGill Pain Questionnaire�this scale helps quantify several psychologic components of pain as follows: cognitive-evaluative, motivational-affective, and sensory discriminative. In this instrument, there are 20 categories of words that describe the quality of pain. From the results, 6 different pain variables can be determined.

 

All of the above instruments have been used at various times to monitor the progress of treatment of back pain with SMT.

 

Patient satisfaction addresses both the effectiveness of care as well as the method of receiving that care. There are numerous methods of assessing patient satisfaction, and not all of them were designed to be specifically used for LBP or for manipulation. However, Deyo did develop one for use with LBP. His instrument examines the effectiveness of care, information, and caring. There is also the Patient Satisfaction Questionnaire, which assesses 8 separate indices (such as efficacy/outcomes or professional skill, for example). Cherkin noted that the Visit Specific Satisfaction Questionnaire can be used for chiropractic outcome assessment.

 

Recent work has shown that patient confidence and satisfaction with care are related to outcomes. Seferlis found that patients were more satisfied and felt that they were provided better explanations about their pain from practitioners who used manual therapy. Regardless of treatment, highly satisfied patients at 4 weeks were more likely than less satisfied patients to perceive greater pain improvement throughout 18-month follow-up in a study by Hurwitz et al. Goldstein and Morgenstern found a weak association between treatment confidence in the therapy they received and greater improvement in LBP. A frequent assertion is that benefits observed from application of manipulation methods are a result of physician attention and touching. Studies directly testing this hypothesis were conducted by Hadler et al in patients with acute condition and by Triano et al in patients with subacute and chronic condition. Both studies compared manipulation to a placebo control. In the study of Hadler, the control balanced for provider time attention and frequency, whereas Triano et al also added an education program with home exercise recommendations. In both cases, results demonstrated that although attention given to patients was associated with improvement over time, patients receiving manipulation procedures improved more quickly.

 

General Health Outcome Measures. This has traditionally been a difficult outcome to effectively measure but a number of more recent instruments are demonstrating that it can be done reliably. The 2 major instruments for doing so are the Sickness Impact Profile and the SF-36. The first assesses dimensions such as mobility, ambulation, rest, work, social interaction, and so on; the second looks primarily at well being, functional status, and overall health, as well as 8 other health concepts, to ultimately determine 8 indices that can be used to determine overall health status. Items here include physical functioning, social functioning, mental health, and others. This tool has been used in many settings and has also been adapted into shorter forms as well.

 

Physiologic Outcome Measures. The chiropractic profession has a number of physiologic outcomes that are used with regard to the patient care decision-making process. These include such procedures as ROM testing, muscle function testing, palpation, radiography, and other less common procedures (leg length analysis, thermography, and others). This chapter addresses only the physiologic outcomes assessed manually.

 

Range of Motion. This examination procedure is used by nearly every chiropractor and is used to assess impairment because it is related to spinal function. It is possible to use ROM as a means to monitor improvement in function over time and, therefore, improvement as it relates to the use of SMT. One can assess regional and global lumbar motion, for example, and use that as one marker for improvement.

 

Range of motion can be measured via a number of different means. One can use standard goniometers, inclinometers, and more sophisticated tools that require the use of specialized equipment and computers. When doing so, it is important to consider the reliability of each individual method. A number of studies have assessed various devices as follows:

 

  • Zachman found the use of the rangiometer moderately reliable,
  • Nansel found that using 5 repeated measures of cervical spine motion with an inclinometer to be reliable,
  • Liebenson found that the modified Schrober technique, along with inclinometers and flexible spinal rulers had the best support from the literature,
  • Triano and Schultz found that ROM for the trunk, along with trunk strength ratios and myoelectrical activity, was good indicator for LBP disability, and
  • a number of studies found that the kinematic measurement of ROM for spinal mobility is reliable.

 

Muscle Function. Evaluating muscle function may be done using an automated system or by manual means. Although manual muscle testing has been a common diagnostic practice within the chiropractic profession, there are few studies demonstrating clinical reliability for the procedure, and these are not considered to be of high quality.

 

Automated systems are more reliable and are capable of assessing muscle parameters such as strength, power, endurance, and work, as well as assess different modes of muscle contraction (isotonic, isometric, isokinetic). Hsieh found that a patient-initiated method worked well for specific muscles, and other studies have shown the dynamometer to have good reliability.

 

Leg Length Inequality. Very few studies of leg length have shown acceptable levels of reliability. The best methods for assessing reliability and validity of leg length involve radiographic means and are therefore subject to exposure to ionizing radiation. Finally, the procedure has not been studied as to validity, making the use of this as an outcome questionable.

 

Soft Tissue Compliance. Compliance is assessed by both manual and mechanical means, using the hand alone or using a device such as an algometer. By assessing compliance, the chiropractor is looking to assess muscle tone.

 

Early tests of compliance by Lawson demonstrated good reliability. Fisher found increases in tissue compliance with subjects involved in physical therapy. Waldorf found that prone segmental tissue compliance had good test/retest variation of less than 10%.

 

Pain tolerance assessed using these means has been found reliable, and Vernon found it was a useful measure in assessing the cervical paraspinal musculature after adjusting. The guidelines group from the Canadian Chiropractic Association and the Canadian Federation of Chiropractic Regulatory Boards concluded that �the assessments are safe and inexpensive and appear to be responsive to conditions and treatments commonly seen in chiropractic practice.�

 

Group Portrait Of Workers In Medical Professions

 

Conclusion

 

Existing research evidence regarding the usefulness of spinal adjusting/manipulation/mobilization indicates the following:

 

  1. As much or more evidence exists for the use of SMT to reduce symptoms and improve function in patients with chronic LBP as for use in acute and subacute LBP.
  2. Use of exercise in conjunction with manipulation is likely to speed and improve outcomes as well as minimize episodic recurrence.
  3. There was less evidence for the use of manipulation for patients with LBP and radiating leg pain, sciatica, or radiculopathy.
  4. Cases with high severity of symptoms may benefit by referral for comanagement of symptomswith medication.
  5. There was little evidence for the use of manipulation for other conditions affecting the low back and very few articles to support a higher rating.

 

Exercise and reassurance have been shown to be of value primarily in chronic LBP and low back problems associated with radicular symptoms. A number of standardized, validated tools are available to help capture meaningful clinical improvement over the course of low back care. Typically, functional improvement (as opposed to simple reported reduction in pain levels) may be clinically meaningful for monitoring responses to care. The literature reviewed remains relatively limited in predicting responses to care, tailoring specific combinations of intervention regimens (although the combination of manipulation and exercise may be better than exercise alone), or formulating condition-specific recommendations for frequency and�duration of interventions. Table 2 summarizes the recommendations of the team, based on the review of the evidence.

 

Table 2 Summary of Conclusions

 

Practical Applications

 

  • Evidence exists for the use of spinal manipulation to reduce symptoms and improve function in patients with chronic, acute, and subacute LBP.
  • Exercise in conjunction with manipulation is likely to speed and improve outcomes and minimize recurrence

 

In conclusion,�more evidence-based research studies have become available regarding the effectiveness of chiropractic care for low back pain and sciatica. The article also demonstrated that exercise should be used together with chiropractic to help speed up the rehabilitation process and further improve recovery. In most cases, chiropractic care can be used for the management of low back pain and sciatica, without the need for surgical interventions. However, if surgery is required to achieve recovery, a chiropractor may refer the patient to the next best healthcare professional. Information referenced from the National Center for Biotechnology Information (NCBI). The scope of our information is limited to chiropractic as well as to spinal injuries and conditions. To discuss the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .

 

Curated by Dr. Alex Jimenez

 

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Additional Topics: Sciatica

 

Sciatica is referred to as a collection of symptoms rather than a single type of injury or condition. The symptoms are characterized as radiating pain, numbness and tingling sensations from the sciatic nerve in the lower back, down the buttocks and thighs and through one or both legs and into the feet. Sciatica is commonly the result of irritation, inflammation or compression of the largest nerve in the human body, generally due to a herniated disc or bone spur.

 

blog picture of cartoon paperboy big news

 

IMPORTANT TOPIC: EXTRA EXTRA: Treating Sciatica Pain

 

 

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Cause Of Sciatica: Six Sources

Cause Of Sciatica: Six Sources

Cause Of Sciatica: Several lumbar spine (lower back) disorders can cause sciatica. Sciatica is often described as mild to intense pain in the left or right leg. Sciatica is caused by compression of one or more of the 5 sets of nerve roots in the lower back. Sometimes doctors call sciatica a radiculopathy. Radiculopathy is a medical term used to describe pain, numbness, tingling, and weakness in the arms or legs caused by a nerve root problem. If the nerve problem is in the neck, it is called a cervical radiculopathy. However, since sciatica affects the low back, it is called a lumbar radiculopathy.

Pathways To Sciatic Nerve Pain

Five sets of paired nerve roots in the lumbar spine combine to create the sciatic nerve. Starting at the back of the pelvis (sacrum), the sciatic nerve runs from the back, under the buttock, and downward through the hip area into each leg. Nerve roots are not “solitary” structures but are part of the body’s entire nervous system capable of transmitting pain and sensation to other parts of the body. Radiculopathy occurs when compression of a nerve root from a disc rupture (herniated disc) or bone spur (osteophyte) occurs in the lumbar spine prior to it joining the sciatic nerve.

sciatica causeWhat Causes Sciatic Nerve Compression?

Several spinal disorders can cause spinal nerve compression and sciatica or lumbar radiculopathy. The 6 most common are:

  • a bulging or herniated disc
  • lumbar spinal stenosis
  • spondylolisthesis
  • trauma
  • piriformis syndrome
  • spinal tumors

Sciatica�Cause:�6 Leading Sources

Several lumbar spine (lower back) disorders can cause sciatica. Sciatica is often described as mild to intense pain in the left or right leg. Sciatica is caused by compression of one or more of the 5 sets of nerve roots in the lower back. Sometimes doctors call sciatica a radiculopathy. Radiculopathy is a medical term used to describe pain, numbness, tingling, and weakness in the arms or legs caused by a nerve root problem. If the nerve problem is in the neck, it is called a cervical radiculopathy. However, since sciatica affects the low back, it is called a lumbar radiculopathy.

Sciatica Cause #1: Lumbar Bulging Disc Or Herniated Disc

sciatica cause

A bulging disc is also known as a contained disc disorder. This means the gel-like center (nucleus pulposus) remains “contained” within the tire-like outer wall (annulus fibrosus) of the disc.

A herniated disc occurs when the nucleus breaks through the annulus fibrosus. It is called a “non-contained” disc disorder. Whether a disc bulges or herniates, disc material can press against an adjacent nerve root and compress delicate nerve tissue and cause sciatica.

The consequences of a herniated disc are worse. Not only does the herniated disc cause direct compression of the nerve root against the interior of the bony spinal canal, but the disc material itself also contains an acidic, chemical irritant (hyaluronic acid) that causes nerve inflammation. In both cases, nerve compression and irritation cause inflammation and pain, often leading to extremity numbness, tingling, and muscle weakness.

Herniated disc is a relatively common condition that can occur anywhere along the spine, but most often affects the lower back or neck region. Also known as a slipped disc or ruptured disc, a herniated disc develops when one of the cushion-like pads between the vertebrae moves out of position and presses on adjacent nerves.

Herniated discs are typically caused by overuse injuries or trauma to the spine; however, disc conditions can also develop as a result of the normal aging process. It is also known that there is a genetic factor that contributes to the development of disc degeneration and herniated disc. In most cases, a herniated disc in the lower back will heal within six months, as the size of herniation shrinks with time via resorption. Surgery may be needed if medication, physical therapy and other treatments fail.

What Is A Disc?

Spinal discs are cushion-like pads located between the vertebrae. Without these �shock absorbers,� the bones in the spine would grind against one another. In addition to giving the spine flexibility and making movements such as twisting and bending possible, discs protect the spine by absorbing the impact of trauma and body weight. Each disc has a strong outer layer called annulus fibrosus and a soft, gel-like center, called nucleus pulposus. There are fibers on the outside of each disc that attach to adjacent vertebrae and hold the disc in place. A herniated disc occurs when the outer layer tears or ruptures and the gel-like center leaks into the spinal canal.

The spinal canal has just enough space to house the spinal cord and spinal fluid. When a disc herniates and spills into the spinal canal, it can cause compression of the nerves or spinal cord. Intense, debilitating pain and alterations in sensation often occur. In addition, the gel-like substance inside the disc releases chemical irritants that contribute to nerve inflammation and pain.

What Causes A Herniated Disc?

As we age, the spinal discs gradually lose fluid volume. This process starts at about age 30 and progresses slowly, over time. As the discs dry out, microscopic cracks or tears can form on the outer surface, causing it to become brittle, weak and more susceptible to injury. The most common causes of herniated disc are:

  • Wear and tear: Discs dry out and aren�t as flexible as they once were.
  • Repetitive movements: Work, lifestyle, and certain sports activities that put stress on the spine, especially the lower back, further weaken an already vulnerable area.
  • Lifting the wrong way: Never lift while bent at the waist. Proper lifting entails lifting with your legs and a straight back.
  • Injury: High-impact trauma can cause the disc to bulge, tear or rupture.
  • Obesity: Carrying excess weight puts an undue amount of strain on the spine.
  • Genetics: There are some genes that are more commonly present in individuals with disc degeneration. More research is needed to investigate the role of these genes�they could be targets of biological treatment in the future.

What Are The Symptoms Of A Herniated Disc?

Pain from a herniated disc can vary, depending on the location and severity of the injury. It is typically felt on one side of the body.

If the injury is minimal, little or no pain may be felt. If the disc ruptures, pain can be severe and unrelenting. Pain may radiate to an extremity in a specific nerve root distribution if significant nerve impingement has occurred. For example, sciatica is frequently caused by a herniated disc in the lower back. Herniated disc can manifest itself with a range of symptoms, including:

  • Dull ache to severe pain
  • Numbness, tingling, burning
  • Muscle weakness; spasm; altered reflexes
  • Loss of bowel or bladder control (Note: These symptoms constitute a medical emergency. If they occur, seek medical attention immediately).

How Is A Herniated Disc Diagnosed?

History and physical examination point to a diagnosis of herniated disc. A herniated disc is likely if low back pain is accompanied by radiating leg pain in a nerve root distribution with positive straight leg raising test (ie, elevating the leg while lying down causes radiating pain down the leg), and other neurologic deficits such as numbness, weakness, and altered reflexes.

Imaging studies are usually ordered to confirm a diagnosis of herniated disc. X-rays are not the imaging medium of choice because soft tissues (eg, discs, nerves) are hard to capture with this technology. However, they may be used as an initial tool to rule out other disorders such as a growth or fracture. Confirmation of the suspicion of herniated disc is generally accomplished with:

  • Magnetic Resonance Imaging (MRI): This technology reveals the spinal cord, surrounding soft tissue and nerves. It is the best imaging study to support the diagnosis of a herniated disc.
  • Nerve Conduction Studies (NCS) and Electromyogram (EMG): These studies use electrical impulses to measure the degree of damage to the nerve/s caused by compression from a herniated disc and other conditions that cause nerve impingement can be ruled out. NCS and EMG are not routine tests to diagnose herniated disc.

Herniated discs sometimes heal on their own through a process called resorption. This means that the disc fragments are absorbed by the body. Most people suffering from herniated disc respond well to conservative treatment and do not require surgery.

Sciatica Cause #2: Lumbar Spinal Stenosis

sciatica causeSpinal stenosis is a nerve compression disorder most often affecting older adults. Leg pain similar to sciatica may occur as a result of lumbar spinal stenosis. The pain is usually positional, often brought on by activities such as standing or walking and relieved by sitting down.

Spinal nerve roots branch outward from the spinal cord through passageways called neural foramina comprised of bone and ligaments. Between each set of vertebral bodies, located on the left and right sides, is a foramen. Nerve roots pass through these openings and extend outward beyond the spinal column to innervate other parts of the body. When these passageways become narrow or clogged causing nerve compression, the term foraminal stenosis is used.

What Is Spinal Stenosis?

A clue to answering this question is found in the meaning of each word. Spinal refers to the spine. Stenosis is a medical term used to describe a condition where a normal-size opening has become narrow. Spinal stenosis may affect the cervical (neck), thoracic (chest), or lumbar (lower back) spines.

The most commonly area affected is the lumbar spine followed by the cervical spine.

Visualize Spinal Stenosis?

Consider a water pipe. Over time, rust and debris builds up on the walls of the pipe, thereby narrowing the passageway that normally allows water to freely flow. In the spine, the passageways are the spinal canal and the neuroforamen. The spinal canal is a hollow vertical hole that contains the spinal cord. The neuroforamen are the passageways that are naturally created between the vertebrae through which spinal nerve roots exit the spinal canal.

sciatica causeThe neuroforamen are the passageways that are naturally created between the vertebrae through which spinal nerve roots exit the spinal canal.

Illustration above: The spine’s bony structures encase and protect the spinal cord. Small nerve roots shoot off from the spinal cord and exit the spinal canal through passageways called neuroforamen.

Lumbar (low back) spinal stenosis is illustrated below. Notice the narrowed areas in the spinal canal (reddish-colored areas). As the canal space narrows, the spinal cord and nearby nerve roots are squeezed causing different types of symptoms. The medical term is nerve compression.

sciatica causeAnatomy Overview Can Help You Understand Spinal Stenosis

The spine is a column of connected bones called vertebrae. There are 24 vertebrae in the spine, plus the sacrum and tailbone (coccyx). Most adults have 7 vertebrae in the neck (the cervical vertebrae), 12 from the shoulders to the waist (the thoracic vertebrae), and 5 in the lower back (the lumbar vertebrae). The sacrum is made up of 5 vertebrae between the hipbones that are fused into one bone. The coccyx is made up of small fused bones at the tail end of the spine.

Lamina and Spinous Processes: At the back (posterior) of each vertebra, you have the lamina, a bony plate that protects your spinal canal and spinal cord. Your vertebrae also have several bony tabs that are called spinous processes; those processes are attachment points for muscles and ligaments.

Ligaments, Especially the Ligamentum Flavum: Vertebrae are connected by ligaments, which keep the vertebrae in their proper place. The ligamentum flavum is a particularly important ligament. Not only does it help stabilize your spine, it also protects your spinal cord and nerve roots. Plus, the ligamentum flavum is the strongest ligament in your spine.

The ligamentum flavum is a dynamic structure, which means that it adapts its shape as you move your body. When you’re sitting down and leaning forward, the ligamentum flavum is stretched out; that gives your spinal canal more room for the spinal nerves. When you stand up and lean back, though, the ligamentum flavum becomes shorter and thicker; that means there’s less room for the spinal nerves. (This dynamic capability helps explain why people with spinal stenosis find that sitting down feels better than standing or walking.)

Discs: In between each vertebra are tough fibrous shock-absorbing pads called the intervertebral discs. Each disc is made up of a tire-like outer band (annulus fibrosus) and a gel-like inner substance (nucleus pulposus).

Spinal Nerves and the Spinal Cord: Nerves are also an important part of your spinal anatomy�after all, they’re what sends messages from your brain to the rest of your body. The spinal cord, the thick bundle of nerves that extends downward from the brain, passes through a ring in each vertebra. Those rings line up into a channel called the spinal canal.

Between each vertebra, two nerves branch out of the spinal cord (one to the right and one to the left). Those nerves exit the spine through openings called the foramen and travel to all parts of your body.

sciatica causeNormally, the spinal channel is wide enough for the spinal cord, and the foramen are wide enough for the nerve roots. But either or both can become narrowed, and cause spinal stenosis.

Sciatica Cause #3: Spondylolisthesis

Spondylolisthesis is a disorder that most often affects the lumbar spine. It is characterized by one vertebra slipping forward over an adjacent vertebra. When a vertebra slips and is displaced, spinal nerve root compression occurs and often causes sciatic leg pain. Spondylolisthesis is categorized as developmental (found at birth, develops during childhood) or acquired from spinal degeneration, trauma or physical stress (eg, lifting weights).

Spondylolisthesis occurs when one vertebra slips forward over the vertebra below it. The term is pronounced spondy-low-lis-thesis and is derived from the Greek language: spondylo means vertebra and listhesis means to slip. There are several types or causes of spondylolisthesis; a few are listed below.

sciatica cause

 

  • Congenital spondylolisthesis means the disorder is present at birth.
  • Isthmic spondylolisthesis occurs when a defect, such as a fracture occurs in a bony supporting vertebral structure at the back of the spine.
  • Degenerative spondylolisthesis is more common and is often associated with degenerative disc disease, wherein the discs (eg, due to the effects of growing older) lose hydration and resilency.

How Spondylolisthesis May Develop

The lumbar spine is exposed to directional pressures while it carries, absorbs, and distributes most of your body’s weight at rest and during activity. In other words, while your lumbar spine is carrying and absorbing body weight, it also moves in different directions (eg, rotate, bend forward). Sometimes, this combination causes excessive stress to the vertebra and/or its supporting structures, and may lead to a vertebral body slipping forward over the vertebrae beneath.

Who May Be At Risk

If a family member (eg, mother, father) has spondylolisthesis, your risk for developing the disorder may be greater. Some activities make you more susceptible to spondylolisthesis. Gymnasts, linemen in football, and weight lifters all put significant pressure and weight on their low backs. Think about gymnasts and the positions they put their body in: They practically bend in half backwards�that’s an extreme arched back. They also twist through the air quickly when doing flips and then land, absorbing the impact through their legs and low back. Those movements put substantial stress on the spine, and spondylolisthesis can develop as a result of repeated excessive strains and stress.

X-Ray View Of Spondylolisthesis

The x-ray below shows you a good example of a lumbar spondylolisthesis. Look at the area the arrow is pointing to: You can see that the vertebra above the arrow isn’t in line with the vertebra below it. It’s slipped forward; it’s spondylolisthesis.

sciatica causeArrow Points To A Lumbar Spondylolisthesis

Grading Spondylolisthesis

Doctors “grade” the severity of a spondylolisthesis using five descriptive categories. Although there are several factors your doctor considers when evaluating your spondylolisthesis, the grading scale (below) is based on the far forward a vertebral body has slid forward over the vertera beneath. Often, the doctor uses a lateral (side view) x-ray to examine and grade a spondyloisthesis. Grade I is a smaller slip than Grade IV or V.

  • Grade I: Less than 25% slip
  • Grade II: 25% to 49% slip.
  • Grade III: 50% to 74% slip.
  • Grade IV: 75% to 99% slip.
  • Grade V: The vertebra that has fallen forward off the vertebra below it. This is the most severe type of spondylolisthesis and is termed spondyloptosis.

Sciatica Cause #4: Trauma

Sciatica can result from direct nerve compression caused by external forces to the lumbar or sacral spinal nerve roots. Examples include motor vehicle accidents, falling down, football and other sports. The impact may injure the nerves or, occasionally, fragments of broken bone may compress the nerves.

Sciatica Cause #5: Piriformis Syndrome

Piriformis syndrome is named for the piriformis muscle and the pain caused when the muscle irritates the sciatic nerve. The piriformis muscle is located in the lower part of the spine, connects to the thighbone, and assists in hip rotation. The sciatic nerve runs beneath the piriformis muscle. Piriformis syndrome develops when muscle spasms develop in the piriformis muscle thereby compressing the sciatic nerve. It may be difficult to diagnose and treat due to the lack of x-ray or magnetic resonance imaging (MRI) findings.

If you�ve ever felt pain in the hip, pain in the center of the butt, or pain down the back of the leg, you are likely suffering, at least partially, with piriformis syndrome. The piriformis is a muscle which runs from your sacrum (mid-line base of spine) to the outer hip bone (trochanter). This muscle truly works overtime on anyone who runs at all.

sciatica causeThe muscles in and around the gluteal region help with three areas

  • rotation of the hip and leg;
  • balance while one foot is off the ground; and
  • stability for the pelvic region.

Needless to say, all of these characteristics are highly needed by runners (and everyone else, when you come to think of it).

Injuries To The Piriformis

This muscle is a prime candidate for repetitive motion injury (RMI). RMI occurs when a muscle is asked to perform beyond it�s level of capability, not given enough time to recover, and asked to perform again. The typical response from a muscle in this situation is to tighten, which is a defensive response of the muscle. This tightness, however, manifests itself in several ways to a runner.

The first symptom suggesting piriformis syndrome would be pain in and around the outer hip bone. The tightness of the muscle produces increased tension between the tendon and the bone which produces either direct discomfort and pain or an increased tension in the joint producing a bursitis. Again, a bursitis is an inflammation of the fluid filled sac in a joint caused by an elevation of stress and tension within that joint.

The second symptom suggesting piriformis syndrome would be pain directly in the center of the buttocks. Although this is not as common as the other two symtpoms, this pain can be elicited with direct compression over the belly of the buttocks area. A tight muscle is a sore muscle upon compression due to a reduced blood flow to that muscle.

The third symptom suggesting piriformis syndrome would be a sciatic neuralgia, or pain from the buttocks down the back of the leg and sometimes into different portions of the lower leg. We have an article that can teach you more about how piriformis syndrome and sciatica are related.

The sciatic nerve runs right through the belly of the piriformis muscle and if the piriformis muscle contracts from being overused, the sciatic nerve now becomes strangled, producing pain, tingling and numbness.

Simple Physiology

Any muscle repetitively used needs to have an opportunity to recover. This recovery can either be on Nature�s clock, or can be facilitated and sped up with proper knowledge and treatment. Since the muscle is tightening due to overuse, continued use will only make it worse. This injured muscle needs to relax and have increased blood flow encouraged to it for more rapid healing. This tightness that exists also reduces the normal blood flow going to the muscle reducing the speed with which the muscle can recover. To encourage fresh, oxygen-rich blood to the muscle is the most powerful means of getting the muscle to begin to relax and function normally. Multiple massages per day to this area is greatly encouraged.

The next step in this “recovery” process is to use a tennis ball under the butt and hip area. While sitting down on the floor, roll away from the side of involvement and place a tennis ball just inside the outer hip bone under the butt area. As you begin to allow your weight onto the tennis ball, note areas of increased pain and soreness. Trigger points will tend to accumulate in a repetitively used muscle, and until these toxins are manually broken up and eliminated, the muscle will have an artificial ceiling with regard to flexibility potential and recovery potential. So, if it�s sore and hurts while your sitting on it, you�re doing a good job. Let the ball work under each spot for 15-20 seconds before moving it to another area. Once you�ve been on the ball for 4-5 minutes, now put the ankle of the involved leg over the knee of the non-involved leg (crossing your legs). Now place the tennis ball just inside the outer hip bone again and work the tendon of the piriformis muscle. While this pain is typically excruciating and takes some time to effectively reduce, the benefits here are huge. Be patient, be consistent and good things will happen.

Additional Treatments

Due to the fact that the sciatic neuralgia and the hip bursitis or tendonitis are both inflammatory in nature, ice, or cryotherapy, over the involved area 15-20 minutes at a time will be beneficial. This should be done multiple times per day.

Stretching of the hip muscles should not be done until the acute pain is gone. At that point in time, begin with gentle stretching, such as the cross-legged stretch while pulling up on the knee. The muscle should have increased flexibility before an active return to running.

Finally, I�m always discouraging the use of pharmaceutical anti-inflammatories. Not only do they greatly aggravate the intestines, but they also suggest an artificial wellness that can lead to bigger problems. Proteolytic enzymes, such as bromelain, are both natural and extremely beneficial with no side effects.

Conclusion: The piriformis muscle is pretty important for all of us.

Sciatica Cause #6: Spinal Tumors

Spinal tumors are abnormal growths that are either benign or cancerous (malignant). Fortunately, spinal tumors are rare. However, when a spinal tumor develops in the lumbar region, there is a risk for sciatica to develop as a result of nerve compression.

If you think you have sciatica, call your doctor or chiropractor. The first step toward relieving pain is a proper diagnosis.

Written by Jean-Jacques Abitbol, MD; Reviewed by Brian R. Subach, MD

Howard S. An, MD, Stewart G. Eidelson, MD; Reviewed by Howard S. An, MD, Jason M. Highsmith, MD

Timothy J. Maggs, D.C.; Reviewed by Edward C. Benzel, MD

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Traditional Chinese Medicine for Low Back Pain Due to Lumbar Disc Herniation

Traditional Chinese Medicine for Low Back Pain Due to Lumbar Disc Herniation

Understanding the following, traditional Chinese medicine utilizes herbal medicines as well as various mind and body practices, such as acupuncture and tai chi, in order to treat or prevent numerous health issues. Traditional Chinese medicine, or TCM, originated in ancient China and has evolved over thousands of years. TCM has been primarily used as a complementary health approach along with other alternative treatment options like chiropractic care. Like TCM, chiropractic care is an alternative healthcare approach focused on the diagnosis, treatment and prevention of a variety of injuries and conditions of the musculoskeletal and nervous system, with an emphasis on manual manipulations and adjustments of the spine. As a doctor of chiropractic, or DC, TCM can also be offered to treat various types of injuries and conditions.

 

On a personal note, integrative TCM conservative therapies have been utilized to help treat symptoms of low back pain due to lumbar disc herniation, or LDH. Disc material from a ruptured or herniated disc in the lumbar spine can irritate or compress one or several of the nerves found in the lower spine. Pressure along the sciatic nerve can cause symptoms of sciatica, such as pain and discomfort, burning and tingling sensations, and numbness which may radiate from the buttocks into the leg and occasionally, down to the foot.�A randomized controlled trial was conducted in order to measure the outcomes of traditional Chinese medicine for low back pain due to LDH. The results have been recorded below.

 

Abstract

 

Low back pain due to lumbar disc herniation (LDH) is very common in clinic. This randomized controlled trial was designed to investigate the effects of integrative TCM conservative therapy for low back pain due to LDH. A total of 408 patients with low back pain due to LDH were randomly assigned to an experimental group with integrative TCM therapy and a control group with normal conservative treatment by the ratio of 3?:?1. The primary outcome was the pain by the visual analogue scale (VAS). The secondary outcome was the low back functional activities by Chinese Short Form Oswestry Disability Index (C-SFODI). Immediately after treatment, patients in the experimental group experienced significant improvements in VAS and C-SFODI compared with the control group (between-group difference in mean change from baseline, ?16.62 points, P < 0.001 in VAS; ?15.55 points, P < 0.001 in C-SFODI). The difference remained at one-month followup, but it is only significant in C-SFODI at six-month followup (?7.68 points, P < 0.001). No serious adverse events were observed. These findings suggest that integrative TCM therapy may be a beneficial complementary and alternative therapy for patients with low back pain due to LDH.

 

Introduction

 

Lumbar disc herniation (LDH) is a common disease and a major contributing factor of low back pain. Although many studies have confirmed that surgery is more effective for LDH, conservative therapies have also been recognized for their therapeutic efficacy. Considering the fact that 20% of patients still have pain after surgery, 7% to 15% of surgical patients may have failed back surgery syndrome, and some patients are scared of surgery, conservative treatment is still one of the primary means for LDH.

 

In China, TCM is one of the main conservative treatments for LDH. Previous studies have confirmed that some TCM therapies have certain effects on low back pain due to LDH. These include acupuncture, oral administration of Chinese medicine, external application of Chinese medicine, Chinese Tuina (massage), and TCM-characteristic functional exercise. Clinically, these therapeutic methods are not used alone but often in combination. Recently, the clinical pathway of treating LDH with integrative TCM therapy has attracted attention. The Shi’s Traumatology Medical Center of Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine is well recognized for its long-term commitment to the research on conservative treatment for LDH, coupled with a package protocol for LDH. However, high-quality research evidence is needed to support the effectiveness of the protocol.

 

This clinical trial aims to study the efficacy and safety of integrative TCM therapy for LDH and thus confirm its clinical effect.

 

Materials and Methods

 

Design

 

We conducted a multicenter, randomized controlled trial to evaluate the effectiveness of integrative TCM conservative treatment for patients with low back pain due to LDH. Patients were randomly assigned to an experimental group and a control group by the ratio of 3?:?1 using computer-generated numbers. The randomized treatment assignments were sealed in opaque envelopes and opened individually for each patient who agreed to be in the study. The nurse, who had no role in the design and conduct of the study, prepared the envelopes. Patients in the experimental group were treated with integrative TCM therapy once a day, for two weeks, whereas patients in the control group were treated with a two-week normal conservative intervention. At baseline, immediately after treatment, one and six months after treatment, visual analogue scale (VAS) and the Chinese Short Form Oswestry Disability Index (C-SFODI) were used as outcome assessment. This trial is registered in Chinese Clinical Trial Registry (No. ChiCTR-TRC-11001343).

 

Subjects

 

Patients were recruited from Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Ruijin Hospital Affiliated to Shanghai Jiaotong University, and Yueyang Integrative Traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine between January 2011 and August 2012.

 

Inclusion criteria: (1) aging 20�60 years; (2) having low back pain due to LDH (MRI scan confirmed lumbar disk herniation) and ruling out other relevant ongoing pathologies such as fractures, lumbar spondylolisthesis, tumor, osteoporosis, or infection; (3) willing to participate in this study and signing the informed consent.

 

Exclusion criteria: (1) having other pain syndromes; (2) experiencing a history of spinal surgery; (3) having neurological disease; (4) having psychiatric disease; (5) having serious chronic diseases that could interfere with the outcomes (e.g., cardiovascular disease, rheumatoid arthritis, epilepsy, or other disqualifying conditions); (6) scared of acupuncture; (7) pregnant or planning to become pregnant during the study; (8) having other diseases that the researchers believe is not suitable for the study.

 

Treatment

 

Experimental Group

 

Patients in the experimental group receive a two-week integrative TCM treatment. They were further divided into three subgroups (according to the duration from initial low back pain to getting treatment) for different treatment methods: acute stage (0�14 days), subacute stage (15�30 days), and chronic stage (>30 days).

 

Acute stage: (1) Electroacupuncture + (2) Chinese herbal injection (Salvia miltiorrhiza injection) + (3) external plaster (Compound Redbud Injury-healing Cataplasms); Subacute stag: (1) Chinese Tuina (massage) + (2) hot compress using Chinese medicine + (3) external plaster (Compound Redbud Injury-healing Cataplasms); Chronic stage: (1) TCM functional exercise + (2) external plaster (Compound Redbud Injury-healing Cataplasms).

 

Treatment Parameters

 

Electroacupuncture. Points: bilateral Dachangshu (BL 25) and Baihuanshu (BL 30).

 

Method: Insert the needles (the sterile, disposable needles, 0.3 � 75?mm, manufactured by Suzhou Medical Supplies Factory Co., Ltd.) 2.5 to 2.8?cun. Upon De Qi (needling sensation), connect the needles with the electroacupuncture device (Model: G6805-II, manufactured by Guangzhou KangMai Medical Devices Co., Ltd.), using a continuous wave, an electrical stimulation pulse wave of approximately 0.6?ms and a frequency of 20?Hz. The treatment was conducted once every day, 30?min for each treatment.

 

External Plaster. Compound Redbud Injury-healing Cataplasms (Approval no. Z19991106, manufactured by Shanghai LEY’s Pharmaceutical Co., Ltd.).

 

Main ingredients: Zi Jing Pi (Cortex Cercis Chinensis), Huang Jing Zi (Negundo Chastetree Fruit), Da Huang (Radix et Rhizoma Rhei), Chuan Xiong (Rhizoma Chuanxiong), Tian Nan Xing (Rhizoma Arisaematis), and Ma Qian Zi (Semen Strychni).

 

Functions: Circulates blood, resolves stasis, eliminates swelling, and alleviates pain.

 

Method: Apply the cataplasms to the most painful area, one plaster each time, once a day.

 

Chinese Herbal Injection. Salvia miltiorrhiza injection (Approval no. Z51021303, manufactured by Sichuan ShengHe Pharmaceutical Co., Ltd.).

 

The main ingredient of the injection is Salvia root P.E. It acts to circulate blood and resolve stasis.

 

Method: Intravenous dripping of 20?mL salvia miltiorrhiza injection and 250 mL 5% glucose, once a day.

 

Hot Compress Using Chinese Medicine. Ingredients: 20?g of Cang Zhu (Rhizoma Atractylodis), Qin Jiao (Radix Gentianae Macrophyllae), Sang Zhi (Ramulus Mori), Mu Gua (Fructus Chaenomelis), Hong Hua (Flos Carthami), Chuan Xiong (Rhizoma Chuanxiong), Hai Feng Teng (Caulis Piperis Kadsurae) and Lei Gong Teng (Radix Tripterygii Wilfordii), respectively. All herbs were provided by Shanghai Hongqiao Pharmaceutical Co., Ltd. and have been tested and qualified.

 

Method: Place the previous medicinal into a gauze bag, decoct with water for 20?mins and take it out. After the temperature cooled to 40~45�C, apply the back to the affected low back area for 30�40 minutes, once a day. The hot compress can help circulate blood and resolve stasis.

 

TCM Functional Exercise. The exercise is known as �Fei Yan Shi� (literally meaning �the flying swallow style�) in Chinese.

 

Method: Ask the patient to take a prone position, extend both hands backwards, lift the chest and lower limbs off the bed using the abdomen as a pivot, and then relax. Conduct this exercise once a day and repeat 4-5 times each time.

 

Functions: Strengthens the power of back muscles, increases the stability of the spine, and thus prevents relapses.

 

Chinese Tuina (Massage). Ask the patient to take a prone position and find the tenderness spots on the low back. Then apply gun-rolling (10?min), Anrou-pressing and kneading (10?min), and Tanbo-plucking (5?min) manipulation to the tenderness spots and surrounding areas. Conclude with oblique pulling manipulation of the low back. Conduct the treatment once a day.

 

Functions: Relaxes spasm of the low back muscles and adjusts lumbar subluxation.

 

After one week TCM treatment, if the patient’s lower back pain without any relief or even aggravated, the prescription of pain medication was adjusted according to clinical guidelines, detailed records the type and dose of pain medication taken by patients, and the patient was identified as no effect.

 

Control Group

 

Patients in the control group receive a two-week normal conservative treatment. Intervention measures include three sections, (1) health education. The patients were invited to receive LDH health education twice a week in outpatient; the health education was designed exclusively to inform patients about the natural course of their illness and the expectation of successful recovery, irrespective of the initial intensity of their pain, educate patients to avoid some bad habits that aggravate the disease, such as a sitting position for a long time and carrying heavy loads, and encourage patients to participate in social activities. (2) Rest: in addition to the normal sleep, the patients need to rest in bed for at least 1-2 hours a day. (3) Pain medication or physical therapy: after one week health education, if the patient’s lower back pain without any relief or even aggravated, the prescription of pain medication was adjusted according to clinical guidelines, detailed records the type and dose of pain medication taken by patients. And if the patients do not want to take pain medication, then the patients were referred to a physiotherapist.

 

Measurements

 

All outcomes were assessed by observers unaware of the grouping, at baseline (M1), immediately after the last intervention (M2). The followup included the assessments at one month (M3) and six months (M4) after the last intervention.

 

The primary outcome measure was the change in pain by the visual analogue scale (VAS), scores range 0 to 100, and a higher score indicates a greater pain, 0 means no pain, and 100 means intolerable pain.

 

The secondary outcome measure was the change in the Chinese Short Form Oswestry Disability Index (C-SFODI), range 0 to 100%. The C-SFODI consists of nine questions, which come from Oswestry Disability Index (ODI); omit the sex life question in Section??8, because this question is always unacceptable by Chinese. The C-SFODI calculation formula is actual cumulative score/45 � 100%, with higher percentage indicating more severe functional disability. And the study has shown that the C-SFODI has good reliability and validity.

 

Statistical Analysis

 

Our pretrial power calculation indicated that 81 patients in experimental group were required to detect a difference in pain relief based on the preliminary experiment data at a significant level of 5% (a two-sided t-test) with 80% power. In anticipation of a 20% attrition rate, we sought 102 patients at least in experimental group. Taking into account the poor effect of control therapy, 102 patients were included in the control group.

 

Between-group difference at baseline was analyzed using independent-samples t-test or Chi-square test. Changes in continuous measures were analyzed by analysis of variance (ANOVA). Effects were evaluated on an intention-to-treat basis (ITT), and participants who did not complete the followup period were considered not having any changes in scores. A two-sided P value of less than 0.05 indicated statistical significance. Results are presented as mean and standard deviation (SD) at M1 and as between-group difference with 95% confidence intervals (CI) at M2, M3, and M4.

 

Quality Control

Before the beginning of the study, all researchers have to receive protocol training. A clinic research coordinator (CRC) was employed to assist researchers in each center. A monitor was also appointed to ensure the quality of the research.

 

Dr. Alex Jimenez’s Insight

The above clinical trial focused on investigating the safety and effectiveness of TCM, or traditional Chinese medicine, for low back pain due to lumbar disc herniation as well as to confirm its clinical result. The participants of the research study with low back pain due to LDH were divided into two groups: the experimental group, which was treated with integrative TCM conservative therapy; and the control group, which was treated normal conservative treatment. The experimental group was then further divided into three subgroups. The details of each TCM treatment method used in the subgroups, including the name, ingredients, method and function of each, are described above. The outcomes were measured accordingly by observers unaware of the specific group divisions. The statistic results were properly analyzed by researchers who received protocol training before the start of the study.

 

Results

 

Between January 2011 and August 2012, a total of 480 patients with low back pain due to LDH were recruited, 72 were rejected due to exclusion criterions, and 408 eligible patients were randomly assigned in accordance with the ratio of 3?:?1 to the experimental group and the control group, 306 in the experimental group and 102 in the control group. Patients in the experimental group all completed a two-week treatment. In the control group, at the second week one patient in the control group was unwilling to continue to participate and withdrew his informed consent, and two patients took Fenbid (500?mg for each dose, 2 doses a day) since the pain worsened during treatment (Figure 1).

 

Figure 1 Screening with Randomization and Completion Evaluations

Figure 1: Screening, randomization, and completion evaluations from the baseline to six-month followup, LDH = lumbar disc herniation.

 

Baseline Characteristics of the Patients

 

Table 1 shows the baseline data for the 408 participants. The mean age of all patients is 45 years, and 51% were women. In terms of disease staging, experimental group and control group were comparable. And the baseline outcome including VAS scores and C-SFODI were also reasonably well balanced between experimental group and control group.

 

Table 1 Baseline Characteristics of the Study Participants

Table 1: Baseline characteristics of the study participants.

 

Improvement in the Primary Outcome

 

The changes in the primary outcomes from baseline to six-month followup are shown in Table 2 and Figure 2. Immediately after the intervention, two groups showed significant decrease in VAS than the baseline. And the experimental group showed a more significant decrease than the control group (?16.62 points [95% confidence interval {CI}, ?20.25 to ?12.98]; P < 0.001).

 

Figure 2 Mean Changes of the Primary and Secondary Outcomes

Figure 2: Mean changes of the primary and secondary outcomes. The means of outcomes are shown for the experimental group (diamond) and the control group (squares). Measurements were obtained at baseline (M1), immediately after the last intervention (M2).

 

Table 2 Changes in Primary and Secondary Outcomes

Table 2: Changes in primary and secondary outcomes.

 

One month after intervention, two groups also had significantly greater reduction in VAS than the baseline. And again, the experimental group showed a more significant decrease than the control group (?6.37 points [95% CI, ?10.20 to ?2.54]; P = 0.001).

 

Six months after intervention, compared with the baseline, the changes in VAS remained significant in the experimental group and control group, but between-group difference was not significant (P = 0.091).

 

Improvement in the Secondary Outcome

 

Immediately after intervention, two groups had significant improvement in C-SFODI than the baseline, and the experimental group showed a more significant improvement than the control group (?15.55 points [95% CI, ?18.92 to ?12.18]; P < 0.001).

 

One month after intervention, two groups also had significant improvement in C-SFODI than the baseline. And again, the experimental group improved more (?11.37 points [95% CI, ?14.62 to ?8.11]; P < 0.001).

 

Six months after intervention, two groups also maintained significant improvement, and the experimental group showed superiority (?7.68 points [95% CI, ?11.42 to ?3.94]; P < 0.001).

 

Adverse Events

 

One patient in the experiment group had mild fainting during acupuncture, remission by bed rest, and then completed the remaining treatment. Two patients in the control group were given Fenbid orally due to aggravated low back pain. No other adverse events were noted in either experimental group or control group.

 

Discussion

 

Although the mechanism of low back pain caused by lumbar disc herniation (LDH) is still not very clear, the prevailing view is that low back pain due to LDH was found to occur not only in response to mechanical stimuli but also to chemical irritation around the nerve root sheath and sinuvertebral nerve.

 

Different TCM therapies have different advantages in the treatment of LDH. Pain is the main symptom in the acute stage of LDH; acupuncture has good analgesic effect on low back pain due to LDH. Lumbar dysfunction is the main symptom in the remission stage; Chinese massage has good effect on improving dysfunction. Oral Chinese herbal formulae, external use of Chinese medicine, and Chinese herbal injection also showed good effect in relieving pain and improving dysfunction caused by LDH. And one study also found that Salvia miltiorrhiza injection especially works better and faster for the acute stage when compared with mannitol. Although the mechanism of acupuncture, Chinese massage, and traditional Chinese herbs in the treatment of LDH remains unclear, it is generally agreed that these treatment methods play a role by increasing local blood circulation, relieving nerve root edema, and speeding up the metabolism of the local inflammatory mediators. In recovery stage of the disease, the major task is to strengthen the muscles of the waist and abdomen to prevent relapse, and TCM functional exercise has advantages in this regard and can subsequently increase the lumbar stability to prevent recurrence.

 

Treating LDH according to different stages has been more and more accepted. In China, LDH is mainly divided into three stages, including acute stage, subacute stage (or remission stage), and chronic stage (or recovery stage). Studies have proven that treating LDH according to different stages has obtained a good clinical effect. In addition, studies have also suggested that it can obtain a better effect than treatment without differentiating different stages.

 

The past 20 years of clinical practice have witnessed the safety of the treatment regimens used in this study. At the same time, its efficacy has been preliminarily confirmed; however, high quality research evidence is still needed. In the treatment regimens, different TCM therapies were selected according to the characteristics of different stages. Specifically, acupuncture and Chinese herbal injections were used in the acute stage for fast pain relief, Chinese Tuina (massage) and external application of Chinese medicine were used in the subacute stage for improvement of the lumbar functions, and low back muscle exercise was used in the chronic stage to increase the stability of the spine and prevent relapses.

 

In China, nonsurgical treatment of lumbar disc herniation mainly uses drugs, physical therapy, or TCM treatment. TCM treatment used in the experimental group has been used in clinical routine and is considered to have good clinical efficacy; the efficacy of conservative treatment used in the control group is considered very weak, usually as auxiliary treatment of other therapies. Ethics Committee considers that in order to maximize the protection of the interests of the patients, it is necessary to let the patients have more opportunity to receive TCM treatment, so in this research the sample size of the experimental group and the control group is 3?:?1.

 

The findings of this study have shown that immediately and one month after intervention, integrative TCM conservative treatment can significantly reduce the VAS scores and C-SFODI, and at six month after intervention, integrative TCM conservative treatment can also significantly reduce the C-SFODI, but two groups have no significant difference in reducing VAS score. VAS is an international general pain visual analog scale, and C-SFODI is the improved version of the ODI (Oswestry Disability Index), and it consists of 9 questions, a higher percentage indicating a more severe functional disability.

 

Regarding adverse events, one patient had mild fainting in the experiment group, two patients in the control group were given Fenbid oral due to low back pain aggravation, and no other adverse events were noted in either experimental group or control group. The mechanism of integrative TCM conservative treatment for LDH remains unclear, and it will be our future research orientation.

 

The main limitation of this study is the short followup time. As a result, we failed to conduct comprehensive evaluation regarding the long-term efficacy of integrative TCM conservative treatment for LDH.

 

Conclusions

 

This randomized controlled clinical trial provides reliable evidence regarding the effectiveness of integrative TCM conservative treatment for patients with low back pain due to lumbar disc herniation. A large sample of long-term followup is further needed for future research.

 

Conflict of Interests

 

No potential conflict of interests relevant to this study was reported.

 

Acknowledgments

 

This work is supported by the Key Discipline of TCM Orthopaedic and Traumatic of the Ministry of Education of the People’s Republic of China (100508); the Medical Key Project of Shanghai Science and Technology Commission (09411953400); the project of Shanghai Medical leading talent (041); the National Natural Science Foundation of China (81073114, 81001528); the National Key New Drugs Creation Project, innovative drug research and development technology platform (no. 2012ZX09303009-001); Shanghai University Innovation Team Construction Project of the Spine Disease of Traditional Chinese Medicine (2009-26).

 

In conclusion, with the measured outcomes and final results of the two groups of participants with low back pain due to lumbar disc herniation, the randomized controlled trial helped contribute valuable information regarding the safety and effectiveness, as well as the clinical effect of integrative TCM conservative therapy. Information referenced from the National Center for Biotechnology Information (NCBI). The scope of our information is limited to chiropractic as well as to spinal injuries and conditions. To discuss the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .

 

Curated by Dr. Alex Jimenez

 

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Additional Topics: Sciatica

 

Sciatica is referred to as a collection of symptoms rather than a single type of injury or condition. The symptoms are characterized as radiating pain, numbness and tingling sensations from the sciatic nerve in the lower back, down the buttocks and thighs and through one or both legs and into the feet. Sciatica is commonly the result of irritation, inflammation or compression of the largest nerve in the human body, generally due to a herniated disc or bone spur.

 

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IMPORTANT TOPIC: EXTRA EXTRA: Treating Sciatica Pain

 

 

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Electroacupuncture vs. Medium-Frequency Electrotherapy for Sciatica

Electroacupuncture vs. Medium-Frequency Electrotherapy for Sciatica

Electroacupuncture: Before reviewing the data below, it is important as a practicing doctor of chiropractic to inform that�sciatica and discogenic lower back pain are two closely related health issues which collectively, can be a source of painful symptoms and discomfort as well as a cause of limited mobility among affected individuals. Discogenic disease, also known as degenerative disc disease, is characterized as the naturally-occurring deterioration of the spinal intervertebral discs. While discogenic disease commonly develops with age, other factors, such as injury can also lead to degenerative disc disease. In addition, degenerative disc disease may cause other complications including bulging or herniated discs

Furthermore, from years of experience caring for patients with this health issue, bulging or herniated discs are not necessarily the cause of the individual’s pain and discomfort. Symptoms are instead the result of compression or irritation from displaced disc material against the spinal cord or an exiting nerve root. Sciatica occurs if the nerve being compressed or irritated is the sciatic nerve, the largest nerve in the human body which branches off the lower spine, down into the legs. Two methods of treatment, electroacupuncture and medium-frequency electrotherapy were used in the following research study to determine whether symptoms of sciatica would improve with one treatment therapy over the other.

Abstract

Objective. To investigate the short- and long-term effects of electroacupuncture (EA) compared with medium-frequency electrotherapy (MFE) on chronic discogenic sciatica. Methods. One hundred participants were randomized into two groups to receive EA (n = 50) or MFE (n = 50) for 4 weeks. A 28-week follow-up of the two groups was performed. The primary outcome measure was the average leg pain intensity. The secondary outcome measures were the low back pain intensity, Oswestry Disability Index (ODI), patient global impression (PGI), drug use frequency, and�electroacupuncture acceptance. Results. The mean changes in the average leg pain numerical rating scale (NRS) scores were 2.30 (1.86�2.57) and 1.06 (0.62�1.51) in the EA and MFE groups at week 4, respectively. The difference was significant (P < 0.001). The long-term follow-up resulted in significant differences. The average leg pain NRS scores decreased by 2.12 (1.70�2.53) and 0.36 (?0.05�0.78) from baseline in the EA and MFE groups, respectively, at week 28. However, low back pain intensity and PGI did not differ significantly at week 4. No serious adverse events occurred. Conclusions. EA showed greater short-term and long-term benefits for chronic discogenic sciatica than MFE, and the effect of EA was superior to that of MFE. The study findings warrant verification. This trial was registered under identifier ChiCTR-IPR-15006370.

Introduction: Electroacupuncture

Sciatica is defined as radicular leg pain localized to the dermatological distribution of a pathologically affected nerve root. Almost all discogenic sciatica is induced by lumbar disc herniation (LDH) and may be accompanied by neurological deficits, such as leg pain, leg paresthesia, disability, and low back pain. The estimated prevalence of sciatica ranges from 1.2 to 43% in various regions. Discogenic sciatica, which accounts for nearly 90% of sciatica, is a major cause of morbidity; moreover, it has a considerable impact on the economy due to both loss of work and the high costs of health care and societal support for the affected individual and his/her family. Current treatments for discogenic sciatica primarily include surgical and conservative treatments. Although discectomy is a more effective treatment than other treatments for patients with severe discogenic sciatica, in patients with less severe symptoms, surgery or conservative treatments appear to be equally effective. Discectomy should be avoided during initial treatment due to its high cost and its association with a higher incidence of postoperative complications, such as the loss of spine stability and extensive peridural fibrosis. Conservative measures comprise the first-line treatment strategy for managing radicular pain due to disc herniation. Regarding cost-effectiveness, the regimes that employ stepped approaches based on an initial treatment with conservative management have been recommended. However, many conservative treatments have no explicit curative effect, such as benzodiazepines, corticosteroids, traction, and spinal manipulation, which may be ineffective or less effective. Moreover, the long-term efficacy of analgesic drugs is not enduring, and intolerable side-effects, such as addiction, stomach ulcers, and constipation, occur frequently in patients with discogenic sciatica. Thus, based on recent information, the short- and long-term efficacy of conservative treatment should be evaluated.

Electroacupuncture (EA) has been used to treat sciatica for many decades in China. Several studies have reported that electroacupuncture EA may effectively treat neuropathic pain and relieve sciatica symptoms. However, no clear clinical evidence exists to support the application of acupuncture or�electroacupuncture in the treatment of discogenic sciatica according to the guideline for the diagnosis and treatment of lumbar disc herniation. Recently, two meta-analyses concerning sciatica treatment with acupuncture showed that previous studies on acupuncture were flawed and that the strength of the evidence was suboptimal; thus, studies of higher quality with longer-term follow-up are needed to clarify the long-term effect of acupuncture in sciatica patients.

 

Image of electroacupuncture being applied to patient.

 

Compared with manual acupuncture,�electroacupuncture treatment is capable of increasing the stimulation frequency and intensity in a controlled and quantifiable manner; moreover, its effect is superior to manual acupuncture for alleviating pain and improving paresthesia and dysfunction. Medium-frequency electrotherapy (MFE) is similar to transcutaneous electrical nerve stimulation (TENS) and may relieve pain and related symptoms. MFE works through electrostimulation of an electrode placed on the skin, and a battery powered device provided a small current to produce a tingling sensation. Several studies found that the effects obtained with 50?Hz EA were superior to those using 2?Hz EA. EA and MFE using the same frequency (50?Hz) at the same location were employed in another trial. The major difference between the two trial groups was the specific impact of needle penetration, with�electroacupuncture using needle penetration and MFE administered via nonpenetrating electrostimulation.

 

Image of medium frequency electrotherapy being applied to patient.

 

This study was a comparative trial that evaluated the effectiveness of electroacupuncture versus MFE for the treatment of chronic discogenic sciatica; these treatments are the most frequently used treatments for this disease in China. We explored the ability of�electroacupuncture to alleviate leg pain, low back pain, and dysfunction at various evaluation time points, which included an assessment of the long-term efficacy of electroacupuncture. We also assessed the patient global impression (PGI) and acceptance of�electroacupuncture compared with MFE and reports of adverse events.

Methods

Participants

The study commenced on May 28, 2015, and was completed by July 30, 2016, at the South Area of Guang’anmen Hospital, China Academy of Chinese Medical Sciences. Discogenic sciatica was diagnosed according to the criteria of the North American Spine Society. The inclusion criteria were as follows: (1) individuals aged 18 to 70 years; (2) participants whose sciatica symptoms correlated with magnetic resonance imaging (MRI) or computed tomography (CT) findings of lumbar disc herniation; (3) participants whose symptoms of leg pain lasted more than 3 months; (4) participants who agreed to follow the trial protocol; and (5) participants who could complete the study treatment and assessments. The exclusion criteria were as follows: (1) participants with severe progressive neurological symptoms (e.g., cauda equina syndrome and progressive muscle weakness); (2) participants who had undergone surgery for lumbar disc herniation within 6 months; (3) participants with symptoms caused by conditions other than lumbar disc herniation that might lead to radiating pain in the leg; (4) participants with pain in both legs; (5) participants with cardiovascular, liver, kidney, or hematopoietic system diseases, mental health disorders, or cancer for whom EA might be inappropriate or unsafe; (6) participants who had received EA or electrotherapy within the past week; (7) women who were pregnant or lactating; (8) participants who were participating in other clinical trials; and (9) participants with a pacemaker, metal allergy, or severe fear of needles.

Study Design

This was a single-center, prospective, controlled, randomized trial conducted in patients with chronic discogenic sciatica. This trial was approved by the Ethics Committee of Guang’anmen Hospital of China Academy of Chinese Medical Sciences (approval number 2015EC042) on May 26, 2015, and was registered on May 7, 2015, at www.chictr.org.cn/ (ref. ChiCTR-IPR-15006370). Written informed consent was obtained from each participant or their legal representative. All participants were required to be able to understand written instructions and able to complete the pain assessment forms.

Randomization and Allocation Concealment

The randomization was performed by the Drug Clinical Trial Office affiliated with Guang’anmen Hospital using a computerized random number generator. Opaque, sealed envelopes were numbered consecutively, and all the sealed envelopes were maintained by a researcher who was not involved in the treatment procedure or data analysis. After informed consent was obtained, an envelope was opened by the researcher according to the patient’s order of entry into the trial, and the assigned treatment was offered to the participant. The outcome assessors and statisticians were blinded to the allocation. Two copies of the envelopes were maintained to prevent the researchers from deviating from the randomization.

Intervention

The treatments were initiated one week after participant randomization. All participants received health education on sciatica, such as using a hard bed and losing weight. During the trial, the use of analgesic drugs or other treatments was not permitted. The details of prior drug use (including dose and time) were recorded in the medication record form. Huatuo Brand stainless steel needles (0.3 � 100?mm, Suzhou Medical Appliance Factory in China, CL) and a G6805-2 electric stimulator (Shanghai Huayi Medical Instrument in China Co., Ltd.) were used in the EA group, and the Quanrikang type J48A computerized intermediate-frequency therapy apparatus (Beijing Huayi New Technical Institute in China) was used in the MFE (control) group. The acupuncture procedures were performed in accordance with the Standards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) guidelines. EA was performed by a trained clinician with more than 2 years of experience with acupuncture manipulation. The acupuncture regimen was based on our own pilot trial and specialist consensus. The acupoints of the affected side (DaChangShu, BL25) and the bilateral JiaJi (Ex-B2) corresponding to LDH were included in the EA group. The DaChangShu (BL25) acupoint was located according to the World Health Organization Standardized Acupuncture Point Location; JiaJi (Ex-B2) is located in the lumbar region 0.5 inches lateral to the posterior median line. After the participants assumed a prone position, the needle was vertically inserted rapidly into the JiaJi (Ex-B2) points. Then, the needle was inserted to a depth of approximately 1.5 inches. The participants were expected to experience soreness and distension transmitted to the leg. The needle was inserted straight into the DaChangShu on the BL25 point to a depth of 3 inches; then, the acupuncturist manipulated the needle with a lifting, thrusting, and twirling maneuver until feelings of soreness and distension were felt and radiated to the hips and lower limbs. The electric apparatus was applied to the JiaJi (Ex-B2) and DaChangShu (BL25) acupoints with a dilatational wave using a 50?Hz frequency and a comfortably tolerated maximum current intensity.

Participants assigned to the control group received MFE, which was administered by an experienced therapist different from the one delivering the EA. The acupoints and frequencies used in the MFE group were the same as those used in the EA group. After two pairs of 107 � 72?mm electrodes were placed on the acupoints, the MFE apparatus was turned on and muscle contractions were observed under the energizing electrode. The intensity was adjusted to the maximum current intensity tolerable at a comfortable level. The treatments in both groups were performed once daily for 5 sessions/week for the first 2 weeks and followed by 3 sessions/week for the following 2 weeks, with each session lasting 20 minutes.

Data Collection

The data in the trial were obtained from the case report forms recorded by the investigator. The participants’ demographic, clinical, and radiological characteristics were recorded. The diagnosis of lumbar disc herniation was confirmed after a review of the patient’s MRI or CT scan by two experienced musculoskeletal radiologists. Additionally, the diagnosis of discogenic sciatica was confirmed after a clinical examination by a consultant orthopedic physician. Investigators entered the collected data into the case report forms. At baseline and during the treatment period, the forms were completed by the participants under the guidance of a full-time staff member. During the follow-up period (16th and 28th weeks), the participants answered the questionnaire by phone.

Clinical Assessments

The primary outcome was the change from baseline in the average leg pain numerical rating scale (NRS) score at week 4. The secondary outcomes included average leg pain intensity at weeks 1, 2, 3, 16, and 28; low back pain intensity at weeks 2, 4, 16, and 28; Oswestry Disability Index (ODI) questionnaire results at weeks 2, 4, 16, and 28; PGI of improvement at weeks 2 and 4; drug use frequency at weeks 2 and 4; and EA acceptance evaluation at week 4. Adverse events were monitored and documented during the treatment and follow-up periods based on the investigator’s inquiry and reports by the participants themselves.

Primary Outcome Measure: The change from baseline in the average leg pain NRS score was measured using an 11-point numerical rating scale assessing leg pain, with 0 representing no pain and 10 representing the most severe pain. Participants were asked to rate their average leg pain intensity over the prior 24 hours. The average leg pain NRS score at week 4 was equal to the mean value of the NRS scores obtained at the three treatment sessions during the 4th week.

Secondary Outcome Measures: The following secondary outcome measures were determined. (1) The average leg pain intensity at other time points was measured by the NRS. The methods used to measure the secondary outcomes were the same as those used to measure the primary outcome except for the evaluation point. (2) Low back pain intensity was measured using an 11-point NRS. Participants rated their low back pain over the prior 24 hours with a pain NRS. The low back pain NRS score at the time of evaluation was equal to the mean value of the NRS scores in the previous 24 hours. (3) The ODI comprises 10 questions concerning the intensity of pain and daily activities. Each item contains 6 options. A higher score change in the ODI from baseline indicated more serious dysfunction. (4) The PGI improvement score was used to evaluate the improvement in pain and functional disability, and the improvement reported by patients was assessed using a 7-point scale (1 represents greatly improved and 7 represents marked worsening). (5) The frequency of drug use was recorded. The patients’ use of medications or nonprescription drugs during the trial was evaluated using a questionnaire to assess the influence of drugs. (6) To investigate which treatment was preferred, EA or MFE acceptance was assessed at week 4. A 4-point scale was used, with 1 representing �very difficult to accept� and 4 representing �very easy to accept.� (7) Adverse events were assessed using a questionnaire at the end of treatment and active reporting by the participants during treatment.

Sample Size and Statistical Analysis

The sample size calculation was based on the mean value of the leg pain intensity NRS score. According to our pilot trial, the decreases in the mean value of the leg pain intensity NRS scores in the EA and MFE groups at week 4 were 3.41 � 3.46 and 1.57 � 1.24, respectively. Our pilot study was an independent study conducted by our research team before this study, with no crossover participants between the previous study and the current study. We used PASS Version 11.0 (International Business Machines Corporation, China) software to calculate a sample size of 50 for each group to provide 90% power to detect a difference of 1.8 between the groups with a two-sided 5% level of significance, allowing for a 20% dropout rate and with the participants receiving the treatments and completing the follow-up.

The statistical analysis was performed using SPSS Version 22.0 (International Business Machines Corporation, China) software. Two-sided tests were used for all statistical analyses. The level of significance was established at 0.05. All patients who accepted randomization were included in the analysis. All data collected from the participants were included in the statistical analysis, and missing data were replaced by the last observed value. However, the outcomes for which no data except for the baseline assessment data were available were not included in the final analysis. The 100 participants included at least 1 treatment session. Thus, we analyzed the data of all the participants as the primary outcome, which was measured after the first treatment session. However, the secondary outcomes were evaluated at week 2, and 13 participants dropped out before week 2 without any data after treatment except for leg pain NRS scores. So the 13 participants were not included in the statistical analysis of secondary outcomes. Continuous data were represented by means and standard deviations (SD) if the data were normally distributed or by the medians and interquartile ranges if the data were skewed, or by means and 95% confidence intervals (CIs); categorical data were represented by percentages or 95% CIs. For comparisons with baseline data, a paired t-test was used for continuous data and a nonparametric test was used for categorical data. To compare the two independent samples, T tests or Mann�Whitney U tests were used to compare continuous variables, and chi-square tests or Fisher’s exact tests were used to compare categorical variables, as appropriate. A repeated measures analysis of variance or nonparametric test was used to compare differences in data between the groups at multiple time points.

Results

Dr. Alex Jimenez’s Insight

The short- and long-term effects of electroacupuncture (EA) versus medium-frequency electrotherapy (MFE) were evaluated to determine which of the two treatments, if not both, could most effectively be used to help improve symptoms of sciatica associated with degenerative disc disease. The research study was conducted with the participation of a variety of patients with symptoms of discogenic sciatica, over several types of interventions. Clinical assessments and data was collected throughout two different research study outcomes in order to gather the most valuable results. Sample size and statistical analysis were also considered before analyzing the data of all the participants and recording the results. The final outcome of the research study has been described in detail below.

Recruitment

A total of 138 participants with chronic sciatica due to lumbar disc protrusion were screened, among whom 36 were rejected due to the exclusion criteria and 2 withdrew from the study. Therefore, 100 eligible patients were randomly assigned to the experimental (EA) group (n = 50) or the control (MFE) group (n = 50) at a ratio of 1?:?1. Eight participants withdrew from the study during the course of treatment due to the presence of aggravating symptoms, 1 participant exited the study due to travel, 1 participant withdrew due to an unsatisfactory curative effect, and 3 participants were lost to follow-up. In the dropout participants, no additional data except for the leg pain NRS scores were available because the evaluation period was not reached. According to the principle of ITT analysis, we analyzed the data of all 100 subjects for the leg pain NRS scores and then performed a sensitivity analysis of these 13 subjects to verify the reliability of the results. Details are provided in Figures ?1 and ?2.

 

Figure 1 Time Frame of Each Period

Figure 1: Time frame of each period. Figure 1 shows the time frame of baseline period, treatment period, and follow-up period.

 

Figure 2 Study Flow Diagram

Figure 2: Study flow diagram.

 

Characteristics of the Participants

Table 1 shows the baseline data of the 100 participants. The mean age of all patients was 52.67 � 12.72 years. The mean duration was 48 (12�120) months. The duration of 2 participants in the electroacupuncture group was one month, and the duration of 1 participant was one month in the MFE group. The baseline demographics, body measurement data, and baseline outcomes are listed in Table 1. No significant differences in baseline demographics and clinical characteristics were observed (Table 1).

Table 1 Baseline Demographic and Clinical Characteristics of the Study Population

Table 1: Baseline demographic and clinical characteristics of the study population.

Primary Outcome

The decrease in the leg pain NRS scores from baseline to week 4 differed significantly between the EA group (n = 50) and the MFE group (n = 50) (P < 0.001). As shown in Table 2, the mean change from baseline to the 4th week in the average leg pain intensity NRS score was 2.30 (1.86�2.75) in the EA group and 1.06 (0.62�1.51) in the MFE group. At four weeks, the two groups both exhibited significantly greater reductions in NRS scores compared with baseline; however, the EA group showed a more significant decrease than the MFE group (Table 2).

Table 2 Changes from Baseline in Primary Outcomes

Table 2: Changes from baseline in primary outcomes.

Secondary Outcomes

EA showed a more significant improvement in the leg pain scores at all the evaluation points compared with that observed in the MFE group (P < 0.001) (Figure 3 and Table 2). The EA group showed a significant decrease compared to the baseline in the leg pain, low back pain, and ODI scores at weeks 2, 4, 16, and 28 (all P < 0.05). Conversely, the MFE group did not show a significant improvement compared to the baseline in the low back pain score at weeks 16 and 28 (all P = 0.096). Significant reductions in the leg pain and ODI questionnaire scores were detected in the EA group at multiple time points compared with the MFE group (all P < 0.05). The EA group exhibited greater improvement. However, a negligible change was detected at multiple time points in the low back pain score and PGI between the two groups (all P > 0.05). Furthermore, no significant difference was detected in the frequency of drug use between the two groups at weeks 2 and 4 (all P > 0.05) in our trial. Consequently, an EA or MFE acceptance assessment administered after 4 weeks of intervention showed that EA was accepted as readily as MFE with no significant differences between the two groups (P = 0.055). The corresponding data are shown in Tables ?2 and ?3.

 

Figure 3 Change of Leg Pain Score in Two Groups

Figure 3: Change of leg pain score in two groups.

 

Table 3 Secondary Outcomes of the Interventions

Table 3: Secondary outcomes of the interventions.

A sensitivity analysis was performed based on the leg pain NRS score. We excluded 13 participants who received fewer treatment sessions (less than 10) and analyzed the data of the remaining 87 participants. This sensitivity analysis result showed that our original results were stable and reliable.

Adverse Events

No serious adverse events occurred in either group. One participant (2%) in the experimental group developed a subcutaneous hematoma. Two participants (4%) in the MFE group reported skin redness and itching. All adverse events disappeared without additional intervention.

Discussion

The results of this trial showed significant differences in the change in the leg pain NRS and ODI questionnaire scores in the EA group compared with those in the MFE group in the short-term treatment period and long-term follow-up. However, the EA group did not show a greater decrease in low back pain scores and PGI compared with the MFE group. These changes indicated that the effect of EA was superior to the effect of MFE in improving leg pain and dysfunction, whereas the effect of EA was not superior to that of MFE in relieving low back pain and systemic symptoms.

The leg pain NRS score showed a significant difference compared with the MFE group at week 4: a mean difference of 1.24 points was detected between the two groups. On average, a reduction of approximately 2�3.5 points in the NRS score represents a minimal clinically important difference (MCID) for acute and chronic pain. The change in the leg pain NRS score in the EA group at week 4 did not show a clinically important significant difference compared with the MFE group. However, our control group was not a placebo but a positive treatment. An effect size of 1.24 is generally considered as the large effect. The MCID of the ODI score ranged from 4 to 16 points, and the decline of the ODI score in the EA group reached the MCID criterion with a mean reduction of 5.69 compared with the MFE group. The results implied that the clinical effect of EA appears superior to the effect of MFE in improving dysfunction caused by sciatica. However, low back pain did not show a significant and clinically important difference, with a mean reduction in the NRS score of 0.58 at week 4 compared with the MFE group. It may be associated with a better response to pain around the electrodes by MFE. In our study, a long-term follow-up was performed. At week 28, the MFE group did not show significantly decreased leg pain compared to the baseline, whereas the EA group showed significantly decreased leg pain compared to the baseline. The difference between the two groups was significant. The results implied that the effect of EA but not MFE lasted at least 28 weeks. The low back pain and ODI scores also indicated that the long-term effects of EA were superior to those of MFE because the effects of EA persisted after the discontinuation of treatment.

In our trial, the leg pain NRS score was reduced by 49% compared with the baseline in the EA group at week 4; however, a greater increase in the response rate (69%) was reported in a trial comparing EA with TENS for sciatica during the treatment period. Another trial conducted in China demonstrated that the decrease in the mean value of the leg pain intensity NRS score in the EA group was 4.65 � 6.37 at week 4, which was higher than the value of 2.30 (1.86�2.75) obtained in our trial at the same time point. In a pilot trial comparing EA with physical therapy for symptomatic lumbar spinal stenosis (LSS), pain in the back and leg showed small improvements at 3 months. However, the ODI scores were different from the scores obtained in our study. No significant differences between the ODI scores of the two groups were observed at the 3-month follow-up time point in the study. The differences between the results of the two studies might be explained by the use of different acupoints, needling depth, manipulation methods, EA parameters, number and frequency, training and clinical experience level of the practitioners, missing data, and sample size.

Very few participants in either group took analgesics during the trial, and only anti-inflammatory drugs were used. This result might indicate that most of the participants believed that the analgesics would not alleviate pain and were concerned about adverse events. Most participants expected that EA or MFE would be beneficial and were aware that these techniques are relatively safe. According to the PGI, the participants perceived no difference between EA and MFE. Approximately 87.2% of the participants in the EA group reported that they were aided by EA at the 4th week, which was similar to the 83.5% of participants in the MFE group. The treatment acceptance assessment showed that none of the participants considered either treatment difficult to accept. Furthermore, 70.2% of the participants in the EA group reported that EA was easy or very easy to accept, similar to 72.5% of the participants in the MFE group. These results indicated that EA and MFE were both easy to accept and popular in China.

Leg pain is a typical symptom in sciatica patients, and the leg pain intensity NRS score reflects the improvement in this symptom in these patients. The leg pain NRS score may reasonably be used for the primary measurement of the therapeutic effect. Because studies have shown that most acupuncture therapy for sciatica lasts 1 to 4 weeks, we selected the change in the average leg pain intensity NRS score from baseline to the 4th week as the main measurement. In the previous literature, although primary outcome was generally measured at a certain time point, the average score reflected the average level of pain during the last week, which was thus more meaningful than other methods of measuring single time point due to recurrence of sciatica. The control group underwent MFE, which exerts its effect via the stimulation or activation of physiological events by applying energy, thereby producing therapeutic benefits that facilitate pain relief. Mechanisms leading to pain relief may be due to a variety of peripheral effects of control activity, on the spinal and spinal nervous system. The comparison between EA and MFE may reveal differences in response to needle penetration using the same electrostimulation. Because the stimulation parameters, particularly the frequency, are important factors that affect the outcome and because the effect of medium-frequency electrotherapy is better than the effect of low frequency electrotherapy, we used the same medium frequency and location in the study to ensure that the two groups were comparable.

Many studies have investigated the mechanism of EA. EA has been reported to relieve the symptoms of sciatica and increase the pain threshold in humans. Several previous studies showed that EA inhibited the primary afferent transmission of neuropathic pain and that deep EA stimulation improved the pathological changes and function of the injured sciatic nerve in rats. Other studies have suggested that descending inhibitory control, changes in nerve blood flow, or the inhibition of activity by nerve endings may be involved in the mechanism associated with the efficacy of EA. Long-lasting alleviation of pain has been suggested to be closely related to the muscle tension improvement provided by EA. A meta-analysis of patients with chronic pain showed that approximately 90% of the benefit of acupuncture was sustained at 12 months. The reason for the cumulative and sustained effects of acupuncture may be associated with the brain response and the cumulative duration of acupuncture stimulation.

This trial has several limitations. First, the participants and acupuncturists could not be blinded due to the significant difference between the two treatments. However, we followed rigorous quality control procedures in other aspects of the methodology. For example, a strict randomization and allocation concealment protocol was adopted. The outcome assessors and statisticians were blinded to the allocation. Second, some of the outcome measures of the trial were subjective. To address subjectivity, a short training session for the patients on the outcome reporting was held before they began the trial, and all subjective outcomes were based on the patient self-report forms. Third, we did not include a placebo control in the present preliminary study because several sham acupuncture randomized controlled trials (RCTs) have been performed to study acupuncture therapy in patients with sciatica. We considered that the use of a placebo did not provide sufficient sensitivity and may not have met ethical guidelines. Fourth, because we did not explore the effect of electroacupuncture EA on various degrees of pain severity, which degree of sciatica was most sensitive to EA was unclear. Subgroup analyses based on sciatica severity should be performed in a future multicenter, large-sample, randomized controlled study.

Conclusions: Electroacupuncture

This randomized controlled clinical trial demonstrated that the short-term and long-term effectiveness of electroacupuncture were superior to those of MFE in improving the symptoms of leg pain and dysfunction caused by chronic discogenic sciatica; moreover, the long-term effect of electroacupuncture was superior to that of MFE in improving low back pain. The results also suggested that the effect of electroacupuncture but not MFE lasted at least 28 weeks. No serious adverse events occurred in either group. Further studies are needed to examine the effectiveness of electroacupuncture relative to various physical therapy methods for patients with discogenic sciatica.

Acknowledgments

This trial was supported by the South Area of Guang’anmen Hospital science fund (Funding no. Y2015-07).

Conflicts of Interest

The authors have no conflicts of interest to declare.

In conclusion,�the effectiveness of electroacupuncture was superior to MFE towards improving the symptoms of discogenic sciatica. Although the research study concluded that electroacupuncture was superior to medium-frequency electrotherapy when treating for sciatica caused by degenerative disc disease, both types of treatments should still be used accordingly, depending on the patient’s condition and whether the specific treatment is best recommended by a healthcare professional. Electroacupuncture and medium-frequency electrotherapy are the most common types of treatment options for symptoms of sciatica associated with the deterioration of the spinal intervertebral discs. Information referenced from the National Center for Biotechnology Information (NCBI). The scope of our information is limited to chiropractic as well as to spinal injuries and conditions. To discuss the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .

Curated by Dr. Alex Jimenez

 

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Additional Topics: Sciatica

Sciatica is referred to as a collection of symptoms rather than a single type of injury or condition. The symptoms are characterized as radiating pain, numbness and tingling sensations from the sciatic nerve in the lower back, down the buttocks and thighs and through one or both legs and into the feet. Sciatica is commonly the result of irritation, inflammation or compression of the largest nerve in the human body, generally due to a herniated disc or bone spur.

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IMPORTANT TOPIC: EXTRA EXTRA: Treating Sciatica Pain

 

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Management of Sciatica: Nonsurgical & Surgical Therapies

Management of Sciatica: Nonsurgical & Surgical Therapies

Consider the following, sciatica is a medical term used to describe a collective group of symptoms resulting from the irritation or compression of the sciatic nerve, generally due to an injury or aggravated condition. Sciatica is commonly characterized by radiating pain along the sciatic nerve, which runs down one or both legs from the lower back. The following case vignette discusses Mr. Winston’s medical condition, a 50-year-old bus driver who reported experiencing chronic, lower back and leg pain associated with sciatica during a 4-week time period. Ramya Ramaswami, M.B., B.S., M.P.H., Zoher Ghogawala, M.D., and James N. Weinstein, D.O., provide a comprehensive analysis of the various treatment options available to treat sciatica, including undergoing lumbar disk surgery and receiving nonsurgical therapy.

 

On a personal note, as a practicing doctor of chiropractic, choosing the correct treatment care for any type of injury or condition can be a personal and difficult decision. If the circumstances are favorable, the patient may determine what is the best form of treatment for their type of medical issue. While nonsurgical therapies, such as chiropractic care, can often be utilized to improve symptoms of sciatica, more severe cases of sciatica may require surgical interventions to treat the source of the issue. In most cases, nonsurgical therapies should be considered first, before turning to surgical therapies for sciatica.

 

Case Vignette

 

A Man with Sciatica Who is Considering Lumbar Disk Surgery

 

Ramya Ramaswami, M.B., B.S., M.P.H.

 

Mr. Winston, a 50-year-old bus driver, presented to your office with a 4-week history of pain in his left leg and lower back. He described a combination of severe sharp and dull pain that originated in his left buttock and radiated to the dorsolateral aspect of his left thigh, as well as vague aching over the lower lumbar spine. On examination, passive raising of his left leg off the table to 45 degrees caused severe pain that simulated his main symptom, and the pain was so severe that you could not lift his leg further. There was no leg or foot weakness. His body-mass index (the weight in kilograms divided by the square of the height in meters) was 35, and he had mild chronic obstructive pulmonary disease as a result of smoking one pack of cigarettes every day for 22 years. Mr. Winston had taken a leave of absence from his work because of his symptoms. You prescribed 150 mg of pregabalin per day, which was gradually increased to 600 mg daily because the symptoms had not abated.

 

Now, 10 weeks after the initial onset of his symptoms, he returns for an evaluation. The medication has provided minimal alleviation of his sciatic pain. He has to return to work and is concerned about his ability to complete his duties at his job. He undergoes magnetic resonance imaging, which shows a herniated disk on the left side at the L4�L5 root. You discuss options for the next steps in managing his sciatica. He is uncertain about invasive procedures such as lumbar disk surgery but feels limited by his symptoms of pain.

 

Treatment Options

 

Which of the following would you recommend for Mr. Winston?

 

  1. Undergo lumbar disk surgery.
  2. Receive nonsurgical therapy.

 

To aid in your decision making, each of these approaches is defended in a short essay by an expert in the field. Given your knowledge of the patient and the points made by the experts, which option would you choose?

 

Option 1: Undergo Lumbar Disk Surgery
Option 2: Receive Nonsurgical Therapy

 

1. Undergo Lumbar Disk Surgery

 

Zoher Ghogawala, M.D.

 

Mr. Winston�s case represents a common scenario in the management of symptomatic lumbar disk herniation. In this particular case, the patient�s symptoms and the physical examination are consistent with nerve-root compression and inflammation directly from an L4�L5 herniated disk on his left side. The patient does not have weakness but has ongoing pain and has been unable to work for the past 10 weeks despite receiving pregabalin. Two questions emerge: first, does lumbar disk surgery (microdiskectomy) provide outcomes that are superior to those with continued nonoperative therapy in patients with more than 6 weeks of symptoms; and second, does lumbar microdiskectomy improve the likelihood of return to work in patients with these symptoms?

 

The highest quality data on the topic come from the Spine Patient Outcomes Research Trial (SPORT). The results of the randomized, controlled trial are difficult to interpret because adherence to the assigned treatment strategy was suboptimal. Only half the patients who were randomly assigned to the surgery group actually underwent surgery within 3 months after enrollment, and 30% of the patients assigned to nonoperative treatment chose to cross over to the surgical group. In this study, the patients who underwent surgery had greater improvements in validated patient-reported outcomes. The treatment effect of microdiskectomy was superior to that of nonoperative treatment at 3 months, 1 year, and 2 years. Moreover, in an as-treated analysis, the outcomes among patients who underwent surgery were superior to those among patients who received nonoperative therapy. Overall, the results of SPORT support the use of microdiskectomy in this case.

 

Results of clinical trials are based on a comparison of treatment options in study populations and may or may not apply to individual patients. SPORT did not specify what type of nonoperative therapy was to be used. Physical therapy was used in 73% of the patients, epidural injections in 50%, and medical therapies (e.g., nonsteroidal antiinflammatory drugs) in more than 50%. In the case of Mr. Winston, pregabalin has been tried, but physical therapy and epidural glucocorticoid injections have not been attempted. Despite widespread use of physical therapy for the treatment of lumbar disk herniation, the evidence supporting its effectiveness is inconclusive, according to published guidelines of the North American Spine Society. On the other hand, there is evidence that transforaminal epidural glucocorticoid injection provides short-term relief (30 days) in patients with nerve-root symptoms directly related to a herniated disk. Overall, there is evidence, from SPORT and from a randomized trial from the Netherlands published in the Journal, that early surgery between 6 and 12 weeks after the onset of symptoms provides greater alleviation of leg pain and better overall pain relief than prolonged conservative therapy.

 

The ability to return to work has not been formally studied in comparisons of operative with nonoperative treatments for lumbar disk herniation. Registry data from the NeuroPoint-SD study showed that more than 80% of the patients who were working before disk herniation returned to work after surgery. The ability to return to work may be dependent on the type of vocation, since patients who are manual laborers may need more time to recover to reduce the risk of reherniation.

 

It is well recognized that many patients who have a symptomatic lumbar disk herniation will have improvement spontaneously over several months. Surgery can alleviate symptoms more quickly by immediately removing the offending disk herniation from the affected nerve root. The risk�benefit equation will vary among individual patients. In the case of Mr. Winston, obesity and mild pulmonary disease might increase the risk of complications from surgery, although in SPORT, 95% of surgical patients did not have any operative or postoperative complication. For Mr. Winston, a patient with pain that has persisted for more than 6 weeks, microdiskectomy is a rational option that is supported by high-quality evidence.

 

2. Receive Nonsurgical Therapy

 

James N. Weinstein, D.O.

 

This case involves a common presentation of low back pain radiating to the buttock and posterolateral thigh that might represent either referred mechanical pain or radiculopathy. Classic radiculopathy resulting from compression of a lower lumbar nerve root (L4, L5, or S1) results in pain that radiates distal to the knee and is often accompanied by weakness or numbness in the respective myotome or dermatome. In this case, the pain is proximal to the knee and is not associated with weakness or numbness. In SPORT, surgery resulted in faster recovery and a greater degree of improvement than nonoperative treatment in patients with pain that radiated distal to the knee and was accompanied by neurologic signs or symptoms. However, since Mr. Winston would not have met the inclusion criteria for SPORT, the results of diskectomy in this case would be somewhat unpredictable. He does not have radiculopathy that radiates below the knee, and he does not have weakness or numbness; nonoperative treatment should be exhausted before any consideration of a surgical procedure that in most cases has not been shown to be effective in patients with this type of presentation. In this issue of the Journal, Mathieson and colleagues report the results of a randomized, controlled trial that showed that pregabalin did not significantly alleviate pain related to sciatica. Mr. Winston has been treated only with pregabalin; therefore, other conservative options should be explored.

 

Saal and Saal reported that more than 80% of patients with radiculopathy associated with a lumbar disk herniation had improvement in a matter of months with exercise-based physical therapy. In the nonoperative SPORT cohort, patients had significant improvement from baseline, and approximately 60% of those with classic radiculopathy who initially received nonoperative treatment avoided surgery. Mr. Winston has had minimal treatment and has had symptoms for only 10 weeks. He should undergo a course of exercise-based physical therapy and a trial of a nonsteroidal antiinflammatory medication and may consider a lumbar epidural glucocorticoid injection. Although there is little evidence of the effectiveness of these nonoperative options alone, the combination of these treatments and the benign natural history of the patient�s condition could result in alleviation or resolution of symptoms. If these interventions � and time � do not resolve his symptoms, surgery could be considered as a final option, but it may not have long-term effectiveness and could in and of itself cause the possibility of more harm than good. Mr. Winston has risk factors, such as obesity and a history of smoking, that have been shown to contribute to poor surgical outcomes of certain spinal procedures.

 

Mr. Winston has symptoms of back pain that interfere with his quality of life. He would need to understand, through shared decision making, that a nonsurgical approach is likely to be more effective than surgery over time.

 

Information referenced from the National Center for Biotechnology Information (NCBI) and the New England Journal of Medicine (NEJM). The scope of our information is limited to chiropractic as well as to spinal injuries and conditions. To discuss the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .

 

Cited by Dr. Alex Jimenez

 

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Additional Topics: Wellness

 

Overall health and wellness are essential towards maintaining the proper mental and physical balance in the body. From eating a balanced nutrition as well as exercising and participating in physical activities, to sleeping a healthy amount of time on a regular basis, following the best health and wellness tips can ultimately help maintain overall well-being. Eating plenty of fruits and vegetables can go a long way towards helping people become healthy.

 

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IMPORTANT TOPIC: EXTRA EXTRA: Treating Sciatica Pain

 

 

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References

 

  • 1. Weinstein JN, Tosteson TD, Lurie JD, et al. Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial. JAMA 2006;296:24412450

  • 2. Weinstein JN, Lurie JD, Tosteson TD, et al. Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort. JAMA 2006;296:24512459

  • 3. Kreiner DS, Hwang SW, Easa JE, et al. An evidence-based clinical guideline for the diagnosis and treatment of lumbar disc herniation with radiculopathy. Spine J 2014;14:180191

  • 4. Ghahreman A, Ferch R, Bogduk N. The efficacy of transforaminal injection of steroids for the treatment of lumbar radicular pain. Pain Med 2010;11:11491168

  • 5. Peul WC, van Houwelingen HC, van den Hout WB, et al. Surgery versus prolonged conservative treatment for sciatica. N Engl J Med 2007;356:22452256

  • 6. Ghogawala Z, Shaffrey CI, Asher AL, et al. The efficacy of lumbar discectomy and single-level fusion for spondylolisthesis: results from the NeuroPoint-SD registry: clinical article. J Neurosurg Spine 2013;19:555563

  • 7. Deyo RA, Weinstein JN. Low back pain. N Engl J Med 2001;344:363370

  • 8. Lurie JD, Tosteson TD, Tosteson AN, et al. Surgical versus nonoperative treatment for lumbar disc herniation: eight-year results for the spine patient outcomes research trial. Spine (Phila Pa 1976) 2014;39:316

  • 9. Mathieson S, Maher CG, McLachlan AJ, et al. Trial of pregabalin for acute and chronic sciatica. N Engl J Med 2017;376:11111120

  • 10. Saal JA, Saal JS. Nonoperative treatment of herniated lumbar intervertebral disc with radiculopathy: an outcome study. Spine (Phila Pa 1976) 1989;14:431437

  • 11. Pinto RZ, Maher CG, Ferreira ML, et al. Drugs for relief of pain in patients with sciatica: systematic review and meta-analysis. BMJ 2012;344:e497e497

  • 12. Pearson A, Lurie J, Tosteson T, et al. Who should have surgery for an intervertebral disc herniation? Comparative effectiveness evidence from the Spine Patient Outcomes Research Trial. Spine 2012;37:140149

  • 13. Weeks WB, Weinstein JN. Patient-reported data can help people make better health care choices. Harvard Business Review. September 21, 2015

 

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Suffer From Sciatica: Chiropractic Care Reduces Pain, Promotes Healing

Suffer From Sciatica: Chiropractic Care Reduces Pain, Promotes Healing

Suffer Sciatica: Are you experiencing pain along one side of your body from your lower back down through your hip and the back of your leg? If so, you could be suffering from a condition called sciatica.

According to the Mayo Clinic, sciatica can best be described as “most commonly occurring when a herniated disk or a bone spur on the spine compresses part of the nerve. This causes inflammation, pain and often some numbness in the affected leg.”

A variety of issues weigh in on an individual’s likelihood of ending up with sciatica. Most of them deal with increased pressure on the spine.

Suffer Sciatica: Causes

Obesity: carrying too much weight is instrumental in bringing on a number of health related issues. Extra pounds overload the spine, causing damage that results in sciatica.

Improper Lifting: Individuals who frequently twist the bodies and lift heavy loads are more likely to suffer from sciatica. Certain jobs that require these movements are a key cause of the condition.

Sedentary Lifestyle. A person’s job does not have to involve lifting to be responsible for this condition. Sitting for extended periods without stretching or standing puts excess pressure on the spine and can cause sciatica.

Too Many Birthdays. Getting older can affect all of our body’s joints and bones in a negative manner, especially if we never committed to an exercise routing. An individual’s back often deteriorates with age, causing bone spurs and herniated disks that sometimes result in sciatica.

Treatment options for sciatica are varied, and the choice depends on the severity of the condition.

Pain Medication: A common and easy way to treat sciatica is with drug therapy. Anti-inflammatory drugs are frequently used to reduce�the inflammation around the nerve, which is a big contributor of the pain. Over-the-counter pain medicines, as well as codeine, may also help with pain management.

suffer medical diagnosis of a pinched nerve

Acupuncture. Alternative therapies like acupuncture have shown positive results in the treatment of sciatica. If a drug-free treatment option appeals to you, find an experienced acupuncturist in your area and talk to them about treatment options.

Strengthening Exercises. A consistent exercise program strengthens your muscles and helps the body function effectively. Ask your doctor which exercises assist the body with bouncing back from sciatica.

Supplements. Supplying the body with vital vitamins and minerals assists in overall health in general, including improvement from sciatica. Daily doses of supplements such as calcium, magnesium, St. John’s Wort, and Vitamin B12 have shown to treat sciatica effectively.

Chiropractic Care. Chiropractors understand all things spine-related, and work with the body as a whole to help it heal itself. Chiropractic treatment for sciatica works to align the spine and reduce the stress to the lower back. Treatment helps alleviate the underlying causes of the condition, and shows positive results in a short amount of time.

Cortisone Injections. Most of the time, sciatica can be treated by the less invasive measures mentioned above. However, severe bouts of sciatica may require a shot of cortisone directly into the inflamed area. Individuals generally choose this option when other treatments have garnered no relief.

Dealing with sciatica is painful and irritating, as the condition often sidelines the sufferer from daily activities. By knowing the treatment options that are effective in combating both the underlying causes and the pain of sciatica, sufferers can begin a regimen that will help them get back on their feet, pain-free in the shortest period of time possible and no longer have to suffer.

If you are suffering from sciatica and would like to talk to an experienced chiropractor about how to treat the condition, contact us today.

Sciatica

This article is copyrighted by Blogging Chiros LLC for its Doctor of Chiropractic members and may not be copied or duplicated in any manner including printed or electronic media, regardless of whether for a fee or gratis without the prior written permission of Blogging Chiros, LLC.

Relieve Piriformis Syndrome With Chiropractic Care

Relieve Piriformis Syndrome With Chiropractic Care

Relieve: A small muscle located deep in the buttocks, the piriformis muscle performs the essential function of rotating the leg outwards. Piriformis Syndrome is a painful condition that occurs when the piriformis muscle is tight and intrudes upon the sciatic nerve in the buttocks. Causing pain and tenderness and sometimes numbness in the buttocks, piriformis syndrome pain may also radiate down the sufferer’s leg, and in some cases, even into the calf.

There are two commonly identifiable potential causes for piriformis syndrome. One is sitting for prolonged periods of time, which can cause tightening of the muscle. The second cause is an injury to the buttocks, either by a fall, an accident, or a sports injury. Trauma causes the piriformis muscle to swell and irritate the sciatic nerve.

Spasms can also cause piriformis syndrome, however, the underlying cause of the spasms frequently remains unknown.

Unfortunately, once an individual has suffered from piriformis syndrome, the condition can recur periodically, usually brought on by too much exercise or sitting for a long time without stretching.

Whatever the initial cause, piriformis syndrome treatment options are vital in relieving the painful symptoms and healing the condition.

Relieve:

These Four Treatment Options Are Frequently Used To Treat Piriformis Syndrome.

relieve man with piriformis syndrome in pain grabbing back

Medication. Over-the-counter or prescribed pain medicines, anti-inflammatory drugs, or muscle relaxers frequently serve to reduce the pain from piriformis syndrome. A doctor may also inject medicine directly into the piriformis muscle to improve the condition.

Heat. A common way to relax tight muscles is to apply heat. Piriformis syndrome sufferers may find relief from painful symptoms by periodically applying heat directly to the tender area.

Heat therapy may relieve the tightness of the muscle and promote healing of the entire area. However, it’s important to avoid treating the muscle with heat if there is a chance the muscle may be torn.

Exercise. The overall cause of the condition is a tight piriformis muscle, so it stands to reason a proper exercise regimen will loosen the muscle and alleviate the symptoms associated with piriformis syndrome. A doctor can prescribe the correct exercises to stretch and subsequently strengthen the muscles and the body’s other muscles. A strong body will reduce the chances of the issue recurring down the road.

Hands on therapy. Used with other types of treatment or on their own, these types of therapies are popular because of their effectiveness, as well as the fact they are drug-free ways to gain relief from the pain. Massage is a commonly used therapy for piriformis syndrome, as it helps increase blood flow to the area. The massage therapist can manipulate the area to relieve the tightness of the muscle.

Another hands on therapy that produces positive results is chiropractic care.

Chiropractors view the body in its entirety, and will often treat other parts of the body, such as a foot or leg, in order to improve the condition of the piriformis muscle. They may also utilize a regimen of pelvic and spinal adjustments along with joint manipulation and stretching to loosen up the muscle and help heal the afflicted area.

As stated earlier, once the condition has been controlled and the area has healed, it’s vital to take precautions to avoid re-aggravating the area. Proper stretching before exercise, periodic breaks when sitting, and maintaining spinal and pelvic alignment will increase an individual’s chances of living free of the pain of piriformis syndrome in the future.

Treating Sciatica

If you have a question about how chiropractic care can help with the symptoms of piriformis syndrome, or other health conditions, contact us today.

This article is copyrighted by Blogging Chiros LLC for its Doctor of Chiropractic members and may not be copied or duplicated in any manner including printed or electronic media, regardless of whether for a fee or gratis without the prior written permission of Blogging Chiros, LLC.