Folate, and its synthetic form folic acid, is a water-soluble B vitamin that plays a fundamental role in a variety of functions in the human body. Folate is essential for cell division and homeostasis because it acts as a coenzyme in many biological pathways, including amino acid metabolism, methionine production, and DNA methylation. Folate metabolism happens together with the methionine cycle and the choline pathway. Most folate coenzymes are found in the liver.
Folate is also used as a coenzyme to convert methionine into homocysteine. Vitamin B6 and B12, together with folate, are also essential for DNA synthesis. Proper dietary intake of folate is fundamental for normal cell growth and DNA repair. Folate or vitamin B12 deficiency can ultimately cause a variety of health issues, including anemia. Oral supplementation may be necessary. In the following article, we will discuss folate metabolism and foods that are high in folate.
Contents
Folate Metabolism Overview
Several of the most important functions of folate metabolism are methylation and S-adenosylmethionine (SAM) production, one of the most essential methyl donors in the cell. In the following diagram, we will explain folate metabolism.�
Figure 1: One carbon metabolism. ATP: adenosyl triphosphate, B6: vitamin B6, B12: vitamin B12, BHMT: betaine homocysteine methyltransferase, CBS: cystathionine-?-synthase, DHF: dihydrofolate, DMG: dimethylglycine, dTMP: deoxythymidine monophosphate, dUMP: deoxyuridine monophosphate, Gly: glycine, Hcy: homocysteine, MAT: methionine adenosyltransferase, Met: methionine, MCM: L-methylmalonyl CoA mutase, MM-CoA: L-methylmalonyl CoA, MMA: methylmalonic acid, MS: methionine synthase, MTHFR: 5,10-methyltetrahydrofolate reductase, SAH: S-adenosyl homocysteine, SAHH: S-adenosyl homocysteine hydrolase, SAM: S-adenosyl methionine, Ser: serine, SHMT, serine hydroxymethyltransferase, THF: tetrahydrofolate, TS: thymidylate synthase. Adapted from: Hypo- and hypervitaminosis of B and D vitamins � Diagnosis and clinical consequences. Herrmann W. et al. 2013. Uni-Med Verlag AG.
Dihydrofolate reductase (DHFR) is a component that converts folate to dihydrofolate (DHF) and DHF to the active form, THF. Folate metabolism consists of three cycles. One cycle starts with a component known as 10-formylTHF which is associated with purine production and two cycles utilize 5, 10-methyleneTHF in deoxythymidine monophosphate (dTMP) and methionine production. 5-MethylTHF is one of the most predominant forms of folate found in the human body.
After cellular uptake, 5-methylTHF is converted into THF through the use of vitamin B12 in methionine synthase (MS). The methionine cycle is a fundamental pathway in SAM production. As previously mentioned above, B vitamin deficiencies, including folate, vitamin B6, and B12, as well as genetic birth defects can ultimately cause a variety of health issues. 5,10-MethyleneTHF is finally converted to 5-methylTHF by 5,10-methylenetetrahydrofolate reductase (MTHFR).
Several of the most important functions of folate metabolism are methylation and S-adenosylmethionine (SAM) production, one of the most essential methyl donors in the cell. In the following diagram, we will simplify folate metabolism.�
15 Foods That Are High in Folate
Folate, and its synthetic form folic acid, is a water-soluble B vitamin that plays a fundamental role in a variety of functions in the human body. It�supports cell division and promotes fetal growth and development to reduce the risk of genetic birth defects. Folate is naturally found in many different types of foods. Doctors recommend 400 mcg of folate every day for adults to prevent deficiency. Here are 15 healthy foods that are high in folate or folic acid, including:
avocado
bananas
citrus fruits
papaya
beets
leafy greens
asparagus
Brussels sprouts
broccoli
nuts and seeds
legumes
eggs
beef liver
wheat germ
fortified grains
In conclusion, folate, and its synthetic form folic acid, is an important micronutrient that can be naturally found in many different types of foods. Eating many different types of healthy foods, including fruits, vegetables, nuts, and seeds, as well as fortified foods, is an easy way to increase your folate intake. These foods are not only high in folate but these are also high in other essential nutrients that can ultimately improve other aspects of your overall health.
For information regarding the nutritional role of folate, please review the following article:
Folate or folic acid is a water-soluble B vitamin that plays a fundamental role in a variety of functions in the human body, including cell division and homeostasis. Folate also helps with amino acid metabolism, methionine production, and DNA methylation.�Folate or vitamin B12 deficiency can ultimately cause a variety of health issues. Oral supplementation may be necessary. In the diagrams above, we explain the process of folate metabolism.�Folate is naturally found in many different types of foods, including avocado, citrus fruits, leafy greens, broccoli, nuts and seeds, legumes, eggs, and fortified grains.�Eating many different types of healthy foods is an easy way to increase your folate intake. These foods are not only high in folate but these are also high in other essential nutrients that can ultimately improve other aspects of your overall health.�- Dr. Alex Jimenez D.C., C.C.S.T. Insights
Berry Bliss Smoothie
Servings: 1 Cook time: 5-10 minutes
� 1/2 cup blueberries (fresh or frozen, preferably wild)
� 1 medium carrot, roughly chopped
� 1 tablespoon ground flaxseed or chia seed
� 1 tablespoons almonds
� Water (to desired consistency)
� Ice cubes (optional, may omit if using frozen blueberries)
Blend all ingredients in a high-speed blender until smooth and creamy. Best served immediately.
Almonds have twice as much calcium as milk
Gram for gram this is absolutely true! According to McCance and Widdowson’s Composition of Foods (the official guide to the nutrients in food used in the UK), about 100g of almonds have 240mg of bone-building calcium while semi-skimmed (2%) milk has 120mg per 100g (3.5oz). With that being said, however, we tend to drink milk in bigger quantities than we eat almonds (and the calcium from milk is easily absorbed), so the dairy option may be a better source day-to-day.
The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require an additional explanation as to how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900. The provider(s) Licensed in Texas*& New Mexico*�
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
Almas, Saneea. �Folic Acid: An Overview of Metabolism, Dosages, and Benefits of Optimal Periconception Supplementation: InfantRisk Center.� Infant Risk Center, Texas Tech University Health Sciences Center, www.infantrisk.com/content/folic-acid-overview-metabolism-dosages-and-benefits-optimal-periconception-supplementation.
Link, Rachael. �15 Healthy Foods That Are High in Folate (Folic Acid).� Healthline, Healthline Media, 27 Feb. 2020, www.healthline.com/nutrition/foods-high-in-folate-folic-acid.
Shuhei, Ebara. �Nutritional Role of Folate.� Congenital Anomalies, U.S. National Library of Medicine, 11 June 2017, pubmed.ncbi.nlm.nih.gov/28603928/?from_term=folate%2Bmetabolism&from_pos=3.
MSN Lifestyle Staff. �Coffee Is a Fruit and Other Unbelievably True Food Facts.� MSN Lifestyle, MSN Lifestyle Media, 4 June 2020, www.msn.com/en-us/foodanddrink/did-you-know/coffee-is-a-fruit-and-other-unbelievably-true-food-facts/ss-BB152Q5q?li=BBnb7Kz&ocid=mailsignout#image=5.
An overview of chiropractic treatment for lower lumbar back pain, how it works, how safe it is, and how often treatment is necessary. Along with the principles of chiropractic for the relief of lower/lumbar back pain, whether acute or chronic. Seeing a doctor ofchiropractic/DC, a chiropractor�or a chiropractic physician can be highly beneficial towards effectively treating low back pain. �
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Contents
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Practice
Chiropractic medicine utilizes a variety of treatments/therapies that are designed to manipulate/adjust the:
Spine
Joints
Tissues
These treatments focus on the entire body to relieve pain and improve functional ability. This is referred to as spinal manipulative therapy or SMT, but there are many other treatment methods and techniques.
Every chiropractor has a personal treatment approach based on the patient’s condition/s, medical history, and personalized treatment plan. A chiropractor will begin traditionally starting off with soft, natural, less-invasive treatments. If these do not generate positive results they will move on to more aggressive techniques.
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Consent Form
At every stage of the chiropractic process, there is a strict emphasis maintained on proactively discussingwith the patient exactly what is taking place and what is going to happen. A chiropractor makes sure that the patient understands everything that occurs during:
Diagnosis
Examination
Procedure/s
This is all done in order to educate the patient and receive direct permission to start the treatment. The emphasis on informed consent is essential. This is because some chiropractic techniques could carry material risk. This means that a certain technique or particular procedure could possibly cause injury.
A chiropractor also informs the patient of the possible risks of not being treated. It is not meant to scare a patient. It is to eliminate any misunderstandings and make sure that the patient has full control over their body, so they can make an informed decision, as to which way they want to go. �
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Examination
A chiropractor will thoroughly examine a patient before making any sort of diagnosis or treatment plan. The assessment can include:
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Medical history
The characteristics of the pain, any red flag symptoms that require further diagnostic testing will be conducted to remove any potentially serious medical issues that can be associated with neck or lower lumbar back pain-like:
Neurological disorders
Fractures
Infections
Tumors
There can be many reasons as to why low lumbar back pain happens. A chiropractor will investigate and develop a personally customized treatment plan. Next, a physical exam will be performed. This includes an orthopedic and neurological exam. These will test the:
Reflexes
Sensory nerves
Joints
Muscles
Other areas of the body
�
Advanced Diagnostic Testing
Imaging and laboratory tests are not always used for non-specificlower lumbar back pain, but they could be necessary if there are signs/symptoms of an underlying condition.
�
Severity/Duration of Condition
Chiropractic medicine looks at the symptoms and conditions of an injury or ailment and classifies them on how severe they are, and how long they last. Symptoms can be divided into degrees of severity: They are:
Mild
Moderate
Severe
For the duration period, pain and other symptoms are referred to as:
Acute pain – lasts for less than 6 weeks
Subacute – lasts between 6 and 12 weeks
Chronic – lasts for at least 12 weeks
Flare-ups – the same symptoms happen irregularly or from an exacerbation of the original injury
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Treatment Trial
If an individual is dealing with acute or subacute lower lumbar back pain, then a chiropractic trial could be an option. This could be two to three weekly sessions over the course of two to four weeks adding up to twelve total sessions. This can be a sufficient treatment to completely alleviate the pain. However, when the pain does not go away then additional treatments could be necessary, especially if an individual has other issues/conditions.
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Measured Outcomes
Outcome measurements are a valuable tool because they help determine whether or not the treatment is producing significant results. Some outcome measurements of treatments include:
Numeric Pain Scale for patients to rate the pain
Pain diagram so patients can describe the location and character of the pain
Increases and decreases in normal daily practices, like work, exercise, and sleep
Testing functions
Lifting ability
Strength
Flexibility
Endurance
For some low lumbar back pain could last and go over the 12-week mark making it a chronic pain condition. A chiropractor will look for signs/symptoms to see if there is a risk of developing chronic pain. �
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Chiropractic How Often
When the pain is acute lower lumbar back pain, a standard treatment plan can be six to ten sessions over the course of two to four weeks. These treatments emphasize the passive non-exercise approach of manual therapy for relieving pain and improving function.
If the non-exercise method doesn’t deliver positive results then a more active exercise-based treatment can be utilized to increase function and return an individual back to normal life.
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Back Pain That Doesn’t Go Away
Often acute symptoms are resolved within the first 4-weeks. But it is possible that the pain can become chronic, meaning that it lasts longer than 12 weeks. Some individuals can hit a plateau during the recovery process.
This is referred to as MTB or that the patient has met the therapeutic benefits. A chiropractor will want to see if pausing/stopping chiropractic treatment will have a residual effect, exacerbate the pain, or reduce function and activity.
Example: If mild to severe chronic lower lumbar back pain has worsened, a patient could need one to six more visits with each pain episode. And this would be two to three weekly treatments for two to four weeks. However, patients rarely need continuing or ongoing care of one to four visits per month.
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Re-Evaluation
Chiropractors will not continue treatment/s if they are not helping the patient. Therefore, every 2 to 4 weeks there is a re-evaluation of the patient to see if the treatment is still having a positive and beneficial effect. Here are some of the criteria for continuing treatment:
Individual still responds positively to the treatment
The individual has met the therapeutic benefits and worsens when they are not treated
Proof shows that self-care alone will not be sufficient to maintain the therapeutic benefits
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Continuing Treatment
Living with chronic lower lumbar back pain can be a challenge, but chiropractors want to emphasize to individuals that self-care is an essential component for pain management. This includes physical rehabilitation combined with range-of-motion exercises. A chiropractic physician may encourage a variety of treatment options, like:
Chiropractic treatment and the benefits are different for everybody. This is why it is important to communicate with your chiropractor every step of the way and to be open-minded about the different treatment options they offer.
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Lower Back Pain Chiropractic Treatment
Dr. Alex Jimenez�s Blog Post Disclaimer
The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.*
Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require an additional explanation as to how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900. The provider(s) Licensed in Texas*& New Mexico*�
Our diet can significantly affect inflammation in our bodies. Several foods can increase inflammation while other foods can reduce inflammation. According to healthcare professionals, a diet that is high in sugar may be associated with chronic inflammation. A systematic review in 2018 demonstrated that eating excess sugar can ultimately cause inflammation and a variety of other health issues, such as diabetes. Another 2014 research study showed that people who decreased their consumption of sugary or sweetened drinks had reduced inflammation. These research findings support the theory that eating excess sugar can cause chronic inflammation and various other diseases, including diabetes.
Contents
How Sugar Can Cause Inflammation
Healthcare professionals have tried to understand how eating excess sugar can cause chronic inflammation. Sugar triggers the production of free fatty acids in the liver. When the human body digests these free fatty acids, the resulting compounds can trigger inflammation. Different types of sugar may also cause more inflammation. By way of instance, one research study found that fructose can cause more inflammation than glucose. However, a systematic review found that fructose didn’t cause more inflammation than glucose. Therefore, further research studies are still required to determine which types of sugar may cause more inflammation. Symptoms associated with chronic inflammation can include:
pain and fatigue
sleeping problems or insomnia
anxiety, depression, and other mood disorders
digestive problems like acid reflux, constipation, and/or diarrhea
weight gain or obesity
constant infections
People with chronic inflammation may also have an increased risk of developing a variety of other health issues, including diabetes and dementia. Chronic inflammation in older adults may also be associated with an increased risk of death.
Health Issues Caused by Chronic Inflammation
Observational research studies in humans have associated diets with high added sugar and refined carbohydrates to the increased risk of developing a variety of health issues, including diabetes, IBD, liver disease, dementia, and arthritis.
Diabetes
Research studies showed a connection between the increased consumption of added sugar and type 2 diabetes. A large analysis that included over 38,000 participants found that simply consuming one serving of sweetened drinks or beverages on a regular basis was associated with an 18 percent increased risk of developing type 2 diabetes. Another research study found that increasing the consumption of high-fructose corn syrup was also associated with diabetes.
Other Diseases
Increased consumption of added sugar and refined carbohydrates has also been associated with the development of other diseases, such as arthritis, inflammatory bowel disease, liver disease, and dementia. Furthermore, excess fructose consumption has been associated with non-alcoholic fatty liver disease. Healthcare professionals believe this may be due to a combination of ongoing low-grade inflammation, increased gut permeability, and bacterial overgrowth in the gut.
Other Foods That Can Cause Inflammation
sugary foods like pastries, desserts, and chocolate
saturated fats from processed meats and dairy products
trans fats found in fast, fried, foods
vegetable and seed oils
refined carbohydrates
excessive alcohol
MSG in prepared Asian foods and deli meats
For information regarding how excess sugar can cause chronic inflammation and various other health issues like diabetes, please review this article:
Diet can affect inflammation in our bodies. Several foods can increase inflammation while other foods can reduce inflammation. A diet that is high in sugar may be associated with inflammation. Numerous research studies have demonstrated that eating excess sugar can ultimately cause chronic inflammation and various other diseases, including diabetes. Because sugar triggers the production of free fatty acids in the liver, it can also trigger inflammation. Excess sugar can cause chronic inflammation. Different types of sugar may also cause different amounts of inflammation. There are many symptoms associated with chronic inflammation, including pain, fatigue, obesity, anxiety, and depression, among others. Inflammation can lead to a variety of health issues, such as diabetes and arthritis. Although excess sugar is associated with chronic inflammation, other foods like saturated fats and refined carbohydrates can also cause health issues. In the following article, we discuss how sugar can cause inflammation and a variety of other health issues, such as diabetes, in the human body. – Dr. Alex Jimenez D.C., C.C.S.T. Insights
Sea Green Smoothie
Servings: 1Cook time: 5-10 minutes
� 1/2 cup cantaloupe, cubed
� 1/2 banana
� 1 handful of kale or spinach
� 1 handful of Swiss chard
� 1/4 avocado
� 2 teaspoons spirulina powder
� 1 cup of water
� 3 or more ice cubes
Blend all ingredients in a high-speed blender until completely smooth and enjoy!
Leafy Greens Hold the Key to Gut Health
A unique type of sugar found in leafy greens can help feed our beneficial gut bacteria. Sulfoquinovose (SQ) is the only known sugar molecule to be made up of sulfur, an extremely essential mineral in the human body. The human body uses sulfur to produce enzymes, proteins, and a variety of hormones as well as antibodies for our cells. A fast and easy way to get leafy greens into your diet is to toss a couple of handfuls of them into a delicious smoothie!
The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require an additional explanation as to how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900. The provider(s) Licensed in Texas*& New Mexico*�
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
Spritzler, Franziska. �6 Foods That Cause Inflammation.� Healthline, Healthline Media, 12 Nov. 2019, www.healthline.com/nutrition/6-foods-that-cause-inflammation#1.
Caporuscio, Jessica. �Does Sugar Cause Inflammation? What the Research Says.� Medical News Today, MediLexicon International, 19 Sept. 2019, www.medicalnewstoday.com/articles/326386.
Brown, Mary Jane. �Does Sugar Cause Inflammation in the Body?� Healthline, Healthline Media, 12 Nov. 2017, www.healthline.com/nutrition/sugar-and-inflammation.
Spinal stimulation is a treatment option that could help bring relief from pain and improve the quality of life for individuals dealing with chronic pain, like low back, and leg pain. Spinal stimulation can help reduce and manage chronic pain that does not alleviate or reduce with physical therapy, pain medications, injections, and other non-surgical treatments/therapies. �
It is a form of neuromodulation that works by blocking pain signals that the nerves send out from reaching the brain. A spinal stimulator is a tiny device that is implanted underneath the skin. The device delivers a very low electrical impulse that masks/changes pain signals before they reach the brain.
Contents
�
A Spinal Stimulation System
�
Neurostimulator:
This is the entire device that is implanted and sends out electrical impulses through a lead wire to the nerves in the spine.
Lead:
The thin wire that delivers the electrical impulses from the neurostimulator.
Remote control:
This turns on/off the stimulator and increases or decreases the amount of stimulation.
Charger:
Stimulators are rechargeable and normally require recharging about one hour every two weeks.
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Spinal Stimulator Types:
�
Traditional stimulators
These produce a gentle ringing/tingling sensation that masks the pain.
Burst stimulators
These send out random interval bursts of electrical impulses designed to copy the way the body sends out nerve impulses.
High-frequency stimulators
These reduce pain without generating tingling sensations. �
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Types of Pain Spinal Stimulation Treats
Spinal stimulation is approved by the U.S. FDA to treat chronic back and leg pain, including pain that doesn’t go away after back surgery known as failed back surgery syndrome. Chronic neuropathic back and leg pain are the most common types that stimulation treats. This means back or leg pain caused by nerve damage from:
Auto accident
Injury – personal, sports, work
Disease
Acute pain is like stepping on a sharp piece of glass, where the pain serves as protection letting you know something is wrong and not to continue. Whereas chronic neuropathic pain lasts for 3 months or more and does not help protect the body. �
�
Spinal stimulation is also used to treat complex regional pain syndrome or CRPS. This is a rare condition that affects the arms/hands or legs/feet and is believed to be caused by damage or malfunction of the nervous system. It is also used in treating peripheral neuropathic pain. This is damage to the nerves outside of the spinal cord often in the hands/feet that is caused by an:
Infection
Trauma
Surgery
Diabetes
Other unknown causes
�
Appropriate Treatment
Spinal cord stimulation should not be used in patients that are pregnant, unable to operate the stimulation system, went through a failed trial of spinal stimulation, and are at risk for surgical complications. The decision to use spinal stimulation is based on an individual’s needs and risks. Talk to a doctor, spine specialist, chiropractor to see if spinal stimulation could be an option.
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Benefits and Risks
The effects of stimulation are different for everyone. Therefore, it is important to understand that spinal stimulation can help reduce pain, but not completely eliminate it. �
�
The Benefits of Spinal Cord Stimulation
In addition to reducing pain, other benefits of spinal stimulation include:
Better sleep
Improved body function
Increased activity
Improved mobility
Reduced opioid medication/s use
Less need for other types of pain meds
Reduced dependence on braces/bracing
�
Risks
During the implantation, there is a risk for:
Bleeding
Infection
Pain at the site of incision
Nerve damage
Rarely paralysis
� For some individuals, scar tissue can build up over the electrode, which can block the stimulator’s electrical impulse. The lead wire could move or shift out of position. This could lead to impulses being sent to the wrong location. The device itself could shift under the skin causing pain, making it hard to re-charge or communicate with the remote.
There is a risk that the lead wire could detach or break off causing a malfunction and require a replacement. Also, individuals could respond well to the stimulation at first, but later on, they develop a tolerance, and so the therapy no longer has the same impact and the pain could get worse because the nerves stop responding.
�
Take Precautions
Discuss with a doctor, spine specialist, or chiropractor what you can and can’t do after the stimulator is implanted and activated. Here are a few precautions:
Do not drive or operate heavy equipment when the stimulator is active.
Stimulation systems could set off metal detectors, which could require manual screening.
MRIs, electrocautery, diathermy, defibrillators, and cardiac pacemakers could have a negative interaction with certain types of stimulators. This could result in injury or damage to the spinal stimulator. Talk to your doctor to determine if a spinal stimulator is a treatment option that will work for you.
�
Weight Loss Techniques – Push Fitness Center
Dr. Alex Jimenez�s Blog Post Disclaimer
The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.*
Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require an additional explanation as to how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at�915-850-0900. The provider(s) Licensed in Texas& New Mexico
The MTHFR or methylenetetrahydrofolate reductase gene is well-known due to a genetic mutation that may cause high homocysteine levels and low folate levels in the bloodstream, among other essential nutrients. Healthcare professionals believe that a variety of health issues, such as inflammation, may be associated with an MTHFR gene mutation. In the following article, we will discuss the MTHFR gene mutation and how it can ultimately affect your overall health.
Contents
What is an MTHFR Gene Mutation?
People can have single or multiple mutations, as well as neither, on the MTHFR gene. The different mutations are often referred to as “variants”. A variant occurs when the DNA of a specific part of a gene is different or varies from person to person. People that have a heterozygous or single variant of the MTHFR gene mutation have a decreased risk of developing health issues like inflammation and chronic pain, among other diseases. Moreover, healthcare professionals also believe that people that have homozygous or multiple variants of the MTHFR gene mutation may ultimately have an increased risk of disease. There are two MTHFR gene mutation variants. These specific variants include:
C677T. Approximately 30 to 40 percent of people in the United States have a mutation at gene position C677T. About 25 percent of Hispanics and about 10 to 15 percent of Caucasians are homozygous for this variant.
A1298C. There are limited research studies for this variant. A 2004 study focused on 120 blood donors of Irish heritage. Of the donors, 56 or 46.7 percent were heterozygous for this variant and 11 or 14.2 percent were homozygous.
Both C677T and A1298C. It�s also possible for people to have both C677T and A1298C MTHFR gene mutation variations, which includes one copy of each.
What are the Symptoms of an MTHFR Gene Mutation?
Symptoms of an MTHFR gene mutation can be different from person to person and from variant to variant. It’s important to remember that further research around MTHFR gene mutation variants and their effects on health are still needed. Evidence regarding how MTHFR gene mutation variants are associated with a variety of other health issues is currently lacking or it has been disproven. Conditions that have been suggested to be associated with MTHFR variants include:
anxiety
depression
bipolar disorder
schizophrenia
migraines
chronic pain and fatigue
nerve pain
recurrent miscarriages in women of child-bearing age
pregnancies with neural tube defects, like spina bifida and anencephaly
cardiovascular and thromboembolic diseases (blood clots, stroke, embolism, and heart attacks)
acute leukemia
colon cancer
What is the MTHFR Diet?
According to healthcare professionals, eating foods with high amounts of folate may help naturally support low folate levels in the bloodstream associated with MTHFR gene mutation variants.�Good food choices can include:
fruits, such as strawberries, raspberries, grapefruit, cantaloupe, honeydew, banana.
juices like orange, canned pineapple, grapefruit, tomato, or other vegetable juice
veggies, such as spinach, asparagus, lettuce, beets, broccoli, corn, Brussels sprouts, and bok choy
proteins, including cooked beans, peas, and lentils
peanut butter
sunflower seeds
People with MTHFR gene mutations may also want to avoid eating foods that have the synthetic form of folate, folic acid, however, the evidence is not clear if that�s beneficial or necessary. Supplementation may still be recommended for people with MTHFR gene mutation variants. Furthermore, always make sure to check the labels of the foods you buy, as this vitamin is added to many enriched grains like pasta, cereals, bread, and commercially produced flours.
For information regarding the MTHFR and its effects on health issues like cancer, please review this article:Folate, Methyl-Related Nutrients, Alcohol, and the MTHFR 677C >T Polymorphism Affect Cancer Risk: Intake Recommendations
MTHFR, or methylenetetrahydrofolate reductase, gene mutations may cause high homocysteine levels and low folate levels in the bloodstream. We believe that a variety of health issues, such as inflammation, may be associated with an MTHFR gene mutation. People can have single or multiple MTHFR gene mutations, as well as neither. The different mutations are often referred to as “variants”. People that have a heterozygous or single variant of the MTHFR gene mutation have a decreased risk of developing health issues like inflammation and chronic pain. Moreover, doctors also believe that people that have homozygous or multiple variants of the MTHFR gene mutation may ultimately have an increased risk of disease. The two MTHFR gene mutation variants are�C677T, A1298C, or both C677T and A1298C. Symptoms of an MTHFR gene mutation can be different from person to person and from variant to variant. Following what is referred to as the MTHFR diet can ultimately help improve overall health in people with MTHFR gene mutation variants. Also, adding these foods into a smoothie can be an easy way to add them into your diet. – Dr. Alex Jimenez D.C., C.C.S.T. Insights
Protein Power Smoothie
Serving: 1Cook time: 5 minutes
� 1 scoop protein powder
� 1 tablespoon ground flaxseed
� 1/2 banana
� 1 kiwi, peeled
� 1/2 teaspoon cinnamon
� Pinch of cardamom
� Non-dairy milk or water, enough to achieve desired consistency
Blend all ingredients in a high-powered blender until completely smooth. Best served immediately!
Leafy Greens Hold the Key to Gut Health
A unique type of sugar found in leafy greens can help feed our beneficial gut bacteria. Sulfoquinovose (SQ) is the only known sugar molecule to be made up of sulfur, an extremely essential mineral in the human body. The human body uses sulfur to produce enzymes, proteins, and a variety of hormones as well as antibodies for our cells. A fast and easy way to get leafy greens into your diet is to toss a couple of handfuls of them into a delicious smoothie!
The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require additional explanation as how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at�915-850-0900. The provider(s) Licensed in Texas*& New Mexico*�
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
Marcin, Ashley. �What You Need to Know About the MTHFR Gene.� Healthline, Healthline Media, 6 Sept. 2019, www.healthline.com/health/mthfr-gene#variants.
Those who like to jog or run say there is nothing like the feeling of jogging and running. The breeze all around, the sound of feet hitting the pavement, and the accomplishment felt after. Jogging and running can generate empowerment that makes individuals feel like they’re on top of the world. Until back pain rears its ugly head.
Many individuals with back pain see no alternative and so give up trying to jog or run and just forget the whole thing. However, it is possible to be a successful runner and hold down a jogging/running regiment, even with back pain. �
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Jogging and Running
Running can be highly beneficial for those with back pain. Aerobic exercise is considered a form of effective treatment for low back pain. Other studies have found that runners have stronger spines. An article published in Scientific Reports looked at the intervertebral�discs in joggers/runners, as well as, non-joggers/runners. The joggers/runners had healthier intervertebral�discs.
Running can be quite helpful to those having trouble with mechanical back pain. Mechanical means an individual has a structurally sound spine but has a job/ that creates force/s that can damage tissues, which results in back pain. Often, those with back problems have a weak:
Core
Front
Back
� Jogging and running can help strengthen the core along with weight loss and improved fitness will definitely benefit the spine/back. Jogging and running increases endorphins. This is great for the brain and mood and decreases overall general pain.
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Individuals that should not be jogging or running
It does not mean these individuals cannot jog or run. But because of underlying conditions, they need to talk to their doctor first and may have to take extra precautions.
Back pain can be mechanical or structural. If the spine has a structural problem, then jogging or running might not be the best option for a therapeutic exercise regiment/program. This can be dangerous as any added stress placed on an abnormal spine could worsen symptoms, instead of helping to reduce back pain. It could even worsen the condition. This is where the proper spine treatment is directed by a doctor, spine specialist, chiropractor, or physical therapist.
� If the back pain is mechanical, there are ways to work in a running program while keeping the back safe. Usually, this means stretching out, getting physical therapy, and applying heat, and ice. These can all help while being able to jog and run.
Lace-up, make sure there is plenty of water and hit the neighborhood, trail, pathway, etc. However, running with back pain is not the most optimal way to jog or run. Here are some ways to get the full benefits from the experience.
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Stretching Out
Stretching is highly beneficial not only to runners, but everyone, especially those with back pain, which is why stretching before and after jogging and running is extremely important.
The hamstrings, quadriceps, groin, and calf muscles definitely need to be stretched out. These are the legs muscles and need to be loose and ready to move. The thigh muscles are all directly connected to the pelvis and hip. If they are not properly stretched it can affect pelvic tilt and generate low back tightness.
The calf muscles are not directly connected, but the body is a kinetic chain, which means that the body works as a whole unit. For example, let’s say an individual has a tight calf or Achilles tendon. This can change stride length, which can then affect the hamstrings, hips, and back. Icing the back after a jog or run will reduce back pain and inflammation. �
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Ease Into The Routine
Experienced runners know all too well that literally hitting the ground and taking off results inpain and injuries. First-time joggers/runners, as well as those coming back to jogging or running need to take it low and slow. This means to gradually ease into a jogging/running routine rather than trying for ten miles right away.
Go for reasonable goals that can be accomplished. This will increase the likelihood to stay with it and continue. This goes for new runners or joggers/runners making a return. Gradually increasing distance and speed is the safest approach. Gradual increases in the jog or run allow for positive and progressive gains.
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Mix In Other Workouts
Cross-fit training can help the body take a break when carrying out a running program. Cross-fit training involves:
Swimming
Biking
Weights
A comprehensive exercise program should include resistance training and cardiovascular exercises. Only want to stick to only running and nothing else then change distances and speeds on a regular basis. Changing running workouts frequently will help to avoid overuse injuries.
Overuse injuries can stop an exercise routine cold. Therefore, making sure that the body gets the proper amount rest between jogs, runs, and workouts is crucial for the therapy to work, to eventually alleviate back pain. �
Proper Equipment
Throwing on a pair of old sneakers and jogging out the door is not the way to go. Improper shoes could exacerbate the back pain/condition and even create new injury/s. Therefore choosing the proper jogging and running equipment will prevent injuries and back pain.
Shoes, braces, and orthotics do make a difference. Just like using the right tool for a job makes a difference. Especially, when using a cheap knock-off that breaks or falls apart. It is the same with exercise equipment/gear. For the low back, a neoprene belt can help the low back remain loose by providing heat and spine support.
Shoes and orthotics are important, but be sure to know foot size and type. Otherwise, they could worsen back pain or cause another injury. Effectively utilizing them, a runner should get a custom foot orthotic/s sizing. Because every person is unique, functional custom foot orthotics can help balance a person�s unique body structure. Dr. Jimenez can help provide functional custom foot orthotics to patients who want to improve back pain. For example, some things to consider:
Some choices depend on the constant surface the runner is on, like cement, pavement, trail, or dirt road. Specialty running shoe stores can provide a foot strike analysis to find the shoes that are best matched for your physical needs. �
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Feel That, Your Body’s Telling You Something
Experienced athletes, especially runners know how to listen to their bodies. If an injury is acting up they take the necessary time off to heal properly before re-starting the regiment. For those with back pain, this is especially important during the program.
If back pain presents mid-run, it is recommended to slow down. If that doesn�t bring relief then stop and stretch. And if that does not help then stop the workout altogether. It could be nothing and all that is needed is more rest before starting up again. But if it persists then check with your doctor, chiropractor, or physical therapist to re-evaluate the program, as there could be some changes/adjustments that need addressing.
It does not matter, whether it is back pain, shin splints, or plantar fasciitis, the point is to listen to your body. Pain that lingers on or wakes you out of sleep should be checked out.
Chiropractors On Metabolic Syndrome & Inflammation
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Dr. Alex Jimenez�s Blog Post Disclaimer
The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.*
Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require an additional explanation as to how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at�915-850-0900. The provider(s) Licensed in Texas& New Mexico
Calories are defined as a measurement of the energy our body produces from the foods we eat. However, not all calories are created equal. If we were to eat nothing but spoonfuls of sugar all-day, by way of instance, our health would tremendously deteriorate because there simply aren’t enough nutrients in those calories from sugar. The human body needs a variety of nutrients, vitamins, minerals, and many other compounds in order to function properly.
The foods we eat are made up of calories as well as complex mixtures of nutrients, fiber, and additives. This can ultimately affect the hormones that regulate our hunger, known as leptin, and those that manage how we burn or store calories to be used for energy, known as insulin. Our bodies are naturally programmed to protect us against long-term starvation by storing excess calories as fat. Eating “bad” calories in excess amounts can ultimately lead to obesity.
In a research study, a group of people was given the same amount of calories but from different food sources. The participants had no significant weight gain, regardless of whether the calories were from carbohydrates, proteins, fats, or any other combination of nutrients. However, environmental factors, such as an individual’s hormonal balance, emotions, and cravings were not taken into consideration. It’s important to understand how calories can affect your health.
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Good Calories vs Bad Calories
Excess calories from processed foods are stored as fat which can lead to obesity. In the United States, obesity is the main cause of health issues like insulin resistance. Insulin is a hormone that regulates blood sugar levels. It is naturally produced in the pancreas and helps move excess glucose from the bloodstream into the cells to be used for energy. When the pancreas recognizes high blood sugar levels, it creates more insulin to reduce glucose.
However, this can diminish the pancreas of insulin-producing cells which can eventually cause insulin resistance or impaired insulin sensitivity. If the pancreas can’t produce enough insulin, it can lead to prediabetes or type 2 diabetes. Excess calories from sugar and processed foods can also cause inflammation which may also lead to chronic pain. So what can we do to prevent these health issues? The answer is simple: eat complex carbohydrates, lean protein, and healthy fats.
Replace highly processed carbohydrates that can increase blood sugar levels and insulin, with vegetables, beans, and whole grains. When it comes to eating complex carbohydrates like whole grains, the less processed the better! Consider eating stone-ground whole wheat, quinoa, oats, and brown rice. Then, choose lean proteins, such as fish and chicken. as well as healthy fats that come from plant sources, such as nuts, olive oil, and avocado, among others.
Below, we will compare the calories in common foods and drinks to demonstrate the differences and similarities in good calories vs bad calories:�
Can you tell which are the good calories and which are the bad calories? It�s important to follow the principle of �clean eating� and choose unprocessed foods in the purest forms instead of processed foods. This includes foods like fruits, vegetables, legumes, nuts, or eggs. You can eat these foods without worrying too much about your daily caloric intake limit. Eating a variety of these is essential in order to provide your body with the nutrients it needs to function properly.
Bad calories include processed foods which follow exactly the opposite principle of “clean eating”. Foods with high amounts of sugar and fast food offers you almost no nutrients but a lot of what we call “empty calories”. If you�re trying to lose weight to manage insulin resistance associated with type 2 diabetes, you�ll have to pay attention to your �bad� calorie intake.
For more information regarding the effects of good calories vs bad calories on obesity, please review this article:Is the calorie concept a real solution to the obesity epidemic?
Our body needs nutrients, vitamins, minerals, and many other compounds from calories in order to function properly. Calories are a measurement of the energy our body produces from the foods we eat. But, not all calories are created equal. Eating bad calories vs good calories can affect the hormones that regulate our hunger and those that manage how we burn or store calories to be used for energy. Moreover, eating “bad” calories in excess amounts can cause obesity. It’s important to understand how calories can affect your health. In the United States, obesity is the main cause of health issues like insulin resistance and type 2 diabetes. Excess bad calories can also cause inflammation which may cause chronic pain. Eating complex carbohydrates, lean protein, and healthy fats can help people lose weight and prevent as well as control health issues like insulin resistance and type 2 diabetes. Learning to identify good calories and bad calories is a helpful strategy for people who want to improve their overall health. Adding healthy foods to a smoothie can also be a fast and easy way to include good calories into your diet. – Dr. Alex Jimenez D.C., C.C.S.T. Insights
Zesty Beet Juice
Servings: 1Cook time: 5-10 minutes
� 1 grapefruit, peeled and sliced
� 1 apple, washed and sliced
� 1 whole beet, and leaves if you have them, washed and sliced
� 1-inch knob of ginger, rinsed, peeled and chopped
Juice all ingredients in a high-quality juicer. Best served immediately.
Add Nasturtium to Your Smoothies
Adding nasturtium flowers and leaves to any smoothie can add extra nutrients. These lovely plants are easy to grow and the entire plant is edible. Nasturtium leaves are high in vitamin C, which is essential for a healthy immune system, and they also contain calcium, potassium, phosphorus, zinc, copper, and iron. According to healthcare professionals, the extract from the flowers and leaves have antimicrobial, antifungal, hypotensive, expectorant, and anticancer effects. Antioxidants in garden nasturtium occur due to its high content of compounds such as anthocyanins, polyphenols, and vitamin C. Due to its rich phytochemical content and unique elemental composition, the garden nasturtium may be used in the treatment of a variety of health issues, including respiratory and digestive problems. Not to mention, the flowers and leaves look absolutely lovely in smoothies.
The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require additional explanation as how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at�915-850-0900. The provider(s) Licensed in Texas*& New Mexico*�
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
Glassman, Keri. �The Difference Between Good and Bad Calories.� Women’s Health, Women’s Health Media, 11 June 2019, www.womenshealthmag.com/food/a19930112/the-difference-between-good-and-bad-calories/.
Denner, Julia. �Good Calories Vs. Bad Calories >> The Difference Matters.� Adidas Runtastic Blog, Adidas Runtastic Blog Media, 9 Sept. 2019, www.runtastic.com/blog/en/good-calories-vs-bad-calories/.
Taubes, Gary. �Good Calories Bad Calories: Fats, Carbs, and the Controversial Science of Diet and Health.� CrossFit, CrossFit Media, 31 Jan. 2020, www.crossfit.com/health/good-calories-bad-calories.
A bone graft is defined as using bone-in spine fusion surgery. Spinal fusion’s purpose is to link or weld bones together, in this case, the spinal bones. There are a variety of spinal conditions cause instability and pain:
Degenerative disc disease
Scoliosis
Trauma from an auto accident, sports injury, slip, and fall accident
Spine surgeons use a bone graft to:
Stop motion between two or more vertebrae
Stabilize a spinal deformity
Repair fractures of the spine
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Contents
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Spinal Fusion Stimulates New Bone Growth
A bone graft does not heal or fuse the spine instantly. Rather a bone graft sets up a foundational frame for the individual’s body to generate and grow new bone. A bone graft stimulates new bone production. It is when this new bone begins to grow and solidify, that fusion takes place.
With these types of surgeries, instrumentation like screws, and rods are typically used for the beginning stabilization. But it is the actual healing of the bone that welds the vertebrae together creating long-term stability.
A bone graft can be used for structural purposes for supporting the spine, usually this is done in place of a disc or bone that was removed. Or it can be an onlay, this means that a mass of bone fragments will grow together to stabilize the spine bridging the joint.
There are two generalized bone graft types:
Real bone
Substituted bone graft
Real bone can come from the patient, which is called an auto-graft or from a donor’s bone, called an allograft.
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The Individual’s Bone or Auto-graft
An auto-graft is bone taken or harvested from the individual’s body and transplanted to a specific area, in this case, the spine. An auto-graft is considered the gold standard because it is the individual’s own bone, which contains:
These all help to stimulate the healing of the fusion. There are advantages for an auto-graft, which include a higher probability for fusion success and a lower risk for disease transmission. The only real setback for individuals of an auto-graft is the post-operative pain that usually comes with the procedure when harvesting an individuals’ bone. Bone can be harvested from one of the individual’s:
Iliac crests
Pelvic bones
Ribs
Spine
� Bone graft harvesting creates a new set of risks. These include:
Because of these risks and the possibility that the bone could be poor quality, a surgeon could decide to use another type of bone graft. When this happens a surgeon could go with what is known as a local auto-graft. This is bone harvested from the decompression itself.
These are the parts that are removed to decompress the nerves. They usually consist of bone spurs, lamina, and portions of the spinous process. These same bone pieces can be reused to assist with the fusion of the decompressed areas.
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Donor Bone or Allograft
An allograft is a bone harvested from another person, usually from a tissue bank. Tissue banks harvest bone and other tissues from cadavers for medical purposes. An allograft is prepared by freezing or freeze-drying the bone or tissues. This helps limit the risk of graft rejection. Bone from an allograft does not have living bone cells and is not as effective at fusion stimulation when compared to an autograft. However, it still does work. Tissue banks:
Screen all their donors
Supervise bone recovery
Test donations
Sterilize donations
Store for use
Look for tissue banks that are accredited by the American Association of Tissue Banks. US Food and Drug Administration has strict regulations when it comes to human cell and tissue processing. These include rules about the eligibility of donors. These guidelines/protocols help reduce the risk of tissue contamination and the spread of disease.
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Bone Graft Substitute
These substitutes are man-made or are made from a manipulated version of a natural product. These alternatives are safe and can provide a solid foundation for the individual’s body to grow bone. Substitutes have similar properties of human bone, which include a porous structure and proteins that stimulate healing.
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Demineralized Bone Matrix – DBM
A demineralized bone matrix is an allograft that has gone through a process where the mineral content has been removed. This demineralization helps reveal bone-forming proteins like collagen, and growth factors hidden within the bone that can stimulate healing.
This procedure is often considered a bone graft extender. It is not considered a replacement. This is because its ability to fuse the human spine on its own has not been proven. DBM can be combined with the regular bone for more volume and is available in these forms:
Chip
Granule
Gel
Powder
Putty
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Ceramic-based Extenders
Ceramic-based extenders are mixed in combination with other sources of bone. This is because they consist of calcium matrix for fusion, but there are no cells or proteins to stimulate the healing process. These include:
Ceramic-based extenders do not present a risk for disease transfer but can cause inflammation. They are available in porous and mesh forms.
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Morphogenetic Protein – BMP
Different types of bone morphogenetic proteins or BMP’s are used to stimulate new bone growth. These proteins are found in human bone, however, they are trace amounts. They are then produced in larger amounts through genetic engineering.
This all depends on the type of spine surgery an individual undergoes. Bone morphogenetic protein could be considered an option in promoting new bone growth along with healing fusion.
Nutrition is considered to be one of the most well-understood environmental factors associated with changes in the epigenome. Nutrients in the foods we eat are processed by our metabolism and turned into energy. One metabolic pathway, however, is responsible for producing methyl groups or fundamental epigenetic marks that regulate our gene expression. Essential nutrients, such as B vitamins, SAM-e (S-Adenosyl methionine), and folic acid are important components in this methylation process. Diets with high amounts of these essential nutrients can quickly change gene expression, especially during early development. In the following article, we will discuss the connection between nutrition and the epigenome.
Contents
Nutrigenomics and Health
Healthcare professionals discuss that when it comes to dealing with health issues like inflammation and chronic pain, understanding how nutrigenomics affects our overall health is important. Nutritional genomics, or nutrigenomics, is a science that studies the relationship between nutrition, health, and the genome. Researchers in the nutrigenomics field believe that changes in epigenetic marks may be associated with a variety of health issues, including inflammation or the development of diseases like obesity, heart problems, and cancer. Studies have demonstrated that we may be able to control the effects of the nutrients we eat in order to change gene expression associated with various health issues.
Approximately more than 1 out of 3 adults in the United States have been diagnosed with obesity which ultimately increases the risk of a variety of health issues, including prediabetes and type 2 diabetes, among other diseases. Previous studies have demonstrated that changes in epigenetic marks during early development may even predispose individuals to obesity. Moreover, changes in epigenetic marks were also demonstrated to affect metabolic pathways that may increase the risk of prediabetes and type 2 diabetes. Healthcare professionals in the nutrigenomics field have created new ways to be able to better find balance through a wholesome understanding of nutrition and the epigenome.
“An epigenetic test can provide data that is useful for healthcare professionals. It may also offer information about how certain metabolic pathways are affected by essential nutrients, such as vitamins and minerals”.
What is the Epigenetics Diet?
The term “epigenetics diet” was first coined by Dr. Trygve Tollefsbol in 2011. It is medically defined as a group of compounds, such as resveratrol in red grapes, genistein in soybeans, isothiocyanates in broccoli, and many other well-known types of foods, which have been demonstrated to help change epigenomic marks and gene expression. According to researchers, the epigenetics diet can prevent the progression of tumors by regulating enzymes that control these epigenomic marks and gene expression, including DNA methyltransferases, histone deacetylases, and certain non-coding RNAs. Several types of foods included in the epigenetics diet are demonstrated in the following infographic:
Researchers used recently advanced technologies that demonstrated how several bioactive compounds may aggravate damage to the epigenome caused by environmental pollutions. By way of instance, dietary supplementation with methyl donors, such as vitamin B12, choline, and folate, among others, as well as the isoflavone genistein, can regulate changes to epigenome marks and gene expression caused by bisphenol A, a hormone-disrupting chemical. B vitamins may also prevent the loss of DNA methylation caused by air pollution. According to these same studies, dietary supplementation with folic acid has also been demonstrated to help prevent the negative side-effects caused by heavy metals.
We believe that foods in the epigenetics diet could be used to counteract changes to gene expression and epigenomic marks caused by environmental pollution. Environmental pollutants in several types of foods, such as pesticides in fruits like strawberries and leafy greens like spinach, bisphenol A in the plastic containers of foods and drinks, dioxins in fatty foods, polycyclic aromatic hydrocarbons produced when meat is grilled or smoked at high temperatures, and mercury in several types of seafood like king mackerel and swordfish, have been associated with changes to epigenomic marks and gene expression. Those exposures, especially during early development, may cause various health issues.
For more information regarding the connection between nutrition and the epigenome, please review this article:Nutrition and the Epigenome
Nutrition is one of the most understood environmental factors associated with changes in epigenomic marks and gene expression. Essential nutrients found in the different types of foods we eat are metabolized and turned into molecules in order to be used for energy by the human body. One metabolic pathway is responsible for creating methyl groups, important epigenetic marks that regulate our gene expression and epigenomic marks. Essential nutrients, including B vitamins, SAM-e (S-Adenosyl methionine), and folic acid are fundamental components in DNA methylation. Diets that are rich in these essential nutrients can quickly change epigenetic marks and gene expression, especially during early development. Furthermore, adding a variety of good foods to a smoothie can be a fast and easy way to add essential nutrients to your diet. Below is a fast and easy smoothie recipe to help feed your genes. – Dr. Alex Jimenez D.C., C.C.S.T. Insights
Ginger Greens Juice
Servings: 1Cook time: 5-10 minutes
� 1 cup pineapple cubes
� 1 apples, sliced
� 1-inch knob of ginger, rinsed, peeled and chopped
� 3 cups kale, rinsed and roughly chopped or ripped
� 5 cups Swiss chard, rinsed and roughly chopped or ripped
Juice all ingredients in a high-quality juicer. Best served immediately.
Add Nasturtium to Your Smoothies
Adding nasturtium flowers and leaves to any smoothie can add extra nutrients. These lovely plants are easy to grow and the entire plant is edible. Nasturtium leaves are high in vitamin C, which is essential for a healthy immune system, and they also contain calcium, potassium, phosphorus, zinc, copper, and iron. According to healthcare professionals, the extract from the flowers and leaves have antimicrobial, antifungal, hypotensive, expectorant, and anticancer effects. Antioxidants in garden nasturtium occur due to its high content of compounds such as anthocyanins, polyphenols, and vitamin C. Due to its rich phytochemical content and unique elemental composition, the garden nasturtium may be used in the treatment of a variety of health issues, including respiratory and digestive problems. Not to mention, the flowers and leaves look absolutely lovely in smoothies.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask�Dr. Alex Jimenez�or contact us at�915-850-0900.
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
Kirkpatrick, Bailey. �Epigenetics, Nutrition, and Our Health: How What We Eat Could Affect Tags on Our DNA.� What Is Epigenetics?, What Is Epigenetics? Media, 11 May 2018, www.whatisepigenetics.com/epigenetics-nutrition-health-eat-affect-tags-dna/.
Li, Shizhao, et al. �The Epigenetics Diet: A Barrier against Environmental Pollution.� On Biology, BMC Media, 23 May 2019, blogs.biomedcentral.com/on-biology/2019/05/20/the-epigenetics-diet-a-barrier-against-environmental-pollution/.
Insulin is an essential hormone that regulates blood sugar levels. It is naturally produced in the pancreas and helps move excess glucose from the bloodstream into the cells to be used for energy. When the pancreas recognizes high blood sugar levels, it creates more insulin to reduce glucose. However, this can diminish the pancreas of insulin-producing cells which can eventually cause insulin resistance or impaired insulin sensitivity. If the pancreas can’t produce enough insulin, it can lead to prediabetes or type 2 diabetes. In the following article, we will discuss natural ways to improve insulin resistance or impaired insulin sensitivity to prevent and regulate prediabetes and type 2 diabetes, among other health issues.
Contents
Foods to Avoid with Insulin Resistance
If you have insulin resistance or impaired insulin sensitivity associated with prediabetes, type 2 diabetes, or any other health issue, there are several types of foods that can increase blood sugar levels. Frequently eating foods with high glucose content can diminish the insulin-producing cells that can ultimately affect the human body’s ability to produce enough insulin. When this occurs, high blood sugar levels remain elevated which can ultimately cause prediabetes and type 2 diabetes as well as lead to a variety of other health issues, including damage to organs such as the eyes and kidneys or limbs (neuropathy). Avoid eating the following types of foods if you have insulin resistance or impaired insulin sensitivity:
fried foods
processed snacks and foods
dairy products from cows, such as milk
foods high in saturated fats, such as butter, and salt pork
refined grains, such as white rice, pasta, bread, and flour-based foods
sugary sweets and pastries, such as ice cream, chocolate bars, and cupcakes
starchy vegetables, such as corn, potatoes and yams (without skin), and pumpkin
sweetened drinks or beverages, such as fruit juices, fountain drinks, and sodas
alcohol, such as beer and grain alcohol, in large quantities
Foods to Eat with Insulin Resistance
Many people are commonly deficient in essential nutrients, such as calcium, potassium, magnesium, and fiber. These nutrients are necessary for regulating blood sugar levels. People with insulin resistance or impaired insulin sensitivity, or any other health issue, including prediabetes or type 2 diabetes, should eat foods that have plenty of these essential nutrients. According to the American Diabetes Association, people with insulin resistance or impaired insulin sensitivity can eat from any of the basic food groups, however, it’s fundamental for individuals to understand which types of foods can increase blood glucose levels. Eat from the following types of foods if you have insulin resistance or impaired insulin sensitivity:
antioxidant-rich foods, such as berries
citrus fruits, such as oranges, lemons, and limes
non-starchy vegetables, such as dark leafy greens, peppers, and broccoli
protein-rich foods, such as legumes, nuts, soy, fish, and lean meats
high-fiber foods, including beans, and lentils
omega-3 fatty acid-rich foods, such as sardines, herring, and salmon
certain types of whole grains, such as oats, quinoa, and barley
water, especially as a substitute for sweetened drinks and
unsweetened teas
Exercise to Improve Insulin Resistance
Eating good foods and avoiding bad foods can help improve insulin resistance or impaired insulin sensitivity, however, there’s another natural way to improve this health issue: exercise. Participating and engaging in regular exercise helps improve insulin resistance or impaired insulin sensitivity associated with prediabetes and type 2 diabetes, among other health issues, by moving sugar from the bloodstream into the muscles to be used for energy. The American Heart Association recommends approximately 150 minutes of exercise every week for adults. Participating or engaging in exercise on a daily basis can improve high blood sugar levels as well as promote overall health and wellness.
For more information regarding how to naturally improve insulin resistance, please review this article:
Insulin is an essential hormone that is naturally produced in the pancreas to help regulate blood sugar levels and move excess sugar from the bloodstream into the cells to be used for energy. When the pancreas senses high blood sugar levels in the blood, it creates more insulin to help reduce glucose. However, this can decrease the amount of insulin-producing cells in the pancreas which can cause insulin resistance or impaired insulin sensitivity. If the pancreas can’t produce enough insulin, it can ultimately lead to prediabetes or type 2 diabetes, among other health issues. There are several natural ways to improve insulin resistance or impaired insulin sensitivity to prevent and regulate prediabetes and type 2 diabetes, including eating good foods, avoiding bad foods, and exercising. Furthermore, adding a variety of good foods to a smoothie can be a fast and easy way to add nutrients to your diet. – Dr. Alex Jimenez D.C., C.C.S.T. Insights
Sweet and Spicy Juice
Servings: 1 Cook time: 5-10 minutes
1 cup honeydew melons
3 cups spinach, rinsed
3 cups Swiss chard, rinsed
1 bunch cilantro (leaves and stems), rinsed
1-inch knob of ginger, rinsed, peeled, and chopped
2-3 knobs whole turmeric root (optional), rinsed, peeled, and chopped
Juice all ingredients in a high-quality juicer. Best served immediately.
Eat Mushrooms
One simple thing we can do to improve the microbiome!
Mushrooms feed bacteria in the gut. They are rich in chitin, hemicellulose, ? and ?-glucans, mannans, xylans, and galactans. They are also amazing prebiotics that promotes the growth of gut microbiota, equalling health benefits.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask�Dr. Alex Jimenez�or contact us at�915-850-0900.
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
Raman, Ryan. �14 Natural Ways to Improve Your Insulin Sensitivity.� Healthline, Healthline Media, 17 May 2017, www.healthline.com/nutrition/improve-insulin-sensitivity.
Felman, Adam. �Diet and Insulin Resistance: Foods to Eat and Diet Tips.� Medical News Today, MediLexicon International, 27 Mar. 2019, www.medicalnewstoday.com/articles/316569#foods-to-eat.
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Can you tell which are the good calories and which are the bad calories? It�s important to follow the principle of �clean eating� and choose unprocessed foods in the purest forms instead of processed foods. This includes foods like fruits, vegetables, legumes, nuts, or eggs. You can eat these foods without worrying too much about your daily caloric intake limit. Eating a variety of these is essential in order to provide your body with the nutrients it needs to function properly.
Bad calories include processed foods which follow exactly the opposite principle of “clean eating”. Foods with high amounts of sugar and fast food offers you almost no nutrients but a lot of what we call “empty calories”. If you�re trying to lose weight to manage insulin resistance associated with type 2 diabetes, you�ll have to pay attention to your �bad� calorie intake.
For more information regarding the effects of good calories vs bad calories on obesity, please review this article:
Researchers used recently advanced technologies that demonstrated how several bioactive compounds may aggravate damage to the epigenome caused by environmental pollutions. By way of instance, dietary supplementation with methyl donors, such as vitamin B12, choline, and folate, among others, as well as the isoflavone genistein, can regulate changes to epigenome marks and gene expression caused by bisphenol A, a hormone-disrupting chemical. B vitamins may also prevent the loss of DNA methylation caused by air pollution. According to these same studies, dietary supplementation with folic acid has also been demonstrated to help prevent the negative side-effects caused by heavy metals.
We believe that foods in the epigenetics diet could be used to counteract changes to gene expression and epigenomic marks caused by environmental pollution. Environmental pollutants in several types of foods, such as pesticides in fruits like strawberries and leafy greens like spinach, bisphenol A in the plastic containers of foods and drinks, dioxins in fatty foods, polycyclic aromatic hydrocarbons produced when meat is grilled or smoked at high temperatures, and mercury in several types of seafood like king mackerel and swordfish, have been associated with changes to epigenomic marks and gene expression. Those exposures, especially during early development, may cause various health issues.
For more information regarding the connection between nutrition and the epigenome, please review this article:
