by Dr Alex Jimenez | Detoxification, Diets, Functional Medicine, Health, Holistic Medicine, Integrative Functional Wellness, Integrative Medicine, Natural Health, Nutrition, Wellness
People are exposed to toxins, such as pesticides and air pollutants in food and the environment, on a regular basis. Meanwhile, other toxins are produced in the body through normal functions and microbes. That’s why it’s fundamental to support the liver, one of the major detoxification systems in the body. If the liver isn’t working properly, harmful compounds can start to pile up in the cells and tissues, leading to a variety of health issues. Liver detoxification is a two-step process that converts fat-soluble toxins into water-soluble toxins that the body can eliminate accordingly.
In the following article, we will discuss the importance of liver detox, what happens in the two phases of liver detoxification, and how you can support liver detox to promote overall health.
The Importance of Liver Detox
The liver is responsible for the detoxification of all of the harmful compounds and toxins that the body is exposed to on a regular basis. Moreover, it’s fundamental to eliminate these from the liver and the rest of the body regularly to tremendously reduce their negative effects. If toxins start to pile up in the cells and tissues of the liver, it can potentially lead to liver damage as well as a variety of other health issues. By way of instance, toxins are associated with obesity, dementia, and even cancer. And they are also believed to be a factor in chronic health issues, such as fibromyalgia.
There are two main ways that the body eliminates toxins. First, fat-soluble toxins are metabolized in the liver to make them water-soluble. Then, water-soluble toxins are sent directly to the kidneys where these are eliminated in the urine. Another of the body�s safeguards against harmful compounds is that the blood collected from the gut goes to the liver first. The blood from the gut may be especially high in toxins if a person has a leaky gut. Through the detoxification of toxins first, the liver can considerably reduce the number of toxins that reach other organs, such as the brain and heart.
Phases of Liver Detoxification
The liver is one of the main detoxification systems in the body. Detoxification or detox in the liver is separated into two categories. They are known as Phase I and Phase II liver detoxification pathways.
Phase I Liver Detoxification Pathway
The Phase I liver detoxification pathway is the first line of defense against harmful components and toxins. It’s made up of a collection of enzymes known as the cytochrome P450 family. The enzymes help neutralize substances, such as caffeine and alcohol. They offer protection by converting these toxins into less harmful components. However, if the byproducts of the Phase I liver detoxification pathway are allowed to pile up in the liver, they can damage DNA and proteins. It is ultimately the role of the Phase II liver detoxification pathway to make sure that those toxins do not pile up in the liver.
Phase II Liver Detoxification Pathway
The Phase II liver detoxification pathway neutralizes the byproducts of the Phase I liver detoxification pathway as well as that of other remaining toxins. This is done by metabolizing fat-soluble toxins in the liver to make them water-soluble so that they can be eliminated from the body. This process is known as conjugation. Glutathione, sulfate, and glycine are the primary molecules responsible for this process. Under normal conditions, Phase II liver detoxification pathway enzymes produce low levels of glutathione. Under times of high toxic stress, the body increases glutathione production.
We are exposed to toxins like pesticides and air pollutants in the food we eat as well as in the environment every day while other harmful compounds are produced by microbes through normal functions in the body. It’s essential to support liver function because it is our main detoxification system. If the liver isn’t working properly, toxins and harmful compounds can start to pile up in the liver which can eventually cause a variety of health issues. The phases of liver detoxification are a two-step pathway that converts fat-soluble toxins into water-soluble toxins that the body can eliminate accordingly. In the article above, we discussed the importance of liver detox, the phases of liver detoxification, and how you can support liver detox to promote overall health.�- Dr. Alex Jimenez D.C., C.C.S.T. Insight
Zesty Beet Juice
Servings: 1
Cook time: 5-10 minutes
� 1 grapefruit, peeled and sliced
� 1 apple, washed and sliced
� 1 whole beet, and leaves if you have them, washed and sliced
� 1-inch knob of ginger, rinsed, peeled and chopped
Juice all ingredients in a high-quality juicer. Best served immediately.
Just one carrot gives you all of your daily vitamin A intake
Yes, eating just one boiled 80g (2�oz) carrot gives you enough beta carotene for your body to produce 1,480 micrograms (mcg) of vitamin A (necessary for skin cell renewal). That’s more than the recommended daily intake of vitamin A in the United States, which is about 900mcg. It’s best to eat carrots cooked, as this softens the cell walls allowing more beta carotene to be absorbed. Adding healthier foods into your diet is a great way to improve your overall health.
The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require an additional explanation as to how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900. The provider(s) Licensed in Texas*& New Mexico*�
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
- Ask The Scientists Staff. �Liver Detoxification Pathways.� Ask The Scientists, 30 Jan. 2019, askthescientists.com/qa/liver-detoxification-pathways/#:~:text=liver%20detoxification%20pathways.-,Phase%20I%20Liver%20Detoxification%20Pathway,toxins%20into%20less%20harmful%20ones.
- Watts, Todd, and Jay Davidson. �Phases of Liver Detox: What They Do & How to Support Them.� Phases of Liver Detox: What They Do & How to Support Them – Microbe Formulas�, 24 Jan. 2020, microbeformulas.com/blogs/microbe-formulas/phases-of-liver-detox-what-they-do-how-to-support-them.
- DM; Grant. �Detoxification Pathways in the Liver.� Journal of Inherited Metabolic Disease, U.S. National Library of Medicine, 1 July 1991, pubmed.ncbi.nlm.nih.gov/1749210/.
- Dowden, Angela. �Coffee Is a Fruit and Other Unbelievably True Food Facts.� MSN Lifestyle, 4 June 2020, www.msn.com/en-us/foodanddrink/did-you-know/coffee-is-a-fruit-and-other-unbelievably-true-food-facts/ss-BB152Q5q?li=BBnb7Kz&ocid=mailsignout#image=24.
by Dr Alex Jimenez | Detoxification, Functional Medicine, Health, Holistic Medicine, Integrative Functional Wellness, Integrative Medicine, Nutrition, Wellness
The body is capable of eliminating harmful components generated by the production of toxic metabolites and the ingestion of toxic substances. When these overwhelm the organs of detoxification and excretion, the body can store these chemicals in the connective tissues. Detoxification is essential for the restoration of the body�s regulatory mechanisms in order to improve function. In the following article, we will discuss what is detox and how each of the organs of detoxification is responsible for the proper functioning of the organism in general, among other fundamental tasks.
Liver
The liver performs a variety of fundamental tasks, including digestion and hormonal balance. It’s considered to be the body’s main detoxification system. Several functions of the liver include:
- removing harmful compounds like food additives, toxic medications, and excess hormones, etc.
- extracting waste material from the bloodstream and transforming them so that they can be excreted by the kidneys or intestines
- eliminating toxic metabolites and other waste products from intestinal fermentation and putrefaction
- a source of Kupffer�s cells which filter and eliminate foreign invaders, such as bacteria, fungi, viruses and cancerous cells
Kidneys
The kidneys help to purify the blood from harmful compounds, including food additives, toxic medications, excess hormones, and other chemicals, by extracting them from the bloodstream and eliminating them through the urine. For proper filtration of the blood, an individual’s blood pressure and volume should be stable. Furthermore, proper hydration is essential for proper kidney function.
Intestines
The gastrointestinal tract is also responsible for the detoxification and excretion of harmful compounds.�Throughout the different phases of digestion, harmful compounds are extracted and excreted by the liver into the bile and finally into the small intestine in order to continue through the intestinal tract to be eliminated in the stool. In the final phase of digestion, anything that can still be utilized in the colon, such as fiber, is ultimately broken down further with the help of the gut microbiome and it is transported to the liver for detoxification. The intestines are another essential detoxification system.
Respiratory Tract
The respiratory tract, including the lungs and the bronchi, eliminates harmful compounds in the form of carbonic gas. It may also excrete phlegm. Constant irritation by foreign invaders, such as bacteria, fungi, viruses, and cancerous cells, can cause the alveoli to act as an emergency exit for toxins that the liver, kidneys, and the gastrointestinal tract did not succeed in eliminating. These harmful compounds are transported by the bloodstream towards the lungs and bronchi where they are coughed up as phlegm. This phlegm consists of waste resulting from insufficient digestion and excretion.
Skin
The skin is the largest organ of protection and defense. It plays a fundamental role in the elimination of harmful compounds and it can help with kidney function. It evacuates waste products in the form of “crystals” that are soluble in liquids and are then eliminated in the form of sweat through the sweat glands. Crystals are the residues of the metabolism of foods that are high in protein, such as legumes, eggs, dairy products, fish, meats, and cereals. These may also result from an excess of refined sugar. Other types of waste products and harmful compounds are excreted in the form of rashes.
Lymph System
Finally, the lymph system is another main detoxification system. Lymph fluid allows waste products to leave the cells and be carried away to the bloodstream. Lymphatic capillaries are responsible for the defense of the body and purification of the body fluids to maintain its proper functioning.�Other sites of lymphocyte production are the spleen, the thymus, etc. If foreign invaders enter into the body, the production of white blood cells increases rapidly and proportionally to the intensity of the aggression. The lymph nodes that are closest to the site react first to defend and protect the body.
The body is capable of eliminating harmful components generated by the production of toxic metabolites and the ingestion of toxic substances. When these overwhelm the organs of detoxification and excretion, the body can store these chemicals in the connective tissues. Detoxification is essential for the restoration of the body�s regulatory mechanisms in order to improve function. In the following article, we will discuss what is detox and how each of the organs of detoxification, including the liver, kidneys, intestines, respiratory tract, skin, and lymph system, is responsible for the proper functioning of the organism in general, among other fundamental tasks. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
Zesty Beet Juice
Servings: 1
Cook time: 5-10 minutes
� 1 grapefruit, peeled and sliced
� 1 apple, washed and sliced
� 1 whole beet, and leaves if you have them, washed and sliced
� 1-inch knob of ginger, rinsed, peeled and chopped
Juice all ingredients in a high-quality juicer. Best served immediately.
Just one carrot gives you all of your daily vitamin A intake
Yes, eating just one boiled 80g (2�oz) carrot gives you enough beta carotene for your body to produce 1,480 micrograms (mcg) of vitamin A (necessary for skin cell renewal). That’s more than the recommended daily intake of vitamin A in the United States, which is about 900mcg. It’s best to eat carrots cooked, as this softens the cell walls allowing more beta carotene to be absorbed. Adding healthier foods into your diet is a great way to improve your overall health.
The scope of our information is limited to chiropractic, musculoskeletal, physical medicines, wellness, and sensitive health issues and/or functional medicine articles, topics, and discussions. We use functional health & wellness protocols to treat and support care for injuries or disorders of the musculoskeletal system. Our posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate and support directly or indirectly our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. We understand that we cover matters that require an additional explanation as to how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900. The provider(s) Licensed in Texas*& New Mexico*�
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
- Issels, Ilse Marie. �Information on Detoxification and the Organs That Remove Toxins.� Issels Integrative Immuno-Oncology, 22 May 2015, issels.com/publication-library/information-on-detoxification/.
- Dowden, Angela. �Coffee Is a Fruit and Other Unbelievably True Food Facts.� MSN Lifestyle, 4 June 2020, www.msn.com/en-us/foodanddrink/did-you-know/coffee-is-a-fruit-and-other-unbelievably-true-food-facts/ss-BB152Q5q?li=BBnb7Kz&ocid=mailsignout#image=24.
