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The Role of the Microbiome on the Intestinal Permeability El Paso, Texas

The Role of the Microbiome on the Intestinal Permeability El Paso, Texas

With the last article, we talk about how our gut system actually works. With the many microbes that inhabit our intestines, we do try to our best to lead a healthier lifestyle. Here at Injury Medical, local chiropractors and health coaches inform our patients about functional medicine as well as helping them to prevent a leaky gut. Here we will talk more about what the microbiomes in our intestines do when we are exposed to harsh environments.

The Microbiome

The significant role of the microbiome in the epithelial barrier integrity and breakdown. However, we can�t have a conversation with patients about intestinal permeability and food sensitivities without telling them about the role the microbiome plays.

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The Wheat zoomer is rich with data but adds the Gut zoomer with the patients; the results are more accurate.

Microbial Influence on our Intestines

  • Immune influence: One of the leading roles that microbiomes play in the immune system is that it generates byproducts of carbohydrates/fiber fermentation that will influence T-cell differentiation. Without the distinction, we will see an increase of being at high risk of autoimmune diseases, allergies, autism, and asthma.

scfas and tcell differentiation

  • SCFAs (Short Chain Fatty Acids): The food we consume gets fermented for good bacteria to feed on. SCFAs creates fermented fibers by commensal microbes into Butyrate, Propionate, Acetate. These three are essential to the intestinal immune system. These SCFAs can influence T-cells differentiation differently, but it still gets the same results.
  • T-cell Differentiation: na�ve T-cells that activate the immune response to T-regs (police cells) to signal B-cells, and it can be a good thing. But if the T-cells activate and differentiate the wrong cells, it will cause inflammation.

When T-cells differentiation is less abundant, there will be a higher incidence of food sensitivities, autoimmune disease, asthma, and allergies. But when there is an abundance of butyrate, the patients have lower rates of colon cancer and colitis.

Microbial influence

  • Tight Junction: Lactobacillus plantarum and Lactobacillus rhamnosus are the reinforcers for the tight junction while inducing TLR (toll-like receptors) outside the intestinal epithelial walls, as well as increasing the abundance of zonulin-occludin into the tight junction.

SCFAs also play a vital role in the tight junction by lessening the extent propionate, inducing LOX (lipoxygenase) activity and increasing tight junction�s stability while reducing permeability.

Pathogens/Pathobionts: Can be an influence in the epithelial barriers as they can be opportunistic or conditionally pathogenic. Various pathogens like enteropathogenic E.coli can alternate the tight junction�s system. However, if there is a low abundance of L. plantarum, then it will lead to infections and disruption as well as disorganization of the actin cytoskeletons. This can be reversed by incubating the epithelial cells with L. plantarum to create a high density of actin filaments to the tight junction and repair itself.

  • Zonulin, actin, and LPS: In the previous article, zonulin is the �gatekeeper� proteins that are responsible for opening and closing the tight junction. We talked about how if there is a low count of zonulin, it can cause inflammation, but if the zonulins are high, they can increase the IP and may facilitate enteric translocation by disassembling the tight junction. With less zonulin, it can be an overgrowth of b bacteria cells, thus causing more inflammation.

Actins are the structural and functional cells in the tight junction. However, if bacteria enter the actin cell walls, the bacteria will release toxins to the cell walls, it not only damages it but causes it to leak as well. This will make the damage actin cells not only paracellular but also intracellular to the damage actin cell walls.

Actin walls can also be affected when surfactants are involved. Surfactants are food agents and are known to affect the absorption of food substances in the gastrointestinal tract. They are not problematic, but when there is a low count on TEER, it can increase permeability and disband the tight junction.

LPS

LPS (Lipopolysaccharide) acts as a barrier and is recognized by the immune system as a marker for detecting bacterial pathogen invasion. It�s responsible for the development of inflammatory response in our gut.

Diet and Lifestyle

Diet and lifestyle contributions to the epithelial barrier integrity and breakdown. With the Wheat and Gut Zoomer helping out our intestinal barriers. Specific diets and lifestyles can also play effect to what is causing discomfort to our gut. These factors can cause our gut to be an imbalance, gastro discomfort, inflammation on our intestinal epithelial barriers.

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  • Gluten: Gliadin is the main peptide that can cause gluten sensitivity. The gliadin protein can bind with many microbes, causing discomfort to our intestines and gut. Plus giving us an autoimmune disease, skin allergens, and chronic illnesses.

ketogenic-pyramid-s

  • Keto/High Fat Intake: Increase fat meals cause an increase of permeability, and if a patient has a high gram-negative, it will cause problems. But it can be beneficial, to those who don�t have the gram-negative bacteria in their system but, certain microbes like SCFAs do cling onto these fatty substances. In order to give patients an accurate result use both the Gut Zoomer and Wheat Zoomer to better the chances. Higher fat meals suppress beneficial bacteria. Causing a double risk of toxins in the bloodstream as well as inflammation.

a-pint-of-beer-being-poured-which-may-cause-bloating

  • Alcohol: Patients are more willing to give up alcohol than gluten. Alcohol can be a stress reliever but can lead to addiction. It can be one of the causes of redistribution of the junctional proteins. One glass of wine a day is ok, but some patients don�t see alcohol as a mediator for reducing problems.

LECTIN_Molecules

  • Lectins: Lectins are contributors to permeability and impair the integrity of the intestinal epithelial layer, allowing passage through. Antibiotics for WGA can help lower the permeability of the intestinal wall barriers.

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  • Stress: Stress can cause discomfort and permeability in the intestinal epithelial barrier from high levels of cortisol.

Conclusion

Yes, gluten can cause inflammation in the intestinal epithelial barriers, but many factors that we discussed are also factors that can cause physiological assaults on the barrier�s integrity and stability of the intestinal ecosystem. Dr. Alexander Jimenez informs our patients about the importance of how functional medicine works with the combination of the Gut Zoomer and the Wheat Zoomer. This is not only protecting our gut but by giving us the information on what we can do to prevent a leaky gut.

Introducing Wheat Sensitivity and the Wheat Zoomer El Paso, Texas

Introducing Wheat Sensitivity and the Wheat Zoomer El Paso, Texas

Today local chiropractors will be giving a description of the wheat zoomer. We will be giving a brief description of each panel, its markers, and the basic interpretations of the test. We will also be discussing the considerations for the patients and providers before we take The Wheat Zoomer test.

What is a Wheat Zoomer test?

The Vibrant wheat zoomer has 6 test in one to identify if the patient has wheat and gluten sensitivity. The Vibrant wheat zoomer does give our patients a thorough evaluation and we ask our patients if they started to be gluten-free or was gluten-free, either from birth or not and how much gluten-contained food did they eat. One of the best ways to ensure that our patients may have a gluten sensitivity is that if they have a food diary for us to look over and that way we can determine how severe of the wheat zoomer.

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IgA vs IgG

In order for us to know about the wheat zoomer in our patient�s body, we must know about the immunoglobulins. The first one is IgA. IgA immunoglobulins are mucosal and are found primarily in the epithelial lining of the body: intestinal tract, lungs esophagus, blood-brain barrier and around internal organs. They are:

  • The first line of defense.
  • More accurate to our gut.

IgG immunoglobulins found in the blood system and are numerous in the body They are considered �systemic� and are non-specific to any one location. Not all IgG antibodies are sensitive though, some of them can indicate that an antigen has �leaked� into the blood and the immune system tagged that antigen as a �non-self�. And they are not diagnostic as IgG+IgA, but if IgA is absent, the antibodies are more relevant.

  • If the patient is recently gluten-free, the antibodies will tell us that the antigen hasn�t cleared out in the patient�s system from past weeks of eating gluten.

Celiac

Celiac is a growing autoimmune disease, about 1% of the population is affective and 1 in 7 Americans have a reaction to wheat or wheat gluten disorder. The Vibrant test can determine a 99% sensitivity and 100% specify on the celiac antibodies.

  • Total IgA and Total IgG measure both the IgA and IgG to determine the patient�s reactivity to gluten
  • Cut off for IgA is 160 as well as a bottom 1/3rd
  • Not all traditional markers for celiac disease doesn�t need to be elevated if tTg2 is elevated.

Intestinal Permeability

Actin cell structure

Zonulin is the gatekeeper for the intestines and controls nutrient flows and molecules across the membrane. It is a protein complex inside the intestinal tight junctions and can be increased by either gluten and high-fat meals.

Actin

Anti-Actin, especially f-Actin is in the smooth muscle of the intestines. Actin is part of the actomyosin complex. Vibrant can isolate f-Actin to get a more accurate picture of the patient�s immune response to the intestines. While antibodies in actin can identify intestinal destruction and indicate autoimmune diseases like connective tissue disease and autoimmune hepatitis.

lps

Lipopolysaccharide (LPS) is produced by gram-negative enterobacteria. It is very potent and can cause inflammation. Plus it�s one of the indications of a leaky gut. Practitioners can draw additional lab test for cardiovascular, inflammatory markers, and diabetes/insulin resistance.

Here at Injury Medical Clinic, we suggest to our patients to try a Vibrant GutZoomer to identify the source of their ailments before we add the Vibrant WheatZoomer.

Gluten-mediated Autoimmunity

Fusion Peptide is the new addition to Wheat Zoomer in 2017. It is cross-linked to tTg and can identified celiac progression from 14 months to 4 years.

Schematic-illustration-of-liposome-fusion-mediated-by-simple-SNARE-protein-mimics

Differential Transglutaminases can detect autoimmune reactions to gluten that are not celiac or are becoming celiac. However, gluten is still a trigger but react differently in the celiac autoimmune disease such as:

  • Transglutaminase 3= skin manifestations of autoimmunity like dermatitis herpetiformis, eczema, and psoriasis.
  • Transglutaminases 6= neurological manifestations of autoimmunity in the cerebellum like gluten ataxia, gate abnormalities, balance and coordination issues.

Wheat Germ Agglutinin

Wheat Germ Agglutinin is the lectin component of wheat but, it is not a component to gluten. Dr. Jimenez can detect a patient’s low level of Vitamin D absorption from the patient�s results. And Wheat Germ Agglutinin is commonly used as an additive in supplements and the supplement can still be called gluten-free due to the different protein structure.

Gliadin, Glutenin, and Prodynorphin

Gliadin and glutenin are what makes up the super protein in gluten. Most people are reacting to the Gliadin portion of gluten and gliadin binds with tTg2 in celiac and binds zonulin to a leaky gut in patients. Gliadin reacts to any antigens can indicate a sensitivity to gluten in patients and gluteomorphin are peptides in wheat and react as a euphoria receptor to the brain. Prodynorphins antibodies can indicate that gluten reacts to signaling hormones and affect the patient’s mood.

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Sadly though, patients do have a hard time withdrawing gluten in their diet since their antibodies are used to the compound and it up to us, here at Injury Medical Clinic to gently push our patients to have the will power to fix what is causing them to have ailments.

Wheat Allergin

Wheat Allergen is the true allergen body. Some patients that already know that they are allergic to wheat from a young age but it doesn�t decrease when wheat is eliminated and can remain long term after the allergic response happens.

Glutenin

Glutenin is the other part of the gluten compound. However it is less common to some people, but some individuals do show reactivity to glutenin, thus still have a gluten sensitivity. But there is no clinical difference to the reactivity to glutenin from high to low molecular weight.

Non-Gluten Wheat Proteins

Surprisingly Vibrant has an advantage to their test as they have a panel for patients that don�t have a gluten sensitivity but a wheat sensitivity. The Vibrant advantage to the unique non-gluten wheat panel shows us that:

  • Proteins in wheat unrelated to gluten but relevant to immune reactions.
  • It is 30% of the protein molecular weight of wheat.
  • Some individuals are more reactive to wheat proteins than gluten itself.

If they are trying to be gluten-free, patients still have to read the labels to see if any hidden wheat starches are in the ingredients. But not all food products are gluten-free if they have the wheat protein in them.

Conclusion

If the patient is trying to be gluten-free but previously ate gluten compound food. They can still feel the reaction if they discovered that they have a sensitivity to gluten by their practitioner. And must take precautions when they are reading the labels of the products they are going to buy and consume. In the next four articles, we will discuss what the Wheat Zoomer can provide as well as, discussing about what causes leaky gut, what actually goes on in our patient�s intestines, and wrapping up on what to do after the Wheat Zoomer heals and restores the gut barrier.

The Role of the Microbiome on the Intestinal Permeability El Paso, Texas

Gut Microbe Busters El Paso, Texas

Now and days, mostly everyone has a gluten sensitivity or a gluten allergen in their bodies. This could happen to anyone whenever they are eating gluten-contained food or products and suddenly feel unwell or their gut acts differently throughout the day. Or they actually get tested by their physicians and realizes that they have celiac disease. In the last article and the previous one after that, we talked about the 8 products that have hidden gluten in them; as well as the introduction of the wheat zoomer we use for our patients.

 

Here at Injury Medical Clinic, Dr. Alexander Jimenez consults with our patients about certain zoomers that can actually aid the patient�s body. In this article, we review the factors that affect test results such as medication and fasting after taking the Wheat Zoomer, as well as, focusing heavily on the mechanism of the intestinal permeability, the structure and function of the epithelium. We also focus about important immunomodulatory metabolites, epithelial cell types and the roles in the epithelial barrier.

Intestinal Permeability

Let�s start with the mechanisms of intestinal permeability. The main purpose of the intestinal epithelium is to keep the good things in and the bad things out. While the system is complex and ever changing, it still sends out a message to the host and maintain balance both physical and biochemical as a protective barrier.� There is an abundance of antigen sampling to regulates the flow of nutrients in the host�s body, as well as, keeping an eye on the body by the mucosal immune system. Not only that, if you have an injury or an acute inflammation, the intestinal epithelium will support tissue repair by coordinating with microbiota.

Intestines

Another thing that the epithelium does is that it responds to the microbial signals that will make our bodies tolerate any continuous exposure to commensal bacteria. But we do want to keep the good bacteria in our bodies but get rid of the bad bacteria, so our bodies feel good. The intestinal epithelium also convey microbial signals to the mucosal immune cells, while promoting a coordinating immune response to battle against commensal bacteria and the enteric pathogens, since these two microsomes should not be in places they are not allowed in.

 

While the epithelium is battling with the bad bacteria in our system, it also regulates the B and T cell response to either, control inflammation, squash inflammation, or cause inflammation on the intestinal barrier, depending on the situation. Plus the epithelium locally regulates the immune response at the intestinal barrier by influencing innate and adaptive immune responses to the body�s intestines.

 

However, if there is something disrupting the intestines, like chronic inflammation or leaky gut; the epithelium barrier can be compromised. In order for us to fix a leaky gut, we must learn what is causing the inflammation in the first place. The epithelium is home to many microbes, immune cells and can determined if we need the immune response on any harsh exposure. If we can learn more about these mechanisms, then we can calm down the inflammation by resetting it back to its calm, natural state.

 

But the immune cells in our intestinal epithelium can also cause disruption on our gut by leaking out of the protective barriers and attacking the pathogens anywhere in our system. So epithelial permeability can not only cause inflammation but prevent it in our intestines, which is both good and bad depending on the situation.

 

Dr. Alexander Jimenez consults with our patients with natural alternatives of healing inflammation in their gastral intestines.� If he can find the sources of what causes the inflammations in your gut, then he can work with aiding them with functional medicines while informing you what they can do to heal your gut.

 

Now let�s looks at the intestines and the many microsomes that they contain. Here are some microsomes we will be discussing as well as what is their key roles in the intestines; so we can figure out how to prevent a leaky gut.

The Mucosa

This is in both the small intestines and the large intestines and are completely different. The small intestines has one mucus layer and has limited microbes inside it�s mucosa, while the large intestines has an attached inner mucosa and a loose outer mucosa. The mucosa plays an important role in the intestines because it can tell �Friend� from �Foe� in the immune system.

protective mucus layer

Important Tight Junction Proteins

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The tight junction is an important function in the intestinal epithelium as it is one of the barriers that separates what comes in and what comes out in our gut.

Actin.JPG

Actin: Are the structure and functions of tight junctions. But they constantly disassemble and reassemble actin filaments if they are anti-Actins. It is controlling the tight junctions cells as it acts like a contractable belt by pulling or contracting the junctions in the intestinal cells.

Actin cell structure

Zonulin: They are the �gatekeeper� proteins that are responsible for opening or closing the tight junctions. Zonulin acts the mortar of the intestines and is associated when gluten sensitivity is present, if there are low counts of zonulin thus causing inflammation.

lps.JPG

LPS(Lipopolysaccharide): These sent out a signal to the tight junction permeability as they find signs of bacterial endotoxin by translocating across the epithelial barrier and entering circulation. LPS is made up of gram negative bacteria in the GI tract. LPS outside the epithelial cell wall and reacts to fatty acids, which can lead to obesity for individuals.

Cell Receptors Involved in the Barrier Integrity

These cells are protectors of the epithelial barrier walls as they strengthen the immune intolerance and digestive tract, as well as causing or preventing inflammation when necessary.

gprotein

G Protein Coupled Receptors (GPCRs): GPCRs are the main players of the immune system in the epithelial system. A wide variety of substances can bind with GPCRs depending what the substances are. Short chain fatty acids, omega-3�s and any food that we eat is fermented by our gut and stimulate repair on the epithelial barrier. However if there is a consumption of low or zero-fiber in our diet, the food will not be fermented and causes inflammation.

Aryl hydrocarbon receptors

Aryl Hydrocarbon Receptors (AhRs): AhRs interact with a range of aromatic hydrocarbons like food and microbes both in and out of the gut. These receptors respond strongly to compounds found in cruciferous vegetables, thus preventing a heighten immune reaction and reducing epithelial damage as well as promoting functioning intraepithelial lymphocytes (IELs).

But if we are not eating enough cruciferous vegetables, the IELs are being produced less, the epithelial barrier is compromised and will cause inflammation.

BARs

Bile Acid Receptors (BARs): BARs recognize primary and secondary bile acid. The primary bile acids comes from the liver and then transformed into secondary bile acids by microbes. BARs play an important role in in metabolic regulation, however if there is suppression of bile in the GI tract; then the intestinal barrier is more susceptible to destruction. However, if you are producing a low bile count or obstructed bile flow, it can be the result of the microbes translocating to the small intestines and causing mucosal inflammation, SIBO and leaky gut.

Epithelial Cells Involved in the Barrier Integrity

bigcells

These cells are very important to the intestinal epithelial barrier as they can either protect the barrier walls or can lead them to their demised.

Cells

Dendritic cells: Dendritic cells are presenting antigen cells that are found the epithelial layer. These cells sample and present antigens it to Tcells, thus activating immune response. Dendritic cells help the Tcells tell the difference between self and non-self because if we eat commonly consumed foods or foreign antigens are present, we don�t want our immune system to rise up�most of the times.

important cells.JPG

Goblet cells: Goblet cells are very important of the epithelial barrier because they provide the mucus barrier that coats and protects the intestinal walls. Without this mucus barrier, we will sick and any harmful bacteria will come in and out of the intestinal barriers.

enteroedocrine cells.JPG

Enteroendocrine cells: Enteroendocrine cells host receptors and produce a wide range of hormones, enzymes and neurotransmitters that affect or control our appetite, digestive functions, motility and interacts with microbial communities. However, these cells can either be beneficial or not if the host diet is in played.

Mcells.JPG

M cells: Microfold cells or M cells are located over the Peyer�s patches and they constantly sample outside the intestinal epithelial barriers for any microbes that pose a threat. They also present antigens from the outside to the dendritic cells to activate the Tcell response, as well as consuming the antigen by neutralizing it. Without the M cells, we risk of losing tolerance to microbes, thus causing inflammation on our intestinal barriers.

Conclusion

In total, we now have a deeper knowledge of our gut system as well as taking an in depth look on what our intestinal gut goes through to stop inflammation. In order to stop leaky gut, we must change our eating habits gradually when we want a healthier life. Dr. Alexander Jimenez does discuss to our patients the importance of protecting our gut with functional medicine as well as, encouraging our patients to take that first step into a healthy lifestyle.

 

The Connection Between Leaky Gut & Diabetes | Wellness Clinic

The Connection Between Leaky Gut & Diabetes | Wellness Clinic

Many people with diabetes are extremely conscious about their health, for this reason, they are continuously looking for ways to handle their diabetes more efficiently. However,how can they make a difference if they do not even understand the disease they are currently suffering from? Some factors are thought to cause this and make it even worse.

 

Leaky gut is one of those ailments; some also theorize that without a leaky gut, you can’t actually have type 2 diabetes. Not only could it cause diabetes, but it may perpetually make it even worse.

 

What is Leaky Gut?

 

Leaky gut can be called “intestinal hyperpermeability”. In simpler terms, it means that toxins on your gut may pass through the intestines and also leak in your entire body. As can be anticipated, this causes lots of medical problems.

 

Basically, leaky gut occurs when your digestive tract is weak in the poor diet, among other factors. The intestines worn and are currently thinning down. The “good bacteria” which assist you in breaking down your food and eliminating toxins are not flourishing. Leaky gut allows toxins to reside in the body which should have been expelled quite quickly, causing symptoms such as these:

 

  • Inflammation (sometimes severe)
  • Inflammatory bowel disease (Crohn and ulcerative colitis)
  • Irritable bowel syndrome
  • Food allergies
  • Chronic fatigue
  • Hepatitis
  • Pancreatitis
  • Arthritis
  • Diarrhea
  • Joint pain
  • Skin rash
  • Diabetes
  • AIDS

 

With such a lengthy list of conditions related to your leaky gut, you might begin to think it is a super-disease or something. Do not worry, it is not. Though it contributes to or causes some messed up stuff inside your body, it’s avoidable and even reversible. Some professionals even believe you could reverse severe and chronic disease (such as diabetes) by preventing that leaky gut.

 

You won’t discover much about leaky gut from mainstream physicians. Most doctors do not even test this yet. It is really somewhat of a mystery to most medical professionals. Linda A. Lee, MD, a gastroenterologist in John Hopkins Integrative Medicine and Digestive Center says “We do not understand a good deal, but we know that it exists.” She proceeds. “In the absence of evidence, we do not know… what treatments may directly address it.”

 

Other specialists, such as Donald Kirby, MD, refer to a leaky gut as a “very grey area”. Itself is a diagnosis of a disorder, it means that more research needs to be done, and an individualized diagnosis has to be made. What exactly does that mean? It usually means that the root of leaky gut can be any number of items, so you want to discover the cause. On this note, let’s take a look at some of these triggers.

 

What Causes Leaky Gut?

 

To reiterate, there isn’t any one conclusive cause due to the shortage of research done. However, there are a number of items upon this could give rise to your intestines getting weak, ineffective, and leaky agreed. These include:

 

  • Excessive alcohol usage (which can irritate the intestinal wall)
  • A poor diet (we will talk about this more)
  • Chemotherapy
  • Gluten
  • Stress
  • Antibiotics
  • Prescription hormone medicine
  • Prescription corticosteroids (like hydrocortisone)
  • Enzyme deficiency (like having lactose-intolerance)
  • Toxic metals
  • Aspirin, ibuprofen, and other anti-inflammatory drugs
  • Chemotherapy and radiation therapy

 

Your gut has a great deal of difficult work to do. Not only does it need to digest and break it down into nutrients to nourish your body, in addition, it has to guard you from toxins which would otherwise put in your bloodstream and of the waste products. This heavy responsibility warrants that we take care of our bowels. Unfortunately, the greater bulk of people today don’t even give a second thought.

 

Your typical American diet is filled with sugary soft drinks, white flour, and otherwise high tech, low-fiber foods. This leads to an unhealthy gut in which germs are useless and weak while bacteria flourish and harm your intestines. The walls of your intestines begin to neglect when the damage is too severe. They become permeable and start to permit the toxins and waste, so which was intended to remain right into your bloodstream.

 

Some of those other items on the above list, such as alcohol and some prescription and over-the-counter medications, also have a negative effect on the internal flora of your intestines. You have a harder time fighting the things that pass through it and digesting your food if the good bacteria is killed off in your gut. Your gut can begin to leak and becomes unhealthy as the good bacteria make way for bacteria.

 

How Exactly is Leaky Gut Connected to Diabetes?

 

To provide you the most shocking news first: new study suggests that you can have each of the genetic predispositions to diabetes in the world, however you’ll never really contract diabetes unless you’ve got a leaky gut also. This means (if this study is correct) for those who have diabetes, then you already have a leaky gut.

 

The largest link between migraines, leaky gut and diabetes is inflammation. Inflammation is involved with developing type 2 diabetes. In fact, many disorders are associated with inflammation such as:

 

  • Periodontal disease
  • Stroke
  • Heart disease
  • Insulin resistance and Type 2 diabetes

 

When toxins leak from your intestines and in your bloodstream, this causes an immune response from the human body. The modest cells that your body sends out do their best to remove toxins and the bacteria from inducing damage than inflammation could ever cause. Unfortunately, that’s just what happens. The war against germs waged by your immune system induces a whole lot of inflammation.

 

Continuous abnormal inflammation (like that caused by a leaky gut) changes your natural insulin levels and actions, contributing to diabetes. You eventually form, once your body starts to become insensitive to insulin. You are able to see the cycle here. The more inflammation. The more inflammation, the insulin resistance. If you add that on top of a continuously leaky gut isn’t far off.

 

Inflammation causing insulin resistance has been observed by Mario Kratz, Ph.D., in experiments involving mice also. Some of the mice were fat, which caused a constant inflammation. Insulin resistance was developed by the mice with this inflammation. This left the question: was it that the inflammation, or Was the fat causing the insulin resistance? To answer this question, scientists bred mice that lacked the ability to generate certain immune responses that cause inflammation. Then they proceeded to feed. What was the result? These mice didn’t have insulin resistance. What does this mean? It usually means that the insulin resistance came in the inflammation, not the fat cells themselves. This supports researcher’s claims that diabetes is contributed to by inflammation caused by a leaky gut.

 

Another experiment conducted on mice in 2012 took a different approach. The mice were given a drug called Tamoxifen to simulate bad gut feature, ruin their inner ecology and kill healthy bacteria. The researchers found similarities between the bowels of mice with mice and diabetes whose guts were ruined with Tamoxifen. The two groups of mice enhanced, when given insulin. To the scientists, this demonstrated that diabetes is strongly associated with gut health.

 

To outline, scientists do not know everything about leaky gut and how it results in diabetes, but they are starting to learn more. There is certainly more research but it is apparent that an unhealthy gut doesn’t only have an effect on digestion, but can have side effects for the health of the body.

 

How Would I Know if I Have a Leaky Gut?

 

The very first thing you might do is refer back to the indicators of a leaky gut which we already laid out for you (things such as skin rashes, joint pain, nausea, chronic fatigue, and IBS), but that might not help you as much as you’d believe. The potential symptoms includes side effects of another list of distinct ailments that have nothing to do with a leaky gut.

 

Some other things you can look at would be things such as:

 

Food Sensitivity

 

When radicals are continuously leaking into your blood due to a leaky gut, your body is overproducing trigger-happy antibodies, and those antibodies start to attack things which they would not normally. This causes food sensitivity, particularly to milk and gluten.

 

Malabsorption

 

As you can imagine, people with a degenerative digestive tract that’s leaking, also have difficulty absorbing nutrients. This can become evident through side-effects like fatigue.

 

Thyroid Issues

 

Leaky gut can directly contribute to chronic thyroiditis. This also leads to slow metabolism, constipation, chronic fatigue, and depression.

 

Tests To Identify & Diagnose Leaky Gut

 

It is difficult to link some other symptom straight with leaky gut due to the fact that the symptoms might be the result of almost anything else. There are a few tests that you could do in order to see whether you’ve got it. Here are some tests which could be done to identify leaky gut:

 

Lactulose/Mannitol test

 

This test involves drinking a sugary solution. A urine sample tested and is removed. If lactulose and mannitol are present, it could suggest a leaky gut.

 

Stool Evaluation

 

An expensive test that assesses for bacteria and yeast to see if your gut is infected. This evaluation isn’t likely to be covered by your insurance.

 

What Can I do to Prevent or Cure Leaky Gut?

 

We have to keep in mind the germs that reside inside your body make up a very important ecosystem that keeps your digestive tract healthy. So let us start thinking about how we could make that job easier, or at least enjoyable your intestines have a job.

 

Since we have mentioned several times by now, leaky gut has a lot to do with your internal germs or intestine flora. Minimize bacteria and you want to maximize the amount of bacteria that are good. This may be done through diet and exercise. It sounds simple, but there is more to it in this circumstance.

 

What sort of diet do you really require?

 

When it comes to diet, it takes more than a simple “eat healthier!” Recommendation to fight an already leaky gut. You have to imagine that your bacteria is entirely dead. To counteract your useless gut flora, you ought to think about “re-seeding” it using healthy bacteria from your diet plan. You can accomplish so by eating probiotic foods like “lassi” (a noodle drink), fermented vegetables like kimchi, or other probiotic foods such as sauerkraut, miso, or kombucha (locate a listing of probiotic foods here).

 

One more thing you can do is eat naturally anti-inflammatory foods to counteract the side-effects of leaky gut. Some of those foods are things like avocados, walnuts, healthy fats (such as omega-3 fatty acids), and olive oil (find out more about anti-inflammatory foods here).

 

Once you get started ingesting foods which will combat a leaky gut such as those mentioned previously, it is time to stop eating foods that give rise to inflammation. These foods are things such as red meat, fried foods (such as french fries — sorry!) , refined carbs (think white bread), margarine, cheese (as well as other calcium-rich dairies). These foods aren’t easy in your gut flora and tend to increase inflammation in the body.

 

It would also be a good idea to avoid any trans fats, and sugary foods altogether. Refined sugar contributes. In light of diabetes, anything to help improve insulin levels and a leaky gut ought to be considered.

 

As a review, you should replace as many processed foods as possible with organic possibilities, re-seed your gut with good bacteria by eating fermented foods, and avoid foods that give rise to inflammation or insulin resistance.

 

What about supplements and medications?

 

There are particular things that may be taken orally that affect your gut flora at a positive or a negative manner that isn’t necessarily considered a portion of your diet. So let’s talk about drugs and nutritional supplements.

 

You will find nutritional supplements you may take in the kind of probiotics. This certainly can help improve your digestive tract function by maintaining a healthy gut flora. Probiotics give a large dose of one type of bacteria to you for your intestines that promote good digestion, absorption, and inflammation.

 

On the other hand, there are lots of drugs that harm your gut flora. Taking antibiotics may be necessary when you’re sick, but don’t overuse them in pill form or perhaps in antibacterial soap. Over just bacteria are killed by antibiotics, they kill the bacteria that are good as well.

 

Other substances you might encounter that you may not think about are things like chlorinated water, agricultural chemicals located on non-toxic vegetables and fruits, and traces of antibiotics located in factory-farmed meat might also harm your internal flora.

 

In Overview: Key Takeaway

 

Leaky gut definitely results in, and potentially causes diabetes alongside any number of different illnesses. Thankfully, it is avoidable and curable; thus look after your intestines. If you eat healthy, exercise, and maintain your inner flora, you will be thanked by your gut personally, and you can potentially get an upper hand or even avoid it altogether.

 

The scope of our information is limited to chiropractic and spinal injuries and conditions. To discuss options on the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .�
 

By Dr. Alex Jimenez

 

Additional Topics: Wellness

 

Overall health and wellness are essential towards maintaining the proper mental and physical balance in the body. From eating a balanced nutrition as well as exercising and participating in physical activities, to sleeping a healthy amount of time on a regular basis, following the best health and wellness tips can ultimately help maintain overall well-being. Eating plenty of fruits and vegetables can go a long way towards helping people become healthy.

 

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TRENDING TOPIC: EXTRA EXTRA: About Chiropractic

 

 

What Should You Eat To Heal a Leaky Gut?

What Should You Eat To Heal a Leaky Gut?

If you are concerned that you may have, or could develop, a leaky gut, then changing your diet to one that protects the gut is a natural next step for you.� If you are already battling health conditions related to having a leaky gut, then you will have to be more strict with your dietary choices and also address other lifestyle factors like getting good quality sleep, managing stress, finding time for low-strain exercise, and getting outside.

The first and most important thing to do to heal a leaky gut is to stop eating foods that damage and inflame the gut lining!� It can take six months or more for the gut to fully heal depending on the extent of the damage, the health of the gut microflora and your individual genetics (for people with Small Intestinal Bacterial Overgrowth, recovery can take up to two years!).� Until the gut is completely healthy, it is important to abstain from all grains, all legumes, and all dairy products (some people may tolerate ghee and/or butter from grass-fed sources, but I recommend leaving it out for at least a month before trying it).� It is also important to avoid additives in processed foods (many of which irritate the gut) and refined sugars (which promote inflammation).� Some people will also need to eliminate vegetables from the nightshade family (tomatoes, eggplants, peppers of all kinds, and especially potatoes), eliminate egg whites (I actually rinse my egg yolks before eating them), and limit nut consumption (other than coconut and macadamias).� Changing your diet to avoid gut-irritating foods is critical.� But, it is also important to include foods that can reduce inflammation and help heal the damaged gut.

Eat foods that reduce inflammation.� It�s very important to be mindful of both your omega-6 and your omega-3 polyunsaturatedfatty acid intake.� Omega-6 polyunsaturated fats, which are found in large quantities in modern vegetable oils, meat from grain-fed animals, and many nuts and seeds, increase inflammation.� Omega-3 fatty acids, which are found in large quantities in wild-caught fish, pastured/free-range eggs, and meat from pastured animals, decrease inflammation.� To help reduce overall inflammation and heal the gut, aim for a 1:1 ratio of omega-3 to omega-6 fatty acid intake in your diet.� There are several ways of doing this:� you can make sure that all of the meat in your diet is exclusively from grass-fed animals (beef, bison, goat or lamb); you can eat plenty of wild-caught seafood; and/or you can supplement with a good quality fish oil.

Vegetables are rich in anti-oxidants, vitamins and minerals which help control inflammation (and help with just about every other normal function of the body!).� Eating a variety of differently colored vegetables, a variety of dark green leafy vegetables, and a variety cruciferous vegetables (broccoli, cauliflower, cabbage, turnip greens, kale, Brussels sprouts, etc.) every day will provide all of the essential vitamins and minerals in a way that is easy for the body to absorb (no more need for a multivitamin!).� Fruits, especially berries, are also a good source of antioxidants, vitamins and minerals.� However, most people will need to exercise some portion control with fruits due to the high sugar content.� I recommend eating vegetables at every meal (it can be a bit strange getting used to eating vegetables at breakfast, but it�s amazing what a difference it makes to how you feel for the whole rest of the day!).

It is also important to make sure you are getting enough Vitamin D.� You can achieve this by simply spending some time outside in the sun every day, or from eating liver once or twice per week, or from supplementing with Cod Liver Oil or Vitamin D3 supplements.

Eat foods that restore gut microflora.� If you have a leaky and inflamed gut, chances are very good that your resident good bacteria are having trouble too.� To help restore their numbers and their diversity, eat as many different good sources of probiotics as possible.� You can do this by taking Probiotic supplements and changing brands every time you buy a bottle (the different brands all have different proprietary strains, which helps with increasing your gut microflora diversity).� Even better, you can consume probiotic rich foods, like unpasteurized Sauerkraut and other unpasteurized fermented vegetables, Kombucha Tea (my personal favorite), and coconut milk Yogurt or Kefir (which can be a little harder to find in stores but very easy to make at home).� All of these can be found at alternative grocery stores (like Whole Foods), and some can be found online, but all can also be made easily and inexpensively at home.

Eat foods that promote healing:� As the body tries to heal itself, it�s important to provide it with plenty of good quality protein (needed to make all those new cells and connective tissues) as well as vitamins, minerals and good fats.� In this way, the best way to promote healing is to eat a paleo diet that includes wild-caught fish, meat from grass-fed sources, organ meat (preferably from pastured sources), and plenty of vegetables.� There are two other healing foods that are very important to include: coconut�and bone broth.� Antimicrobial short- and medium-chain saturated fats, like those found in coconut oil�and other coconut products, help to reduce overgrowth of bad yeast, fungus and bacteria in the small intestine.� Medium chain saturated fats are very gentle on the cells that line the gut since they can be passively absorbed without being broken down by digestive enzymes and used for energy without any modification.� This source of easy energy is very helpful for healing the lining of the gut.�Broth made from the bones of chicken, turkey, duck, beef, lamb pork and/or fish are anti-microbial, anti-inflammatory, and contain nutrients which help rebuild the integrity of the digestive tract.� Most importantly, broth is rich in the amino acids proline and glycine, which help regulate digestion, reduce inflammation, and promote healing in every part of the body.

While these dietary changes may seem overwhelming, it is important to remember that making them will keep you healthy, put many diseases into remission, and prevent dozens of other diseases from developing.� For the vast majority of people, using diet to prioritize gut health will mean a lifetime of good health.

Sourced through Scoop.it from: www.thepaleomom.com

Bloating, gas and inflammation are some of the most common symptoms signaling the presence of leaky gut syndrome and it could have been caused due to improper nutritional habits. Digestive health is essential towards the overall health of the body. When a balanced diet is not being followed, the gut can struggle to absorb nutrients and water from food. For people with a leaky gut, a proper diet can help heal them from the disorder.

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Vaccines Revealed and Exposed on Episode #2

As a healthcare provider, Dr. Patrick Gentempo has been searching for the truth behind the effects of vaccines on the general population. When making critical decisions about you and your children�s health, it�s essential to have the correct knowledge of all medical procedures you�re being involved in, including the administration of mandatory vaccines, among others.

For more information, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .�