Back Clinic Natural Health Functional Medicine Team. This is a natural approach to health care. It is a natural healing practice or a branch of alternative medicine that looks at nature for answers and explanations. There are a few Western forms of alternative medicine that NCCAM has classified as Biologically Based Therapies, as well as, Mind and Body Interventions used in stress management.
There is nothing magical about it. It is about natural healing therapies for prevention and healthy lifestyles. This means eating natural whole foods, nutritional supplements, physical exercise. This is nothing new, but it has evolved over the years within certain prevention parameters, and healthy lifestyles have proven to work repeatedly. There is nothing anti-intellectual or anti-scientific about it. All health, wellness, illness, and healing can be positively affected by simple and inexpensive natural therapies.
Nutrition is considered to be one of the most well-understood environmental factors associated with changes in the epigenome. Nutrients in the foods we eat are processed by our metabolism and turned into energy. One metabolic pathway, however, is responsible for producing methyl groups or fundamental epigenetic marks that regulate our gene expression. Essential nutrients, such as B vitamins, SAM-e (S-Adenosyl methionine), and folic acid are important components in this methylation process. Diets with high amounts of these essential nutrients can quickly change gene expression, especially during early development. In the following article, we will discuss the connection between nutrition and the epigenome.
Nutrigenomics and Health
Healthcare professionals discuss that when it comes to dealing with health issues like inflammation and chronic pain, understanding how nutrigenomics affects our overall health is important. Nutritional genomics, or nutrigenomics, is a science that studies the relationship between nutrition, health, and the genome. Researchers in the nutrigenomics field believe that changes in epigenetic marks may be associated with a variety of health issues, including inflammation or the development of diseases like obesity, heart problems, and cancer. Studies have demonstrated that we may be able to control the effects of the nutrients we eat in order to change gene expression associated with various health issues.
Approximately more than 1 out of 3 adults in the United States have been diagnosed with obesity which ultimately increases the risk of a variety of health issues, including prediabetes and type 2 diabetes, among other diseases. Previous studies have demonstrated that changes in epigenetic marks during early development may even predispose individuals to obesity. Moreover, changes in epigenetic marks were also demonstrated to affect metabolic pathways that may increase the risk of prediabetes and type 2 diabetes. Healthcare professionals in the nutrigenomics field have created new ways to be able to better find balance through a wholesome understanding of nutrition and the epigenome.
“An epigenetic test can provide data that is useful for healthcare professionals. It may also offer information about how certain metabolic pathways are affected by essential nutrients, such as vitamins and minerals”.
What is the Epigenetics Diet?
The term “epigenetics diet” was first coined by Dr. Trygve Tollefsbol in 2011. It is medically defined as a group of compounds, such as resveratrol in red grapes, genistein in soybeans, isothiocyanates in broccoli, and many other well-known types of foods, which have been demonstrated to help change epigenomic marks and gene expression. According to researchers, the epigenetics diet can prevent the progression of tumors by regulating enzymes that control these epigenomic marks and gene expression, including DNA methyltransferases, histone deacetylases, and certain non-coding RNAs. Several types of foods included in the epigenetics diet are demonstrated in the following infographic:
Researchers used recently advanced technologies that demonstrated how several bioactive compounds may aggravate damage to the epigenome caused by environmental pollutions. By way of instance, dietary supplementation with methyl donors, such as vitamin B12, choline, and folate, among others, as well as the isoflavone genistein, can regulate changes to epigenome marks and gene expression caused by bisphenol A, a hormone-disrupting chemical. B vitamins may also prevent the loss of DNA methylation caused by air pollution. According to these same studies, dietary supplementation with folic acid has also been demonstrated to help prevent the negative side-effects caused by heavy metals.
We believe that foods in the epigenetics diet could be used to counteract changes to gene expression and epigenomic marks caused by environmental pollution. Environmental pollutants in several types of foods, such as pesticides in fruits like strawberries and leafy greens like spinach, bisphenol A in the plastic containers of foods and drinks, dioxins in fatty foods, polycyclic aromatic hydrocarbons produced when meat is grilled or smoked at high temperatures, and mercury in several types of seafood like king mackerel and swordfish, have been associated with changes to epigenomic marks and gene expression. Those exposures, especially during early development, may cause various health issues.
For more information regarding the connection between nutrition and the epigenome, please review this article:
Nutrition is one of the most understood environmental factors associated with changes in epigenomic marks and gene expression. Essential nutrients found in the different types of foods we eat are metabolized and turned into molecules in order to be used for energy by the human body. One metabolic pathway is responsible for creating methyl groups, important epigenetic marks that regulate our gene expression and epigenomic marks. Essential nutrients, including B vitamins, SAM-e (S-Adenosyl methionine), and folic acid are fundamental components in DNA methylation. Diets that are rich in these essential nutrients can quickly change epigenetic marks and gene expression, especially during early development. Furthermore, adding a variety of good foods to a smoothie can be a fast and easy way to add essential nutrients to your diet. Below is a fast and easy smoothie recipe to help feed your genes. – Dr. Alex Jimenez D.C., C.C.S.T. Insights
Ginger Greens Juice
Servings: 1 Cook time: 5-10 minutes
� 1 cup pineapple cubes
� 1 apples, sliced
� 1-inch knob of ginger, rinsed, peeled and chopped
� 3 cups kale, rinsed and roughly chopped or ripped
� 5 cups Swiss chard, rinsed and roughly chopped or ripped
Juice all ingredients in a high-quality juicer. Best served immediately.
Add Nasturtium to Your Smoothies
Adding nasturtium flowers and leaves to any smoothie can add extra nutrients. These lovely plants are easy to grow and the entire plant is edible. Nasturtium leaves are high in vitamin C, which is essential for a healthy immune system, and they also contain calcium, potassium, phosphorus, zinc, copper, and iron. According to healthcare professionals, the extract from the flowers and leaves have antimicrobial, antifungal, hypotensive, expectorant, and anticancer effects. Antioxidants in garden nasturtium occur due to its high content of compounds such as anthocyanins, polyphenols, and vitamin C. Due to its rich phytochemical content and unique elemental composition, the garden nasturtium may be used in the treatment of a variety of health issues, including respiratory and digestive problems. Not to mention, the flowers and leaves look absolutely lovely in smoothies.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask�Dr. Alex Jimenez�or contact us at�915-850-0900.
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
Kirkpatrick, Bailey. �Epigenetics, Nutrition, and Our Health: How What We Eat Could Affect Tags on Our DNA.� What Is Epigenetics?, What Is Epigenetics? Media, 11 May 2018, www.whatisepigenetics.com/epigenetics-nutrition-health-eat-affect-tags-dna/.
Li, Shizhao, et al. �The Epigenetics Diet: A Barrier against Environmental Pollution.� On Biology, BMC Media, 23 May 2019, blogs.biomedcentral.com/on-biology/2019/05/20/the-epigenetics-diet-a-barrier-against-environmental-pollution/.
Insulin is an essential hormone that regulates blood sugar levels. It is naturally produced in the pancreas and helps move excess glucose from the bloodstream into the cells to be used for energy. When the pancreas recognizes high blood sugar levels, it creates more insulin to reduce glucose. However, this can diminish the pancreas of insulin-producing cells which can eventually cause insulin resistance or impaired insulin sensitivity. If the pancreas can’t produce enough insulin, it can lead to prediabetes or type 2 diabetes. In the following article, we will discuss natural ways to improve insulin resistance or impaired insulin sensitivity to prevent and regulate prediabetes and type 2 diabetes, among other health issues.
Foods to Avoid with Insulin Resistance
If you have insulin resistance or impaired insulin sensitivity associated with prediabetes, type 2 diabetes, or any other health issue, there are several types of foods that can increase blood sugar levels. Frequently eating foods with high glucose content can diminish the insulin-producing cells that can ultimately affect the human body’s ability to produce enough insulin. When this occurs, high blood sugar levels remain elevated which can ultimately cause prediabetes and type 2 diabetes as well as lead to a variety of other health issues, including damage to organs such as the eyes and kidneys or limbs (neuropathy). Avoid eating the following types of foods if you have insulin resistance or impaired insulin sensitivity:
fried foods
processed snacks and foods
dairy products from cows, such as milk
foods high in saturated fats, such as butter, and salt pork
refined grains, such as white rice, pasta, bread, and flour-based foods
sugary sweets and pastries, such as ice cream, chocolate bars, and cupcakes
starchy vegetables, such as corn, potatoes and yams (without skin), and pumpkin
sweetened drinks or beverages, such as fruit juices, fountain drinks, and sodas
alcohol, such as beer and grain alcohol, in large quantities
Foods to Eat with Insulin Resistance
Many people are commonly deficient in essential nutrients, such as calcium, potassium, magnesium, and fiber. These nutrients are necessary for regulating blood sugar levels. People with insulin resistance or impaired insulin sensitivity, or any other health issue, including prediabetes or type 2 diabetes, should eat foods that have plenty of these essential nutrients. According to the American Diabetes Association, people with insulin resistance or impaired insulin sensitivity can eat from any of the basic food groups, however, it’s fundamental for individuals to understand which types of foods can increase blood glucose levels. Eat from the following types of foods if you have insulin resistance or impaired insulin sensitivity:
antioxidant-rich foods, such as berries
citrus fruits, such as oranges, lemons, and limes
non-starchy vegetables, such as dark leafy greens, peppers, and broccoli
protein-rich foods, such as legumes, nuts, soy, fish, and lean meats
high-fiber foods, including beans, and lentils
omega-3 fatty acid-rich foods, such as sardines, herring, and salmon
certain types of whole grains, such as oats, quinoa, and barley
water, especially as a substitute for sweetened drinks and
unsweetened teas
Exercise to Improve Insulin Resistance
Eating good foods and avoiding bad foods can help improve insulin resistance or impaired insulin sensitivity, however, there’s another natural way to improve this health issue: exercise. Participating and engaging in regular exercise helps improve insulin resistance or impaired insulin sensitivity associated with prediabetes and type 2 diabetes, among other health issues, by moving sugar from the bloodstream into the muscles to be used for energy. The American Heart Association recommends approximately 150 minutes of exercise every week for adults. Participating or engaging in exercise on a daily basis can improve high blood sugar levels as well as promote overall health and wellness.
For more information regarding how to naturally improve insulin resistance, please review this article:
Insulin is an essential hormone that is naturally produced in the pancreas to help regulate blood sugar levels and move excess sugar from the bloodstream into the cells to be used for energy. When the pancreas senses high blood sugar levels in the blood, it creates more insulin to help reduce glucose. However, this can decrease the amount of insulin-producing cells in the pancreas which can cause insulin resistance or impaired insulin sensitivity. If the pancreas can’t produce enough insulin, it can ultimately lead to prediabetes or type 2 diabetes, among other health issues. There are several natural ways to improve insulin resistance or impaired insulin sensitivity to prevent and regulate prediabetes and type 2 diabetes, including eating good foods, avoiding bad foods, and exercising. Furthermore, adding a variety of good foods to a smoothie can be a fast and easy way to add nutrients to your diet. – Dr. Alex Jimenez D.C., C.C.S.T. Insights
Sweet and Spicy Juice
Servings: 1 Cook time: 5-10 minutes
1 cup honeydew melons
3 cups spinach, rinsed
3 cups Swiss chard, rinsed
1 bunch cilantro (leaves and stems), rinsed
1-inch knob of ginger, rinsed, peeled, and chopped
2-3 knobs whole turmeric root (optional), rinsed, peeled, and chopped
Juice all ingredients in a high-quality juicer. Best served immediately.
Eat Mushrooms
One simple thing we can do to improve the microbiome!
Mushrooms feed bacteria in the gut. They are rich in chitin, hemicellulose, ? and ?-glucans, mannans, xylans, and galactans. They are also amazing prebiotics that promotes the growth of gut microbiota, equalling health benefits.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask�Dr. Alex Jimenez�or contact us at�915-850-0900.
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
Raman, Ryan. �14 Natural Ways to Improve Your Insulin Sensitivity.� Healthline, Healthline Media, 17 May 2017, www.healthline.com/nutrition/improve-insulin-sensitivity.
Felman, Adam. �Diet and Insulin Resistance: Foods to Eat and Diet Tips.� Medical News Today, MediLexicon International, 27 Mar. 2019, www.medicalnewstoday.com/articles/316569#foods-to-eat.
Healthcare professionals commonly give nutritional recommendations based on an entire population, only sometimes changing these according to age, sex, and pregnancy. Over the last 20 years, however, an increase in research studies has demonstrated that epigenetics can ultimately affect nutrition and even increase the risk of developing a variety of health issues, including oxidative stress and inflammation. Recent advances in technology are also currently being used to help healthcare professionals understand how nutrigenomics can affect an individual’s overall health and wellness.
Several research studies have also demonstrated that single nucleotide polymorphisms can explain the risk for individual complex disease traits. A single-nucleotide polymorphism, or SNP, is a substitution of a nucleotide that happens in the genome. Moreover, further research studies can be utilized to explain the variation in health issue risk based on nutrition and genome. The purpose of the following article is to discuss recent developments in the field of epigenetics and personalized nutrition as well as to consider the contribution of research studies to nutritional recommendations.
Understanding Nutrigenomics
Epigenetics is a collection of changes that affect chromatin structure, without altering our DNA sequence, while allowing transcriptional regulation over a range of timescales. Common epigenetic processes include histone modification, non-coding RNAs, and DNA methylation. Many research studies on how epigenetics affects personalized nutrition focus on DNA methylation, however, research findings have demonstrated other epigenetic marks. DNA methylation inside a dinucleotide is a well-known modification in the genome of a variety of mammals in DNA replication and cell division.
Methylation of dinucleotides is shown by DNA methyltransferases, or Dnmts, and is regulated by mitosis. DNA methylation can trigger transcriptional silencing by blocking and/or promoting the connection of transcription factors in the methyl CpG-binding protein MeCP2 which activates histone-modifying complexes to the DNA. MeCP2 activates what is frequently referred to as histone deacetylases, or HDACs, and histone methyltransferases, or HMTs, resulting in a closed chromatin structure and transcriptional silencing. These have been demonstrated to be associated with various health issues.
Dnmt1 is activated by HDACs and HMTs which suggests that chromatin structure may also affect the status of DNA methylation in the regulation of genes associated with nutrition. According to healthcare professionals, epigenetic marks are essentially maintained throughout an individual’s life. However, recent research findings show that epigenetic plasticity can be affected in early development, including in stages of increased physiological changes, such as puberty and aging. This ultimately suggests the possibility that epigenotypes associated with the increased risk of developing health issues can change.
Epigenetics, Personalized Nutrition, and Origins of Health Issues
Research studies have demonstrated that our early life environment can affect our epigenetic process and the origins of health issues. Healthcare professionals also believe that nutrition in our early life can affect our epigeno- and phenotype in the future. Pregnant rat groups given a diet with corn oil resulted in hypermethylation and decreased gene expression in the offspring, causing mature osteoblasts. This is the first research study to find how maternal diet affects epigenetic processes by altering morphogenesis and changing non-imprinted gene expression in pregnant rat groups.
Pregnant rat groups given a diet with an undisclosed type of fat had increased fetal blood glucose concentration and increased mRNA expression of gluconeogenic genes in the fetal liver. A recent research study found that the amount of fat in the maternal diet was one of the major factors resulting in epigenetic changes in the offspring of pregnant rat groups. The diets given to the pregnant rat groups including fat derived from safflower oil, butter, hydrogenated soybean oil, or fish oil caused hypermethylation in the offspring compared with those where pregnant rat groups were only given 7 percent fat.
Furthermore, one research study found that pregnant rat groups given a protein-restricted, or PR, diet developed epigenetic silencing in both histone modifications and DNA methylation which was followed by progressive transcriptional suppression as the offspring aged. The research findings suggest that nutrition during early development can ultimately cause long-term changes in phenotype. Pregnant rat groups given a PR diet also developed hypomethylation of specific dinucleotides in the adipose tissue leptin promoter and in the heart PPARa promoter in adult offspring.
For more information regarding how epigenetics affects personalized nutrition, please review this article:
Healthcare professionals have demonstrated that we can change gene expression and improve the risk of developing a variety of health issues, including oxidative stress and inflammation which can cause chronic pain, by controlling the food we eat. Starting in the kitchen and then taking it to the genes, if we follow a balanced nutrition, we will see a considerable change in our overall health and wellness. We have the ability to assess your specific genetic factors and what dietary guidelines are best for you to follow. One test we use is from DNA life called DNA Diet. A sample of this report is shown below:�
Research studies have demonstrated how epigenetics affect personalized nutrition. The same research studies have also demonstrated that a balanced nutrition can change our gene expression to improve how good food affects our overall health and wellness. While following a proper diet can help improve the risk of developing a variety of health issues, including oxidative stress and inflammation associated with chronic pain, eating good food may be difficult for some people. That’s why drinking smoothies or juices can be easy ways to include the balanced nutrition we need to promote our well-being. In the section below, I’ve provided a smoothie recipe so you can take your health and wellness from the kitchen to your genes. – Dr. Alex Jimenez D.C., C.C.S.T. Insights
Sea Green Smoothie
Servings: 1 Cook time: 5-10 minutes
� 1/2 cup cantaloupe, cubed
� 1/2 banana
� 1 handful of kale or spinach
� 1 handful of Swiss chard
� 1/4 avocado
� 2 teaspoons spirulina powder
� 1 cup water
� 3 or more ice cubes
Blend all ingredients in a high-speed blender until completely smooth and enjoy!
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask�Dr. Alex Jimenez�or contact us at�915-850-0900.
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
KA;, Burdge GC;Hoile SP;Lillycrop. �Epigenetics: Are There Implications for Personalised Nutrition?� Current Opinion in Clinical Nutrition and Metabolic Care, U.S. National Library of Medicine, 15 Sept. 2012, pubmed.ncbi.nlm.nih.gov/22878237/.
Grains, legumes, and beans, such as kidney beans, lima beans, black beans, soybeans, and lentils, have high amounts of lectins. Other foods with high amounts of lectins include wheat and seeds of the grass family, such as barley, buckwheat, corn, millet, oats, and rye, legumes, including peanuts, and soy, nightshade vegetables, such as peppers, eggplant, and potatoes as well as dairy products, especially those originating from grain-fed animals. In the following article, we will discuss the most harmful lectins.
Most Harmful Lectins to Avoid
Most lectins can trigger inflammation and develop what is known as “advanced glycation end-products. C-reactive protein, by way of instance, is one of many lectins found in the human body that is used as an inflammatory marker. Lectins are considered to be immunotoxic because they can stimulate a hyperimmune response. Lectins are also considered to be neurotoxic and cytotoxic because they can damage nerves and cells, ultimately causing apoptosis or cell death, among other well-known health issues.
Moreover, lectins can increase blood viscosity by attaching to red blood cells. This makes red blood cell “sticky” which can result in abnormal blood clotting. Several lectins, such as WGA, can also affect endocrine function and change gene expression. Lectins may even promote leptin resistance, ultimately increasing the risk of excess weight and obesity. These factors can increase the risk of developing other health issues. If you believe you may have any health issues caused by eating lectins, you may want to avoid:
Corn
Corn-fed meats including most meats sold in grocery stores. Avoid eating factory farmed, corn-fed meat by eating certified grass-fed meat labeled by the American Grass-fed Association.
Cashews, peanuts, and unfermented soybean products. Eat fermented varieties, such as miso, natto, tamari, and tempeh.
Milk with casein A1. Casein A2 is the normal protein found in milk from buffalo, goats, sheep and some Jersey cows. Unfortunately, most cows produce casein A1 and most store-bought milk has casein A1, even if it’s organic. Casein A1 proteins develop beta-casomorphin that can attach to beta cells in the pancreas and result in an autoimmune response. Drink raw milk from organic, grass-fed, casein A2-producing cows. Jersey cows may produce either casein A1 or A2, so make sure to check with the farmer to confirm the type of milk being produced. Avoid milk from Holsteins because they produce casein A1.
How to Make High-Lectin Foods Safe to Eat
After eliminating foods with high amounts of lectins from your diet, you can further decrease lectins in your diet by:�
Peeling and deseeding fruits and vegetables. The skin, or hull, and seeds of many fruits and vegetables have high amounts of lectins. By way of instance, you’ll want to remove the seeds from tomatoes and peppers before eating them.
Choosing white grains over brown grains. Healthcare professionals suggest that white rice is preferable over brown rice because �those who eat rice as their staple grain have always stripped the hull off brown rice before they eat it. That’s because the hull contains all the harmful lectins.� Avoid lectins by choosing organic grains and using yeast or sourdough which effectively breaks down gluten and other harmful lectins.
Sprouting grains, beans, and seeds. Sprouting deactivates lectins although there are several exceptions. Do not sprout legumes. By way of instance, lectins are actually enhanced when sprouting alfalfa.
Eating fermented foods. Fermentation effectively decreases harmful lectins. A wide variety of vegetables can be fermented, ultimately boosting their health benefits.
Using a pressure cooker. The best way to neutralize lectins when cooking is to use a pressure cooker. Healthcare professionals recommend that, �If you’re cooking with beans, tomatoes, potatoes and quinoa, the pressure cooker is your best bet however, it won’t even touch the lectins in wheat, oats, rye, barley or spelt.� Avoid slow cookers since the low cooking temperatures are insufficient to remove lectins.
Tips to Decrease Lectins in Beans and Potatoes
If you choose to eat beans, it’s important to prepare and cook them properly because eating raw or undercooked beans can be harmful towards your overall health. Phytohemagglutinin is a toxin commonly found in many varieties of beans and they are especially high in raw, red kidney beans. According to the U.S. Food and Drug Administration (FDA) eating as few as four or five raw beans may cause phytohemagglutinin toxicity. To decrease lectins in high-lectin foods, consider doing the following including:
Soaking beans in water for at least 12 hours before cooking, making sure to change the water frequently. Adding baking soda to the soaking water will further neutralize lectins in beans.
Discarding the soaking water and rinsing the beans.
Cooking for at least 15 minutes on high heat or using a pressure cooker.
Lectins in potatoes, which are a member of the nightshade family, can also be reduced by cooking, although only by 50 to 60 percent. On a positive note, however, most potatoes have digestive-resistant starch which consists of complex starch molecules that resist digestion in your small intestine. These starches slowly ferment in the large intestine where they act as prebiotics that feed healthy gut bacteria. Because of this, healthcare professionals believe that we should only limit and not eliminate lectins from our diet.
Why You Should Only Limit & Not Eliminate Lectins
Healthcare professionals believe that lectin damage is associated with glyphosate contamination. Scientists make a strong case against lectins due to their potential to be harmful to your overall health. Given the number of foods with high amounts of lectins, however, it would be almost impossible to completely eliminate them from your diet. The list of lectins found in vegetables alone is lengthy and several lectins can actually provide a variety of health benefits if these are consumed in moderation.
Many vegetables with high amounts of lectins also have polyphenols which are micronutrients with antioxidants that play a fundamental role in preventing and reducing the progression of diabetes, heart disease, cancer, and neurodegenerative conditions. Polyphenols are also considered to be prebiotics because they increase the ratio of beneficial bacteria in your gut, which is another important factor for disease prevention and weight management, among providing various other well-known health benefits.
Lectins are proteins in plant- and animal-sources that can be harmful to a person’s overall health because they can attach to cell membranes. Grains, legumes, and beans, such as kidney beans, lima beans, black beans, soybeans, and lentils, have high amounts of lectins. Other foods with high amounts of lectins include wheat and seeds of the grass family, such as barley, buckwheat, corn, millet, oats, and rye, legumes, including peanuts, and soy, nightshade vegetables, such as peppers, eggplant, and potatoes as well as dairy products, especially those originating from grain-fed animals.According to healthcare professionals, eating too many foods with high amounts of lectins can cause nerve damage, lead to cell death, and even promote inflammation while others can change blood viscosity, interrupt endocrine function, and even affect gene expression. However, healthcare professionals argue that eating some foods with lectins can be beneficial as long as these are cooked and consumed properly.�– Dr. Alex Jimenez D.C., C.C.S.T. Insight
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez D.C., C.C.S.T.
References:
1. Bulletproof.com, Revenge of the Beans
2, 9, 17, 18, 22. Precision Nutrition, All About Lectins: Here’s What You Need to Know
3. Healthline April 1, 2015
4. Authority Diet, Dietary Lectins: What Are They and Should You Be Concerned?
5, 8. My Domaine June 25, 2017
6. Krispin.com October 18, 2017
7. Gundry MD May 23, 2017
10. Carbohydrate Research February 1980; 78: 349-363
11. Critical Reviews in Biotechnology 2000; 20(4): 293-334
12. Krispin.com October 18, 2017
13. Superfoodly October 8, 2017
14, 15, 16, 19. Gundry MD May 23, 2017
20, 21. U.S. Food and Drug Administration August 20, 2015
23. Youngmeagher.com, InstaPot Review 2017
24. Today’s Dietitian September 2012; 14(9): 22
Podcast: Metabolic Syndrome Explained
Metabolic syndrome is a collection of risk factors that can ultimately increase the risk of developing a variety of health issues, including heart disease, stroke, and diabetes, among other problems. Central obesity, high blood pressure, high blood sugar, high triglycerides, and low HDL are the 5 risk factors associated with metabolic syndrome. Having at least three of the five risk factors may suggest the presence of metabolic syndrome. Dr. Alex Jimenez and Dr. Mario Ruja explain the 5 risk factors associated with metabolic syndrome, in further detail, as they recommend diet and lifestyle modification advice and guidelines to help people with metabolic syndrome improve their overall health and wellness. From eating fiber and staying hydrated to exercise and better sleep, Dr. Alex Jimenez and Dr. Mario Ruja discuss how diet and lifestyle modifications can help improve the 5 risk factors associated with metabolic syndrome to ultimately prevent the risk of developing a variety of other health issues, including heart disease, stroke, and diabetes. – Podcast Insight
Neural Zoomer Plus for Neurological Disease
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention.
Food Sensitivity for the IgG & IgA Immune Response
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with a variety of food sensitivities and intolerances. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs.
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders.
Formulas for Methylation Support
XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download
* All of the above XYMOGEN policies remain strictly in force.
Modern Integrated Medicine
The National University of Health Sciences is an institution that offers a variety of rewarding professions to attendees. Students can practice their passion for helping other people achieve overall health and wellness through the institution’s mission. The National University of Health Sciences prepares students to become leaders in the forefront of modern integrated medicine, including chiropractic care. Students have an opportunity to gain unparalleled experience at the National University of Health Sciences to help restore the natural integrity of the patient and define the future of modern integrated medicine.
If you are experiencing any of these situations, then it might be something that may be attacking your immune system. Why not try to add some beta-glucan into your diet and overall health.
Throughout the last several years, beta-glucans have been gaining much attention due to the emergence of medicinal mushrooms in Western cultures. Across the country, studies have found that beta-glucans have been ubiquitous in the health food stores due to their immunomodulatory properties and cancer-protective effects. Since edible fungi have been known as the main source for beta-glucans, surprisingly though beta-glucan can be presented in a variety of foods like oats, barley, seaweeds, and yeast. Beta-glucan can also be found in dietary supplements for the body to consume.
Beta-glucans
Beta-glucan is technically a non-starch polysaccharide, a prebiotic fiber that is formed by ?-1,3 and 1,6 glycosidic bonds. With beta-glucan, it can possess numerous health benefits depending on the molecular structure of each type of bond. Studies have shown that beta-glucans that are found in cereal grains can help lower cholesterol levels and can effectively bind serum cholesterol. Beta-glucans can even play a beneficial role in obesity, metabolic disorders, and other chronic non-communicable diseases. Since beta-glucans are a prebiotic fiber, research shows that they can play a significant role in promoting a healthy microbiome in the body. It means that beta-glucan can stimulate the growth of beneficial bacteria species, mitigating pathogenic ones, and even modulating inflammation to optimize the gut environment in the body.
Beta-glucans for Immune Support
In a 2019 study, it stated that �the relationship between immunity and nutrition is considered to be completely interconnected.� More studies have shown that beta-glucan can act on several immune receptors that can stimulate immune cell activity. This includes T-cells, macrophages, neutrophils, monocytes, natural killer (NK) cells, and dendritic cells. One of the studies showed how beta-glucans could pose modulatory effects on both the innate and adaptable branches of the immune system. One of the protein receptors is known as dectin-1; this protein receptor is on the surface of macrophages and dendritic cells.
What dectin-1 can do is that they can initiate and regulate the innate immune response by insoluble binding ?-1,3, and 1,6 glucans, plus it has become essential for controlling infections in the body. While water-soluble ?-glucan can bind to the CR3 receptors, thus triggering the adaptive immune response to the body. With ?-glucans, they can enhance phagocytosis while also triggering the release of various interleukins and cytokines, thus possessing cytotoxic anti-cancer properties. Studies have shown that TNF-?, IFN-?, and NF-??, can help to support the regulation of the T-helper cell 1 and Th-2 balance for immunological homeostasis for the body. Surprisingly in other articles, they talked about how yeast-derived ?-1,3/1,6 glucan can be delivered as an oral supplement for the winter months. The article study showed how it demonstrates its protective effects against upper respiratory tract infections in the body. The study even showed how it could reduce the upper respiratory tract infection symptoms that are already in older adults that have been infected. Another study showed that ?-glucan have cytoprotective abilities from viral infections and provide immunomodulatory properties to the body and the immune system.
With the population of many individuals, it turns out that the elderly population can benefit from the ?-glucan compound. With this compound, everyone can have a healthy immune system, especially during the cold and flu season. Having a healthy immune system is important because that way, the body can protect itself from harmful pathogens through functional medicine, healthy nutritious food, and supplements. By using these options, the body can heal itself and can dampen the effects of cold and flu symptoms.
More Research on Beta-glucan
Research studies have shown that ?-1,3 glucan from the fungal cell wall is one of the key ingredients for vaccines. The research shows as well that ?-glucan can produce robust humoral and cellular immune responses for the body when it is exposed to antigens. What is interesting is that ?-glucan is known to exert antioxidant activities in the body. With their reactive oxygen species (ROS) scavenging abilities, they can exert the antioxidants into the circulatory system and the mucosal immune system. There is a study that shows that ?-glucan in barley can possess a higher total of antioxidants significantly at a better capacity than oats and yeast. The study showed that ?-glucan could be subdivided into two groups depending on whether specific receptors are involved or not. It also stated that ?-glucan could be validated as a functional food ingredient.
Conclusion
All in all, ?-glucan is an amazing non-starch polysaccharide prebiotic fiber that has amazing properties that can help the body. ?-glucan can be found in mushrooms and a variety of other foods like seaweed and oats. This compound can help boost up the body’s immune system and can dampen any harmful pathogens effects that the body has come in contact with. This compound�s beneficial properties are amazing for anyone that consumes it and even added it to their daily diet. Some products combined with ?-glucan can support the immune system with hypoallergenic nutrients and targets amino acids.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
References:
Bacha, Umar, et al. �Nutraceutical, Anti-Inflammatory, and Immune Modulatory Effects of ?-Glucan Isolated from Yeast.� BioMed Research International, Hindawi, 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5587958/.
Chan, Godfrey Chi-Fung, et al. �The Effects of Beta-Glucan on Human Immune and Cancer Cells.� Journal of Hematology & Oncology, BioMed Central, 10 June 2009, www.ncbi.nlm.nih.gov/pmc/articles/PMC2704234/.
Fuller, Richard, et al. �Yeast-Derived ?-1,3/1,6 Glucan, Upper Respiratory Tract Infection and Innate Immunity in Older Adults.� Nutrition, Elsevier, 23 Mar. 2017, www.sciencedirect.com/science/article/abs/pii/S0899900717300539.
Jurgelewicz, Michael. �New Study Demonstrates Novel Yeast-Derived Beta-Glucan Provides Immunomodulatory Effects in Older Adults.� Designs for Health, 21 Oct. 2018, blog.designsforhealth.com/si-42214/new-study-demonstrates-zinc-supplementation-improves-clinical-outcomes-from-traumatic-brain-injury.
Levitz, Stuart M, et al. �Exploiting Fungal Cell Wall Components in Vaccines.� Seminars in Immunopathology, U.S. National Library of Medicine, Mar. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4329074/.
Nakashima, Ayaka, et al. �?-Glucan in Foods and Its Physiological Functions.� Euglena, Co., Ltd., 14 Aug. 2017.
Nakashima, Ayaka, et al. �?-Glucan in Foods and Its Physiological Functions.� Journal of Nutritional Science and Vitaminology, U.S. National Library of Medicine, 2018, www.ncbi.nlm.nih.gov/pubmed/29491277.
Team, DFH. �Modulators of Immune Health: Beta-Glucans.� Designs for Health, 26 Mar. 2020, blog.designsforhealth.com/node/1219.
Team, DFH. �Mushrooms for Nutritional Medicine.� Designs for Health, 14 Feb. 2019, blog.designsforhealth.com/node/952.
Vetvicka, Vaclav, et al. �Beta Glucan: Supplement or Drug? From Laboratory to Clinical Trials.� Molecules (Basel, Switzerland), MDPI, 30 Mar. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6479769/.
The University offers a wide variety of medical professions for functional and integrative medicine. Their goal is to inform individuals who want to make a difference in the functional medical fields with knowledgeable information that they can provide.
If you are experiencing any of these situations, then you might want to try astaxanthin.
The body needs specific vitamins, minerals, and supplements from food, in order to function correctly. The variety of these nutrients can be found in healthy foods like fruits, vegetables, lean meats, and whole grains are precisely what the body needs. One of the essential nutrients that the body needs is antioxidants. Antioxidants help the body get rid of free radicals that can cause the body to become overly stressed and leading it to develop chronic illnesses. There is an antioxidant that can help the body and can be found in berries and pomegranates, and it is called astaxanthin.
Astaxanthin
Astaxanthin is a xanthophyll carotenoid that can be found in various microorganisms and marine animals. Astaxanthin is common for humans to apply and consume into the body while also being different. This red, fat-soluble pigment is quite different from the other kinds of food that contain carotenoids. Astaxanthin surprising does not contain vitamin A like all the other food containing carotenoids, and astaxanthin is an impressive antioxidant. Studies have shown that astaxanthin can not only be beneficial for the eyes but can provide nutritional support as well as having potential health-promoting effects in preventing and treating various diseases that can harm the body. Some of the various diseases that can harm the body when there is an excessive amount of free radicals can include:
Various cancers
Chronic inflammatory diseases
Metabolic syndrome
Diabetes
Gastrointestinal diseases
Another study found that astaxanthin was superior to fish oil due to astaxanthin having the ability to enhance the body’s immune response and thus lowering the risk of vascular and infectious diseases that can harm the body, causing it to dysfunction.
A Powerful Antioxidant
There are some fantastic beneficial properties that astaxanthin can provide for the body and help improve the body�s systems as well.
Astaxanthin is a powerful antioxidant since various chronic diseases are rooted in a disproportionate balance of reactive oxygen and nitrogen species to antioxidants. Studies have shown�that astaxanthin has been known to scavenge free radicals more effectively out of the body than beta-carotene. There was another study showing how the body�s DNA was damage due to low plasma 8 -OHdG (8-hydroxy-2′-deoxyguanosine) levels.
Boosts the Immune System
The publication of the immunomodulatory effects of astaxanthin is not getting enough attention as they should be. A test study has reported that dietary astaxanthin was able to stimulate mitogen-induced lymphocyte proliferation. This will help increase the natural killer cell cytotoxicity and even delay the hypersensitivity response in the body while also increasing the numbers of total T and B cells in the peripheral blood in the body. Another study showed how astaxanthin could help significantly enhanced lymphocyte proliferation in vitro and ex vivo. The studies also found that astaxanthin can be consumed in high concentrations without the risk of cytotoxicity.
Controls Glucose and Lipids
Surprisingly there has been new research that has been revealing about another unique but vital role that astaxanthin has. The studies show that it can modulate peroxisome proliferator-activated receptors or PPARs. What this function does is that it may have various applications in human health, including producing glucose and lipid homeostasis. Since PPARs are members of the nuclear hormone receptors in the body, they are a superfamily that plays roles in the expression of many genes that are regulating cellular differentiation and many other functions in the body.
There are at least three subtypes of PPARs that helps the major organs and help the metabolism of glucose and lipids. PPAR? can primarily be expressed in the liver, kidney, heart, and skeletal muscle, where it can be involved in lipid metabolism and insulin sensitivity to the body. Another subtype of PPARs is PPAR?, which plays a role in glucose and lipid homeostasis but also is the site of action in the adipose tissue in the body. When astaxanthin is being involved, astaxanthin is a PPAR? agonist but can act as either an agonist or antagonist to PPAR? receptors. Studies have found that PPAR? agonist and PPAR? antagonist in astaxanthin can decrease cholesterol and triglycerides in loaded HepG2 cells, while changing several enzymes expressions that are being involved in lipid and glucose metabolism pathways, thus resulting in a hypolipidemic effect in the body.
Exercise Enhancement
Surprisingly astaxanthin can be used to prevent exercise-induced free radical production and is a lesser-known application. Astaxanthin can enhance exercise performance and even improve the recovery process. The increase in the reactive oxygen and nitrogen species or RONS are being produced during an exercise regime is deleterious to the health. It is often combated with a matching increase in the endogenous antioxidant enzymes. However, when a person is doing excessive exercises, it can cause RONS to rise above the body’s natural capacity to eliminate them. This will cause an increased risk of oxidative damage in lipids, protein, and DNA molecules. In a review study, it showed the ability of astaxanthin to squelch the RONS generating during exercising. It reported that the antioxidant effects of astaxanthin could provide a variety of benefits to athletes.
Conclusion
Astaxanthin is a powerful immunomodulatory antioxidant that can support numerous biological pathways that are in the body. It can dampen the effects of a variety of chronic diseases and illnesses that can harm the body. Astaxanthin is useful for being a therapeutic and powerful nutraceutical while also being an excellent addition for someone who needs supplements to support their general health and well-being. Some of the products here are beneficial to the body as they help support the immune system while providing more excellent stability.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
References:
Ambati, Ranga Rao, et al. �Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications–a Review.� Marine Drugs, MDPI, 7 Jan. 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC3917265/.
Brown, Daniel R, et al. �Astaxanthin in Exercise Metabolism, Performance and Recovery: A Review.� Frontiers in Nutrition, Frontiers Media S.A., 18 Jan. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5778137/.
Brown, Daniel R, et al. �Astaxanthin in Exercise Metabolism, Performance and Recovery: A Review.� Frontiers in Nutrition, Frontiers Media S.A., 18 Jan. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5778137/.
Choi, Chang-Ik. �Astaxanthin as a Peroxisome Proliferator-Activated Receptor (PPAR) Modulator: Its Therapeutic Implications.� Marine Drugs, MDPI, 23 Apr. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6521084/.
Lin, Kuan-Hung, et al. �Astaxanthin, a Carotenoid, Stimulates Immune Responses by Enhancing IFN-? and IL-2 Secretion in Primary Cultured Lymphocytes in Vitro and Ex Vivo.� International Journal of Molecular Sciences, MDPI, 29 Dec. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4730289/.
Park, Jean Soon, et al. �Astaxanthin Decreased Oxidative Stress and Inflammation and Enhanced Immune Response in Humans.� Nutrition & Metabolism, BioMed Central, 5 Mar. 2010, www.ncbi.nlm.nih.gov/pmc/articles/PMC2845588/?report=reader.
Team, DFH. �Applications of the Antioxidant, Astaxanthin.� Designs for Health, 27 June 2019, blog.designsforhealth.com/node/1047.
Yuan, Jian-Ping, et al. �Potential Health-Promoting Effects of Astaxanthin: a High-Value Carotenoid Mostly from Microalgae.� Molecular Nutrition & Food Research, U.S. National Library of Medicine, Jan. 2011, www.ncbi.nlm.nih.gov/pubmed/21207519.
The University offers a wide variety of medical professions for functional and integrative medicine. Their goal is to inform individuals who want to make a difference in the functional medical fields with knowledgeable information that they can provide.
If there is one thing we are learning more and more about, it is that everything can be related back to inflammation and what we put inside our bodies. Point blank. The food you consume affects your genetics and your inflammatory response in the body. Headaches, achy joints, and overall fatigue have been directly linked to inflammation.
Inflammation
Inflammation was once thought to just be something that occurs when the body has an infection or we hurt ourselves as the body’s natural response. That fact is still true to this day. However, we now know more. Now, we are able to recognize inflammation occurring inside our organs and down to the cellular level.
Just as you roll your ankle and it becomes inflamed, if you eat the wrong foods your gut becomes inflamed. This can then be traced back to leaky gut and in some cases, autoimmune diseases.
So what can we do about it? What is actually happening in our bodies?
The human body is an amazing machine that we are still finding more about each and every day. Let’s first take a look at where this inflammation is coming from. Inflammation can enter the gut barrier as a toxin, protein, pathogen, LPS, or alcohol.
If our body is continuously exposed to these triggers, it can result in our immune system becoming dysregulated. Now that our body has these triggers, things like allergies, asthma, autoimmunity, and poor immune tolerance and regulation become our bodies new regular.
Amplifying Loop
These triggers then signal something called cytokines. Cytokines are tiny and dance around inside of the cell. These cytokines increase NF-kB activity.
NF-kB is then used to transcribe DNA and express an inflammatory state!
Now, our bodies are promoting inflammation, all because we let the toxins in. What we put into our mouth and our bodies matter. The foods we eat have the ability to provide nutrients to our cells, rather than facilitating in this ongoing inflammatory response chain.
How Do I Regain Control?
Nrf2 is a key protein in the body that has the function of regulating the genome. This helps the body balance gene expressions and the regulation of our genes. Another thing Nrf2 does is upregulate genes that encode antioxidant enzymes and antiinflammatory genes.
Essentially, Nrf2 helps to fight off inflammation and reduce oxidative stress. Nrf2 activity is part of the detoxification system our bodies naturally have. It helps us to not get sick from every single bacteria we come into contact with. However, Nrf2 is a pathway, not a supplement. So now the question becomes, How do we active Nrf2?
From The Kitchen to The Genes
As mentioned earlier, everything can be traced back to the kitchen and what we put into our mouth to nourish our body. A great way to ensure you are feeding your body what it needs is to make a smoothie in the morning. Smoothies can contain so many nutrient-dense foods to aid in Nfr2 activation.
First, start off with flaxseed in the blender. Blend it up so the flax seeds get broken up and open. Next, add in blueberries, raspberries, strawberries, acai berry powder, broccoli sprouts, and almond milk!
By providing your body and your cells with the nourishment they need, they will flourish. In addition to a smoothie, there are supplements that can aid in Nrf2 activation as well. These supplements include curcumin, fish oil, wormwood, and CoQ10.
It’s clear that the “American Diet” has been causing problems for us. The world is so busy and fast-paced that we are not taking the time or giving our bodies the consideration to shop and make nutritious home-cooked meals. We need to increase our vegetables, fruits, fibers, whole grains and decrease the carbs. Everyone has some degree of inflammation in their body, and many of us do not even realize it! I challenge us to give up fast food for an entire month, cut the soda, increase the lemon water and eat at least one salad a day during this month. By increasing our vegetables and creating plates that are more colorful, our bodies will thank us! – Kenna Vaughn, Senior Health Coach�
References:
Gordon, Jacob. �Recipes for NRF2 – MyBioHack: Unlock Your Maximum Potential.� MyBioHack, MyBioHack | Unlock Your Maximum Potential, 7 Nov. 2017, mybiohack.com/blog/recipes-for-nrf2.
Gordon, Jacob. �Why NRF2 Activation Can Make You More Sick – MyBioHack: Unlock Your Maximum Potential.� MyBioHack, MyBioHack | Unlock Your Maximum Potential, 2 Feb. 2020, mybiohack.com/blog/nrf2-cirs-sensitivities.
Lawrence, T. �The Nuclear Factor NF-�B Pathway in Inflammation.� Cold Spring Harbor Perspectives in Biology, vol. 1, no. 6, 2009, doi:10.1101/cshperspect.a001651.
Ma, Qiang. �Role of Nrf2 in Oxidative Stress and Toxicity.� Annual Review of Pharmacology and Toxicology, vol. 53, no. 1, 2013, pp. 401�426., doi:10.1146/annurev-pharmtox-011112-140320.
The scope of our information is limited to chiropractic, musculoskeletal,and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at915-850-0900.
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