Back Clinic Health Team. The level of functional and metabolic efficiency of a living organism. In humans, it is the ability of individuals or communities to adapt and self-manage when facing physical, mental, psychological, and social changes in an environment. Dr.Alex Jimenez D.C., C.C.S.T, a clinical pain doctor who uses cutting-edge therapies and rehabilitation procedures focused on total health, strength training, and complete conditioning. We take a global functional fitness treatment approach to regain complete functional health.
Dr. Jimenez presents articles both from his own experience and from a variety of sources that pertain to a healthy lifestyle or general health issues. I have spent over 30+ years researching and testing methods with thousands of patients and understand what truly works. We strive to create fitness and better the body through researched methods and total health programs.
These programs and methods are natural and use the body’s own ability to achieve improvement goals, rather than introducing harmful chemicals, controversial hormone replacement, surgery, or addictive drugs. As a result, individuals live a fulfilled life with more energy, a positive attitude, better sleep, less pain, proper body weight, and education on maintaining this way of life.
If you are feeling any of these situations, then you might be experiencing low levels of glutathione, why not add some S-acetyl glutathione into your body.
Glutathione
When glutathione is decreased in the body, it is known as glutathione deficiency or GSH. It is a tripeptide that is consist of L-glutamine, L-cysteine, and glycine while also being functional in the systems of the body. The biosynthesis of glutathione can be affected by some factors such as biochemical individuality or dietary factors. Another factor that can affect glutathione in the body is chronic oxidative stress. Chronic oxidative stress can deplete cellular glutathione in the body, causing it to develop inflammation and dysfunction to its organ systems.
There are ways to boost glutathione levels in the body since these nutrients and supplements are the precursors to glutathione. They consist of whey protein, vitamin C, and glutamine, and they can help raise the glutathione levels in the body to prevent inflammation and disruptive factors that can cause harm to the body; however, the results are inconsistent and need further research. Studies stated that biological individuality is different to every type of body since it is equivalent and can metabolize the precursor nutrients and supplements to the body.
Why Not Distribute Pure Glutathione?
Sadly though, when a person takes glutathione in an oral form, the results are unpleasant. When the person takes glutathione in the mouth, the oral dosage is oxidized instantly, before being absorbed into the body, thus leaving a foul smell. Taking glutathione in a vegetable capsule can help the individual receive glutathione without it being oxidized.
Many formulas can deliver a unique preparation to glutathione that can overcome the limitations it faces. Studies show that S-acetyl glutathione is stable enough to go through the intestinal walls and deposit the necessary nutrients into the body. With S-acetyl glutathione being consumed orally, it can increase the total glutathione and the percent-reduced glutathione so it can be beneficial for the body. With percent-reduced glutathione, it has a very significant biomarker for excellent status for a functional body.
The Mechanics of SAG Absorption
S-acetyl glutathione or SAG is a lipid-like compound that is taken by intact chylomicrons in the gut. The bond from this compound is placed into its thiol group that helps prevents oxidations in the body and allows molecules to pass into the cell walls after being absorbed into the gut. What happens is that the bond is cleaved by non-specific enzymes and helps prevent the breakdown of glutathione, while S-acetyl glutathione does not need expenditures to be cleaved once it crosses the cell walls in the body.
SAG Antioxidant Activity
Since glutathione helps tissue and organ functions throughout the body, it plays a critical role by protecting it from a variety of factors like, for example, oxidative stress, while also maintain cellular functions and supporting a healthy immune system. Studies show that many factors can increase oxidative stress exposure and adding insults to the body, therefore increasing the cellular consumption of the nutrients like glutathione, which provides antioxidant activity. When this happens, it leads to the result of a fiery cycle of oxidative stress and challenges detoxification to the body. Research states that complete biotransformation and protecting the body from oxidative stress is essential for the body to maintain cellular integrity and tissue health.
Benefits of Maintaining Healthy Glutathione Levels
There is plenty of information that is related to cellular health that has been surfaced. Research states that the mitochondria, which is the energy-producing powerhouse cell, has a role in being the primary functional cellular site for consuming oxygen and ROS (reactive oxygen species).� Studies show that S-acetyl glutathione can cross the membranes of the mitochondria by increasing the organ’s activity and minimizing ROS in the body. When ROS is reduced in the body, it can maintain the mitochondrial integrity and its function, while improving its health for the body to function correctly.
Studies show that S-acetyl glutathione can decrease TNF-alpha, NF-kappa beta, and F-2 isoprostane enzymes in the body. Additional studies show that there is a large amount of evidence that intracellular glutathione levels in macrophages can influence the Th1/Th2 cytokine pattern and can help promote a well-balanced immune reaction to the body.
Conclusion
Glutathione is an essential amino acid that is produced in the body. When there are low levels of glutathione in the body, S-acetyl glutathione can assist in maintaining those levels and by making sure that oxidative stress does not reach full capacity in the body to cause significant damage. Some products can provide more excellent stability, bioavailability, and digestive comfort for anyone who might be sensitive to N-acetyl L-cysteine.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
References:
Anderson, Michelle F, et al. �Glutathione Monoethylester Prevents Mitochondrial Glutathione Depletion during Focal Cerebral Ischemia.� Neurochemistry International, Pergamon, 20 June 2003, www.sciencedirect.com/science/article/abs/pii/S0197018603001335?via%3Dihub.
Ballatori, Nazzareno, et al. �Glutathione Dysregulation and the Etiology and Progression of Human Diseases.� Biological Chemistry, U.S. National Library of Medicine, Mar. 2009, www.ncbi.nlm.nih.gov/pmc/articles/PMC2756154/.
Fraternale, A., et al. �Antiviral and Immunomodulatory Properties of New Pro-Glutathione (GSH) Molecules.� Www.eurekaselect.com, 31 May, 2006, www.eurekaselect.com/56205/article.
Kretzschmar, M. �Regulation of Hepatic Glutathione Metabolism and Its Role in Hepatotoxicity.� Experimental and Toxicologic Pathology, Urban & Fischer, 3 Nov. 2011, www.sciencedirect.com/science/article/abs/pii/S0940299396800546?via%3Dihub.
Locigno, Roberto, et al. �S-Acetyl-Glutathione Selectively Induces Apoptosis in Human Lymphoma Cells through a GSH-Independent Mechanism.� International Journal of Oncology, U.S. National Library of Medicine, Jan. 2002, www.ncbi.nlm.nih.gov/pubmed/11743644.
Lomaestro, Ben M, and Margaret Malone. �Glutathione in Health and Disease: Pharmacotherapeutic Issues – Ben M Lomaestro, Margaret Malone, 1995.� SAGE Journals, 1 Dec. 1995, journals.sagepub.com/doi/10.1177/106002809502901213.
Richman, PG, and A Meister. “Regulation of Gamma-Glutamyl-Cysteine Synthetase by Nonallosteric Feedback Inhibition by Glutathione.� The Journal of Biological Chemistry, U.S. National Library of Medicine, 25 Feb. 1975, www.ncbi.nlm.nih.gov/pubmed/1112810.
Vogel, Jens-Uwe, et al. �Effects of S-Acetylglutathione in Cell and Animal Model of Herpes Simplex Virus Type 1 Infection.� SpringerLink, Springer-Verlag, 18 Nov. 2003, link.springer.com/article/10.1007%2Fs00430-003-0212-z.
Scientists and healthcare professionals are starting to shine a light on the importance of the composition of our gut microbiome, or the population of “healthy” bacteria in our gastrointestinal (GI) tract. According to research studies, abnormal or excess amounts of gut bacteria can be one of the most common causes of a variety of digestive health issues, including SIBO and IBS. Our ancestors have included fermented foods like yogurt, kimchi, and sauerkraut as an important part of their traditional diet to regulate and manage the composition of their “healthy” bacteria: the gut microbiome. �
Finding ways to naturally improve our digestive health by maintaining a “healthy” probiotic profile has been a popular topic for many generations. As a result, eating fermented foods like those previously listed above, including other food groups with additional probiotics, and taking probiotic supplements has tremendously increased in popularity in recent years. Another way to naturally improve digestive health that has recently become more popular is fasting, strategic abstinence or reduction from several or all foods for a certain period of time. Fasting can ultimately help improve overall digestive health. �
Fasting can help support the healthy composition of our gut microbiome and it can be used as a treatment approach for a variety of conditions and diseases, such as headaches, migraines, eczema, metabolic syndrome, and obesity. Scientists and healthcare professionals have determined that fasting can stress the human body in a beneficial way. This stress benefits the healthy bacteria in the gastrointestinal (GI) tract because it helps activate autophagy or the natural cellular detoxification process. In the following article, we will discuss how fasting and autophagy can promote digestive health. �
Fasting and Autophagy Overview
Our gastrointestinal (GI) tract can often have a difficult job trying to repair our cells while sweeping undigested debris away to eliminate as waste because many people are constantly eating throughout the entire day. Many people are completely against the idea of fasting, or willingly skipping one or two meals per day, despite its benefits towards our digestive health. Because there are a variety of different methods and techniques for fasting, many people can follow this strategic way of eating and still take advantage of all its digestive health benefits. Fasting, however, may ultimately not be for everyone. �
Historically, many religious and spiritual practices used fasting as an important element in their culture to promote overall digestive health. There are currently a wide variety of fasting methods and techniques that are used to support natural well-being. Moreover, the treatment benefits of fasting are now being readily recognized in numerous research studies. The different types of fasting can ultimately vary from eating very little or nothing for a certain amount of time to drinking only water for a specific period of time, occasionally for up to five days, as a way to naturally improve digestive health. �
Intermittent fasting, a strategic way of eating that follows switching between unrestricted eating and restricted eating for a certain period of time, is one of the most common and practical fasting approaches for everyone. Scientists consider intermittent fasting to be safe and effective because you only go without eating any food for short periods of time. Research studies have demonstrated that using intermittent fasting for a total of 16 hours every day is enough to create the caloric restriction necessary to experience the benefits of fasting as well as to activate autophagy to help restore digestive health. �
The 5:2 diet is the strategic way of eating where a person consumes an average diet for five days and then greatly reduces their consumption of food to one-quarter of that of their normal diet for the other two days of the week. Every fasting approach is different but the purpose of abstinence or reduction from foods is to give our gut microbiome a break from digestion so they can focus on repairing our cells while sweeping undigested debris and excess bacteria away to eliminate as waste. Research studies suggest that the 16:8 diet may be the simplest fasting method or technique for people to follow. �
How Fasting and Autophagy Support Digestive Health
Our pancreas commonly triggers the release of glucagon when we have low blood glucose while the release of insulin is triggered to help reduce high blood glucose levels. Insulin decreases and glucagon increases during fasting which has been demonstrated to help promote improved metabolism as well as provide energy, mood changes, and weight loss. Fasting also helps promote the “healthy” composition of our gut microbiome or the population of “healthy” bacteria in our gastrointestinal (GI) tract. Scientists have associated fasting with the activation of the gene that supports overall digestive health. �
Optimal digestive health and “healthy” gut bacteria are important to help protect us from abnormal or excess bacteria, toxins, and other compounds that can trigger the immune system. Finally, fasting can help restore the integrity of the intestinal lining by managing inflammation that can ultimately help protect the human body against the variety of conditions and diseases associated with inflammation. The main benefit of fasting is that it can increase autophagy or the natural cellular detoxification process. With fasting, your gut health improves and you reduce your risk for a variety of digestive health issues. �
Fasting is a well-known, strategical way of eating which can have a variety of digestive health benefits for many people. Many people can tremendously benefit from fasting. Fasting can activate autophagy, or the natural cellular detoxification process, to help sweep excess bacteria and undigested food debris away for elimination as waste, also activating anti-inflammatory processes to reduce inflammation and oxidative stress. However, it’s important to keep in mind that fasting may not be for everyone. Make sure to talk to a qualified and experienced doctor before attempting any fasting approaches. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez �
References:
�The Impact of Fasting on Your Microbiome.� Naomi Whittel, 12 Mar. 2019, www.naomiwhittel.com/the-impact-of-fasting-on-your-microbiome/.
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �
Neural Zoomer Plus for Neurological Disease
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Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �
Food Sensitivity for the IgG & IgA Immune Response
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Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �
Formulas for Methylation Support
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XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
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For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download �
* All of the above XYMOGEN policies remain strictly in force. �
If you are experiencing any of these situations, then you might have suffered from glutathione deficiency, why not trying some NAC supplements.
NAC and Its Benefits
NAC or N-Acetyl Cysteine is an amazing semi-essential amino acid. This amino acid can be produced from the body through other amino acids like methionine and serine. It can only become an essential amino acid when dietary intake of methionine and serine are low in the body. When a person is trying to incorporate NAC in their diet, it can be found in high protein foods like meats, dairies, and legumes. Studies show that consuming NAC is essential for a variety of health reasons, especially replenishing the most potent antioxidant, glutathione in the body.
Since NAC is a nutritional supplement that is exceedingly powerful, it can help glutathione be elevated in biosynthesis. NAC is recognized for supporting average mucous production, respiratory function, and eye health positively. Research shows that NAC can protect cell and tissue health from chronic illnesses and providing support for a healthy mental status in the body. There is even more research on NAC supplements, especially when someone increases their intake on the supplement. When there is an increase in NAC, and when it is consumed in the body, the effects are astounding. The NAC supplements can help the body boost the levels of some of the neurotransmitters and improving mental health.
In a 2011 study, researchers found that NAC is emerging to be a useful agent to help treat psychiatric disorders. The results of using NAC supplements to treat psychiatric disorders has helped alleviate some of these symptoms:
Addiction
Compulsive and grooming disorders
Schizophrenia
Bipolar disorders
Alzheimer�s disease
Since NAC can exert beneficial effects on the body, this supplement is useful to provide antioxidant, neuropathy, and anti-inflammatory properties to make sure that the body is functioning. Studies show that NAC can improve the outcomes of reducing lipopolysaccharides inflammation and preventing oxidative stress from being overexposed.
With NAC being a sulfur-containing derivative for the amino acid L-cysteine, this supplement provides supportive antioxidants and detoxification mechanisms for the body. Studies show that NAC can support the body�s antioxidant activity by neutralizing highly reactive hydroxyl radicals and serving as a source to sulfhydryl groups. They are thus enhancing the production or tripeptide glutathione in the body since it is a crucial component for antioxidant and detoxification enzymes.
Glutathione
Glutathione is a powerful antioxidant that has recently gained attention for its fantastic health benefits. This powerful antioxidant is found in every cell in the human body and can be absorbed in oral form. Research shows that even though the absorption of oral glutathione may be limited, the NAC supplementation can significantly increase the circulating levels of glutathione in the body. Studies stated that individuals who are infected with HIV, have glutathione deficiency in their system and have been associated with an impaired T-cell function and survival. So taking NAC orally can be used to replenish glutathione deficiency and is useful in the HIV infection.
Another study showed that taking NAC orally can help improve the responses of patients with chronic lung disease (CLD), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF). The beneficial effects of taking NAC orally shows a decrease of inflammation in the lungs, improving the lung function, and reducing the neutrophil burden in cystic fibrosis airways.
Once this is done, though, NAC can help promote the production of glutathione and incorporate it into the crucial antioxidant enzymes and detoxification enzymes. With these enzyme activities being in play in the body, the glutathione is helping out by directly supporting their activities and the metabolism breakdown. Glutathione can also participate in fatty acid synthesis and can transport across the cell membrane.
Glutathione Factors
There are a variety of factors that can determine the requirements that glutathione can provide for the body. Glutathione can help control the toxin level exposure, increase the detoxification, and provide the overall needed support for antioxidants. Studies show that maintaining glutathione levels are essential to maintain the necessary health of the respiratory, hepatic, and the immune system from inflammation.
Research shows that since glutathione has multiple metabolic actions, they are essential for cellular homeostasis. Since it plays an important role, diseases like HIV, oxidative stress, chronic lung disease, and COPD can lower the body’s glutathione. The best way to make sure that individuals who have any chronic diseases, take NAC orally to prevent glutathione deficiency.
Glutathione can even help support antioxidant protection for lipids and proteins for the body as well as helping to maintain the standard response of inflammation due to injury. Studies show that elderly adults have altered their cellular redox levels and their dysregulated immune responses. Researchers also found out that the progression of chronic degenerative diseases of aging and that glutathione decreases with age naturally.
Conclusion
NAC is a semi-essential amino acid that has outstanding properties for the body. It helps replenishes the body�s glutathione and alleviate the symptoms caused by chronic illnesses. Taking NAC supplements is highly essential since it helps maintain adequate levels of glutathione to support overall health and well-being in the body. Some products help support glutathione levels as well as working well with NAC supplements by providing more excellent stability, bioavailability, and digestive comfort.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
References:
Atkuri, Kondala R, et al. �N-Acetylcysteine–a Safe Antidote for Cysteine/Glutathione Deficiency.� Current Opinion in Pharmacology, U.S. National Library of Medicine, Aug. 2007, www.ncbi.nlm.nih.gov/pmc/articles/PMC4540061/.
Dean, Olivia, et al. �N-Acetylcysteine in Psychiatry: Current Therapeutic Evidence and Potential Mechanisms of Action.� Journal of Psychiatry & Neuroscience : JPN, Canadian Medical Association, Mar. 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3044191/.
Favier, A., et al. �Antioxidant Status and Lipid Peroxidation in Patients Infected with HIV.� Chemico-Biological Interactions, Elsevier, 23 Jan. 2003, www.sciencedirect.com/science/article/abs/pii/000927979490037X?via%3Dihub.
Grandjean, EM, et al. “Efficacy of Oral Long-Term N-Acetylcysteine in Chronic Bronchopulmonary Disease: a Meta-Analysis of Published Double-Blind, Placebo-Controlled Clinical Trials.” Clinical Therapeutics, Centre for Reviews and Dissemination (UK), Feb. 2000, www.ncbi.nlm.nih.gov/pubmed/10743980.
Hu, Heng-long, et al. �Antioxidants May Contribute in the Fight against Ageing: an in Vitro Model.� Mechanisms of Ageing and Development, Elsevier, 26 Jan. 2001, www.sciencedirect.com/science/article/abs/pii/S0047637400002128?via%3Dihub.
Keogh, Julian P., et al. �Cytotoxicity of Heavy Metals in the Human Small Intestinal Epithelial Cell Line I?407: The Role of Glutathione.� Taylor & Francis, 20 Oct. 2009, www.tandfonline.com/doi/abs/10.1080/15287399409531926.
Nakamura, Hajime, et al. �Redox Imbalance and Its Control in HIV Infection.� Mary Ann Liebert, Inc., Publishers, 5 July 2004, www.liebertpub.com/doi/10.1089/15230860260196245.
Nall, Rachel. �NAC: Use, Benefits, and Side Effects.� Medical News Today, MediLexicon International, 4 Dec. 2019, www.medicalnewstoday.com/articles/327219.php.
Ottenw�lder, H., and P. Simon. “Differential Effect of N-Acetylcysteine on Excretion of the Metals Hg, Cd, Pb, and Au.” SpringerLink, Springer-Verlag, July 1987, link.springer.com/article/10.1007/BF00295763.
Pace, Gary W., and Cynthia D. Leaf. �The Role of Oxidative Stress in HIV Disease.� Free Radical Biology and Medicine, Pergamon, 14 Jan. 2000, www.sciencedirect.com/science/article/abs/pii/0891584995000472?via%3Dihub.
Roberts, Robert L., et al. �N -Acetylcysteine Enhances Antibody-Dependent Cellular Cytotoxicity in Neutrophils and Mononuclear Cells from Healthy Adults and Human Immunodeficiency Virus-Infected Patients.� OUP Academic, Oxford University Press, 1 Dec. 1995, academic.oup.com/jid/article-abstract/172/6/1492/820544?redirectedFrom=fulltext.
Rosa, De, et al. �N?Acetylcysteine Replenishes Glutathione in HIV Infection.� Wiley Online Library, John Wiley & Sons, Ltd (10.1111), 24 Dec. 2001, onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2362.2000.00736.x.
White, Alexander C., et al. �Glutathione Deficiency in Human Disease.� The Journal of Nutritional Biochemistry, Elsevier, 17 Jan. 2003, www.sciencedirect.com/science/article/abs/pii/0955286394900396.
Witschi, A., et al. �The Systemic Availability of Oral Glutathione.� SpringerLink, Springer-Verlag, Dec. 1992, link.springer.com/article/10.1007%2FBF02284971.
Yal�in, Elvan, et al. �N-Acetylcysteine in Chronic Blepharitis.� Cornea, 1 Mar. 2002, insights.ovid.com/crossref?an=00003226-200203000-00007.
For many people, fasting, or the concept of willingly skipping meals for a specific period of time, may not seem like a very appealing way to improve digestive health. Because most people also eat about 3 meals a day, skipping one or two meals a day can ultimately cause them to feel moody, tired, and fatigued. However, for people with digestive health issues, such as SIBO, IBS, or leaky gut, they may already be feeling these symptoms, even after eating their 3 meals a day. In this article, we will discuss how fasting can be beneficial for some patients and how it can help improve their digestive health. �
Understanding the Digestive System
The digestive system starts the process of breaking down food from the moment we eat in order to absorb nutrients, such as vitamins and minerals. The digestive system will use approximately 25 percent of the calories we consume to even start the process of digestion. Digesting food requires tremendous effort from the human body because it alters many of its main functions and pulls many resources away from other structures to simply perform it. The immune system also activates every time we eat food in order to protect the gastrointestinal, or GI, tract from anything and everything that passes through. �
When fasting, however, the digestive system can start to heal and restore the human body. During a fast, the human body will utilize fat instead of sugar as the main source of energy fuel. An average person only has about 2,500 Kcal of glycogen to use as glucose for energy while the average person has about 100,000 Kcal of fat for energy. Moreover, it may take time for the human body to become adjusted to utilizing fat instead of sugar as the main source of energy fuel, which is why many people may not feel well until several days after they’ve started fasting. Fasting can also ultimately have other benefits. �
Inflammation
Inflammation is one of the main causes of a variety of chronic conditions and diseases, including digestive health issues. According to researchers and healthcare professionals, inflammation is the common cause of SIBO, small intestinal bacterial overgrowth, IBS, inflammatory bowel syndrome, and leaky gut. Environmental factors, such as toxins, processed foods, drugs and/or medications, alcohol, and food sensitivities or intolerances can all cause inflammation. Furthermore, stress can also cause inflammation and it can tremendously affect the process of digestion and overall digestive health. �
No food will ultimately pass through the gastrointestinal, or GI, tract during a fast. With the exception of water, fasting reduces the consumption of inflammatory compounds, further reducing inflammation in the human body. Anti-inflammatory cytokines become activated while pro-inflammatory cytokines become less active when fasting. The digestive system knows when we aren’t eating and it’ll ultimately trigger these structural and functional changes. Inflammation is also closely associated with oxidative stress. Oxidative stress and inflammation can affect our overall digestive health. �
Oxidative Stress
Fasting can help reduce inflammation and oxidative stress through our genes. Oxidative stress refers to the damage that happens to the cells and tissues of the human body when exposed to a variety of environmental factors, such as toxins. Proteins, lipids, and even the DNA of our cells can be affected by inflammation and oxidative stress, altering the structure and function of the cells. Eating antioxidants can help reduce inflammation and oxidative stress. It’s essential you make sure you consume enough antioxidants when you’re not fasting in order to prevent cell damage from inflammation and oxidative stress.
Fasting and the MMC for Digestive Health
Researchers and healthcare professionals have suggested that the development of several digestive health issues, including SIBO, IBS, and leaky gut, is associated with increased levels of oxidative enzymes as well as decreased amounts of antioxidant enzymes. However, the main source of these digestive health issues ultimately involves the gut microbiome or the bacteria in the gut. Small intestinal bacterial overgrowth, or SIBO, is a digestive health issue caused by the excess growth of the bacteria in the small intestine, eventually leading to leaky gut or intestinal permeability, among other problems. �
According to research studies and clinical trials, fasting can help change the population of the gut microbiome, encouraging the regulation of “healthy” bacteria. This digestive process is ultimately controlled by the migrating motor complex or the MMC. The MMC is a digestive process which regulates and maintains gastrointestinal, or GI, tract contractions throughout a period of time. The migrating motor complex helps sweep bacteria and undigested debris out for elimination as waste. Neurohormonal signals, such as somatostatin, serotonin, motilin, and ghrelin, control the MMC when eating and fasting. �
MMC activity triggers when we are fasting or in between meals. Once we consume food, however, nutrients like vitamins and minerals can affect the activation of the migrating motor complex, ultimately decreasing when MMC activity triggers, and essentially starting the digestive process once again. If we allow the MMC to complete its work during fasting, it can become much more difficult for food, undigested debris, and excess bacteria to stay in the gastrointestinal, or GI, tract. This is why fasting has been recommended as a treatment for SIBO. However, fasting may not be suitable for everyone. Although fasting can have a variety of digestive health benefits, make sure to contact a doctor before starting any fasting treatment plan or program. �
Fasting is a well-known, strategical way of eating which can have a variety of digestive health benefits for many people. Several digestive health issues, such as SIBO, IBS, and leaky gut, may tremendously benefit from fasting. Small intestinal bacterial overgrowth, or SIBO, is a severe health issue that causes excess bacteria to grow in the small intestine. Fasting can promote the migrating motor complex, or the MMC, to activate, sweeping excess bacteria and undigested debris away for elimination as waste, also triggering anti-inflammatory processes to reduce inflammation and oxidative stress. However, fasting may not be for everyone. Make sure to talk to a qualified and experienced healthcare professional before fasting. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
Neurotransmitter Assessment Form
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �
For many people, fasting, or the concept of willingly skipping meals for a specific period of time, may not seem like a very appealing way to improve digestive health. Because most people also eat about 3 meals a day, skipping one or two meals a day can ultimately cause them to feel moody, tired, and fatigued. However, for people with digestive health issues, such as SIBO, IBS, or leaky gut, they may already be feeling these symptoms, even after eating their 3 meals a day. In this article, we discussed how fasting can be beneficial for some patients and how it can help improve their digestive health. �
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez �
References:
Rory. �How To Heal Your Gut With Fasting.� Chewsomegood, MSc Personalised Nutrition, 9 Aug. 2018, www.chewsomegood.com/fasting-ibs/.
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �
Neural Zoomer Plus for Neurological Disease
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �
Food Sensitivity for the IgG & IgA Immune Response
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �
Formulas for Methylation Support
XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
�
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download �
* All of the above XYMOGEN policies remain strictly in force. �
If you are experiencing any of these situations, then your hippocampus might be lowered than usual.
The Hippocampus
In the brain, there is an S-shaped structured located in the inner folds in the temporal lobe called the hippocampus. The hippocampus is a complex brain structure that has a layer of densely packed neurons, and its primary function involves how humans learn and how their memory works. The hippocampus is part of the limbic system as well since it works the feeling and reacting function in the body. The limbic system is situated at the edge of the cortex and includes the hypothalamus and the amygdala.
These structures help controls the body�s different functions like the endocrine system and the �fight or flight� reaction response. With the hippocampus helping humans process what information they are learning, this structure can retrieve two kinds of memories that are important; they are declarative memories and spatial relationship memories.
Declarative memories: These are memories that are related to facts and events a person experience. It includes examples like how to memorize speeches or line in a play that a person is doing.
Spatial relationship memories: These memories involve pathways or routes that a person must learn. An example of this is transportation drivers like cab drivers, bus drivers, and truckers who have to learn the routes in the places they are going to. So they use spatial memory and practice their routes many times until they have it in their memories. The spatial relationship memories are stored on the right side of the hippocampus.
Sadly though, the hippocampus can be damaged by neurological diseases like Alzheimer�s disease and PTSD (Post-Traumatic Stress Disorder). When it is damaged, a variety of conditions can affect the hippocampus�s ability to do its job for the brain, thus making the individual suffer from retaining information.
Hippocampus Conditions
Several conditions can cause problems to the body when the hippocampus is damaged. This is known as hippocampus atrophy, where the neurons and neuronal volume in the hippocampal that is a loss.
Alzheimer�s Disease
Alzheimer�s disease is when an individual begins to lose their memory. When the hippocampus is damaged, it can cause a dissociation between the cortexes and leads to information registration failure. Studies show that when Alzheimer�s disease is progressing, the hippocampus will lose its volume, and it will become harder for an individual to function in their daily lives.
Epilepsy
When a person has epilepsy, it might be due to a damaged hippocampus. Research shows that around 50 to 75% of patients with this disease may have hippocampal sclerosis, and in case they have died, they have medial temporal lobe epilepsy. More research states that the mechanics of hippocampal sclerosis in epilepsy can be related to the development of inflammation on the uncontrolled local hippocampus and blood-brain barrier damage.
Hypertension
When the hippocampus is damaged, hypertension can happen to a person. Hypertension is another name for high blood pressure, and it can lead to severe health complications to the body. Even though the causes of hypertension are still unknown, the risk factors from hypertension can include:
Environmental factors like stress or a lack of exercise
Hormone activity
Blood plasma
Studies show that hypertension and other risk factors are being increasingly viewed as a putative factor that is leading to hippocampal atrophy.
Cushing�s Disease
Cushing�s disease or Cushing syndrome is when the body is exposed to high levels of cortisol for a long time. Studies show that when there is a loss of cellular volume to the corticosteroid�s levels in the body and it could be responsible. When there is too much cortisol being produced in the body, it is one of the signs of Cushing syndrome. Some of the other signs include:
Weight gain
Fatty tissue deposits around the midsection, face, upper back and between the shoulders
Pink or purple stretch marks
Thinning, fragile skin that bruises easily
Slow healing cuts, insect bites and infections
Acne
Muscle weakness
Cognitive difficulties
Loss of emotional control
Since stress does play a role in the endocrine system and the neurological system, there are nearly 80 years of research on how much focus has been on the various levels of the HPA (hypothalamic-pituitary-adrenal) axis and the hormones it produces. It shows that glucocorticoids as the mediators for the stress effects on the hippocampus and being the contributing factor for stress-associated psychopathologies.
Conclusion
The hippocampus is located in the temporal lobe of the brain. This S-shaped structure can be easily damaged due to stress and other neurological factors that can affect the entire body and its systems. When harmful factors affect the hippocampus, it can lead the hormones that are producing to become imbalanced and cause dysfunction. Some products are here to make sure that the endocrine system is functioning properly and supporting the metabolic system, the gastrointestinal system, as well as making sure the hormones are balanced.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
References:
Anand, Kuljeet Singh, and Vikas Dhikav. �Hippocampus in Health and Disease: An Overview.� Annals of Indian Academy of Neurology, Medknow Publications & Media Pvt Ltd, Oct. 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3548359/.
Dresden, Danielle. �Hippocampus: Function, Size, and Problems.� Medical News Today, MediLexicon International, 7 Dec. 2017, www.medicalnewstoday.com/articles/313295.php.
Felman, Adam. �Hypertension: Causes, Symptoms, and Treatments.� Medical News Today, MediLexicon International, 22 July 2019, www.medicalnewstoday.com/articles/150109.php.
Kim, Eun Joo, et al. �Stress Effects on the Hippocampus: a Critical Review.� Learning & Memory (Cold Spring Harbor, N.Y.), Cold Spring Harbor Laboratory Press, 18 Aug. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4561403/.
Team, Mayo Clinic. �Cushing Syndrome.� Mayo Clinic, Mayo Foundation for Medical Education and Research, 30 May 2019, www.mayoclinic.org/diseases-conditions/cushing-syndrome/symptoms-causes/syc-20351310.
Do you experience bloating after eating a meal? While many people may not experience this symptom, it’s important to understand that any amount of bloating is generally abnormal and it can be a sign of gut inflammation. If you regularly experience bloating, or you have irritable bowel syndrome (IBS), there�s a chance that you may have small intestinal bacterial overgrowth (SIBO). In the following article, we will discuss the top 10 red flags of SIBO. �
What is Small Intestinal Bacterial Overgrowth (SIBO)?
Small intestinal bacterial overgrowth (SIBO) is a digestive health issue that happens when there is excess bacteria in the small intestine. The bacteria in the gastrointestinal (GI) tract plays a fundamental role in the immune system and overall health and wellness. As a matter of fact, research studies have shown that the gut microbiome has tens of trillions of microorganisms, including more than 1,000 different species of bacteria with over 3 million genes. �
Most of the gut bacteria are found in the large intestine and colon, where they ultimately help break down food, synthesize vitamins or minerals, and eliminate waste. However, if the healthy bacteria commonly found in the large intestine and colon start to grow excessively in the small intestine, SIBO can occur. Small intestinal bacterial overgrowth can also be caused by an excess growth of “healthy” bacteria found in the small intestine itself. �
With SIBO, the excess bacteria may start to consume the undigested food in the small intestine, causing it to ferment and produce hydrogen. Moreover, hydrogen can “feed” single-celled microorganisms commonly found in the small intestine, known as archaea, which may then produce methane. Patients with SIBO have increased levels of hydrogen and/or methane in their digestive system. This formula can cause a variety of digestive health issues. �
Furthermore, patients with SIBO may also develop a variety of symptoms depending on which type of gas is predominantly produced in their gut. Hydrogen-dominant SIBO, by way of instance, generally causes diarrhea while methane-dominant SIBO, by way of instance, generally causes constipation. Small intestinal bacterial overgrowth doesn’t simply cause a variety of digestive health issues, SIBO can also cause a wide array of symptoms, including: �
10 Red Flags You May Have SIBO
Gas, bloating, and/or diarrhea
Abdominal pain, discomfort, and/or cramping
Constipation
Irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD)
Vitamin and mineral deficiencies (vitamins A, B12, D, and E)
Fat malabsorption (pale, bulky, and malodorous stools)
Rosacea and/or skin rashes
Leaky gut or intestinal permeability
Because there are many symptoms that can show that you may have small intestinal bacterial overgrowth, occasionally showing none of the red flags listed above, SIBO may frequently go undiagnosed. Approximately 6 to 15 percent of “healthy”, asymptomatic people, and about 80 percent of people with irritable bowel syndrome (IBS), may actually be suffering from SIBO. If you experience any of the previous symptoms, make sure to see a doctor immediately. �
What Causes Small Intestinal Bacterial Overgrowth (SIBO)?
When enzymes start to break down the food we eat, our gastrointestinal (GI) tract depends on the proper function of nerves, muscles, and neurotransmitters to move the food accordingly throughout our digestive system, from the stomach to the small intestine and to the colon. In a healthy gut, bacteria pass through the gastrointestinal (GI) tract together with the food we eat into the colon. Symptoms and health issues may start when this process is affected. �
Damaged or injured nerves and/or muscles in the gut can ultimately cause leftover bacteria to stay longer in the small intestine, increasing the risk of SIBO. By way of instance, diabetes mellitus and scleroderma are two health issues that can both affect the muscles in the gut, causing SIBO to develop. �
Physical obstructions in the gut, such as scarring from surgeries or Crohn�s disease, can also cause excess bacteria to grow in the small intestine. Diverticuli, tiny pouches that can develop in the wall of the small intestine, can also start to collect bacteria instead of passing it to the colon. �
Drugs and/or medications that can affect or interrupt our healthy gut microbiome. This can include antibiotics, acid-blocking medicine, and steroids. In addition, it’s essential to mention that one of the most common causes of small intestinal bacterial overgrowth (SIBO) is a poor diet that is high in sugar, refined carbohydrates, and alcohol. If you suspect you may have SIBO, make sure you talk to a healthcare professional for diagnosis and treatment. �
Small intestinal bacterial overgrowth (SIBO) is a serious health issue which usually occurs because of an underlying chronic health issue. Several common symptoms may ultimately help determine the presence of SIBO. Several red flags may ultimately suggest the presence of small intestinal bacterial overgrowth but, because some people may not experience any symptoms, it can often go undiagnosed. Proper diagnosis is fundamental. SIBO, or small intestinal bacterial overgrowth is treatable. Patients should contact a healthcare professional immediately if they suspect they have SIBO so that they can begin treatment right away. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
Neurotransmitter Assessment Form
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �
Do you experience bloating after eating a meal? While many people may not experience this symptom, it’s important to understand that any amount of bloating is generally abnormal and it can be a sign of gut inflammation. If you regularly experience bloating, or you have irritable bowel syndrome (IBS), there�s a chance that you may have small intestinal bacterial overgrowth (SIBO). In the article above, we discussed the top 10 red flags of SIBO.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez �
References:
Myers, Amy. �10 Signs You Have Small Intestinal Bacterial Overgrowth (SIBO).� Amy Myers MD, 12 Nov. 2019, www.amymyersmd.com/2018/04/10-signs-small-intestinal-bacterial-overgrowth-sibo/.
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �
Neural Zoomer Plus for Neurological Disease
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �
Food Sensitivity for the IgG & IgA Immune Response
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �
Formulas for Methylation Support
� XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
�
�
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download �
* All of the above XYMOGEN policies remain strictly in force. �
Do you have difficulty digesting protein-rich foods? Do you have difficulty digesting starch-rich foods? Do you have difficulty digesting fatty or greasy foods? Do you experience abdominal distention after meals? Do you have abdominal pain and inflammation? If so, you may be having SIBO symptoms. �
Small intestinal bacterial overgrowth (SIBO) is a gastrointestinal (GI) tract health issue that can become a persistent problem if it’s not managed accordingly, especially if it’s ultimately left untreated. For many people suffering from chronic gas, bloating, constipation, and/or diarrhea, they may have also already had a diagnosis of irritable bowel syndrome (IBS). However, research studies have shown that one of the main causes of IBS may be SIBO. �
SIBO is a digestive health issue where there are too many bacteria in the small intestine. Bacterial overgrowth can also cause IBS. Although there are many treatment options for SIBO, one of the most important treatments for SIBO is doing everything we can to help keep SIBO from coming back. The purpose of the following article is to discuss how understanding the migrating motor complex (MMC) can help treat small intestinal bacterial overgrowth (SIBO). �
What is the Migrating Motor Complex?
The migrating motor complex (MMC) refers to the collection of electrical waves that occur in the gut. The MMC helps regulate several important functions of the gut, such as sweeping out the stuff we no longer need in there and moving it down to the colon where it can then be excreted by the human body. �
Phases of the Migrating Motor Complex
The MMC is how the digestive system eliminates waste from the human body. The MMC cycle includes four phases, including:� �
The first phase is a period of calmness that lasts 45 to 60 minutes where rare action potentials and contractions occur.
The second phase is a period of about 30 minutes where peristaltic contractions occur and gradually increase in frequency. Peristalsis starts in the stomach and continues throughout the small intestine.
The third phase lasts 5 to 15 minutes and it’s made-up of rapid, evenly spaced out peristaltic contractions. The pylorus stays open during these peristaltic contractions which allow many indigestible materials to pass into the small intestine.
The fourth and final phase is a period of transition between the contractions from the third phase and the inactivity from the first phase.
Gastric, biliary, and pancreatic secretion increases during the MMC to further with the digestion process as well as to help decrease bacteria in the gastrointestinal (GI) tract. Healthcare professionals believe that motilin, the enteric hormone, regulates the MMC. Because eating food can interrupt the MMC, fasting between meals is important to help complete the four phases. Moreover, the well-known �growling” sounds you generally hear when you are hungry may be the migrating motor complex performing its job functions accordingly, such as cleaning your bowels of waste and excessive bacteria. �
Migrating Motor Complex (MMC) Health Issues
If the migrating motor complex (MMC) isn’t working properly, the foods we consume may ultimately remain in the stomach and small intestine longer than what is generally considered to be healthy, which can make us feel a heaviness after eating or it can make us feel too-full, even if you’ve only had a small meal. Furthermore, a slow MMC can also cause bacteria to stay in the gastrointestinal (GI) tract for too long, which can also lead to SIBO. � Approximately 70 percent of people with SIBO also have MMC health issues. Research studies have shown that reduced MMC function may be associated with excess methane and/or hydrogen gasses produced by the excess bacteria in the gut. SIBO can also increase inflammation and intestinal permeability. �
Other research studies have shown that utilizing acid-reducing medications or an H. pylori infection can affect MMC function. Lack of exercise, grazing, and constipation can also affect MMC. Stress can also affect MMC function. Finally, thyroid problems and adrenal fatigue can also affect MMC function. �
Research studies have shown that people with IBS can frequently have decreased MMC function although researchers still don’t understand how these changes occur. Several researchers believe that food poisoning and other bacterial infections can affect the gut microbiome which then changes how the gut microbiome signals the MMC to start and stop. Eating inflammatory foods or foods that you�re sensitive and/or allergic to can also cause nerve damage in the gut. Subsequently, these damaged nerves then can�t properly signal the MMC to function accordingly, leading to SIBO and other health issues. �
Small intestinal bacterial overgrowth (SIBO) is a serious health issue which usually occurs because of an underlying chronic health issue. Several common symptoms may ultimately help determine the presence of SIBO. In addition, research studies have demonstrated that poor migrating motor complex (MMC) function, or the collection of electrical waves that help regulate several important functions of the gut, can ultimately cause SIBO and other digestive system health issues if left untreated. SIBO, or small intestinal bacterial overgrowth is treatable. Patients should contact a healthcare professional immediately if they suspect they have SIBO so that they can begin treatment right away. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �
Do you have difficulty digesting protein-rich foods? Do you have difficulty digesting starch-rich foods? Do you have difficulty digesting fatty or greasy foods? Do you experience abdominal distention after meals? Do you have abdominal pain and inflammation? If so, you may be having SIBO symptoms. �
Small intestinal bacterial overgrowth (SIBO) is a gastrointestinal (GI) tract health issue that can become a persistent problem if it’s not managed accordingly, especially if it’s ultimately left untreated. For many people suffering from chronic gas, bloating, constipation, and/or diarrhea, they may have also already had a diagnosis of irritable bowel syndrome (IBS). However, research studies have shown that one of the main causes of IBS may be SIBO. �
SIBO is a digestive health issue where there are too many bacteria in the small intestine. Bacterial overgrowth can also cause IBS. Although there are many treatment options for SIBO, one of the most important treatments for SIBO is doing everything we can to help keep SIBO from coming back. The purpose of the article above was to discuss how understanding the migrating motor complex (MMC) can help treat small intestinal bacterial overgrowth (SIBO).
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez �
References:
Albina, Victoria. �SIBO Begone: 5 Easy Ways to Keep Your SIBO From Coming Back.� Victoria Albina, Victoria Albina, 26 Mar. 2019, victoriaalbina.com/sibo/.
Brisson, John. �Migrating Motor Complex (MMC) and Digestive Health.� Fix Your Gut, Fix Your Gut, 13 Dec. 2014, www.fixyourgut.com/mmc-digestive-health/.
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �
Neural Zoomer Plus for Neurological Disease
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �
Food Sensitivity for the IgG & IgA Immune Response
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �
Formulas for Methylation Support
� XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
�
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download �
* All of the above XYMOGEN policies remain strictly in force. �
IFM's Find A Practitioner tool is the largest referral network in Functional Medicine, created to help patients locate Functional Medicine practitioners anywhere in the world. IFM Certified Practitioners are listed first in the search results, given their extensive education in Functional Medicine
