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Gut and Intestinal Health

Back Clinic Gut and Intestinal Health. The health of an individual’s gut determines what nutrients are absorbed along with what toxins, allergens, and microbes are kept out. It is directly linked to the health of the whole body. Intestinal health could be defined as optimal digestion, absorption, and assimilation of food. But this is a job that depends on many other factors. More than 100 million Americans have digestive problems. Two of the top-selling drugs in America are for digestive problems, and they run in the billions. There are more than 200 over-the-counter (OTC) remedies for digestive disorders. And these can and do create additional digestive problems.

If an individual’s digestion is not working properly, the first thing is to understand what is sending the gut out-of-balance in the first place.

  • A low-fiber, high-sugar, processed, nutrient-poor, high-calorie diet causes all the wrong bacteria and yeast to grow in the gut and damages the delicate ecosystem in your intestines.
  • Overuse of medications that damage the gut or block normal digestive function, i.e., acid blockers (Prilosec, Nexium, etc.), anti-inflammatory medication (aspirin, Advil, and Aleve), antibiotics, steroids, and hormones.
  • Undetected gluten intolerance, celiac disease, or low-grade food allergies to foods such as dairy, eggs, or corn.
  • Chronic low-grade infections or gut imbalances with overgrowth of bacteria in the small intestine, yeast overgrowth, parasites.
  • Toxins like mercury and mold toxins damage the gut.
  • Lack of adequate digestive enzyme function from acid-blocking medications or zinc deficiency.
  • Stress can alter the gut’s nervous system, cause a leaky gut, and change the normal bacteria.

Visits for intestinal disorders are among the most common trips to primary care doctors. Unfortunately, most, which also includes most doctors, do not recognize or know that digestive problems wreak havoc in the entire body. This leads to allergies, arthritis, autoimmune disease, rashes, acne, chronic fatigue, mood disorders, autism, dementia, cancer, and more. Having proper gut and intestinal health is absolutely central to your health. It is connected to everything that happens in the body.


Anatomy of the Digestive System | Wellness Clinic

Anatomy of the Digestive System | Wellness Clinic

Food is one of the most essential basic needs. It is made up of nutrients, micronutrients, such as vitamins and minerals, and macronutrients, such as carbohydrates, proteins and fats. A balanced diet, consisting of a variety of these nutrients is the foundation of good health. While consuming the necessary daily intake of carbohydrates, high-quality proteins, heart-healthy fats, vitamins, minerals and water is essential towards maintaining the body’s overall well-being and function, staying healthy and productive could not be achieved without one important structure: the digestive system.

 

What is the digestive system?

 

The digestive system is a collective group of organs which function together to convert food into energy and provide basic, fundamental nutrients in order to nourish the entire body. Food is delivered through a long tube inside the body known as the alimentary canal, best referred to as the gastrointestinal tract, or the GI tract. The gastrointestinal tract consists of the oral cavity, or mouth, pharynx, esophagus, stomach, small intestines, and large intestines. Along with the gastrointestinal tract, there are various important accessory organs which additionally help the human body to digest foods, however, these do not have food pass through them. Accessory organs of the digestive system include the teeth, the tongue, salivary glands, liver, gallbladder, and the pancreas.

 

Digestive System Anatomy Diagram | Wellness Clinic

 

Digestive System Anatomy

 

Mouth

 

Food begins its course through the digestive system at the mouth, also known as the oral cavity. As a matter of fact, digestion is considered to begin here as soon as you take the first bite of a meal. Within the mouth are numerous accessory organs which aid in the digestion of food: the teeth, the tongue, and the salivary glands. Teeth chop food into smaller pieces, to allow for an easier digestion, which are then moistened by saliva to begin the process of breaking the food down, before the tongue and other muscles of the mouth push the food into the pharynx.

 

  • Teeth. The teeth are 32 small, hard organs located along the anterior and lateral edges of the mouth. Each tooth is created from a bone-like material called dentin and coated in a layer of enamel, the hardest substance in the human body. Teeth are living organs that also contain blood vessels and nerves under the dentin in a soft region, best referred to as the pulp. The structure of the teeth is made for cutting and grinding food into smaller pieces.
  • Tongue. The tongue is located on the inferior section of the mouth only posterior and medial to teeth. It’s a small organ composed of several pairs of muscles coated in a thin but strong, bumpy, skin-like layer. The outside of the tongue contains many papillae designed for grasping food as it’s moved by the tongue’s muscles. The taste buds on the surface of the tongue distinguish flavor molecules in food and link to nerves in the tongue to deliver taste information to the brain. The tongue can also help push food toward the posterior area of the mouth for swallowing.
  • Salivary Glands. Surrounding the mouth are three varieties of salivary glands. The salivary glands are sets of accessory organs that produce a watery secretion known as saliva. Saliva helps to moisten food and starts the digestion of food. The body also uses saliva to continue lubricating food as it moves through the mouth, pharynx, and esophagus.

 

Pharynx

 

The pharynx, or throat, is a funnel-shaped tube connected to the back end of their mouth. The pharynx is responsible for the delivery of a mass of chewed food from the mouth to the esophagus. The pharynx also has a significant role in the respiratory system, as air from the nasal cavity passes through the pharynx on its way to the larynx and finally the lungs. Since the pharynx serves two different functions, it includes a flap of tissue called the epiglottis which behaves as a switch to effectively route food into the esophagus and air into the larynx.

 

Esophagus

 

The esophagus is a muscular tube which connects the pharynx to the stomach, that is part of the upper gastrointestinal tract, or upper GI tract. By means of a series of contractions, referred to as peristalsis, it transports the eaten masses of chewed food along its span. At the inferior end of the esophagus is a muscular ring known as the lower esophageal sphincter or cardiac sphincter. The role of the sphincter is to shut off the end of the esophagus and keep food from passing backwards into the esophagus, and instead maintain it in the stomach.

 

Stomach

 

The stomach is a muscular sac that’s located on the left side of the abdominal cavity, just inferior to the diaphragm. In an average individual, the stomach is about the size of their two fists placed alongside each other. This major organ plays the role of serving as a sort of storage tank for foods so the body has enough time to digest large meals properly. The stomach also contains hydrochloric acid and digestive enzymes which continue the digestion of food that began from the mouth. When it leaves the stomach, food is the consistency of a liquid or paste.

 

Small Intestine

 

Made up of three segments, the duodenum, the jejunum and the ileum, the small intestine is a long, thin tube about 1 inch in diameter and approximately 10 feet long which is part of the lower gastrointestinal tract, or lower GI tract. It is located only inferior to the stomach and takes up nearly all the space in the abdominal cavity. The entire small intestine is coiled like a hose and the interior surface is filled with lots of ridges and folds. These folds are utilized to make the most of the digestion of food and absorption of nutrients. The small intestine continues the process of breaking down food with the help of accessory organs. Contractions known as peristalsis are also at work within this organ. By the time food leaves the small intestine, approximately 90 percent of nutrients are extracted from the food which entered it.

 

Liver and Gallblader

 

The liver is a roughly triangular accessory organ of the digestive system found to the right of the stomach, just inferior to the diaphragm and superior to the small intestine. The liver weighs about 3 pounds and is the second largest organ in the human body. The liver has many different functions, but its primary purpose is the production of bile and its secretion into the small intestine for digestion. Another of its important functions include the cleansing and purification of the blood flowing from the small intestine, which contains the absorbed nutrients. The gallblader is a small, pear-shaped organ found just posterior to the liver. The gallbladder is used to store and recycle surplus bile from the small intestine, through a channel known as the cystic duct, so that it might be re-utilized for the digestion of subsequent meals.

 

Pancreas

 

The pancreas is a large gland situated just inferior and posterior to the stomach. It is approximately 6 inches long and shaped like short, lumpy snake with its “head” attached into the duodenum and its “tail” pointing towards the left wall of the abdominal cavity. The pancreas secretes digestive enzymes into the small intestine to complete the digestion of foods. These enzymes break down carbohydrates, proteins and fats from the food we eat.

 

Large Intestine

 

The large intestine, best referred to as the colon, is a long, thick tube about 2.5 inches in diameter and approximately 5 feet long.�It is made up of the cecum, the ascending colon, the transverse colon, the descending colon, and the sigmoid colon, which connects to the rectum. It is located only inferior to the stomach and wraps across the lateral and superior border of the small intestine. The large intestine absorbs water and also contains many symbiotic bacteria which aid in the breaking down of wastes to extract small quantities of nutrients. Stool, or waste left over from the digestive process, is passed through the colon by means of peristalsis, or contractions, first in a liquid state and ultimately in solid form as the water is removed from the stool. Stool, or feces, in the large intestine exits the body through the anal canal, to begin the process of elimination.

 

In conclusion, the digestive system is ultimately essential to effectively break down the food we consume to provide our body with energy and basic nutrients. Unfortunately, however, as with other systems of the body, gastrointestinal diseases can alter the healthy function of the digestive system. The gastrointestinal tract may appear normal but may not be working properly. Symptoms can vary widely on the individual depending on the problem.� We will discuss the common issues affecting the gastrointestinal tract, or GI tract, including the colon as well as rectum and anal problems, in the following series of articles.�The scope of our information is limited to chiropractic and spinal injuries and conditions. To discuss the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .

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By Dr. Alex Jimenez

 

Additional Topics: Wellness

 

Overall health and wellness are essential towards maintaining the proper mental and physical balance in the body. From eating a balanced nutrition as well as exercising and participating in physical activities, to sleeping a healthy amount of time on a regular basis, following the best health and wellness tips can ultimately help maintain overall well-being. Eating plenty of fruits and vegetables can go a long way towards helping people become healthy.

 

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TRENDING TOPIC: EXTRA EXTRA: How to Become a Healthier You!

 

GM Crops: The  Limitations, Risks, And Alternatives

GM Crops: The Limitations, Risks, And Alternatives

GM Crops: Proponents claim that genetically modified (GM) crops:

 

  • are safe to eat and more nutritious
  • beneft the environment
  • reduce use of herbicides and insecticides
  • increase crop yields, thereby helping farmers and solving the food crisis
  • create a more affuent, stable economy
  • are just an extension of natural breeding, and have no risks different from naturally bred crops.

However, a large and growing body of scientifc research and on-the-ground experience indicate that GMOs fail to live

up to these claims. Instead, GM crops:

 

  • can be toxic, allergenic or less nutritious than their natural counterparts
  • can disrupt the ecosystem, damage vulnerable wild plant and animal populations and harm biodiversity
  • increase chemical inputs (pesticides, herbicides) over the long term
  • deliver yields that are no better, and often worse, than conventional crops
  • cause or exacerbate a range of social and economic problems
  • are laboratory-made and, once released, harmful GMOs cannot be recalled from the environment.

The scientifically demonstrated risks and clear absence of real benefits have led experts to see GM as a clumsy, outdated technology. They present risks that we need not incur, given the availability of effective, scientifically proven, energy-efficient and safe ways of meeting current and future global food needs.

This paper presents the key scientific evidence � 114 research studies and other authoritative documents � documenting the limitations and risks of GM crops and the many safer, more effective alternatives available today.

Is GM An Extension Of Natural Plant Breeding?

Natural reproduction or breeding can only occur between closely related forms of life (cats with cats, not cats with dogs; wheat with wheat, not wheat with tomatoes or fish). In this way, the genes that offspring inherit from parents, which carry information for all parts of the body, are passed down the generations in an orderly way.

GM is not like natural plant breeding. GM uses laboratory techniques to insert artificial gene units to re-program the DNA blueprint of the plant with completely new properties. This process would never happen in nature. The artificial gene units are created in the laboratory by joining fragments of DNA, usually derived from multiple organisms, including viruses, bacteria, plants and animals. For example, the GM gene in the most common herbicide resistant soya beans was pieced together from a plant virus, a soil bacterium and a petunia plant.

The GM transformation process of plants is crude, imprecise, and causes widespread mutations, resulting in major changes to the plant�s DNA blueprint1. These mutations unnaturally alter the genes� functioning in unpredictable and potentially harmful ways2, as detailed below. Adverse effects include poorer crop performance, toxic effects, allergic reactions, and damage to the environment.Are GM foods safe to eat?Contrary to industry claims, GM foods are not properly tested for human safety before they are released for sale3 4. In fact, the only published study directly testing the safety of a GM food on humans found potential problems5. To date, this study has not been followed up. Typically the response to the safety question is that people have been eating GM foods in the United States and elsewhere for more than ten years without ill effects and that this proves that the products are safe. But GM foods are not labelled in the US and other nations where they are widely eaten and consumers are not monitored for health effects.

Because of this, any health effects from a GM food would have to meet unusual conditions before they would be noticed. The health effects would have to:

� occur immediately after eating a food that was known to be GM (in spite of its not being labeled). This kind of response is called acute toxicity.

� cause symptoms that are completely different from common diseases. If GM foods caused a rise in common or slow-onset diseases like allergies or cancer, nobody would know what caused the rise.

� be dramatic and obvious to the naked eye. Nobody examines a person�s body tissues with a microscope for harm after they eat a GM food. But just this type of examination is needed to give early warning of problems such as pre-cancerous changes.

To detect important but more subtle effects on health, or effects that take time to appear (chronic effects), long-term controlled studies on larger populations are required.

Under current conditions, moderate or slow-onset health effects of GM foods could take decades to become known, just as it took decades for the damaging effects of trans-fats (another type of artificial food) to be recognized. �Slow poison� effects from trans-fats have caused millions of premature deaths across the world6 .

Another reason why any harmful effects of GM foods will be slow to surface and less obvious is because, even in the United States, which has the longest history of GM crop consumption, GM foods account for only a small part of the US diet (maize is less than 15% and soya bean products are less than 5%).

Nevertheless, there are signs that all is not well with the US food supply. A report by the US Centers for Disease Control shows that food-related illnesses increased 2- to 10-fold in the years between 1994 (just before GM food was commercialized) and 19997 . Is there a link with GM food? No one knows, because studies on humans have not been done.

Animal Studies On GM Foods Give Cause For Concern

Although studies on humans have not been done, scientists are reporting a growing number of studies that examine the effects of GM foods on laboratory animals. These studies, summarized below, raise serious concerns regarding the safety of GM foods for humans as well as animals.

Small Animal Feeding Studies

� Rats fed GM tomatoes developed stomach ulcerations8

� Liver, pancreas and testes function was disturbed in mice fed GM soya9 10 11

� GM peas caused allergic reactions in mice12

� Rats fed GM oilseed rape developed enlarged livers, often a sign of toxicity13

� GM potatoes fed to rats caused excessive growth of the lining of the gut similar to a pre-cancerous condition14 15

� Rats fed insecticide-producing GM maize grew more slowly, suffered problems with liver and kidney function, and showed higher levels of certain fats in their blood16

� Rats fed GM insecticide-producing maize over three generations suffered damage to liver and kidneys and showed alterations in blood biochemistry17

� Old and young mice fed with GM insecticide-producing maize showed a marked disturbance in immune system cell populations and in biochemical activity18

� Mice fed GM insecticide-producing maize over four generations showed a buildup of abnormal structural changes in various organs (liver, spleen, pancreas), major changes in the pattern of gene function in the gut, reflecting disturbances in the chemistry of this organ system (e.g. in cholesterol production, protein production and breakdown), and, most significantly, reduced fertility19

� Mice fed GM soya over their entire lifetime (24 months) showed more acute signs of aging in their liver20

� Rabbits fed GM soya showed enzyme function disturbances in kidney and heart21.

Feeding Studies With Farm Animals

Farm animals have been fed GM feed for many years. Does this mean that GM feed is safe for livestock? Certainly it means that effects are not acute and do not show up immediately. However, longer-term studies, designed to assess slow-onset and more subtle health effects of GM feed, indicate that GM feed does have adverse effects, confirming the results described above for laboratory animals.

The following problems have been found:

� Sheep fed Bt insecticide-producing GM maize over three generations showed disturbances in the functioning of the digestive system of ewes and in the liver and pancreas of their lambs22.

� GM DNA was found to survive processing and to be detectable in the digestive tract of sheep fed GM feed. This raises the possibility that antibiotic resistance and Bt insecticide genes can move into gut bacteria23, a process known as horizontal gene transfer. Horizontal gene transfer can lead to antibiotic resistant disease causing bacteria (�superbugs�) and may lead to Bt insecticide being produced in the gut with potentially harmful consequences. For years, regulators and the biotech industry claimed that horizontal gene transfer would not occur with GM DNA, but this research challenges this claim

� GM DNA in feed is taken up by the animal�s organs. Small amounts of GM DNA appear in the milk and meat that people eat24 25 26. The effects on the health of the animals and the people who eat them have not been researched.

Do Animal Feeding Studies Highlight Potential Health Problems For People?

Before food additives and new medicines can be tested on human subjects, they have to be tested on mice or rats. If harmful effects were to be found in these initial animal experiments, then the drug would likely be disqualified for human use. Only if animal studies reveal no harmful effects can the drug be further tested on human volunteers.

But GM crops that caused ill effects in experimental animals have been approved for commercialization in many countries. This suggests that less rigorous standards are being used to evaluate the safety of GM crops than for new medicines.

In fact, in at least one country � the United States � safety assessment of GMOs is voluntary and not required by law, although, to date, all GMOs have undergone voluntary review. In virtually all countries, safety assessment is not scientifically rigorous. For instance, the animal feeding studies that GM crop developers routinely conduct to demonstrate the safety of their products are too short in duration and use too few subjects to reliably detect important harmful effects.27

While industry conducts less than rigorous studies on its own GM products, 28 it has, in parallel, systematically and persistently interfered with the ability of independent scientists to conduct more rigorous and incisive independent research on GMOs. Comparative and basic agronomic studies on GMOs, assessments of safety and composition, and assessments of environmental impact have all been restricted and suppressed by the biotechnology industry.29 30

Patent rights linked with contracts are used to restrict access of independent researchers to commercialized GM seed. Permission to study patented GM crops is either withheld or made so difficult to obtain that research is effectively blocked. In cases where permission is finally given, biotech companies keep the right to block publication, resulting in much significant research never being published.31 32

The industry and its allies also use a range of public relations strategies to discredit and/or muzzle scientists who do publish research that is critical of GM crops.33

Are GM Foods More Nutritious?

There are no commercially available GM foods with improved nutritional value. Currently available GM foods are no better and in some cases are less nutritious than natural foods. Some have been proven in tests to be toxic or allergenic.

Examples include:

� GM soya had 12�14% lower amounts of cancer-fighting isoflavones than non-GM soya34

� Oilseed rape engineered to have vitamin A in its oil had much reduced vitamin E and altered oil-fat composition35

� Human volunteers fed a single GM soya bean meal showed that GM DNA can survive processing and is detectable in the digestive tract. There was evidence of horizontal gene transfer to gut bacteria36 37. Horizontal gene transfer of antibiotic resistance and Bt insecticide genes from GM foods into gut bacteria is an extremely serious issue. This is because the modified gut bacteria could become resistant to antibiotics or become factories for Bt insecticide. While Bt in its natural form has been safely used for years as an insecticide in farming, Bt toxin genetically engineered into plant crops has been found to have potential ill health effects on laboratory animals38 39 40

� In the late 1980s, a food supplement produced using GM bacteria was toxic41, initially killing 37 Americans and making more than 5,000 others seriously ill.

� Several experimental GM food products (not commercialized) were found to be harmful:

� People allergic to Brazil nuts had allergic reactions to soya beans modified with a Brazil nut gene42

� The GM process itself can cause harmful effects. GM potatoes caused toxic reactions in multiple organ systems43 44. GM peas caused a 2-fold allergic reaction � the GM protein was allergenic and stimulated an allergic reaction to other food components45. This raises the question of whether GM foods cause an increase in allergies to other substances.

Can GM Foods Help Alleviate The World Food Crisis?

The root cause of hunger is not a lack of food, but a lack of access to food. The poor have no money to buy food and increasingly, no land on which to grow it. Hunger is fundamentally a social, political, and economic problem, which GM technology cannot address.

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Recent reports from the World Bank and the United Nations Food and Agriculture Organization have identified the biofuels boom as the main cause of the current food crisis46 47. But GM crop producers and distributors continue to promote the expansion of biofuels. This suggests that their priority is to make a profit, not to feed the world.

GM companies focus on producing cash crops for animal feed and biofuels for affluent countries, not food for people.

GM crops contribute to the expansion of industrial agriculture and the decline of the small farmer around the world. This is a serious development as there is abundant evidence that small farms are more efficient than large ones, producing more crops per hectare of land48 49 50 51 52.

Do GM Crops Increase Yield Potential?

At best, GM crops have performed no better than their non-GM counterparts, with GM soya beans giving consistently lower yields for over a decade54. Controlled comparative field trials of GM/non-GM soya suggest that 50% of the drop in yield is due to the genetic disruptive effect of the GM transformation process55. Similarly, field tests of Bt insecticide-producing maize hybrids showed that they took longer to reach maturity and produced up to 12% lower yields than their non-GM counterpart56.

A US Department of Agriculture report confirms the poor yield performance of GM crops, saying, �GE crops available for commercial use do not increase the yield potential of a variety. In fact, yield may even decrease…. Perhaps the biggest issue raised by these results is how to explain the rapid adoption of GE crops when farm financial impacts appear to be mixed or even negative57.�

The failure of GM to increase yield potential was emphasized in 2008 by the United Nations International Assessment of Agricultural Knowledge, Science and Technology for Development (IAASTD) report58. This report on the future of farming, authored by 400 scientists and backed by 58 governments, stated that yields of GM crops were �highly variable� and in some cases, �yields declined�. The report noted, �Assessment of the technology lags behind its development, information is anecdotal and contradictory, and uncertainty about possible benefits and damage is unavoidable.�

Failure To Yield

The definitive study to date on GM crops and yield is �Failure to Yield: Evaluating the Performance of Genetically Engineered Crops�. Published in 2009, the study is authored by former US EPA and Center for Food Safety scientist, Dr Doug Gurian-Sherman. It is based on published, peer-reviewed studies conducted by academic scientists and using adequate experimental controls.

In the study, Dr Gurian-Sherman distinguishes between intrinsic yield (also called potential yield), defined as the highest yield which can be achieved under ideal conditions, with operational yield, the yield achieved under normal field conditions when the farmer factors in crop reductions due to pests, drought, or other environmental stresses.

The study also distinguishes between effects on yield caused by conventional breeding methods and those caused by GM traits. It has become common for biotech companies to use conventional breeding and marker assisted breeding to produce higher-yielding crops and then finally to engineer in a gene for herbicide tolerance or insect resistance. In such cases, higher yields are not due to genetic engineering but to conventional breeding. �Failure to Yield� teases out these distinctions and analyses what contributions genetic engineering and conventional breeding make to increasing yield.

Based on studies on corn and soybeans, the two most commonly grown GM crops in the United States, the study concludes that genetically engineering herbicide-tolerant soybeans and herbicide-tolerant corn has not increased yields. Insect-resistant corn, meanwhile, has improved yields only marginally. The increase in yields for both crops over the last 13 years, the report finds, was largely due to traditional breeding or improvements in agricultural practices.

The author concludes: �commercial GE crops have made no inroads so far into raising the intrinsic or potential yield of any crop. By contrast, traditional breeding has been spectacularly successful in this regard; it can be solely credited with the intrinsic yield increases in the United States and other parts of the world that characterized the agriculture of the twentieth century.�59

Critics of the study have objected that it does not use data from developing countries. The Union of Concerned Scientists responds that there are few peer-reviewed papers evaluating the yield contribution of GM crops in developing countries � not enough to draw clear and reliable conclusions. However, the most widely grown food/feed crop in developing countries, herbicide-tolerant soybeans, offers some hints. Data from Argentina, which has grown more GM soybeans than any other developing country, suggest that yields for GM varieties are the same or lower than for conventional non-GE soybeans.60

�If we are going to make headway in combating hunger due to overpopulation and climate change, we will need to increase crop yields,� says Dr Gurian-Sherman. �Traditional breeding outperforms genetic engineering hands down.�61

If GM cannot improve intrinsic (potential) yield even in the affluent United States, where high-input, irrigated, heavily subsidized farming is the norm, it would seem irresponsible to assume that it would improve yields in the developing world, where increased food production is most needed. Initiatives promoting GM crops for the developing world are experimental and appear to be founded on expectations that are not consistent with data obtained in the West.

In the West, crop failure is often underwritten by governments, which bail out farmers with compensation. Such support systems are rare in the developing world. There, farmers may literally bet their farms and their entire livelihoods on a crop. Failure can have severe consequences.

Three GM Crops For Africa

GM sweet potato The virus-resistant sweet potato has been the ultimate GM showcase project for Africa, generating a vast amount of global media coverage. Florence Wambugu, the Monsanto trained scientist fronting the project, has been proclaimed an African heroine and the savior of millions, based on her claims about the GM sweet potato doubling output in Kenya. Forbes magazine even declared her one of a tiny handful of people around the globe who would �reinvent the future�.62 It eventually emerged, however, that the claims being made for the GM sweet potato were untrue, with field trial results showing the GM crop to be a failure.63 64

In contrast with the unproven GM sweet potato variety, a successful conventional breeding program in Uganda had produced a new high-yielding variety which is virus resistant and has �raised yields by roughly 100%�. The Ugandan project achieved success at a small cost and in just a few years. The GM sweet potato, in contrast, in over 12 years in the making, consumed funding from Monsanto, the World Bank, and USAID to the tune of $6 million.65

GM Cassava

The potential of genetic engineering to massively boost the production of cassava � one of Africa�s most important foods � by defeating a devastating virus has been heavily promoted since the mid-1990s. There has even been talk of GM solving hunger in Africa by increasing cassava yields as much as tenfold.66 But almost nothing appears to have been achieved. Even after it became clear that the GM cassava had suffered a major technical failure67, media stories continued to appear about its curing hunger in Africa.68 69 Meanwhile, conventional (non-GM) plant breeding has quietly produced virus resistant cassavas that are already making a remarkable difference in farmers� fields, even under drought conditions.70

Bt Cotton

In Makhatini, South Africa, often cited as the showcase Bt cotton project for small farmers, 100,000 hectares were planted with Bt cotton in 1998. By 2002, that had crashed to 22,500 hectares, an 80% reduction in 4 years. By 2004, 85% of farmers who used to grow Bt cotton had given up. The farmers found pest problems and no increase in yield. Those farmers who still grew the crop did so at a loss, continuing only because the South African government subsidized the project and there was a guaranteed market for the cotton.71

A study published in Crop Protection journal concluded, �cropping Bt cotton in Makhathini Flats did not generate sufficient income to expect a tangible and sustainable socioeconomic improvement due to the way the crop is currently managed. Adoption of an innovation like Bt cotton seems to pay only in an agro-system with a sufficient level of intensification.�72

How Will Climate Change Impact Agriculture?

Industrial agriculture is a major contributor to global warming, producing up to 20 per cent of greenhouse gas emissions, and some methods of increasing yield can exacerbate this negative impact. For example, crops that achieve higher intrinsic yield often need more fossil fuel based nitrogen fertilizer, some of which is converted by soil microbes into nitrous oxide, a greenhouse gas nearly 300 times more potent than carbon dioxide. Minimizing global agriculture�s future climate impact will require investment in systems of agriculture less dependent on industrial fertilizers and agroecological methods of improving soil water-holding capacity and resilience.

GM seeds are created by agrochemical companies and are heavily dependent on costly external inputs such as synthetic fertilizer, herbicides, and pesticides. It would seem risky to promote such crops in the face of climate change.

Peak Oil & Agriculture

According to some analysts, peak oil, when the maximum rate of global petroleum extraction is reached, has already arrived. This will have drastic effects on the type of agriculture we practice. GM crops are designed to be used with synthetic herbicides and fertilizers. But synthetic pesticides are made from oil and synthetic fertilizer from natural gas. Both these fossil fuels are running out fast, as are phosphates, a major ingredient of synthetic fertilizers.

Farming based on the current US GM and chemical model that depends on these fossil fuel-based inputs will become increasingly expensive and unsustainable. The statistics tell the story:

In the US food system, 10 kcal of fossil energy is required for every kcal of food consumed.73

� Approximately 7.2 quads of fossil energy are consumed in the production of crops and livestock in the U.S. each year.74 75

� Approximately 8 million kcal/ha are required to produce an average corn crop and other similar crops.76

� Two-thirds of the energy used in crop production is for fertilizers and mechanization.77

Proven technologies that can reduce the amount of fossil energy used in farming include reducing fertilizer applications, selecting farm machinery appropriate for each task, managing soil for conservation, limiting irrigation, and organic farming techniques.78

In the Rodale Institute Farming Systems Trial (FST), a comparative analysis of energy inputs conducted by Dr David Pimentel of Cornell University found that organic farming systems use just 63% of the energy required by conventional farming systems, largely because of the massive amounts of energy required to synthesize nitrogen fertilizer, followed by herbicide production.79

Studies show that the low-input organic model of farming works well in African countries. The Tigray project in Ethiopia, part-funded by the UN Food and Agriculture Organisation (FAO), compared yields from the application of compost and chemical fertilizer in farmers� fields over six years. The results showed that compost can replace chemical fertilizers and that it increased yields by more than 30 percent on average. As side-benefits to using compost, the farmers noticed that the crops had better resistance to pests and disease and that there was a reduction in �difficult weeds�.80

GM Crops & Climate Change

Climate change brings sudden, extreme, and unpredictable changes in weather. If we are to survive, the crop base needs to be as flexible, resilient and diverse as possible. GM technology offers just the opposite � a narrowing of crop diversity and an inflexible technology that requires years and millions of dollars in investment for each new variety.

Each GM crop is tailor-made to fit a particular niche. With climate change, no one knows what kind of niches will exist and where. The best way to insure against the destructive effects of climate change is to plant a wide variety of highperforming crops that are genetically diverse.

GM companies have patented plant genes that they believe are involved in tolerance to drought, heat, flooding, and salinity � but have not succeeded in using these genes to produce a single new crop with these properties. This is because these functions are highly complex and involve many different genes working together in a precisely regulated way. It is beyond existing GM technology to engineer crops with these sophisticated, delicately regulated gene networks for improved tolerance traits.

Conventional natural cross-breeding, which works holistically, is much better adapted to achieving this aim, using the many varieties of virtually every common crop that tolerate drought, heat, flooding, and salinity.

In addition, advances in plant breeding have been made using marker-assisted selection (MAS), a largely uncontroversial branch of biotechnology that can speed up the natural breeding process by identifying important genes. MAS does not involve the risks and uncertainties of genetic engineering.

The controversies that exist around MAS relate to gene patenting issues. It is important for developing countries to consider the implications of patent ownership relating to such crops.

Non-GM Successes For Niche Crops

If it is accepted that niche speciality crops may be useful in helping adaptation to climate change, there are better ways of creating them than genetic engineering. Conventional breeding and marker-assisted selection have produced many advances in breeding speciality crops, though these have garnered only a fraction of the publicity given to often speculative claims of GM miracles.

An example of such a non-GM success is the �Snorkel� rice that adapts to flooding by growing longer stems, preventing the crop from drowning.81 While genetic engineering was used as a research tool to identify the desirable genes, only conventional breeding � guided by Marker Assisted Selection � was used to generate the Snorkel rice line. Snorkel rice is entirely non-GM. This is an excellent example of how the whole range of biotechnology tools, including GM, can be used most effectively to work with the natural breeding process to develop new crops that meet the critical needs of today.

Are GM Crops Environmentally Friendly?

Two kinds of GM crops dominate the marketplace:

� Crops that resist broad-spectrum (kill-all) herbicides such as Roundup. These are claimed to enable farmers to spray herbicide less frequently to kill weeds but without killing the crop

� Crops that produce the insecticide Bt toxin. These are claimed to reduce farmers� need for chemical insecticide sprays.

Both claims require further analysis.

GM Crops & Herbicide Use

The most commonly grown herbicide-resistant GM crops are engineered to be resistant to Roundup. But the increasing use of Roundup has led to the appearance of numerous weeds resistant to this herbicide82. Roundup resistant weeds are now common and include pigweed83, ryegrass84, and marestail85. As a result, in the US, an initial drop in average herbicide use after GM crops were introduced has been followed by a large increase as farmers were forced to change their farming practices to kill weeds that had developed resistance to Roundup86 87. Farmers have increased radically the amounts of Roundup applied to their fields and are being advised to use increasingly powerful mixtures of multiple herbicides and not Roundup alone88 89.

All of these chemicals are toxic and a threat to both the farmers who apply them and the people and livestock that eat the produce. This is the case even for Roundup, which has been shown to have a range of damaging cellular effects indicating toxicity at levels similar to those found on crops engineered to be resistant to the herbicide90.

A Canadian government study in 2001 showed that after just 4-5 years of commercial growing, herbicide-resistant GM oilseed rape (canola) had cross-pollinated to create �superweeds� resistant to up to three different broadspectrum herbicides. These superweeds have become a serious problem for farmers both within91 92 and outside their fields93.

In addition, GM oilseed rape has also been found to crosspollinate with and pass on its herbicide resistant genes to related wild plants, for example, charlock and wild radish/turnip. This raises the possibility that these too may become superweeds and difficult for farmers to control94. The industry�s response has been to recommend use of higher amounts and complex mixtures of herbicides95 96 and to start developing crops resistant to additional or multiple herbicides. These developments are clearly creating a chemical treadmill that would be especially undesirable for farmers in developing countries.

Insecticide-Producing GM Crops

Bt insecticide-producing GM crops have led to resistance in pests, resulting in rising chemical applications97 98 99.

In China and India, Bt cotton was initially effective in suppressing the boll weevil. But secondary pests, especially mirids and mealy bugs, that are highly resistant to Bt toxin, soon took its place. The farmers suffered massive crop losses and had to apply costly pesticides, wiping out their profit margins100 101 102 103. Such developments are likely to be more damaging to farmers in developing countries, who cannot afford expensive inputs.

The claim that Bt GM crops reduce pesticide use is disingenuous, since Bt crops are in themselves pesticides. Prof Gilles-Eric S�ralini of the University of Caen, France states: �Bt plants, in fact, are designed to produce toxins to repel pests. Bt brinjal (eggplant/aubergine) produces a very high quantity of 16-17mg toxin per kg. They affect animals. Unfortunately, tests to ascertain their effect on humans have not been conducted.�104

GM Crops & Wildlife

Farm-scale trials sponsored by the UK government showed that the growing of herbicide-resistant GM crops (sugar beet, oilseed rape) can reduce wildlife populations105 106.

The Case Of Argentina

In Argentina, the massive conversion of agriculture to GM soya production has had disastrous effects on rural social and economic structures. It has damaged food security and caused a range of environmental problems, including the spread of herbicide-resistant weeds, soil depletion, and increased pests and diseases107 108.

GM Crops, Non-Target Insects & Organisms

Bt insecticide-producing GM crops harm non-target insect populations, including butterflies109 110 111 and beneficial pest predators112. Bt insecticide released from GM crops can also be toxic to water life113 and soil organisms114. One study reveals more negative than positive impacts on beneficial insects from GM Bt insecticide-producing crops.115

Can GM & Non-GM Crops Co-Exist?

The biotech industry argues that farmers should be able to choose to plant GM crops if they wish. It says GM and non-GM crops can peacefully �co-exist�. But experience in North America has shown that �coexistence� of GM and non-GM crops rapidly results in widespread contamination of non-GM crops.

This not only has significant agroecological effects, but also serious economic effects, damaging the ability of organic farmers to receive premiums, and blocking export markets to countries that have strict regulations regarding GM contamination.

Contamination occurs through cross-pollination, spread of GM seed by farm machinery, and inadvertent mixing during storage. The entry of GM crops into a country removes choice � everyone is gradually forced to grow GM crops or to have their non-GM crop contaminated.

Here are a few examples of GM contamination incidents:

� In 2006 GM rice grown for only one year in field trials was found to have widely contaminated the US rice supply and seed stocks116. Contaminated rice was found as far away as Africa, Europe, and Central America. In March 2007 Reuters reported that US rice export sales were down by around 20 percent from those of the previous year as a result of the GM contamination117.

� In Canada, contamination from GM oilseed rape has made it virtually impossible to cultivate organic, nonGM oilseed rape118

� US courts reversed the approval of GM alfalfa because it threatened the existence of non-GM alfalfa through cross-pollination119

� Organic maize production in Spain has dropped significantly as the acreage of GM maize production has increased, because of cross-pollination problems120

� In 2009, the Canadian flax seed export market to Europe collapsed following the discovery of widespread contamination with an unauthorized GM variety121.

� In 2007 alone, there were 39 new instances of GM contamination in 23 countries, and 216 incidents have been reported since 2005122.

Alternatives To GM

Many authoritative sources, including the IAASTD report on the future of agriculture123, have found that GM crops have little to offer global agriculture and the challenges of poverty, hunger and climate change, because better alternatives are available. These go by many names, including integrated pest management (IPM), organic, sustainable, low-input, non-chemical pest management (NPM) and agroecological farming, but extend beyond the boundaries of any particular category. Projects employing these sustainable strategies in the developing world have produced dramatic increases in yields and food security124 125 126 127 128 129.

Strategies employed include:

� Sustainable, low-input, energy-saving practices that conserve and build soil, conserve water, and enhance natural pest resistance and resilience in crops

� Innovative farming methods that minimize or eliminate costly chemical pesticides and fertilizers

� Use of thousands of traditional varieties of each major food crop, which are naturally adapted to stresses such as drought, heat, harsh weather conditions, flooding, salinity, poor soil, and pests and diseases130

� Use of existing crops and their wild relatives in traditional breeding programs to develop varieties with useful traits

� Programs that enable farmers to cooperatively preserve and improve traditional seeds

� Use of beneficial and holistic aspects of modern biotechnology, such as Marker Assisted Selection (MAS), which uses the latest genetic knowledge to speed up traditional breeding131. Unlike GM technology, MAS can safely produce new varieties of crops with valuable, genetically complex properties such as enhanced nutrition, taste, yield potential, resistance to pests and diseases, and tolerance to drought, heat, salinity, and flooding132.

Organic & Low-Input Methods Improve Yields In Africa

There seems little reason to gamble with the livelihoods of poor farmers by persuading them to grow experimental GM crops when tried-and-tested, inexpensive methods of increasing food production are readily available. Several recent studies have shown that low-input methods such as organic can dramatically improve yields in African countries, along with other benefits. Such methods have the advantage of being knowledge-based rather than costly input-based. As a result they are more accessible to poor farmers than the more expensive technologies (which often have not helped in the past).

A 2008 United Nations report, �Organic Agriculture and Food Security in Africa�, looked at 114 farming projects in 24 African countries and found that organic or near-organic practices resulted in a yield increase of more than 100 percent. In East Africa, a yield increase of 128 percent was found.133 The Foreword to the study states: �The evidence presented in this study supports the argument that organic agriculture can be more conducive to food security in Africa than most conventional production systems, and that it is more likely to be sustainable in the long term.�134

Organic & Low-Input Methods Improve Farmer Incomes In Developing Countries

Poverty is a major contributory factor to food insecurity. According to the 2008 United Nations report, �Organic Agriculture and Food Security in Africa�, organic farming has a positive impact on poverty in a variety of ways. Farmers benefit from:

� cash savings, as organic farming does not require costly pesticides and fertilizers;

� extra incomes gained by selling the surplus produce (resulting from the change to organic);

� premium prices for certified organic produce, obtained primarily in Africa for export but also for domestic markets; and

� added value to organic products through processing activities.

These findings are backed up by studies from Asia and Latin America that concluded that organic farming can reduce poverty in an environmentally friendly way.135

A recent study found that certified organic farms involved in production for export were significantly more profitable than those involved in conventional production (in terms of net farm income earnings).136 Of these cases, 87 per cent showed increases in farmer and household incomes as a result of becoming organic, which contributed to reducing poverty levels and to increasing regional food security.

Who Owns The Technology?

In considering which agricultural technologies will most benefit the developing world, it is crucial to ask who owns those technologies. The �Gene Revolution� that is proposed for Africa will be rolled out via public-private partnerships. The public side of such partnerships will be provided by Africa, whereas the private side will be provided by biotechnology companies based in the United States and Europe.

The transgenes used in creating GM crops are patented and owned by biotech companies. In the United States and Canada, companies have launched lawsuits against farmers whose crops were alleged to contain a company�s patented GM genes. Farmers� claims that they have not intentionally planted GM crops have proved no defense in court against large fines being imposed.

When farmers buy GM seed, they sign a technology agreement promising not to save and replant seed. They have to buy new seed each year from the biotech company, thus transferring control of food production from farmers to seed companies. Consolidation of the seed industry increasingly means that farmers have little choice but to buy GM seed. Centuries of farmer knowledge that went into creating locally adapted and varied seed stocks are wiped out.

In contrast, low-input and organic farming methods do not involve patented technologies. Control of food production remains in the hands of farmers, keeping farmer skills alive and favoring food security.

Conclusion

GM crop technologies do not offer significant benefits. On the contrary, they present risks to human and animal health, the environment, farmers, food security, and export markets. There is no convincing reason to take such risks with the livelihoods of farmers when proven successful and widely acceptable alternatives are readily and cheaply available. These alternatives will maintain the independence of the food supply from foreign multinational control and offer the best insurance against the challenges of climate change.

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Common Leading Causes Behind Hypertension | Wellness Clinic

Common Leading Causes Behind Hypertension | Wellness Clinic

Cardiovascular disease,�also called heart disease, involves numerous issues,�including diseased vessels, structural problems, and blood clots. High blood pressure, or hypertension, occurs when your blood pressure increases to unhealthy levels. Your blood pressure measurement takes into account how quickly blood is passing through your veins and the amount of resistance the blood meets while it’s pumping.

 

What are the leading causes of cardiovascular disease and hypertension?

 

Oxidative stress, inflammation and autoimmune dysfunction initiate and propagate hypertension and cardiovascular disease.�In a series of research studies correlated to cardiovascular disease and hypertension, Dr. Mark C. Houston, MD, discussed the role that oxidative stress, inflammation and autoimmune dysfunction plays in relation to treatment of hypertension and cardiovascular disease.

Oxidative Stress

 

Oxidative stress, with an imbalance between the defense mechanisms and RNS as well as ROS, contributes to the etiology of hypertension in humans and animals. Radical oxygen species and RNS are generated by numerous mobile sources, such as nicotinamide adenine dinucleotide phosphate hydrase (NADPH) oxidase, mitochondria, xanthine oxidase, uncoupled endothelium-derived nitric oxide (NO) synthase (U-eNOS), cyclo-oxygenase and lipo-oxygenase. Superoxide anion is your predominant ROS species produced with these tissues, which inhibits NO and also leads to downstream production of additional ROS (As seen in Figure 3).

 

Vascular Endothelium

 

Patients have impaired an oxidative stress reaction to several stimuli, an elevated plasma oxidative stress and exogenous and endogenous antioxidant defense mechanisms. Hypertensive subjects also have lower plasma ferric reducing ability of plasma vitamin C levels and increased plasma 8-isoprostanes, which correlate with both diastolic and systolic BP. Different single-nucleotide polymorphisms (SNP’s) in genes that codify for antioxidant enzymes are directly linked to hypertension. These include NADPH oxidase, xanthine oxidase, superoxide dismutase 3 (SOD 3), catalase, glutathione peroxidase 1 (GPx 1) and thioredoxin. Antioxidant deficiency and excess free radical production have been implicated in human hypertension in several epidemiologic, observational and interventional studies (Table 2).

 

Table 2 Infographic

 

Radical oxygen species directly damage endothelial cells, degrade NO, influence eicosanoid metabolism, oxidize LDL, lipids, proteins, proteins, DNA and natural molecules, boost catecholamines, harm the genetic machinery, affect gene expression and transcription factors. The interrelations of systems, oxidative stress and cardiovascular disease are shown in Figures 6 and 7. The increased oxidative stress, inflammation and autoimmune vascular dysfunction in human hypertension results in a combination of an response to ROS and RNS increased generation of ROS and RNS and a decreased antioxidant reserve. Increased oxidative stress from the rostral ventrolateral medulla (RVLM) enhances glutamatergic excitatory inputs and attenuates GABA-ergic inhibitory inputs into the RVLM which contributes to increased sympathetic nervous system (SNS) activity from the paraventricular nucleus. Activation of this AT1R in the RVLM raises NADPH oxidase and increases oxidative stress and superoxide anion, increases SNS outflow causing an imbalance of SNS/PNS action with elevation of BP, increased heartbeat and alterations in heart rate variability and heart rate recovery time, which can be obstructed by AT1R blockers.

 

Endothelium-Dependent Responses

 

Neurohormonal and Oxidative Stress System Interaction

 

Inflammation

 

The link between hypertension and inflammation was suggested in both longitudinal and cross-sectional studies. Raised in high sensitivity C-reactive protein (HS-CRP) and other inflammatory cytokines such as interleukin-1B, (IL-1B), IL-6, tumor necrosis alpha (TNF-?) and chronic leukocytosis occur in hypertension and hypertensive-related TOD, such as increased carotid IMT. HS-CRP predicts CV events. Elevated HS-CRP is risk factor and a risk marker for hypertension and CVD. Increases in HS-CRP of over 3 ?g/mL can increase BP in only a couple of days that is directly proportional to the increase in HS-CRP. ENOS and nitric oxide are inhibited by HS-CRP. HS-CRP, down-regulates the AT2R, that counterbalances AT1R. Angiotensin II (A-II) upregulates many of those cytokines, notably IL-6, CAMs and chemokines by activating nuclear factor Kappa B (NF-?B) resulting in vasoconstriction. These events, as well as the increases in endothelin-1 and oxidative stress, elevate BP.

 

Autoimmune Dysfunction

 

Innate and adaptive immune responses are associated with hypertension and hypertension-induced CVD through at least three mechanisms: central nervous system stimulation cytokine generation and renal impairment. This includes salt-sensitive hypertension with dysregulation of both CD4+ and CD8+ lymphocytes increased inflammation because of T cell imbalance and chronic leukocytosis with increased neutrophils and lymphocytes that are decreased. Leukocytosis, especially neutrophils and decreased lymphocyte count raise BP in Blacks by. Macrophages and invade the wall, trigger TLRs, various subtypes govern BP and cause autoimmune vascular damage. Angiotensin II activates immune cells (T cells, macrophages and dendritic cells) and promotes cell infiltration into target organs. CD4+ T lymphocytes express AT1R and PPAR gamma receptors, and release TNF-?, interferon and interleukins inside the vascular wall when triggered (Figure 5). May play a role in the genesis of hypertension brought on by Angiotensin II. Patients have higher TLR 4 mRNA in monocytes in comparison to normal. Intensive decrease in BP to systolic BP (SBP) less than 130 mmHg vs SBP to just 140 mmHg reduces the TLR 4 longer. A-II activates the TLR expression resulting in inflammation and activation of the innate immune system. When TLR 4 is triggered there is downstream macrophage activation, increase metalloproteinase 9, migration, vascular remodeling, collagen accumulation in LVH the gut and cardiac fibrosis. The autonomic nervous system is essential in either increasing or decreasing inflammation and immune dysfunction. Efferent cholinergic pathways through the nerve innervate the spleen, nicotine acetylcholine receptor subunits and cytokine producing immune cells to BP and affect vasoconstriction. Nearby CNS inflammation or ischemia may mediate vascular hypertension and inflammation.

 

Aldosterone is correlated with increased adaptive immunity and autoimmune responses with CD4+ T cell activation and Th 17 polarization with improved IL 17, TGF-? and TNF-? which modulate over 30 inflammatory genes. Serum aldosterone is also an independent risk factor for CVD and CHD via non-hemodynamic effects as well as through increased BP. Blockade of receptors in brain, the heart, blood vessels and immune cells reduces CV danger even with the persistence of hypertension.

 

In conclusion, cardiovascular disease and hypertension have been associated with numerous issues, however, oxidative stress, inflammation and autoimmune dysfunction have been regarded as the most prevalent causes behind cardiovascular disease and hypertension.�Oxidative stress, defined as a disturbance in the balance between the production of reactive oxygen species (free radicals) and antioxidant defenses, inflammation and autoimmune dysfunction, occurs�when the body’s immune system attacks and destroys healthy body tissue by mistake. Cardiovascular disease and hypertension is an indication of cardiovascular issues which should be addressed by a healthcare professional.

 

The scope of our information is limited to chiropractic and spinal injuries and conditions. To discuss options on the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .�Green-Call-Now-Button-24H-150x150-2.png

 

By Dr. Alex Jimenez

 

Additional Topics: Wellness

 

Overall health and wellness are essential towards maintaining the proper mental and physical balance in the body. From eating a balanced nutrition as well as exercising and participating in physical activities, to sleeping a healthy amount of time on a regular basis, following the best health and wellness tips can ultimately help maintain overall well-being. Eating plenty of fruits and vegetables can go a long way towards helping people become healthy.

 

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The Connection Between Leaky Gut & Diabetes | Wellness Clinic

The Connection Between Leaky Gut & Diabetes | Wellness Clinic

Many people with diabetes are extremely conscious about their health, for this reason, they are continuously looking for ways to handle their diabetes more efficiently. However,how can they make a difference if they do not even understand the disease they are currently suffering from? Some factors are thought to cause this and make it even worse.

 

Leaky gut is one of those ailments; some also theorize that without a leaky gut, you can’t actually have type 2 diabetes. Not only could it cause diabetes, but it may perpetually make it even worse.

 

What is Leaky Gut?

 

Leaky gut can be called “intestinal hyperpermeability”. In simpler terms, it means that toxins on your gut may pass through the intestines and also leak in your entire body. As can be anticipated, this causes lots of medical problems.

 

Basically, leaky gut occurs when your digestive tract is weak in the poor diet, among other factors. The intestines worn and are currently thinning down. The “good bacteria” which assist you in breaking down your food and eliminating toxins are not flourishing. Leaky gut allows toxins to reside in the body which should have been expelled quite quickly, causing symptoms such as these:

 

  • Inflammation (sometimes severe)
  • Inflammatory bowel disease (Crohn and ulcerative colitis)
  • Irritable bowel syndrome
  • Food allergies
  • Chronic fatigue
  • Hepatitis
  • Pancreatitis
  • Arthritis
  • Diarrhea
  • Joint pain
  • Skin rash
  • Diabetes
  • AIDS

 

With such a lengthy list of conditions related to your leaky gut, you might begin to think it is a super-disease or something. Do not worry, it is not. Though it contributes to or causes some messed up stuff inside your body, it’s avoidable and even reversible. Some professionals even believe you could reverse severe and chronic disease (such as diabetes) by preventing that leaky gut.

 

You won’t discover much about leaky gut from mainstream physicians. Most doctors do not even test this yet. It is really somewhat of a mystery to most medical professionals. Linda A. Lee, MD, a gastroenterologist in John Hopkins Integrative Medicine and Digestive Center says “We do not understand a good deal, but we know that it exists.” She proceeds. “In the absence of evidence, we do not know… what treatments may directly address it.”

 

Other specialists, such as Donald Kirby, MD, refer to a leaky gut as a “very grey area”. Itself is a diagnosis of a disorder, it means that more research needs to be done, and an individualized diagnosis has to be made. What exactly does that mean? It usually means that the root of leaky gut can be any number of items, so you want to discover the cause. On this note, let’s take a look at some of these triggers.

 

What Causes Leaky Gut?

 

To reiterate, there isn’t any one conclusive cause due to the shortage of research done. However, there are a number of items upon this could give rise to your intestines getting weak, ineffective, and leaky agreed. These include:

 

  • Excessive alcohol usage (which can irritate the intestinal wall)
  • A poor diet (we will talk about this more)
  • Chemotherapy
  • Gluten
  • Stress
  • Antibiotics
  • Prescription hormone medicine
  • Prescription corticosteroids (like hydrocortisone)
  • Enzyme deficiency (like having lactose-intolerance)
  • Toxic metals
  • Aspirin, ibuprofen, and other anti-inflammatory drugs
  • Chemotherapy and radiation therapy

 

Your gut has a great deal of difficult work to do. Not only does it need to digest and break it down into nutrients to nourish your body, in addition, it has to guard you from toxins which would otherwise put in your bloodstream and of the waste products. This heavy responsibility warrants that we take care of our bowels. Unfortunately, the greater bulk of people today don’t even give a second thought.

 

Your typical American diet is filled with sugary soft drinks, white flour, and otherwise high tech, low-fiber foods. This leads to an unhealthy gut in which germs are useless and weak while bacteria flourish and harm your intestines. The walls of your intestines begin to neglect when the damage is too severe. They become permeable and start to permit the toxins and waste, so which was intended to remain right into your bloodstream.

 

Some of those other items on the above list, such as alcohol and some prescription and over-the-counter medications, also have a negative effect on the internal flora of your intestines. You have a harder time fighting the things that pass through it and digesting your food if the good bacteria is killed off in your gut. Your gut can begin to leak and becomes unhealthy as the good bacteria make way for bacteria.

 

How Exactly is Leaky Gut Connected to Diabetes?

 

To provide you the most shocking news first: new study suggests that you can have each of the genetic predispositions to diabetes in the world, however you’ll never really contract diabetes unless you’ve got a leaky gut also. This means (if this study is correct) for those who have diabetes, then you already have a leaky gut.

 

The largest link between migraines, leaky gut and diabetes is inflammation. Inflammation is involved with developing type 2 diabetes. In fact, many disorders are associated with inflammation such as:

 

  • Periodontal disease
  • Stroke
  • Heart disease
  • Insulin resistance and Type 2 diabetes

 

When toxins leak from your intestines and in your bloodstream, this causes an immune response from the human body. The modest cells that your body sends out do their best to remove toxins and the bacteria from inducing damage than inflammation could ever cause. Unfortunately, that’s just what happens. The war against germs waged by your immune system induces a whole lot of inflammation.

 

Continuous abnormal inflammation (like that caused by a leaky gut) changes your natural insulin levels and actions, contributing to diabetes. You eventually form, once your body starts to become insensitive to insulin. You are able to see the cycle here. The more inflammation. The more inflammation, the insulin resistance. If you add that on top of a continuously leaky gut isn’t far off.

 

Inflammation causing insulin resistance has been observed by Mario Kratz, Ph.D., in experiments involving mice also. Some of the mice were fat, which caused a constant inflammation. Insulin resistance was developed by the mice with this inflammation. This left the question: was it that the inflammation, or Was the fat causing the insulin resistance? To answer this question, scientists bred mice that lacked the ability to generate certain immune responses that cause inflammation. Then they proceeded to feed. What was the result? These mice didn’t have insulin resistance. What does this mean? It usually means that the insulin resistance came in the inflammation, not the fat cells themselves. This supports researcher’s claims that diabetes is contributed to by inflammation caused by a leaky gut.

 

Another experiment conducted on mice in 2012 took a different approach. The mice were given a drug called Tamoxifen to simulate bad gut feature, ruin their inner ecology and kill healthy bacteria. The researchers found similarities between the bowels of mice with mice and diabetes whose guts were ruined with Tamoxifen. The two groups of mice enhanced, when given insulin. To the scientists, this demonstrated that diabetes is strongly associated with gut health.

 

To outline, scientists do not know everything about leaky gut and how it results in diabetes, but they are starting to learn more. There is certainly more research but it is apparent that an unhealthy gut doesn’t only have an effect on digestion, but can have side effects for the health of the body.

 

How Would I Know if I Have a Leaky Gut?

 

The very first thing you might do is refer back to the indicators of a leaky gut which we already laid out for you (things such as skin rashes, joint pain, nausea, chronic fatigue, and IBS), but that might not help you as much as you’d believe. The potential symptoms includes side effects of another list of distinct ailments that have nothing to do with a leaky gut.

 

Some other things you can look at would be things such as:

 

Food Sensitivity

 

When radicals are continuously leaking into your blood due to a leaky gut, your body is overproducing trigger-happy antibodies, and those antibodies start to attack things which they would not normally. This causes food sensitivity, particularly to milk and gluten.

 

Malabsorption

 

As you can imagine, people with a degenerative digestive tract that’s leaking, also have difficulty absorbing nutrients. This can become evident through side-effects like fatigue.

 

Thyroid Issues

 

Leaky gut can directly contribute to chronic thyroiditis. This also leads to slow metabolism, constipation, chronic fatigue, and depression.

 

Tests To Identify & Diagnose Leaky Gut

 

It is difficult to link some other symptom straight with leaky gut due to the fact that the symptoms might be the result of almost anything else. There are a few tests that you could do in order to see whether you’ve got it. Here are some tests which could be done to identify leaky gut:

 

Lactulose/Mannitol test

 

This test involves drinking a sugary solution. A urine sample tested and is removed. If lactulose and mannitol are present, it could suggest a leaky gut.

 

Stool Evaluation

 

An expensive test that assesses for bacteria and yeast to see if your gut is infected. This evaluation isn’t likely to be covered by your insurance.

 

What Can I do to Prevent or Cure Leaky Gut?

 

We have to keep in mind the germs that reside inside your body make up a very important ecosystem that keeps your digestive tract healthy. So let us start thinking about how we could make that job easier, or at least enjoyable your intestines have a job.

 

Since we have mentioned several times by now, leaky gut has a lot to do with your internal germs or intestine flora. Minimize bacteria and you want to maximize the amount of bacteria that are good. This may be done through diet and exercise. It sounds simple, but there is more to it in this circumstance.

 

What sort of diet do you really require?

 

When it comes to diet, it takes more than a simple “eat healthier!” Recommendation to fight an already leaky gut. You have to imagine that your bacteria is entirely dead. To counteract your useless gut flora, you ought to think about “re-seeding” it using healthy bacteria from your diet plan. You can accomplish so by eating probiotic foods like “lassi” (a noodle drink), fermented vegetables like kimchi, or other probiotic foods such as sauerkraut, miso, or kombucha (locate a listing of probiotic foods here).

 

One more thing you can do is eat naturally anti-inflammatory foods to counteract the side-effects of leaky gut. Some of those foods are things like avocados, walnuts, healthy fats (such as omega-3 fatty acids), and olive oil (find out more about anti-inflammatory foods here).

 

Once you get started ingesting foods which will combat a leaky gut such as those mentioned previously, it is time to stop eating foods that give rise to inflammation. These foods are things such as red meat, fried foods (such as french fries — sorry!) , refined carbs (think white bread), margarine, cheese (as well as other calcium-rich dairies). These foods aren’t easy in your gut flora and tend to increase inflammation in the body.

 

It would also be a good idea to avoid any trans fats, and sugary foods altogether. Refined sugar contributes. In light of diabetes, anything to help improve insulin levels and a leaky gut ought to be considered.

 

As a review, you should replace as many processed foods as possible with organic possibilities, re-seed your gut with good bacteria by eating fermented foods, and avoid foods that give rise to inflammation or insulin resistance.

 

What about supplements and medications?

 

There are particular things that may be taken orally that affect your gut flora at a positive or a negative manner that isn’t necessarily considered a portion of your diet. So let’s talk about drugs and nutritional supplements.

 

You will find nutritional supplements you may take in the kind of probiotics. This certainly can help improve your digestive tract function by maintaining a healthy gut flora. Probiotics give a large dose of one type of bacteria to you for your intestines that promote good digestion, absorption, and inflammation.

 

On the other hand, there are lots of drugs that harm your gut flora. Taking antibiotics may be necessary when you’re sick, but don’t overuse them in pill form or perhaps in antibacterial soap. Over just bacteria are killed by antibiotics, they kill the bacteria that are good as well.

 

Other substances you might encounter that you may not think about are things like chlorinated water, agricultural chemicals located on non-toxic vegetables and fruits, and traces of antibiotics located in factory-farmed meat might also harm your internal flora.

 

In Overview: Key Takeaway

 

Leaky gut definitely results in, and potentially causes diabetes alongside any number of different illnesses. Thankfully, it is avoidable and curable; thus look after your intestines. If you eat healthy, exercise, and maintain your inner flora, you will be thanked by your gut personally, and you can potentially get an upper hand or even avoid it altogether.

 

The scope of our information is limited to chiropractic and spinal injuries and conditions. To discuss options on the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .�
 

By Dr. Alex Jimenez

 

Additional Topics: Wellness

 

Overall health and wellness are essential towards maintaining the proper mental and physical balance in the body. From eating a balanced nutrition as well as exercising and participating in physical activities, to sleeping a healthy amount of time on a regular basis, following the best health and wellness tips can ultimately help maintain overall well-being. Eating plenty of fruits and vegetables can go a long way towards helping people become healthy.

 

blog picture of cartoon paperboy big news

 

TRENDING TOPIC: EXTRA EXTRA: About Chiropractic

 

 

Too Much Exercise Harms GI Function: Study

Too Much Exercise Harms GI Function: Study

When it comes to stomach discomfort during exercise, forget that old adage “no pain, no gain.” New research suggests that excessive strenuous exercise may lead to gut damage.

“The stress response of prolonged vigorous exercise shuts down gut function,” said lead author Ricardo Costa.

“The redistribution of blood flow away from the gut and towards working muscles creates gut cell injury that may lead to cell death, leaky gut, and systemic immune responses due to intestinal bacteria entering general circulation,” Costa added. He’s a senior researcher with the department of nutrition, dietetics and food at Monash University in Australia.

Researchers observed that the risk of gut injury and impaired function seems to increase along with the intensity and duration of exercise.

The problem is dubbed “exercise-induced gastrointestinal syndrome.” The researchers reviewed eight previously done studies that looked at this issue.

Two hours appears to be the threshold, the researchers said. After two hours of continuous endurance exercise when 60 percent of an individual’s maximum intensity level is reached, gut damage may occur. Costa said that examples of such exercise are running and cycling.

He said heat stress appears to be an exacerbating factor. People with a predisposition to gut diseases or disorders may be more susceptible to such exercise-related health problems, he added.

Dr. Elena Ivanina is a senior gastroenterology fellow at Lenox Hill Hospital in New York City. She wasn’t involved with this research but reviewed the study. She said that normal blood flow to the gut keeps cells oxygenated and healthy to ensure appropriate metabolism and function.

If the gut loses a significant supply of blood during exercise, it can lead to inflammation that damages the protective gut lining. With a weakened gastrointestinal (GI) immune system, toxins in the gut can leak out into the systemic circulation — the so-called “leaky gut” phenomenon, Ivanina said.

But, she underscored that exercise in moderation has been shown to have many protective benefits to the gut.

“Specifically, through exercise, patients can maintain a healthy weight and avoid the consequences of obesity,” she said. Obesity has been associated with many GI diseases, such as gallbladder disease; fatty liver disease; gastroesophageal reflux disease (GERD); and cancer of the esophagus, stomach, liver and colon. Regular moderate physical activity also lowers the risk of cardiovascular disease, type 2 diabetes and depression.

To prevent exercise-related gut problems, Costa advised maintaining hydration throughout physical activity, and possibly consuming small amounts of carbohydrates and protein before and during exercise.

Ivanina said preventive measures might help keep abdominal troubles in check. These include resting and drinking enough water. She also suggested discussing any symptoms with a doctor to ensure there is no underlying gastrointestinal disorder.

Costa recommended that people exercise within their comfort zone. If you have stomach or abdominal pain, “this is a sign that something is not right,” he said.

Individuals with symptoms of gut disturbances during exercise should see their doctor.

The study authors advised against taking nonsteroidal anti-inflammatory drugs — including ibuprofen (Advil, Motrin) or naproxen sodium (Aleve) — before working out.

Costa said there’s emerging evidence that a special diet — called a low FODMAP diet — leading up to heavy training and competition may reduce gut symptoms. FODMAP stands for fermentable oligosaccharides, disaccharides, monosaccharides, and polyols. FODMAPs are specific types of carbohydrates (sugars) that pull water into the intestinal tract.

The International Foundation for Functional Gastrointestinal Disorders suggests consulting a dietitian familiar with FODMAP diets. Such diets can be difficult to initiate properly on your own, the foundation says.

Costa also said there’s no clear evidence that dietary supplements — such as antioxidants, glutamine, bovine colostrum and/or probiotics — prevent or reduce exercise-associated gut disturbances.

The study results were published online recently in the journal Alimentary Pharmacology & Therapeutics.

How Gut Problems Induce Joint Ache

How Gut Problems Induce Joint Ache

Hippocrates, the father of modern medicine, stated all healing starts in the gut. And researchers carry on to prove him accurate as they unravel how a healthier gut microbiome plays a function in fat decline, disease prevention, and much additional. As we know, diet plays a very important function in keeping a healthier gut setting and dysbiosis, or a gut-flora imbalance, ramps up inflammation, and triggers lots of diseases like inflammatory bowel disease.

As a health practitioner of chiropractic, gut health gives insight into why my clients (in particular overweight or overweight clients) establish osteoarthritis in non-fat-bearing joints like the wrist, by pointing to a difficulty with systemic inflammation. And when my clients have an understanding of how an out-of-whack gut impacts digestion, they do not generally make the link concerning gut health and joint agony or other issues like head aches, mood swings, eczema, fat acquire, or tiredness that frequently accompany agony.

Gut issues can trigger agony.

How does this perform? To start with, consider that truth that your gut maintains a reliable barrier concerning your digestive tract and your inside setting, enabling important vitamins to go by when preserving out anything else. Retaining the integrity of the gut is a a person-cell-thick barrier that varieties a limited junction, which keeps out foreign invaders like bacteria, poisons, and big undigested foods particles. When these limited junctions crack down, that barrier will become infected and porous bacteria, poisons, and undigested foods particles start off slipping by. We connect with these foreign invaders antigens, or foreign substances that trigger an immune response. A double whammy ensues: You are not finding optimal vitamins when foreign invaders barge by, a problem termed intestinal permeability or leaky gut.

This link has anything to do with inflammation.

Your immune program responds with antibodies, which assault and ruin these antigens. When an antibody binds with an antigen, an immune advanced happens. Persistent leaky gut ramps up these immune complexes they flow into all-around your entire body and deposit into several tissues and organs including�you guessed it�skeletal muscle tissues and joints, creating additional inflammation. Leaky gut also contributes to autoimmune conditions, or immune responses towards unique tissues that develop destruction and decline of functionality. When that takes place in your joints, inflammation makes agony, inflammation, and stiffness. When multifactorial, researchers link leaky gut with rheumatoid arthritis as bacterial merchandise slip by your gut lining and deposit in your joints, creating an immune reaction.

You can lessen agony by healing the gut.

When my clients recover their leaky gut, they lastly set out the fireplace that feeds inflammation. That healing calms their immune program, reverses autoimmune conditions like rheumatoid arthritis, and decreases agony. And you can do this in a natural way without the need of medicine or surgical treatment. Further than concentrating on a entire-food items diet that gets rid of foods intolerances, I�ve located these 7 tactics to improve gut health to reverse agony:

1. Stage up your fiber.

Studies display that enough dietary fiber could possibly be your greatest technique to keep a healthier microbiome. Amid its benefits, fiber aids pull poisons from your gut for elimination.

2. Take in additional anti-inflammatory food items.

Omega-three fatty acids have anti-inflammatory qualities and aid alleviate agony. If wild-caught fish isn�t aspect of your diet, just take a large-high quality fish oil nutritional supplement with about three,000 milligrams of EPA and DHA.

three. Repopulate smartly.

Probiotics aid re-set up a balanced gut microbiome. Fermented food items like coconut yogurt, kefir, and sauerkraut are great sources of probiotics, but if you do not on a regular basis consume them, appear for a professional multistrain probiotic nutritional supplement with billions of microorganisms.

4. Get enough vitamin D.

Scientists link vitamin D deficiencies with several issues like inflammation, leaky gut, and autoimmune conditions like rheumatoid arthritis and chronic agony. Request your health practitioner for a twenty five-hydroxy vitamin D take a look at and perform with him or her to attain and keep optimal ranges.

5. Ditch the gluten.

If you have joint agony or other sorts of agony, gluten�s gotta go. Gliadin is the protein located in wheat, rye, and barley lots of men and women are delicate to or that leads to an outright autoimmune reaction. Your immune program sees gluten as the enemy and will unleash weapons to assault it, triggering inflammation in your gut, joints, and other regions of the entire body.

6. Avoid GMOs.

Eradicating genetically modified food items (GMOs) will become very important for healing your leaky gut considering the fact that GMOs destruction your digestive tract and may possibly be a person of the leads to of your leaky gut in the initial place.

7. Nix nightshades.

Colourful bell peppers, tomatoes, potatoes, and eggplants supply vitamins and phytonutrients, but they can be a difficulty for clients with leaky gut, autoimmune disease, or osteoarthritis. Nightshades incorporate glycoalkyloids, which can develop gut issues.

Gut Bacteria Hold Key to Diagnosing, Treating Chronic Fatigue

Gut Bacteria Hold Key to Diagnosing, Treating Chronic Fatigue

Chronic fatigue syndrome, a baffling disorder that affects an estimated 1 million Americans, has been strongly linked to imbalances in gut bacteria in a new study from Columbia University’s Mailman School of Public Health.

The researchers found abnormal levels of specific gut bacteria are found in people with the condition — formally known as myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS), according to the study published in the journal Microbiome.

The findings offer new hope for an effective new way to diagnose and treat ME/CFS, a complex, sometimes-debilitating disorder that can interfere with activities of daily living.

Symptoms include extreme fatigue after exertion, muscle and joint pain, cognitive dysfunction, sleep disturbances, and orthostatic intolerance (light-headedness, dizziness, or fainting when standing upright).

Up to 90 percent of ME/CFS patients also have irritable bowel syndrome IBS, past research has shown. But the Columbia University study is among the first to disentangle microbiome imbalances in individuals with ME/CFS and IBS.

“Individuals with ME/CFS have a distinct mix of gut bacteria and related metabolic disturbances that may influence the severity of their disease,” says co-lead investigator Dr. Dorottya Nagy-Szakal.

The findings suggest sufferers may be able to ease their symptoms by incorporating certain probiotics — healthy bacteria — in their diets, to balance their gut bacteria.

To reach their conclusions, the researchers tracked 50 ME/CFS patients and 50 others without the condition. They tested subjects’ fecal samples for bacterial species, and blood samples for immune molecules.

The study’s key findings show that:

  • Levels of distinct intestinal bacterial species —Faecalibacterium, Roseburia, Dorea, Coprococcus, Clostridium, Ruminococcus, Coprobacillus — are strongly associated with ME/CFS.
  • The abundance of these species appears to be predictive of a ME/CFS diagnosis.
  • An abundance of Alistipes and low levels of Faecalibacterium are the top biomarkers of ME/CFS with IBS. Increased Bacteroides abundance and decreased Bacteroides vulgatus are the top biomarkers of ME/CFS without IBS.

The researchers also noted the severity of patients’ symptoms — such as pain and fatigue — correlated with the abundance of distinct bacterial types.

“Our analysis suggests that we may be able to subtype patients with ME/CFS by analyzing their fecal microbiome,” says co-lead investigator Dr. Brent L. Williams, Ph.D. “Subtyping may provide clues to understanding differences in manifestations of disease.”

The study also points toward a possible mechanism behind the development of ME/CFS.

“ME/CFS may involve a breakdown in the bidirectional communication between the brain and the gut mediated by bacteria, their metabolites, and the molecules they influence,” explains senior author Dr. W. Ian Lipkin.

“By identifying the specific bacteria involved, we are one step closer to more accurate diagnosis and targeted therapies.”

So far, researchers have not identified the cause of ME/CFS. Nor are there any standard diagnostic lab tests or federally-approved treatments for the condition. For reasons that are unclear, women are two to four more times likely than men to have ME/CFS.

Because MD/CFS is so variable, treatment focuses on individual symptom control. Conventional approaches include prescription medications to treat anxiety, depression, and insomnia; graded exercise, physical therapy, and psychological counseling including cognitive-behavioral therapy (CBT).

Adjunctive therapies to help manage pain and fatigue include:

  • Acupuncture.
  • Biofeedback.
  • Deep breathing exercises.
  • Hypnosis.
  • Massage.
  • Meditation.
  • Muscle relaxation techniques.
  • Yoga or tai chi.
  • Preliminary but inconclusive research suggests that some natural remedies may be helpful for ME/CFS, according to the Mayo Clinic. These include:
  • Magnesium injected into the muscles of people with low red blood cell magnesium.
  • A combination supplement containing fish oil and evening primrose oil.
  • Melatonin.
  • Nicotinamide.
  • Adenine dinucleotide hydrate (NADH).
  • Coenzyme Q10.
  • Propionyl-L-carnitine.
  • D-ribose.

Although the new Columbia University study suggests that probiotic supplements may be helpful for ME/CFS, more research is needed, experts say.

A 2009 study of 39 ME/CFS patients, however, showed that the Lactobacillus casei strain Shirota (LcS) was associated with significantly reduced anxiety symptoms compared to placebo.