A Franco-Australian study published this week reports that testosterone protects males against developing asthma, suppressing the production of a type of immune cell that triggers allergic asthma.
An international team of researchers set out to investigate why females are two times more likely to develop asthma than males after puberty.
According to the research, carried out jointly by the Walter and Eliza Hall Institute in Melbourne, Australia, and the Physiopathology Center of Toulouse-Purpan, France, the answer could lie in our hormones.
The scientists found that high levels of testosterone had a protective effect against the development of allergic asthma, inhibiting immune cells called type-two innate lymphoid cells (ILC2), associated with the initiation of asthma.
As highlighted by a French study published in PNAS in 2014, these cells, which are found in lungs, skin and other organs, play a role in triggering allergic reactions like asthma.
These cells produce inflammatory proteins that can cause lung inflammation and damage in response to common triggers for allergic asthma, such as pollen, dust mites, cigarette smoke and pet hair.
“Testosterone directly acts on ILC2s by inhibiting their proliferation,” explains Dr Cyril Seillet from Melbourne’s Walter and Eliza Hall Institute. “So in males, you have less ILC2s in the lungs and this directly correlates with the reduced severity of asthma.”
This major breakthrough in understanding the mechanisms that drive allergic asthma, as well as key differences between males and females, could lead to new treatments for the disease. These could potentially mimic the hormonal regulation of ILC2 to treat or prevent asthma.
PUSH-as-Rx � Fitness & Athletic Training is re-writing the status quo of fitness all together.
PUSH-as-Rx �� is leading the field with laser focus supporting our youth sport programs.� The PUSH-as-Rx � System is a sport specific athletic program designed by a strength-agility coach and physiology doctor with a combined 40 years of experience working with extreme athletes. At its core, the program is the multidisciplinary study of reactive agility, body mechanics and extreme motion dynamics. Through detailed and continued assessments of the athletes in motion and under stress loads offer a clear scientific picture of body dynamics. This system also has helped many athletes come back from injury faster, stronger, and ready to safely return to their sport without losing a beat after recovery. Results demonstrate clear improved agility, speed, decreased reaction time and advantageous postural-torque mechanics.� PUSH-as-Rx � offers specialized extreme performance enhancements to our athletes no matter the age.
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PUSH Fitness & Athletic Training is pushing the barriers of average gyms. Not only do we offer training sessions on the hour every hour but we also cater to the most athletic to the elderly and obesity of populations. We are a no contract gym because we believe in you making the commitment to change your lifestyle and not forcing you to.
By blending CrossFit and Personal Training, we are able to tailor make workouts that are very specific and individualized to each member no matter where they are physically. Ultimately PUSH�ing them to feel and look their absolute best.
We don�t stop there. PUSH also offers strength and conditioning programs, which improves the athletic ability of kids and teams of any sport at any age.
PUSH-as-Rx �� is leading the field with laser focus supporting our youth sport programs.� The PUSH-as-Rx �� System is a sport specific athletic program designed by a strength-agility coach and physiology doctor with a combined 40 years of experience working with extreme athletes. At its core, the program is the multidisciplinary study of reactive agility, body mechanics and extreme motion dynamics. Through detailed and continued assessments of the athletes in motion and under stress loads offer a clear scientific picture of body dynamics. This system also has helped many athletes come back from injury faster, stronger, and ready to safely return to their sport without losing a beat after recovery. Results demonstrate clear improved agility, speed, decreased reaction time and advantageous postural-torque mechanics.� PUSH-as-Rx �� offers specialized extreme performance enhancements to our athletes no matter the age.
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Several studies have suggested that menopause may increase the risk of hearing loss, possibly due to lower estrogen levels, and that postmenopausal hormone replacement therapy might slow the decline. But researchers at Brigham and Women’s Hospital found that hormone therapy actually increased the risk of hearing loss.
Researchers examined links between menopausal status, oral hormone therapy, and risk of self-reported hearing loss in more than 80,000 women in the Nurses’ Health Study II.
During the 22-year study period, 23 percent of the participants developed hearing loss. Although no significant association was found between menopausal status and the risk, using postmenopausal hormone therapy was linked to a higher risk of hearing loss. The longer women used hormone therapy, the greater their risk.
“Our research focuses on identifying preventable contributors to hearing loss,” said lead author Dr. Sharon Curhan. “Although the role of sex hormones in hearing is complex and incompletely understood, these findings suggest that women who undergo natural menopause at an older age may have a higher risk. In addition, longer duration of postmenopausal hormone therapy use is associated with higher risk.
“These findings suggest that hearing health may be a consideration for women when evaluating the risks and benefits of hormone therapy,” she said.
The findings are published online May 10, 2017 in Menopause, The Journal of the North American Menopause Society.
An earlier study by Dr. Curhan of 65,000 women found that those who eat at least two servings of fish every week have a lower risk of age-related hearing loss.
Although hearing loss is often considered an inevitable part of aging, those who ate two or more servings a week had a 20 percent lower risk of hearing loss when compared to women who rarely ate fish. “Consumption of any type of fish tended to be associated with lower risk,” said Dr. Curhan. “These findings suggest that diet may be important in the prevention of acquired hearing loss.”
Approximately 48 million Americans suffer from hearing loss, and the number is expected to increase as the population ages.
Poor posture is an incredibly common problem in today�s world. With the increase in technology and decrease in physical exercise, many people find their posture slipping more than ever before. While we know that good posture certainly looks better, is it really cause for concern? Take a look at these ways in which poor posture may negatively impact health, followed by some tips for improving it a little more every day.
The Effects of Poor Posture
Pain in the Back, Neck, and Shoulders – Poor posture can cause stiffness or pain in any of these areas. The longer you sit or stand with bad posture, the more pronounced these pains are likely to be.
Slow Digestion – Poor posture is almost always because of slumping or slouching the shoulders and core. This can cause the digestive tract to be pressed, which can make any sort of digestion painful and more troublesome.
Poor Self Perception – Our minds often take cues from the body. If slouching is a constant, our minds get the message that we feel poorly about ourselves, and our self-esteem and perception is likely to take a hit.
Solutions for Bad Posture
Exercise – Both regular exercise as well as posture specific exercises can help strengthen the body and improve overall posture. This might include moves that especially work the core, back, and shoulders.
Find Some Triggers – Bad posture is a tough habit to break. It can help to give yourself constant reminders. Ask a friend to remind you when they see you slouching. Post sticky notes all over the mirror or your desk at work. Set intermittent alarms on your phone. Do whatever it takes to bring good posture to the forefront of your mind.
Get Chiropractic Care – This is actually a great place to start for correcting poor posture. Chiropractors can eliminate painful areas of the spine that may be contributing to poor posture. They may also help to increase flexibility, improve mobility, as well as give you some simple everyday tips for getting your posture and basic spinal health in check.
The scope of our information is limited to chiropractic and spinal injuries and conditions. To discuss options on the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .
Additional Topics: Preventing Spinal Degeneration
As we age, it’s natural for the spine, as well as the other complex structures of the spine, to begin degenerating. Without the proper care, however, the overall health and wellness of the spine can develop complications, such as degenerative disc disease, among others, which could potentially lead to back pain and other painful symptoms. Chiropractic care is a common alternative treatment option utilized to maintain and improve spine health.
Kicking the sugar habit is no easy task. But if you�re considering giving it a try, here�s some inspiration to help you succeed: it�ll have profound effects on your short- and long-term health.
A little of the sweet stuff is okay; the American Heart Association recommends consuming no more than 6 teaspoons of added sugar a day for women and 9 teaspoons daily for men. (Quick comparison: a 12-ounce can of cola has approximately 8 teaspoons.) And you can keep eating unprocessed foods that contain natural sugar, like fruits and vegetables. Unlike added sugar, natural sugar hasn�t been stripped of the vitamins, minerals, and fiber Mother Nature packaged them in.
But if you can dial your intake of added sugar way back, you�ll start to rack up some amazing body benefits, like these.
Your skin will look younger
Think less sag and fewer wrinkles. Studies suggest that the amount of sugar in the blood (which is affected by how much sugar you eat) sets up a molecular domino effect called glycation, which ultimately leaves skin less firm and elastic. Already bothered by premature lines? Cutting your sugar intake can reduce visible signs of aging, research shows.
You�ll have less belly fat
This is the visceral or �deep� fat that builds up around vital organs like your liver, pancreas, and intestines. Stubborn and hard to get rid of, it�s also dangerous; visceral fat is a known risk factor for heart disease and diabetes. In 2016, data from more than 1,000 people who are part of the ongoing Framingham Heart Study showed that the more sugar-sweetened beverages they consumed, the higher their level of visceral fat.
Added sugars are simple carbohydrates. This means they�re digested fast and enter your bloodstream quickly, providing that sugar high that helps jump-start your energy and alertness. But as anyone who relies on a candy bar or pastry for a pick-me-up knows, once that shot of sugar is metabolized, you’re in for a crash.
When you need fuel, swap the sugar-sweetened meals and snacks for items that are low in sugar yet high in protein and/or fat, like almonds. Because they take longer to digest, they�ll supply you with a steadier stream of energy that will last longer, says Diane Sanfilippo, a certified nutrition consultant and author of The 21-Day Sugar Detox.
You�ll lower your risk of obesity
Epidemiological studies show a striking correlation between weight gain and sugar consumption. One study that looked at data from 75 different countries between 1997 and 2010 found that a 1 percent rise in soft drink consumption across a nation was linked to an additional 4.8 people out of 100 being overweight and an additional 2.3 people out of 100 being obese.
Here are some more numbers: sugar has 16 calories per teaspoon, which may not sound like a big deal. But considering how much added sugar is loaded into tons of products, consuming sweetened foods can easily add hundreds of calories to your diet�calories that you may not need and may end up as dangerous fat around your middle.
A healthy heart helps you power through your day, from that a.m. spin class to a late deadline at work. But the more added sugar in your diet, the higher your risk of dying of heart disease, even if your weight is in a healthy range.
In one 2014 JAMA study, researchers found that those who consumed the highest amount of sugar � accounting for more than 21 percent of their totally daily calories �had double the heart disease death risk of people who took in 17 to 21 percent of their daily calories from the sweet stuff. This group in turn had a 38 percent higher risk of dying from cardiovascular disease compared to those who kept their sugar intake to 8 percent of their daily calories (The FDA says getting 10% of your daily calories from added sugar is a solid guideline).
Researchers have long debated whether there was a direct connection between eating sugar and developing type 2 diabetes. But recent research has lent support to this theory. A 2014 Stanford University study of 175 countries found that the more sugar that is available in a population’s food supply, the higher the diabetes rate�and this was true even when a country’s obesity rate was not factored in. (Obesity itself can set a person up for diabetes).
Epidemiological data also suggests that among other factors, diets high in sugar�even in diets that are not necessarily high in calories�cause the body to store visceral fat around the middle, and that can lead to insulin resistance and a diabetes diagnosis.
Scientists believe that turmeric my hold the key to better bone density
The study involved fit, healthy and slim men and women who all suffered declining bone density.
In just six months, those taking a daily tablet of the turmeric and soy lecithin formulation boosted bone density by seven per cent compared with a group given a placebo.
The quality of bone in the heels, jaws and fingers of the group – who had an average age of 70 – was measured at the start of the project using specialized ultrasound scanning.
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By the end of the trial bone density had increased in all three sites by up to 7 per cent above the placebo, suggesting a significant benefit.
Curcumin researchers from the University of Sydney, Australia, along with INSERM the French government’s medical research laboratories, and a team of doctors from four prestigious American universities, have published similar conclusions.
Doctors are increasingly concerned that almost three quarters of elderly people lose strength-providing bone mineral.
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The spice may hold the secret to battling osteoporosis in the elderly
The condition called osteopenia, mostly caused by a lack of exercise, can worsen into osteoporosis and lead to fatal fractures if untreated.
We’re are delighted by these results
Alf Lindberg
Every year about 65,000 people suffer hip fractures caused by bone fragility, leading to the deaths of up to 35 per cent of victims in the older age groups.
Turmeric+, which comes from the powerful root of the curcumin plant, is sold in Britain by the Cambridge bioscience company Cambridge Nutraceuticals under the brand FutureYou.
Alf Lindberg, a former Nobel prize committee member who is a scientific spokesman for Cambridge Nutraceuticals, said: �We’re are delighted by these results, and we are stepping up our osteoporosis research programme with turmeric as a result.
�Our formulation is better absorbed by the human body than turmeric in its natural form, and we believe it could offer an earlier side-effect free alternative for people at risk from osteoporosis.�
Bone mineral density is regulated by maintaining a balance between bone-building osteoblast cells and osteoclasts, which are designed to mop up ageing bone cells for replacement.
In older people osteoclast activity may outweigh the rate of bone replacement.
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Almost three quarters of elderly people lose strength-providing bone mineral
Stefano Togni, is scientific spokesman for the world’s largest researcher into plant based treatments, Indena, which developed the raw material for Turmeric+.
He said the Italian company had produced similar promising bone-building results with the uniquely bioavailable compound in animal studies.
He said: �Our work suggests this form of curcumin dampens down the rate of bone resorption which could be very good news, because it would mean that people who are in the early stages of bone loss will now have a treatment.”
Elise Verron, a specialist in the evaluation of medicines for INSERM from the University of Nantes in France, was a co-author of a review of the bone-building properties of curcumin and turmeric in the Nature journal Bonekey.
Tue, April 25, 2017
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She agrees that the key to harnessing its power will depend on developing strategies to improve absorption.
She said: �In the past decade there has been growing interest in curcumin because of its low toxicity and multiple therapeutic actions including anti-cancer, anti-inflammatory and anti-microbial activities, but few studies have looked at its effect on bone tissue.
�At the moment it is too early to get a clear idea of the benefit.�
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Turmeric comes from the powerful root of the curcumin plant
Luca Giacomelli, of the department of integrated diagnostics at Genoa University, who was one of the leaders of the new Italian study, said the results were promising.
But he cautioned that the effect cannot be replicated simply by adding regular curry to the diet because turmeric in food is less easily absorbed.
He said: �People need to take this kind of high quality supplement under medical supervision.�
The findings may also come as good news for thousands of people advised by doctors to take bisphosphonate drugs designed to maintain bone density by reducing the rate of bone breakdown.
Latest research has suggested that long term users of these drugs may suffer ‘microcracks’.
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