Back Clinic Supplements. What is more fundamental to our existence than diet and nutrition? Most of us eat at least three times a day. This creates a cumulative effect, as either our diet help fuel our body or it harms it. Bad nutrition, diet, and obesity can lead to osteoarthritis, osteoporosis, and chronic pain. Knowing dietary supplements such as vitamins and proper nutritional balance, and effective techniques to shed weight can help those striving to change their new healthy lives.
A dietary supplement is used to provide nutrients to increase their consumption or provide non-nutrient chemicals claimed to have biological/beneficial effects. Dietary supplements come in all shapes and sizes. There are capsules, drinks, energy bars, powders, and traditional tablets. The most popular are calcium, iron, vitamins D and E, herbs like echinacea and garlic, and specialty products like glucosamine, probiotics, and fish oils.
If you are experiencing any of these situations, then it might be something that may be attacking your immune system. Why not try to add some beta-glucan into your diet and overall health.
Throughout the last several years, beta-glucans have been gaining much attention due to the emergence of medicinal mushrooms in Western cultures. Across the country, studies have found that beta-glucans have been ubiquitous in the health food stores due to their immunomodulatory properties and cancer-protective effects. Since edible fungi have been known as the main source for beta-glucans, surprisingly though beta-glucan can be presented in a variety of foods like oats, barley, seaweeds, and yeast. Beta-glucan can also be found in dietary supplements for the body to consume.
Beta-glucans
Beta-glucan is technically a non-starch polysaccharide, a prebiotic fiber that is formed by ?-1,3 and 1,6 glycosidic bonds. With beta-glucan, it can possess numerous health benefits depending on the molecular structure of each type of bond. Studies have shown that beta-glucans that are found in cereal grains can help lower cholesterol levels and can effectively bind serum cholesterol. Beta-glucans can even play a beneficial role in obesity, metabolic disorders, and other chronic non-communicable diseases. Since beta-glucans are a prebiotic fiber, research shows that they can play a significant role in promoting a healthy microbiome in the body. It means that beta-glucan can stimulate the growth of beneficial bacteria species, mitigating pathogenic ones, and even modulating inflammation to optimize the gut environment in the body.
Beta-glucans for Immune Support
In a 2019 study, it stated that �the relationship between immunity and nutrition is considered to be completely interconnected.� More studies have shown that beta-glucan can act on several immune receptors that can stimulate immune cell activity. This includes T-cells, macrophages, neutrophils, monocytes, natural killer (NK) cells, and dendritic cells. One of the studies showed how beta-glucans could pose modulatory effects on both the innate and adaptable branches of the immune system. One of the protein receptors is known as dectin-1; this protein receptor is on the surface of macrophages and dendritic cells.
What dectin-1 can do is that they can initiate and regulate the innate immune response by insoluble binding ?-1,3, and 1,6 glucans, plus it has become essential for controlling infections in the body. While water-soluble ?-glucan can bind to the CR3 receptors, thus triggering the adaptive immune response to the body. With ?-glucans, they can enhance phagocytosis while also triggering the release of various interleukins and cytokines, thus possessing cytotoxic anti-cancer properties. Studies have shown that TNF-?, IFN-?, and NF-??, can help to support the regulation of the T-helper cell 1 and Th-2 balance for immunological homeostasis for the body. Surprisingly in other articles, they talked about how yeast-derived ?-1,3/1,6 glucan can be delivered as an oral supplement for the winter months. The article study showed how it demonstrates its protective effects against upper respiratory tract infections in the body. The study even showed how it could reduce the upper respiratory tract infection symptoms that are already in older adults that have been infected. Another study showed that ?-glucan have cytoprotective abilities from viral infections and provide immunomodulatory properties to the body and the immune system.
With the population of many individuals, it turns out that the elderly population can benefit from the ?-glucan compound. With this compound, everyone can have a healthy immune system, especially during the cold and flu season. Having a healthy immune system is important because that way, the body can protect itself from harmful pathogens through functional medicine, healthy nutritious food, and supplements. By using these options, the body can heal itself and can dampen the effects of cold and flu symptoms.
More Research on Beta-glucan
Research studies have shown that ?-1,3 glucan from the fungal cell wall is one of the key ingredients for vaccines. The research shows as well that ?-glucan can produce robust humoral and cellular immune responses for the body when it is exposed to antigens. What is interesting is that ?-glucan is known to exert antioxidant activities in the body. With their reactive oxygen species (ROS) scavenging abilities, they can exert the antioxidants into the circulatory system and the mucosal immune system. There is a study that shows that ?-glucan in barley can possess a higher total of antioxidants significantly at a better capacity than oats and yeast. The study showed that ?-glucan could be subdivided into two groups depending on whether specific receptors are involved or not. It also stated that ?-glucan could be validated as a functional food ingredient.
Conclusion
All in all, ?-glucan is an amazing non-starch polysaccharide prebiotic fiber that has amazing properties that can help the body. ?-glucan can be found in mushrooms and a variety of other foods like seaweed and oats. This compound can help boost up the body’s immune system and can dampen any harmful pathogens effects that the body has come in contact with. This compound�s beneficial properties are amazing for anyone that consumes it and even added it to their daily diet. Some products combined with ?-glucan can support the immune system with hypoallergenic nutrients and targets amino acids.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
References:
Bacha, Umar, et al. �Nutraceutical, Anti-Inflammatory, and Immune Modulatory Effects of ?-Glucan Isolated from Yeast.� BioMed Research International, Hindawi, 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5587958/.
Chan, Godfrey Chi-Fung, et al. �The Effects of Beta-Glucan on Human Immune and Cancer Cells.� Journal of Hematology & Oncology, BioMed Central, 10 June 2009, www.ncbi.nlm.nih.gov/pmc/articles/PMC2704234/.
Fuller, Richard, et al. �Yeast-Derived ?-1,3/1,6 Glucan, Upper Respiratory Tract Infection and Innate Immunity in Older Adults.� Nutrition, Elsevier, 23 Mar. 2017, www.sciencedirect.com/science/article/abs/pii/S0899900717300539.
Jurgelewicz, Michael. �New Study Demonstrates Novel Yeast-Derived Beta-Glucan Provides Immunomodulatory Effects in Older Adults.� Designs for Health, 21 Oct. 2018, blog.designsforhealth.com/si-42214/new-study-demonstrates-zinc-supplementation-improves-clinical-outcomes-from-traumatic-brain-injury.
Levitz, Stuart M, et al. �Exploiting Fungal Cell Wall Components in Vaccines.� Seminars in Immunopathology, U.S. National Library of Medicine, Mar. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4329074/.
Nakashima, Ayaka, et al. �?-Glucan in Foods and Its Physiological Functions.� Euglena, Co., Ltd., 14 Aug. 2017.
Nakashima, Ayaka, et al. �?-Glucan in Foods and Its Physiological Functions.� Journal of Nutritional Science and Vitaminology, U.S. National Library of Medicine, 2018, www.ncbi.nlm.nih.gov/pubmed/29491277.
Team, DFH. �Modulators of Immune Health: Beta-Glucans.� Designs for Health, 26 Mar. 2020, blog.designsforhealth.com/node/1219.
Team, DFH. �Mushrooms for Nutritional Medicine.� Designs for Health, 14 Feb. 2019, blog.designsforhealth.com/node/952.
Vetvicka, Vaclav, et al. �Beta Glucan: Supplement or Drug? From Laboratory to Clinical Trials.� Molecules (Basel, Switzerland), MDPI, 30 Mar. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6479769/.
The University offers a wide variety of medical professions for functional and integrative medicine. Their goal is to inform individuals who want to make a difference in the functional medical fields with knowledgeable information that they can provide.
Smart supplementation along with proper nutrition is one of the biggest factors and plays a large role in an individual’s health. You are what you eat is true. Feeding the body with vital vitamins and minerals promotes growth and healing. Filling up on processed, fatty foods does the opposite. The bones in the spine and throughout the body need nutrients to continue to rebuild and maintain strength throughout life.
A balanced diet rich in:
�Calcium
Vitamin D
Magnesium
This is the best way to nourish the body’s bones and ward off spinal problems, like spinal fractures, and osteoporosis. Inadequate diets or medical issues can create nutritional gaps. This is where vitamins or mineral supplements come in. Supplements are not a cure-all, but they can create a safetyhealth net when taken properly.
Supplement Smart
These supplements for bone health, fill in nutritional gaps. They are not necessary if the key nutrients the body needs from a proper diet are already there. However, individuals use supplements as a replacement for certain foods, this is not how they should be used. Actual food supplies multiple nutrients, along with minerals, and vitamins that are beneficial for health and are not found in supplements.
Taking a Supplement to Strengthen the Spine
The body’s dietary needs change throughout life, so adding supplements as you age or during pregnancy can help maintain health. Calcium and vitamin D requirements vary based on age and sex.When it comes to protecting spine bone health, certain individuals may need supplements to ensure their bodies are processing calcium and vitamin D properly.
This includes:
Individuals who had intestinal bypass procedure
Those with food absorption conditions, like Celiac or Crohn�s disease
People who eat few or no dairy products, like vegans or those that are lactose intolerant
Is a calcium supplement right for you?
The only way to definitively know is by having a conversation with your doctor. Then you can supplement smart.
Supplement Safety
Because nutritional supplements can be purchased over the counter, individuals assume�incorrectly�that they are completely safe. Dietary supplements can interfere with absorption, other supplements, medications, and can be toxic if taken in high doses.
For example:
Calcium and iron supplements can prevent each other from being fully absorbed when taken together. This is true of many minerals, including magnesium, because they get into�absorption�competition with each other and so are best taken separately.
Supplements taken together can cause too much of either one to be absorbed. This is the case with high-dose vitamin D supplements, which can cause too much calcium absorption.
Too much calcium can increase raise the risk of having a heart attack or stroke. Taking more than 1,000-1,200 mg of calcium per day is pointless because the body cannot process that much calcium at once.
Are your supplements helping or hurting you? The best way to know is to talk to your doctor whenever you change medication or a supplement program, even when just adding a new vitamin to the mix. An underused resource for supplement advice is a pharmacist. They will know whether the mix of supplements and medicines being taken pose any risk of negative interaction. And a pharmacist can help recommend a trustworthy product.
Supplement Success
Here are a few tips to get the most benefits if you and your doctor think a calcium supplement can help support spinal bone health.
Buy supplements with the USP symbol. This indicates that the supplement has been independently evaluated and certified.
Take your supplement as directed, ideally with a meal.
Take doses no higher than 500-600 mg, no more than 2-3 times a day, for a maximum of 1,000-1,200 mg.
Drink plenty of water as some supplements can cause constipation.
Do not take calcium supplements with a high-fiber meal or laxative. This can interfere with calcium absorption.
Supplements Support Spine Health
Remember that supplements are exactly that supplements. Eating foods rich in calcium, vitamin D, and magnesium is the best way to build/maintain strong healthy spinal bones and prevent debilitating health problems. If you are concerned about your diet, talk with your doctor or a health coach about a smart supplementation regimen to meet your nutritional needs.
Digestive problems subside with rest and relaxation?
Crave sweets during the day?
Eating sweets does not relieve the craving for sugar?
Stomach pains, burning, or aching 1-4 hours?
If you are experiencing any of these situations, then something is disrupting your gut system. Why not try some aloe vera to dampen the symptoms.
Aloe Vera
Whenever someone thinks of aloe vera or aloe itself, the mind goes to sunburns and inflamed redden skin in general. Aloe vera has claimed its way to fame by soothing sunburnt skin; however, this long-celebrated medicinal plant has many properties and potential applications that go way beyond soothing inflamed skin.
Throughout the recent years, there was a surge in research about the gut microbiome and how it both affects and is affected by various diseases. The various research showed that SCFAs (short-chain fatty acids) producing a byproduct of colonic bacteria and fermenting dietary fibers, thus having critical signaling functions and playing a role in the gut-associated immune response. Studies have shown that butyric acid or butyrate may be beneficial for brain health in the body. Furthermore, the study also mentioned how SCFAs could contribute to reducing the inflammation in the gut while also associating between high-fiber diets and reducing the risk of colon cancer.
Aloe Vera�s Prebiotic Effects
Other studies showed that aloe vera has impressive prebiotic effects when it is being incubated within the human gut bacteria cultures. When a culture of mixed bacteria is being incubated with aloe vera, it shows a linear increase in butyric acid and an increase production of acetic acid when Bifidobacterium infantis is incubated with aloe vera. Studies show that when people have an increased intake of their dietary fibers, it can bring negative consequences to their bodies. The research talks about how having an increase in fiber is an obvious way to help support SCFAs, but for people who want to increase their fiber intake, they should consume aloe vera.
Aloe’s prebiotic effects are fantastic due to the chemical structure of some of its components. Surprisingly the aloe vera gel is about 55% polysaccharides and contains a compound called acemannan. With acemannan and the other polysaccharides in the aloe plant, many researchers have believed that these components are a significant contributor to aloe’s prebiotic and gut supportive effects. Since acemannan contains sugar molecules that are being linked to glycosidic bonds, they cannot be digested by human enzymes. However, with the body�s intestinal bacteria, studies have found that it can cleave the bond that acemannan has created and making acemannan digestible for the colonic flora. Another compound that aloe has is known as barbaloin. This compound contains other bonds that are inaccessible to the human digestive enzymes but is cleavable by the GI flora in the body.
Aloe Helping with Insulin
Aloe supplements can provide beneficial properties to battle against diabetes. A study from India stated that individuals who tale aloe vera gel powder for three months showed a substantial improvement in their glycemic control and cardiometabolic health.
Earlier studies have found out that aloe supplementation can improve the biomarkers of cardiometabolic health in the body as well. The study found that individuals who are pre-diabetic or have metabolic syndrome were given the standardized aloe extract for about eight weeks, and the results were astounding. The results showed that the consumed aloe supplement leads to a significant reduction in total cholesterol and LDL-C in the body as well as fasting glucose and fructosamine. Consuming aloe can cause a reduction in insulin in the body so people can start feeling better.
There is a more recent study that confirmed that aloe supplementation helps improve glycemic control and lipid profiles for pre-diabetic individuals. The results showed a decrease in triglycerides, total cholesterol, and LDL-C, as well as an increase in HDL in the body. Research found out that low-carbohydrate and the ketogenic diets are highly effective for improving blood glucose and insulin, especially for anyone who has type 2 diabetes. By adding aloe supplementation, it can be a powerful adjunct, especially for those who have a difficult time sticking to a strict low-carb regimen when a person’s dietary change is absent.
Conclusion
Aloe vera is an exotic plant that has many beneficial properties that can not only reduce red, inflamed skin but can provide support to the gut system and help individuals who may be pre-diabetic. Aloe vera can help the body’s gut system by making sure that no disruption and inflammation can affect the intestinal barrier, causing leaky gut. By consuming aloe vera in plant form or even using it as a supplement can provide fantastic health benefits for the body. Some products can be taken with aloe vera in order to make sure the gastrointestinal is being healthy by supporting the metabolic system and the gastrointestinal. These products offer hypoallergenic nutrients, enzymatic cofactors, and phytonutrients for overall health and wellness.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
References:
Quezada, Maria Paz, et al. �Acemannan and Fructans from Aloe Vera (Aloe Barbadensis Miller) Plants as Novel Prebiotics.� Journal of Agricultural and Food Chemistry, 26 Oct. 2017, pubs.acs.org/doi/10.1021/acs.jafc.7b04100.
Alinejad-Mofrad, Samaneh, et al. �Improvement of Glucose and Lipid Profile Status with Aloe Vera in Pre-Diabetic Subjects: a Randomized Controlled-Trial.� Journal of Diabetes and Metabolic Disorders, BioMed Central, 9 Apr. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4399423/.
Bourassa, Megan W, et al. �Butyrate, Neuroepigenetics, and the Gut Microbiome: Can a High Fiber Diet Improve Brain Health?” Neuroscience Letters, U.S. National Library of Medicine, 20 June 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4903954/.
Choudhary, Monika, et al. �Hypoglycemic and Hypolipidemic Effect of Aloe Vera L. in Non-Insulin Dependent Diabetics.� Journal of Food Science and Technology, Springer India, Jan. 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC3857397/.
Devaraj, Sridevi, et al. “Effects of Aloe vera supplementation in subjects with prediabetes/metabolic syndrome.” Metabolic syndrome and related disorders�vol. 11,1 (2013): 35-40. doi:10.1089/met.2012.0066
Jurgelewicz, Michael. �Diversity Is the Key to a Healthy Gut.� Designs for Health, 5 Apr. 2018, blog.designsforhealth.com/diversity-is-the-key-to-a-healthy-gut.
Pogribna, M., et al. �Effect of Aloe Vera Whole Leaf Extract on Short Chain Fatty Acids Production by Bacteroides Fragilis, Bifidobacterium Infantis, and Eubacterium Limosum.� Society for Applied Microbiology, John Wiley & Sons, Ltd, 19 Mar. 2008, sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472-765X.2008.02346.x.
Sivaprakasam, Sathish, et al. �Benefits of Short-Chain Fatty Acids and Their Receptors in Inflammation and Carcinogenesis.� Pharmacology & Therapeutics, U.S. National Library of Medicine, Aug. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4942363/.
Team, DFH. �Alternative Applications for Aloe.� Designs for Health, 5 Mar. 2020, blog.designsforhealth.com/node/1209.
The University offers a wide variety of medical professions for functional and integrative medicine. Their goal is to inform individuals who want to make a difference in the functional medical fields with knowledgeable information that they can provide.
If you are experiencing any of these situations, then you might want to try astaxanthin.
The body needs specific vitamins, minerals, and supplements from food, in order to function correctly. The variety of these nutrients can be found in healthy foods like fruits, vegetables, lean meats, and whole grains are precisely what the body needs. One of the essential nutrients that the body needs is antioxidants. Antioxidants help the body get rid of free radicals that can cause the body to become overly stressed and leading it to develop chronic illnesses. There is an antioxidant that can help the body and can be found in berries and pomegranates, and it is called astaxanthin.
Astaxanthin
Astaxanthin is a xanthophyll carotenoid that can be found in various microorganisms and marine animals. Astaxanthin is common for humans to apply and consume into the body while also being different. This red, fat-soluble pigment is quite different from the other kinds of food that contain carotenoids. Astaxanthin surprising does not contain vitamin A like all the other food containing carotenoids, and astaxanthin is an impressive antioxidant. Studies have shown that astaxanthin can not only be beneficial for the eyes but can provide nutritional support as well as having potential health-promoting effects in preventing and treating various diseases that can harm the body. Some of the various diseases that can harm the body when there is an excessive amount of free radicals can include:
Various cancers
Chronic inflammatory diseases
Metabolic syndrome
Diabetes
Gastrointestinal diseases
Another study found that astaxanthin was superior to fish oil due to astaxanthin having the ability to enhance the body’s immune response and thus lowering the risk of vascular and infectious diseases that can harm the body, causing it to dysfunction.
A Powerful Antioxidant
There are some fantastic beneficial properties that astaxanthin can provide for the body and help improve the body�s systems as well.
Astaxanthin is a powerful antioxidant since various chronic diseases are rooted in a disproportionate balance of reactive oxygen and nitrogen species to antioxidants. Studies have shown�that astaxanthin has been known to scavenge free radicals more effectively out of the body than beta-carotene. There was another study showing how the body�s DNA was damage due to low plasma 8 -OHdG (8-hydroxy-2′-deoxyguanosine) levels.
Boosts the Immune System
The publication of the immunomodulatory effects of astaxanthin is not getting enough attention as they should be. A test study has reported that dietary astaxanthin was able to stimulate mitogen-induced lymphocyte proliferation. This will help increase the natural killer cell cytotoxicity and even delay the hypersensitivity response in the body while also increasing the numbers of total T and B cells in the peripheral blood in the body. Another study showed how astaxanthin could help significantly enhanced lymphocyte proliferation in vitro and ex vivo. The studies also found that astaxanthin can be consumed in high concentrations without the risk of cytotoxicity.
Controls Glucose and Lipids
Surprisingly there has been new research that has been revealing about another unique but vital role that astaxanthin has. The studies show that it can modulate peroxisome proliferator-activated receptors or PPARs. What this function does is that it may have various applications in human health, including producing glucose and lipid homeostasis. Since PPARs are members of the nuclear hormone receptors in the body, they are a superfamily that plays roles in the expression of many genes that are regulating cellular differentiation and many other functions in the body.
There are at least three subtypes of PPARs that helps the major organs and help the metabolism of glucose and lipids. PPAR? can primarily be expressed in the liver, kidney, heart, and skeletal muscle, where it can be involved in lipid metabolism and insulin sensitivity to the body. Another subtype of PPARs is PPAR?, which plays a role in glucose and lipid homeostasis but also is the site of action in the adipose tissue in the body. When astaxanthin is being involved, astaxanthin is a PPAR? agonist but can act as either an agonist or antagonist to PPAR? receptors. Studies have found that PPAR? agonist and PPAR? antagonist in astaxanthin can decrease cholesterol and triglycerides in loaded HepG2 cells, while changing several enzymes expressions that are being involved in lipid and glucose metabolism pathways, thus resulting in a hypolipidemic effect in the body.
Exercise Enhancement
Surprisingly astaxanthin can be used to prevent exercise-induced free radical production and is a lesser-known application. Astaxanthin can enhance exercise performance and even improve the recovery process. The increase in the reactive oxygen and nitrogen species or RONS are being produced during an exercise regime is deleterious to the health. It is often combated with a matching increase in the endogenous antioxidant enzymes. However, when a person is doing excessive exercises, it can cause RONS to rise above the body’s natural capacity to eliminate them. This will cause an increased risk of oxidative damage in lipids, protein, and DNA molecules. In a review study, it showed the ability of astaxanthin to squelch the RONS generating during exercising. It reported that the antioxidant effects of astaxanthin could provide a variety of benefits to athletes.
Conclusion
Astaxanthin is a powerful immunomodulatory antioxidant that can support numerous biological pathways that are in the body. It can dampen the effects of a variety of chronic diseases and illnesses that can harm the body. Astaxanthin is useful for being a therapeutic and powerful nutraceutical while also being an excellent addition for someone who needs supplements to support their general health and well-being. Some of the products here are beneficial to the body as they help support the immune system while providing more excellent stability.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
References:
Ambati, Ranga Rao, et al. �Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications–a Review.� Marine Drugs, MDPI, 7 Jan. 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC3917265/.
Brown, Daniel R, et al. �Astaxanthin in Exercise Metabolism, Performance and Recovery: A Review.� Frontiers in Nutrition, Frontiers Media S.A., 18 Jan. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5778137/.
Brown, Daniel R, et al. �Astaxanthin in Exercise Metabolism, Performance and Recovery: A Review.� Frontiers in Nutrition, Frontiers Media S.A., 18 Jan. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5778137/.
Choi, Chang-Ik. �Astaxanthin as a Peroxisome Proliferator-Activated Receptor (PPAR) Modulator: Its Therapeutic Implications.� Marine Drugs, MDPI, 23 Apr. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6521084/.
Lin, Kuan-Hung, et al. �Astaxanthin, a Carotenoid, Stimulates Immune Responses by Enhancing IFN-? and IL-2 Secretion in Primary Cultured Lymphocytes in Vitro and Ex Vivo.� International Journal of Molecular Sciences, MDPI, 29 Dec. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4730289/.
Park, Jean Soon, et al. �Astaxanthin Decreased Oxidative Stress and Inflammation and Enhanced Immune Response in Humans.� Nutrition & Metabolism, BioMed Central, 5 Mar. 2010, www.ncbi.nlm.nih.gov/pmc/articles/PMC2845588/?report=reader.
Team, DFH. �Applications of the Antioxidant, Astaxanthin.� Designs for Health, 27 June 2019, blog.designsforhealth.com/node/1047.
Yuan, Jian-Ping, et al. �Potential Health-Promoting Effects of Astaxanthin: a High-Value Carotenoid Mostly from Microalgae.� Molecular Nutrition & Food Research, U.S. National Library of Medicine, Jan. 2011, www.ncbi.nlm.nih.gov/pubmed/21207519.
The University offers a wide variety of medical professions for functional and integrative medicine. Their goal is to inform individuals who want to make a difference in the functional medical fields with knowledgeable information that they can provide.
If you are experiencing any of these situations, then there might be some dysfunction in your body�s system, including the immune system. Why not try the Chinese herb, astragalus to help alleviate the symptoms.
Astragalus
In traditional Chinese medicine, the herb astragalus has been used for thousands of years and has been known to strengthen chi or qi life force in the body. This herb has been known to be typically employed in conditions that are related to general weakness in the body like fatigue, anemia, a poor appetite, cardiovascular diseases, and other conditions that can weaken the body. Surprisingly though, astragalus can be used to optimize kidney health and, with the combination of ginseng and echinacea, can boost up the body’s immune system. There is a variety of astragalus that are native to Northeast Asia, and its roots need to be dried and powdered to be transformed to be consumed as a capsule or as a tea.
Astragalus Beneficial Properties
Studies have found that astragalus�s beneficial pharmacological effects might contain phytochemical components, which include a host of saponins polysaccharides and flavonoids that the body’s immune system needs to function correctly. Another study found that astragalus contains about twenty trace minerals that are highly important for the body. With astragalus extract, it has immune-modulating properties in vivo and in vitro in both animals and humans, and research shows that the herb stimulates and influences on the immune response cytokines while also leaving the inflammatory cytokines unaffected.
Some of the beneficial properties that astragalus can have on the body are still being researched; however, this Chinese herb can help the body to function correctly and are effective.
Improving the Immune System
Studies have shown that astragalus contains some beneficial plant compounds that may enhance the body’s immune system. Studies show that the primary role for the immune system is that it helps protect the body from foreign pathogens like harmful bacteria and viruses that can cause a person to be ill. Research has found out that there is some evidence that astragalus can increase the body�s production of white blood cells, which will help prevent illnesses from entering the body. In other research studies, it has been found that astragalus root has been known to help the body kill bacteria and viruses caused by infections. Even though the research may be limited, there are still studies that show that astragalus can fight off viral infections like the common cold and liver infections in the human body.
Improving the Heart Function
Research shows that astragalus may be able to improve heart function by widening the blood vessels and increasing the amount of blood that is being pumped from the heart. In a clinical research study, it showed that patients were given at least 2.25 grams of astragalus for two weeks and have experienced a more significant improvement in their heart function. In another study, it shows that astragalus may help reduce the symptoms of myocarditis, which is an inflammatory condition in the heart.
Improving Kidney Function
Astragalus can help support kidney health in the body by improving the blood flow to the kidneys and measuring the protein in the urine. A study has shown that proteinuria is a condition where there is an abnormal amount of protein that is found in urine, and it can be a sign that the kidneys are not functioning normally or may be damaged. Surprisingly, there was another study that showed that astragalus could improve proteinuria symptoms in individuals that have kidney disease. Studies have even found that astragalus may also help prevent infections for anyone who has a reduce kidney function and reducing the risk of a kidney disorder known as nephrotic syndrome.
Conclusion
Astragalus is a unique herb that can help the body’s immune system to function correctly. Even though there is a limited amount of research on this herb, but the beneficial properties it provides in the body are truly amazing. Astragalus can be consumed by capsules or even be brewed as a tea, so that way, people can enjoy the beneficial properties and that their body is performing excellently in health and wellness. Some products offer support to the body’s immune system and help target the amino acids that are intended to support the intestines while offering more support to the metabolic system.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
References:
Block, Keith I, and Mark N Mead. �Immune System Effects of Echinacea, Ginseng, and Astragalus: a Review.� Integrative Cancer Therapies, U.S. National Library of Medicine, Sept. 2003, www.ncbi.nlm.nih.gov/pubmed/15035888.
Fu, Juan, et al. �Review of the Botanical Characteristics, Phytochemistry, and Pharmacology of Astragalus Membranaceus (Huangqi).� Phytotherapy Research: PTR, U.S. National Library of Medicine, Sept. 2014, www.ncbi.nlm.nih.gov/pubmed/25087616.
Gao, Xing-hua, et al. �Saponin Fraction from Astragalus Membranaceus Roots Protects Mice against Polymicrobial Sepsis Induced by Cecal Ligation and Puncture by Inhibiting Inflammation and Upregulating Protein C Pathway.� Journal of Natural Medicines, U.S. National Library of Medicine, Oct. 2009, www.ncbi.nlm.nih.gov/pubmed/19548065.
Meixner, Makayla. �Astragalus: An Ancient Root With Health Benefits.� Healthline, 31 Oct. 2018, www.healthline.com/nutrition/astragalus.
Nalbantsoy, Ay?e, et al. �Evaluation of the Immunomodulatory Properties in Mice and in Vitro Anti-Inflammatory Activity of Cycloartane Type Saponins from Astragalus Species.� Journal of Ethnopharmacology, U.S. National Library of Medicine, 31 Jan. 2012, www.ncbi.nlm.nih.gov/pubmed/22155389.
Peng, T Q, et al. �Effect and Mechanism of Astragalus Membranaceus on Coxsackie B3 Virus RNA in Mice.� Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine, U.S. National Library of Medicine, Nov. 1994, www.ncbi.nlm.nih.gov/pubmed/7703635.
Piao, Yuan-lin, and Xiao-chun Liang. �Astragalus Membranaceus Injection Combined with Conventional Treatment for Viral Myocarditis: a Systematic Review of Randomized Controlled Trials.� Chinese Journal of Integrative Medicine, U.S. National Library of Medicine, Oct. 2014, www.ncbi.nlm.nih.gov/pubmed/25098261.
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Wang, Deqing, et al. �Study of the Effects of Total Flavonoids of Astragalus on Atherosclerosis Formation and Potential Mechanisms.� Oxidative Medicine and Cellular Longevity, Hindawi Publishing Corporation, 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3306992/.
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The University offers a wide variety of medical professions for functional and integrative medicine. Their goal is to inform individuals who want to make a difference in the functional medical fields with knowledgeable information that they can provide.
If there is one thing we are learning more and more about, it is that everything can be related back to inflammation and what we put inside our bodies. Point blank. The food you consume affects your genetics and your inflammatory response in the body. Headaches, achy joints, and overall fatigue have been directly linked to inflammation.
Inflammation
Inflammation was once thought to just be something that occurs when the body has an infection or we hurt ourselves as the body’s natural response. That fact is still true to this day. However, we now know more. Now, we are able to recognize inflammation occurring inside our organs and down to the cellular level.
Just as you roll your ankle and it becomes inflamed, if you eat the wrong foods your gut becomes inflamed. This can then be traced back to leaky gut and in some cases, autoimmune diseases.
So what can we do about it? What is actually happening in our bodies?
The human body is an amazing machine that we are still finding more about each and every day. Let’s first take a look at where this inflammation is coming from. Inflammation can enter the gut barrier as a toxin, protein, pathogen, LPS, or alcohol.
If our body is continuously exposed to these triggers, it can result in our immune system becoming dysregulated. Now that our body has these triggers, things like allergies, asthma, autoimmunity, and poor immune tolerance and regulation become our bodies new regular.
Amplifying Loop
These triggers then signal something called cytokines. Cytokines are tiny and dance around inside of the cell. These cytokines increase NF-kB activity.
NF-kB is then used to transcribe DNA and express an inflammatory state!
Now, our bodies are promoting inflammation, all because we let the toxins in. What we put into our mouth and our bodies matter. The foods we eat have the ability to provide nutrients to our cells, rather than facilitating in this ongoing inflammatory response chain.
How Do I Regain Control?
Nrf2 is a key protein in the body that has the function of regulating the genome. This helps the body balance gene expressions and the regulation of our genes. Another thing Nrf2 does is upregulate genes that encode antioxidant enzymes and antiinflammatory genes.
Essentially, Nrf2 helps to fight off inflammation and reduce oxidative stress. Nrf2 activity is part of the detoxification system our bodies naturally have. It helps us to not get sick from every single bacteria we come into contact with. However, Nrf2 is a pathway, not a supplement. So now the question becomes, How do we active Nrf2?
From The Kitchen to The Genes
As mentioned earlier, everything can be traced back to the kitchen and what we put into our mouth to nourish our body. A great way to ensure you are feeding your body what it needs is to make a smoothie in the morning. Smoothies can contain so many nutrient-dense foods to aid in Nfr2 activation.
First, start off with flaxseed in the blender. Blend it up so the flax seeds get broken up and open. Next, add in blueberries, raspberries, strawberries, acai berry powder, broccoli sprouts, and almond milk!
By providing your body and your cells with the nourishment they need, they will flourish. In addition to a smoothie, there are supplements that can aid in Nrf2 activation as well. These supplements include curcumin, fish oil, wormwood, and CoQ10.
It’s clear that the “American Diet” has been causing problems for us. The world is so busy and fast-paced that we are not taking the time or giving our bodies the consideration to shop and make nutritious home-cooked meals. We need to increase our vegetables, fruits, fibers, whole grains and decrease the carbs. Everyone has some degree of inflammation in their body, and many of us do not even realize it! I challenge us to give up fast food for an entire month, cut the soda, increase the lemon water and eat at least one salad a day during this month. By increasing our vegetables and creating plates that are more colorful, our bodies will thank us! – Kenna Vaughn, Senior Health Coach�
References:
Gordon, Jacob. �Recipes for NRF2 – MyBioHack: Unlock Your Maximum Potential.� MyBioHack, MyBioHack | Unlock Your Maximum Potential, 7 Nov. 2017, mybiohack.com/blog/recipes-for-nrf2.
Gordon, Jacob. �Why NRF2 Activation Can Make You More Sick – MyBioHack: Unlock Your Maximum Potential.� MyBioHack, MyBioHack | Unlock Your Maximum Potential, 2 Feb. 2020, mybiohack.com/blog/nrf2-cirs-sensitivities.
Lawrence, T. �The Nuclear Factor NF-�B Pathway in Inflammation.� Cold Spring Harbor Perspectives in Biology, vol. 1, no. 6, 2009, doi:10.1101/cshperspect.a001651.
Ma, Qiang. �Role of Nrf2 in Oxidative Stress and Toxicity.� Annual Review of Pharmacology and Toxicology, vol. 53, no. 1, 2013, pp. 401�426., doi:10.1146/annurev-pharmtox-011112-140320.
The scope of our information is limited to chiropractic, musculoskeletal,and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at915-850-0900.
Today, there can be a lot of confusion when it comes to diet. The information received can be contradicting, confusing, and leave individuals feeling lost. This can often result in giving up on the diet and being left with joint pain, inflammation, discomfort, headaches and more.
The reason why there is more than one diet out there is because the research is always advancing. We have come to realize that everyone’s body reacts to different food sources and diets differently.
Genetic Code
As more and more research is being done, the more we are realizing how the genetic factor of individual cells directly correlate to a patient’s weight, diet, and changes as they age. For years, as one would get older and start gaining weight, we would attribute it to age. Although age is a factor, what we are finding now is that the genes are actually changing as we age and that is what creates this weight gain.
Sure enough, there are also genes that will tell us if you are susceptible to snacking. These genes can detect if you have a predisposition for heightened snacking or satiety. Satiety is the feeling of fullness after a meal. If you have reduced satiety, you tend to snack more because you do not feel as full after the meals you eat.
Getting your genes tested will allow the treatment plans created to be more personal and more geared to see results! Believe it or not, your genes can tell us if you are genetically prone to obesity,� if you have weight loss resistance when it comes to carbohydrates, and how your body responds to exercise! Using the genes, we can see how many hours per week you will need for weight loss or to maintain your current weight.
Proven Methods
The best option is to know your genes so the diet plan can be geared more towards you directly. However, if that is not a possibility right away, there has been one diet that has been proven time and time again to work for almost everyone. This diet is referred to as the Ketogenic Diet.
In simple terms, the ketogenic diet is a low carb, high-fat diet. This diet works by sending the body into a state of ketosis which burns fat as fuel.
Research shows that those using a ketogenic diet demonstrated a higher percentage of weight loss and kept the weight off longer when compared to those who did a low-fat diet.
Available Resources
Considering the fact that there is misinformation about diets out there, proper education is going to be the key. As someone who has gone through dietary changes myself and figuring out what works best with my body with type 1 diabetes for optimal health, the right team is what made me successful.
Surround yourself with those who are continuously educating themselves and have a system in place. For example, we make sure our patients get one on one time with the doctor and a health coach. From here, the health coach and patient become connected through a virtual database allowing the patient’s food, weight, supplements, hydration, BMI, BIA, and activity to be tracked by the health coach. The health coach can then instant message or video chat the patient throughout the week to ensure they are staying on track, staying motivated, and answer any questions they may have!
Do not be left confused over diets anymore! Remember that your genetic code holds the key to the right diet for you.
The right diet has the ability to make individuals see the results they have been waiting for. It all comes down to the genes. As mentioned, genes change over time but they hold the code. If you are someone who has struggled with diets, feeling good, or are stuck at a certain weight, I highly recommend getting tested! The information you gain from this is so beneficial! I have seen the results first hand, and they are eye-opening. They let you know if you have the genetics that will hold onto fat. This knowledge can help us prevent health issues such as metabolic syndrome! – Kenna Vaughn, Senior Health Coach�
Dr. Alex Jimenez�s Blog Post DisclaimerThe scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
REFERENCES
Bueno, Nassib Bezerra, et al. �Very-Low-Carbohydrate Ketogenic Diet v. Low-Fat Diet for Long-Term Weight Loss: a Meta-Analysis of Randomised Controlled Trials.� British Journal of Nutrition, vol. 110, no. 7, 2013, pp. 1178�1187., doi:10.1017/s0007114513000548.
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