Back Clinic Neuropathy Treatment Team. Peripheral neuropathy is a result of damage to peripheral nerves. This often causes weakness, numbness, and pain, usually in the hands and feet. It can also affect other areas of your body. The peripheral nervous system sends information from the brain and spinal cord (central nervous system) to the body. It can result from traumatic injuries, infections, metabolic problems, inherited causes, and exposure to toxins. One of the most common causes is diabetes mellitus.
People generally describe the pain as stabbing, burning, or tingling. Symptoms can improve, especially if caused by a treatable condition. Medications can reduce the pain of peripheral neuropathy. It can affect one nerve (mononeuropathy), two or more nerves in different areas (multiple mononeuropathies), or many nerves (polyneuropathy). Carpal tunnel syndrome is an example of mononeuropathy. Most people with peripheral neuropathy have polyneuropathy. Seek medical attention right away if there is unusual tingling, weakness, or pain in your hands or feet. Early diagnosis and treatment offer the best chance for controlling your symptoms and preventing further damage to the peripheral nerves. Testimonies http://bit.ly/elpasoneuropathy
The information herein is not intended to replace a one-on-one relationship with a qualified healthcare professional or licensed physician and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional. Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system. Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.
We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.
The blood-brain barrier is a protective shield that allows nutrients to enter the brain while keeping harmful components in the bloodstream from passing into the brain. However, many factors can cause a leaky blood-brain barrier. This can allow harmful components to penetrate the blood-brain brain, ultimately causing inflammation and brain health issues. A leaky blood-brain barrier is associated with many mental health issues and neurological diseases, including anxiety, depression, brain fog, fatigue, Alzheimer’s disease, Parkinson’s disease, attention deficit hyperactivity disorder (ADHD), and schizophrenia. In the article below, we will discuss natural ways which have been demonstrated to help fix a leaky blood-brain barrier and improve overall brain health.
Take Berberine
A variety of plants have an alkaloid known as berberine. This extracted substance has anti-inflammatory properties and it can ultimately promote brain health by protecting neurons. Scientists have also found that taking berberine can help lower “bad” cholesterol, improve gut health, and many others believe it may even have possible antidepressant properties. Other research studies have shown that it can reduce inflammation, improve blood-brain barrier permeability and decrease damage following a traumatic brain injury. However, further research studies are still required to demonstrate these effects.
Avoid Exposure to Mold
Mold and mycotoxins, or toxic metabolites released by mold, can cause severe brain health issues in people with certain sensitivities and intolerances. Exposure to these can also cause a leaky blood-brain barrier. In 2010, scientists demonstrated that exposure to mold and mycotoxins can increase BBB permeability by breaking down the blood-brain barrier. Moreover, low amounts of mold and mycotoxins can also be found in the foods we eat, including nuts, tea, coffee, and chocolate. Charcoal or bentonite clay supplements are powerful remedies that can capture toxins and release them out of the body.
Take B Vitamins
According to healthcare professionals, B vitamins have been found to help improve a leaky blood-brain barrier. B vitamin deficiencies can ultimately affect brain health. Taking vitamin B1 (thiamine) supplements can help fix BBB permeability. Research studies have also shown that vitamins B6, B9, and B12 can help improve brain health in older adults with increased homocysteine and moderate cognitive impairment. Homocysteine is an inflammatory component that can breakdown the blood-brain barrier. Fortunately, healthcare professionals have found that taking B vitamins can balance the blood-brain barrier.
Take Magnesium
Magnesium is a fundamental mineral that plays a vital role in a variety of structures and functions in the body, including enzyme, hormonal, and neurotransmitter activity. Magnesium is also one of the nutrients that people are most deficient in. This important mineral can increase growth hormones in the brain, support mitochondria, protect the brain from alcohol and help people overcome addiction and withdrawal. Research studies have also shown that taking magnesium can improve BBB permeability. Bananas, avocado, spinach, chard, almonds, pumpkin seeds, and dark chocolate have magnesium.
Take R-Lipoic Acid (RLA) and Acetyl-Carnitine (ALCAR)
R-Lipoic Acid (RLA) is a fat-soluble and stable, bioavailable form of lipoic acid or an antioxidant created by the body, that can pass through the blood-brain barrier and enter the brain. This essential antioxidant can also protect the brain from alcohol and support mitochondria. Research studies have found that RLA can decrease oxidative stress and inflammation as well as improve BBB permeability and. Acetyl-Carnitine (ALCAR) is an acetylated form of the amino acid carnitine that is synergistic with RLA. ALCAR is neuroprotective and it can help people improve brain fog as well as addiction and withdrawal.
Eat or Take Turmeric or Curcumin
Turmeric or curcumin, the spice that gives curry its yellowish color, is another fundamental ingredient for brain health that can help reduce stress and increase growth hormones in the brain. Turmeric or curcumin can also improve BBB permeability and promote overall brain health by maintaining and regulating the integrity of the blood-brain barrier. Research studies have also found that eating or taking turmeric or curcumin can help prevent damage to the blood-brain barrier due to glucose and oxygen deprivation by considerably decreasing oxidative stress and inflammation in the brain and body.
Take Vitamin D
Vitamin D is another fat-soluble vitamin that the skin produces when exposed to the sun. The brain, heart, muscles, and immune system, among other cells and tissues in the body, have vitamin D receptors. This fat-soluble vitamin is fundamental for a variety of structures and functions. Vitamin D deficiencies can also cause a variety of brain health issues and neurological diseases. Scientists have shown that vitamin D can decrease inflammation and improve BBB permeability. Vitamin D has also been demonstrated to help protect endothelial cells and improve BBB permeability in patients with multiple sclerosis.
Take Citicoline or Alpha GPC
Citicoline or CDP-Choline is another essential B vitamin and bioavailable form of choline. This substance can help improve brain fog. Research studies have also found that citicoline or CDP-Choline can prevent the breakdown of the blood-brain barrier following a stroke or traumatic brain injury and brain ischemia. Alpha GPC is another form of choline that has been shown to help support the blood-brain barrier. Scientists have also found that it can fix damage to the blood-brain barrier following a stroke or TBI, restoring cognitive function. You can also find some choline in egg yolks and beef liver.
Avoid Exposure to EMFs
According to a variety of research studies, radiofrequency electromagnetic fields or EMFs emitted from smartphones, laptops, and WiFi can affect the brain and mental health. Radiofrequency electromagnetic fields or EMFs can cause a leaky blood-brain barrier.��Several other research studies have found that radiofrequency electromagnetic fields or EMFs can increase BBB permeability. Increased blood-brain barrier permeability may ultimately result in the accumulation of brain cell and tissue damage as well as cognitive impairment. It’s important to be aware of the effects of being exposed to these devices.
Many factors can cause a leaky blood-brain barrier, ultimately causing increased BBB permeability, oxidative stress, inflammation and a variety of brain and mental health issues, including neurodegenerative diseases. The blood-brain barrier is a protective shield which allows nutrients to enter the brain while keeping harmful components in the bloodstream from passing into the brain. A leaky blood-brain barrier is associated with anxiety, depression, brain fog, fatigue, Alzheimer’s disease, Parkinson’s disease, attention deficit hyperactivity disorder (ADHD), and schizophrenia. Fortunately, several natural ways have been demonstrated to help improve overall brain health and wellness as well as help fix a leaky blood-brain barrier. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
The blood-brain barrier is a protective shield that allows nutrients to enter the brain while keeping harmful components in the bloodstream from passing into the brain. However, many factors can cause a leaky blood-brain barrier. This can allow harmful components to penetrate the blood-brain brain, ultimately causing inflammation and brain health issues. A leaky blood-brain barrier is associated with many mental health issues and neurological diseases, including anxiety, depression, brain fog, fatigue, Alzheimer’s disease, Parkinson’s disease, attention deficit hyperactivity disorder (ADHD), and schizophrenia. In the article above, we discussed more natural ways which have been demonstrated to help fix a leaky blood-brain barrier and improve overall brain health.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez
References:
The Star Academy. �How to Repair a Leaky Blood-Brain Barrier.� The Star Academy, The Star Academy, 16 Oct. 2018, thestaracademy.co.za/repair-leaky-blood-brain-barrier/.
Neurotransmitter Assessment Form
[wp-embedder-pack width=”100%” height=”1050px” download=”all” download-text=”” attachment_id=”52657″ /]
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue.
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance.
Neural Zoomer Plus for Neurological Disease
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention.
Food Sensitivity for the IgG & IgA Immune Response
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs.
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders.
Formulas for Methylation Support
XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download* All of the above XYMOGEN policies remain strictly in force.
The blood-brain barrier is a protective shield that allows nutrients to enter the brain while keeping harmful components in the bloodstream from passing into the brain. However, many factors can cause a leaky blood-brain barrier. This can allow harmful components to penetrate the blood-brain brain, ultimately causing inflammation and brain health issues. A leaky blood-brain barrier is associated with many mental health issues and neurological diseases, including anxiety, depression, brain fog, fatigue, Alzheimer’s disease, Parkinson’s disease, attention deficit hyperactivity disorder (ADHD), and schizophrenia. In the article below, we will discuss natural ways which have been demonstrated to help fix a leaky blood-brain barrier and improve overall brain health.
Improve Gut Health
Understanding the connection between the brain and the gut is important to treat a leaky blood-brain barrier. In 2014, scientists found that a group of mice that didn’t have bacteria in their gastrointestinal tract had very leaky blood-brain barriers. However, when the scientists of the research study introduced bacteria into the intestines of the unhealthy mice through a fecal transfer, their BBB permeability considerably improved. Increasing good bacteria in your gut can ultimately help improve a leaky blood-brain barrier. Eating probiotics, prebiotic fiber, and fermented foods can increase good bacteria in your GI tract.
Avoid Eating Gluten
According to many healthcare professionals, we should avoid eating gluten to promote brain health. In 2006, scientists found that gluten can cause a leaky blood-brain barrier because it increases zonulin, a protein that affects BBB permeability and results in neuroinflammation. Gluten sensitivity or intolerance can also cause visible changes in the white matter of the brain. Dr. David Perlmutter, MD, author of Grain Brain and Brain Maker states that gliadin, another protein found in gluten, can also affect BBB permeability. Moreover, other food sensitivities or intolerances can also cause a leaky blood-brain barrier.
Eat Food with Sulforaphane
Cruciferous vegetables, including Brussels sprouts, cabbage, and broccoli, among others, have sulforaphane, a phytochemical and well-known antioxidant with powerful anti-inflammatory properties, similar to turmeric or curcumin. Many research studies have shown that sulforaphane can help improve a leaky blood-brain barrier by decreasing BBB permeability, preventing the breakdown of the BBB, and improving cognitive functions after stroke and traumatic brain injuries. Sulforaphane in myrosinase-activated supplement form can also be taken. Myrosinase is an enzyme in broccoli that helps metabolize sulforaphane.
Eat Food with Resveratrol or Pterostilbene
Foods like raspberries, grapes, red wine, and dark chocolate have resveratrol, another powerful antioxidant with potent anti-inflammatory properties that can help prevent the development of neurodegenerative diseases caused by a leaky blood-brain barrier. Scientists have found that eating food with resveratrol can ultimately help promote growth hormones in the brain and support mitochondria function. According to research studies, resveratrol can also protect the blood-brain barrier. Numerous other research studies have also found that eating foods with resveratrol can have other health benefits, including:
Decreasing a leaky blood-brain barrier
Protecting the blood-brain barrier
Improving blood-brain barrier permeability
Research studies have also shown that resveratrol can help protect the blood-brain barrier against oxidized LDL-induced damage. Furthermore, scientists believe that eating food with resveratrol may be a safe and effective way to naturally reduce the severity of multiple sclerosis.�Foods like blueberries have pterostilbene, a substance similar to resveratrol, that can also help protect the blood-brain barrier by decreasing oxidative stress and inflammation. Many healthcare professionals also refer to pterostilbene as the “better resveratrol” because it is often believed to be best absorbed by the body than resveratrol.
Drink More Coffee
Caffeine can help promote overall brain health and support the blood-brain barrier. Research studies have shown that drinking coffee can help prevent the development of dementia, Alzheimer’s disease, and Parkinson’s disease, among other health issues, by protecting the BBB. Scientists have also found that caffeine blocks blood-brain barrier permeability. Other research studies have also shown that drinking coffee can help prevent neurodegeneration by balancing the BBB. Because drinking coffee and caffeine can commonly affect sleep, however, make sure to consume these early in the morning.
Take Omega-3 Fatty Acids
Omega-3 fatty acids are essential fats that are primarily found in fish. Although the body can’t produce these by itself, they are necessary for overall brain health. Omega-3 fatty acids can also help increase the growth hormones in the brain, help support mitochondria function, or help people overcome addiction and withdrawal, as well as help protect the blood-brain barrier. Scientists have found that taking omega-3 fatty acids can decrease damage to the BBB following a stroke or TBI and improve BBB permeability in people with multiple sclerosis. Omega-3 fatty acids can also be taken in supplement form.
Take Melatonin and Improve Sleep
Sleep is fundamental for brain health. Poor sleep has also been shown to increase blood-brain barrier permeability. Taking melatonin supplements can also help improve sleep.�Melatonin is a hormone that is released by a small gland in the brain, known as the pineal gland. Melatonin helps regulate the circadian rhythm, or sleep and wake cycles. Enough melatonin is necessary to fall asleep quickly and sleep deeply throughout the night. Research studies have also shown that taking melatonin can help balance the blood-brain barrier and prevent further damage following a stroke and/or traumatic brain injury.
Manage and Reduce Stress
According to research studies, stress can ultimately damage the blood-brain barrier. Chronic stress has also been found to increase inflammation and BBB permeability. Fortunately, managing and reducing stress can help fix the blood-brain barrier. Massage, acupuncture, eye movement desensitization and reprocessing (EMDR), emotional freedom techniques (EFT), heart-rate variability (HRV) training, and mindfulness meditation can also help manage and reduce stress. Taking supplements to help improve stress can also include, zinc, magnesium, ashwagandha, and phosphatidylserine, among others.
Avoid Drinking Alcohol
According to healthcare professionals, drinking too much alcohol can cause a leaky blood-brain barrier. Research studies have shown that acetaldehyde, a byproduct of alcohol metabolism, can increase oxidative stress and affect the blood-brain barrier, resulting in inflammation and a variety of neurological diseases and brain health issues. Although some types of alcohol are better than others, it’s best to considerably decrease or avoid drinking alcohol. If you suspect that you may have a leaky blood-brain barrier, make sure to talk to your doctor about how drinking too much alcohol may cause a leaky BBB.
Many factors can cause a leaky blood-brain barrier, ultimately causing increased BBB permeability, oxidative stress, inflammation and a variety of brain and mental health issues, including neurodegenerative diseases. The blood-brain barrier is a protective shield which allows nutrients to enter the brain while keeping harmful components in the bloodstream from passing into the brain. A leaky blood-brain barrier is associated with anxiety, depression, brain fog, fatigue, Alzheimer’s disease, Parkinson’s disease, attention deficit hyperactivity disorder (ADHD), and schizophrenia. Fortunately, several natural ways have been demonstrated to help improve overall brain health and wellness as well as help fix a leaky blood-brain barrier. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
The blood-brain barrier is a protective shield that allows nutrients to enter the brain while keeping harmful components in the bloodstream from passing into the brain. However, many factors can cause a leaky blood-brain barrier. This can allow harmful components to penetrate the blood-brain brain, ultimately causing inflammation and brain health issues. A leaky blood-brain barrier is associated with many mental health issues and neurological diseases, including anxiety, depression, brain fog, fatigue, Alzheimer’s disease, Parkinson’s disease, attention deficit hyperactivity disorder (ADHD), and schizophrenia. In the next article, we will discuss more natural ways which have been demonstrated to help fix a leaky blood-brain barrier and improve overall brain health.
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez
References:
The Star Academy. �How to Repair a Leaky Blood-Brain Barrier.� The Star Academy, The Star Academy, 16 Oct. 2018, thestaracademy.co.za/repair-leaky-blood-brain-barrier/.
Neurotransmitter Assessment Form
[wp-embedder-pack width=”100%” height=”1050px” download=”all” download-text=”” attachment_id=”52657″ /]
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue.
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance.
Neural Zoomer Plus for Neurological Disease
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention.
Food Sensitivity for the IgG & IgA Immune Response
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs.
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders.
Formulas for Methylation Support
XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download* All of the above XYMOGEN policies remain strictly in force.
According to the National Institute of Mental Health (NIH), approximately 20 percent of the population in the United States are diagnosed with a brain health issue every year, with depression and phobias being the most common types of diagnosable mental health issues. Moreover, the Centers for Disease Control and Prevention (CDC) reported that the suicide rate in the United States had reached 13 for every 100,000 people in 2014, which is the highest it had ever been since 1986. Scientists are starting to associate brain health issues with inflammation and its effects on the blood-brain barrier. �
The blood-brain barrier (BBB) is a connection of blood vessels that protect the brain against harmful free radicals in the bloodstream. However, the blood-brain barrier is so effective at protecting the brain from these “harmful” components in the bloodstream, that it can ultimately even prevent drugs and/or medications from penetrating this security system to treat brain health issues. A research study published in Psychotherapy and Psychosomatics demonstrated that the effectiveness of antidepressants is only slightly more effective compared to placebos in the treatment of mental health issues. �
What Causes a Leaky Brain?
Scientists continue to analyze ways to effectively penetrate the blood-brain barrier to treat brain health issues. Several research studies have also determined that inflammation may reduce the function of brain cells in the frontal lobe of people diagnosed with depression. Other scientists are starting to believe that antidepressants and medicines used to treat depression are ineffective because these don’t necessarily treat inflammation in the brain. When the blood-brain barrier is damaged or injured, harmful components can enter the brain through the bloodstream and cause neurodegenerative symptoms. �
A “leaky brain” is a well-known term that is increasingly being used to describe blood-brain barrier permeability. A variety of blood tests, including those that measure the levels of the proteins occludin and zonulin, can be used to determine a leaky brain. Immunoglobulin levels may also be measured. Scientists also measure the levels of a molecule, known as microRNA-155, which increases with inflammation. MicroRNAs (miRNAs) play the fundamental role of regulating immune reactions, with miR-155 as a biomarker for inflammation in the brain due to a leaky blood-brain barrier. According to various research studies, this molecule can cause small gaps to develop in the BBB which can ultimately cause inflammation and lead to a leaky brain. �
Several different research studies have also discussed how inflammation on the blood-brain barrier can eventually cause a leaky brain. Meanwhile, other research studies have demonstrated a link between inflammation and a variety of psychiatric disorders. Scientists also demonstrated that pro-inflammatory cytokines can increase and cause increased blood-brain barrier permeability. Many harmful components can also affect the structure of the mitochondria and the blood-brain barrier. Microglial cells in the brain may also trigger and activate the release of molecules that can further affect the BBB. �
Further evidence has also associated blood-brain barrier dysfunction with a leaky gut. Scientists have suggested treating an underlying leaky gut to help treat a leaky brain. According to research studies, intestinal permeability, or a �leaky gut�, may ultimately be associated with blood-brain barrier permeability. Bacteria, small molecules, and toxins in the blood are commonly found in celiac disease, a well-known problem caused by gluten sensitivity or intolerance. Although true celiac disease is considered to be rare, a leaky gut associated with celiac disease and brain health issues are considered to be more common. �
One research study discusses the connection between the gut microbiome, inflammation, and the integrity of the blood-brain barrier. The scientists of a different research study discussed how a variety of treatments used to help improve the biodiversity of the gut microbiome, including a healthy diet and lifestyle modifications, fecal microbiota transplantation, prebiotics, and probiotics, have demonstrated to support the function of the gut-brain axis. Scientists believe it will be possible to use the gut microbiome to improve brain and mental health issues as well as to prevent further complications. �
Too much inflammation may cause a variety of brain and mental health issues associated with blood-brain barrier permeability. Because many research studies have suggested the connection between a leaky gut and a leaky brain, maintaining a healthy gut microbiome may be an effective treatment for brain and mental health. Although the brain is protected by the blood-brain barrier, this security system can frequently prevent drugs and/or medications from being able to effectively treat many brain and mental health issues. Scientists have started working towards developing successful ways to allow treatments to penetrate the blood-brain barrier.� – Dr. Alex Jimenez D.C., C.C.S.T. Insight
As previously mentioned, the National Institute of Mental Health (NIH) states that about 20 percent of Americans are diagnosed with a mental health issue every year, where depression and phobias are considered to be the most common types of diagnosable brain health issues. Furthermore, the Centers for Disease Control and Prevention (CDC) recorded that the suicide rate in the United States reached 13 for every 100,000 people in 2014, which is the highest it has ever been since 1986. Scientists associate mental health issues with brain inflammation and how it causes a “leaky” blood-brain barrier. �
The blood-brain barrier (BBB) is a group of blood vessels that protect the brain against “harmful” components in the bloodstream. However, because the blood-brain barrier can be so effective at protecting the brain from these harmful free radicals in the bloodstream, it can ultimately prevent drugs and/or medications from successfully penetrating the BBB to treat mental health issues. Research studies published in Psychotherapy and Psychosomatics determined that the effectiveness of certain medicines can only be slightly more effective, compared to placebos, in the treatment of brain health issues. �
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez �
References:
Figeley, Melanie. �Do You Have A Leaky Brain?� Biotics NW Inc., Biotics NW Inc., 15 Jan. 2019, www.bioticsnw.com/blogs/news/do-you-have-a-leaky-brain.
Neurotransmitter Assessment Form
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �
Neural Zoomer Plus for Neurological Disease
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �
Food Sensitivity for the IgG & IgA Immune Response
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �
Formulas for Methylation Support
� XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
�
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download �
* All of the above XYMOGEN policies remain strictly in force. �
How often do you feel agitated, easily upset, and nervous between meals? How often do you have difficulty concentrating before eating? How often does your energy level drop in the afternoon? Inflammation associated with a leaky blood-brain barrier can cause a variety of brain health issues. Our brain is a complex organ that controls various structures and functions of our body, from our memory to our breathing, muscle movements, and hormones. �
Unfortunately, brain health issues are common in our society. According to the National Institute of Mental Health, approximately 20 percent of adults in the United States have a brain health issue and American adults spend about $113 billion on treatment every year. Additionally, these statistics don’t even include the treatment cost of autoimmune brain health issues, such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and autism. In the article below, we will discuss how inflammation is associated with a “leaky” blood-brain barrier and what you can do to improve a variety of brain health issues. �
“Leaky” Blood-Brain Barriers and Inflammation
Scientists have previously discussed how leaky gut syndrome, a well-known digestive health issue that affects the lining of the gastrointestinal (GI) tract, can be associated with various health issues. However, current research studies have shown that leaky gut syndrome may also be associated with a leaky blood-brain barrier or the breakdown of the blood-brain barrier.�The gut-brain connection ultimately suggests that a “leaky gut” may cause a “leaky brain”. �
Biomarkers using the proteins occludin and zonulin can help determine the presence of leaky gut syndrome and a leaky blood-brain barrier. Scientists have demonstrated that increased antibodies against occludin and zonulin are one way to determine leaky brain syndrome. Scientists have also demonstrated that a molecule known microRNA-155 can increase with inflammation. MicroRNA-155 can ultimately cause microscopic gaps to develop in the blood-brain barrier that permitted passage to “harmful” components. This permeability can trigger the brain’s immune system and cause brain inflammation. �
Various research studies from the cytokine model of cognitive function evaluated how brain inflammation and a leaky blood-brain barrier may be associated with cases of anxiety, depression, brain fog, and autoimmune brain health issues. By way of instance, scientists evaluated how inflammation can decrease the activation of brain cells in the frontal lobe of people with depression. In cases of brain inflammation, using drugs and/or medications, such as antidepressants, are frequently ineffective because they aren’t treating the underlying brain inflammation. If a patient suffers from anxiety, depression, brain fog, or autoimmune brain health issues, many healthcare professionals may suggest the presence of a leaky brain or a leaky blood-brain barrier. �
8 Steps to Improve a Leaky Blood-Brain Barrier
Inflammation and a leaky blood-brain barrier may ultimately cause a variety of bran health issues if it’s misdiagnosed and left untreated. If you suspect you may have anxiety, depression, brain fog, or autoimmune brain health issues due to inflammation associated with a leaky blood-brain barrier, it’s important to talk to a healthcare professional to receive proper diagnosis and treatment. Fortunately, there are steps you can take to improve a leaky blood-brain barrier:� �
Evaluate your blood-brain barrier by conducting labs for blood-brain barrier proteins, which can show BBB permeability, occludin and zonulin, which can show the antibodies against these proteins, homocysteine, which shows blood-brain barrier damage or injury through the increased levels of this amino acid, and brain agers like inflammation, which can accelerate the aging of the brain. High blood sugar may also show BBB permeability.
Determine a “leaky” blood-brain barrier by conducting microbiome labs. A “leaky gut” can cause a “leaky brain”. Understanding the gut-brain axis can help determine the presence of any underlying brain health issues. Bacterial imbalances and yeast overgrowths can cause neurological symptoms. By way of instance, anxiety and depression are associated with the bacteria known as Lactobacillus helveticus and Bifidobacterium longum.
Prevent yourself from eating foods, such as processed, refined and sugary foods as well as other toxins, that can cause a leaky blood-brain barrier.
Regulate stress for overall brain health. Research studies ultimately suggest that acute stress can increase the breakdown of the blood-brain barrier. Tai chi, yoga, and mindfulness meditation are several effective ways to help manage stress for the overall well-being of the human brain.
Take natural compounds, such as apigenin, baicalein, catechins, curcumin, luteolin, resveratrol, and rutin, that have all been suggested to reduce brain inflammation. However, because the correct dosage will be different for everyone, make sure to talk to a doctor before taking natural medicine.
Participate in exercise and physical activity that can help increase a brain-derived neurotrophic factor, BDNF, which helps promote brain health.
Reduce your consumption of alcohol. Alcohol can stress the brain and several research studies suggest that it can affect the blood-brain barrier.
Consider visiting a functional medicine practitioner to improve a leaky blood-brain barrier. While there’s no immediate fix for many chronic brain health issues, functional medicine customizes diagnostics and natural protocols based on your unique needs to help promote overall well-being.
The brain is protected by the blood-brain barrier, however, this security system can frequently prevent drugs and/or medications from being able to effectively treat brain health issues. Scientists have started working towards developing successful ways to allow treatments to penetrate the blood-brain barrier. Other research studies have demonstrated that the aging brain or neurodegeneration can cause the breakdown of the blood-brain barrier. However, research studies have demonstrated ways to restore and even reverse leaky blood-brain barriers and several brain health issues. Patients can take several steps to help improve a leaky blood-brain barrier. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
How often do you feel agitated, easily upset, and nervous between meals? How often do you have difficulty concentrating before eating? How often does your energy level drop in the afternoon? Inflammation associated with a leaky blood-brain barrier can cause a variety of brain health issues. Our brain is a complex organ that controls various structures and functions of our body, from our memory to our breathing, muscle movements, and hormones. �
Unfortunately, brain health issues are common in our society. According to the National Institute of Mental Health, approximately 20 percent of adults in the United States have a brain health issue and American adults spend about $113 billion on treatment every year. Additionally, these statistics don’t even include the treatment cost of autoimmune brain health issues, such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and autism. In the article above, we discussed how inflammation is associated with a “leaky” blood-brain barrier and what you can do to improve a variety of brain health issues. �
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez �
References:
Cole, William. �Signs You Might Have A �Leaky Brain� + What To Do About It.� Mindbodygreen, Mindbodygreen, 22 July 2015, www.mindbodygreen.com/0-20800/signs-you-might-have-a-leaky-brain-what-to-do-about-it.html.
Neurotransmitter Assessment Form
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �
Neural Zoomer Plus for Neurological Disease
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �
Food Sensitivity for the IgG & IgA Immune Response
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �
Formulas for Methylation Support
� XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
�
�
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download �
* All of the above XYMOGEN policies remain strictly in force. �
Blood vessels in the brain protect us from “harmful” components in the bloodstream. This is known as the blood-brain barrier. A Science Translational Medicine research study demonstrated how inflammation and cognitive impairment in a group of aging mice may be associated with the breakdown of the blood-brain barrier. In the following article, we will discuss how restoring the breakdown of the blood-brain barrier may improve overall brain health. �
What is a Leaky Blood-Brain Barrier?
Scientists determined that the breakdown of the blood-brain barrier can ultimately trigger a signaling protein in brain cells, known as astrocytes. They then created and evaluated a drug/medication that blocked the activation of the astrocytes, or the signaling protein known as the transforming growth factor-beta (TGF-beta). Following the treatment, the group of aging mice demonstrated reduced brain inflammation and improved cognitive function. �
“Our team of scientists associates the aging brain in the same way we associate neurodegeneration. The aging brain is characterized by loss of cognitive function and dead brain cells,” stated Daniela Kaufer, co-senior author and professor of integrative biology at the University of California, Berkeley. “However, our research study determined a different story about why the aging brain doesn’t function properly: It is because of brain fog,” she concluded. �
According to the research study, reducing inflammation and brain fog by restoring the breakdown of the blood-brain barrier can help improve the overall health and wellness of the aging brain. The results may also help scientists understand how cognitive impairment associated with inflammation and brain fog can accompany the aging brain and neurodegeneration as well as how the blood-brain barrier may be associated with improved brain function. �
Inflammation, Brain Fog, and Cognitive Impairment
A variety of research studies, including imaging research studies performed by Alon Friedman, co-senior author of Ben-Gurion University of the Negev in Israel and Dalhousie University in Canada, discussed the breakdown of the blood-brain barrier and how it can ultimately become less effective with age. A “leaky” blood-brain barrier can make it easier for “harmful” compounds to penetrate the brain and damage cells and tissue from the bloodstream. �
Kaufer and Friedman are also co-senior authors of another Science Translational Medicine research study that evaluated inflammation and brain fog in leaky blood-brain barriers. By way of instance, patients with Alzheimer’s disease may experience epileptic episodes, however, they may not be aware of them. Aging is a risk factor for Alzheimer’s disease and epilepsy where research studies have associated a connection between the two brain health issues. �
For the second research study, the team of scientists evaluated EEG readings from patients with Alzheimer’s disease and determined an EEG signature for what is ultimately known as paroxysmal slow wave events (PSWEs). From the EEGs, the scientists demonstrated how the rate of PSWEs appeared to match the level of cognitive impairment of the patients. In EEGs of patients with epilepsy, they demonstrated that PSWEs that happened between seizures matched cases of leaky blood-brain barriers. They determined the same match in aging mice, mice prone to Alzheimer’s disease, and rats with induced epilepsy. �
Further research studies in young rats also demonstrated that the blood-brain barrier can start to breakdown by introducing the protein albumin to the brain. According to the results, this ultimately caused an increased rate of PSWEs. Friedman and Kaufer also demonstrated that the protein albumin can penetrate the blood-brain barrier following trauma. The protein albumin can attach itself to the TGF-beta receptor of astrocytes and cause brain health issues. The team of scientists also concluded that a leaky blood-brain barrier may ultimately be a cause of inflammation, brain fog, and cognitive impairment. �
Leaky Blood-Brain Barrier Biomarkers
The scientists suggest that the results of the various research studies on leaky blood-brain barriers and brain health ultimately help offer a variety of biomarkers that could possibly help healthcare professionals recognize these type of problems by using MRI, which can detect leaky blood-brain barriers, and using EEG, which can detect abnormal brain rhythms. The outcome measures may also help develop the treatment that they may use as a way to restore a leaky blood-brain barrier to reduce and even reverse several of the brain health issues it may ultimately cause, including neurodegeneration. �
“Our team of scientists now use several biomarkers that demonstrate leaky blood-brain barriers, so healthcare professionals can choose patients for treatment,” stated professor Daniela Kaufer. “These research studies ultimately support the effects of leaky blood-brain barriers on a variety of brain health issues, including dementia and Alzheimer’s disease, associated with inflammation, brain fog, and cognitive impairment as well as offer possible results for future research studies,” stated Diego Gomez-Nicola, an associate professor of neuroscience at the University of Southampton in the United Kingdom, �
After the discoveries of the German scientist Paul Ehrlich during the late 1800s, a collection of experiments on a group of mice demonstrated how the brain regulates what to permit passage to and what to block from entering its blood vessels through the blood-brain barrier. The brain is ultimately protected by the blood-brain barrier, however, this security system can frequently prevent drugs and/or medications from being able to effectively treat brain health issues. Scientists have started working towards developing successful ways to allow treatments to penetrate the blood-brain barrier. Other research studies have demonstrated that by the aging brain, as well as neurodegeneration, can cause the breakdown of the blood-brain barrier. A leaky blood-brain barrier can ultimately cause inflammation, brain fog, and cognitive impairment. However, research studies have demonstrated ways to restore and even reverse leaky blood-brain barriers and several brain health issues. – Dr. Alex Jimenez D.C., C.C.S.T. Insight
Neurotransmitter Assessment Form
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �
Blood vessels in the brain protect us from “harmful” components in the bloodstream. This is known as the blood-brain barrier. A Science Translational Medicine research study demonstrated how inflammation and cognitive impairment in a group of aging mice may be associated with the breakdown of the blood-brain barrier. In the following article, we will discuss how restoring the breakdown of the blood-brain barrier may improve overall brain health. �
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez �
References:
Catharine Paddock, Ph.D. �Repairing Leaky Blood-Brain Barrier May Rejuvenate Brain Function.� Medical News Today, MediLexicon International, 6 Dec. 2019, www.medicalnewstoday.com/articles/327248.php#1.
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �
Neural Zoomer Plus for Neurological Disease
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �
Food Sensitivity for the IgG & IgA Immune Response
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
�
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �
Formulas for Methylation Support
XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
�
�
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download �
* All of the above XYMOGEN policies remain strictly in force. �
Our brain is a complex organ protected by our 7mm thick skull, a protective membrane, known as the meninges, and cerebrospinal fluid. These essential brain structures help protect the brain against physical damage or injury. Another brain structure that protects the brain from harm is the blood-brain barrier. The blood-brain barrier is the shield between the brain’s blood vessels and the cells in the brain’s tissue. While the skull, meninges, and cerebrospinal fluid protect the brain from physical damage or injury, the blood-brain barrier protects the brain from toxins and pathogens in the bloodstream. �
Moreover, the presence of the blood-brain barrier in the human brain was first discovered in the late 1800s by the German scientist Paul Ehrlich when he injected blue dye in the bloodstream of a group of mice during an experiment. The blue dye strained all of the animals’ tissues and organs with the exception of the brain and spinal cord. Although the outcome measures of the research study demonstrated the existence of the blood-brain barrier, it wasn’t until the 1960s that researchers were able to use much more powerful technologies to ultimately prove the presence of the blood-brain barrier in the human brain. �
Anatomy of the Blood-Brain Barrier
The main structure of the blood-brain barrier that helps protect the brain from toxins and pathogens in the bloodstream is known as the endothelial tight junction. The endothelial cells cover the inside of the blood vessels in the brain. The blood-brain barrier is such an effective security system because these endothelial cells in the blood vessels in the brain are connected extremely close to each other in “tight junctions”. The blood-brain barrier only permits small, fat-soluble molecules and several types of gases to pass freely between the blood vessels and the brain. Furthermore, bigger molecules, such as glucose and insulin, are only permitted passage through transporter proteins which act like “bouncers” that only open the doors for certain necessary molecules. �
The purpose of the blood-brain barrier is to protect the brain against toxins and pathogens circulating in the bloodstream that could cause brain health issues while also permitting passage to fundamental nutrients that are necessary for the brain. Other functions of the blood-brain barrier include regulating and managing consistent levels of nutrients, hormones, and water in the human brain. Changes in these may affect the homeostasis of the brain. �
The homeostasis of the brain can commonly be affected by bacterial infections, such as meningococcal disease. Meningococcal bacteria can attach to the endothelial cells of the blood vessels in the brain and cause the tight junctions to slightly open. This causes the blood-brain barrier to become more porous which can then permit passage to toxins and pathogens that can infect the brain tissue, leading to inflammation and sometimes even death. It�s also believed that the blood-brain barrier can decrease in a variety of other brain health issues. In multiple sclerosis, by way of instance, decreased blood-brain barrier function may permit white blood cells to pass into the brain and attack the structures that transmit messages from one neuron to another. �
Blood-Brain Barrier Treatment
The blood-brain barrier is so effective at protecting the brain from toxins and pathogens that it can even block necessary treatments from reaching the brain. The vast majority of potential drugs and/or medications that could help treat a variety of brain health issues aren’t able to readily penetrate the blood-brain barrier which may become a tremendous problem in treating neurological diseases. However, one possible way to penetrate the blood-brain barrier is to �trick� the security system into permitting passage to certain medicines. The blood-brain barrier can also be temporarily opened using ultrasound. �
One research study demonstrated that using ultrasound to temporarily open the blood-brain barrier in a mouse with Alzheimer�s disease can improve cognition and decrease toxic plaques in the brain. But most importantly, using ultrasound to temporarily open the blood-brain barrier didn�t damage or injure the brain. In another research study, researchers demonstrated that by temporarily opening the blood-brain barrier, ultrasound can permit the passage of drugs and/or medications into the brain, improving cognition and Alzheimer’s disease more than when using ultrasound or medicines alone. �
After the discoveries of the German scientist Paul Ehrlich during the late 1800s, a collection of experiments on a group of mice demonstrated how the brain regulates what to permit passage to and what to block from entering its blood vessels through the blood-brain barrier. The brain is ultimately protected by the blood-brain barrier, however, this security system can frequently prevent drugs and/or medications from being able to effectively treat brain health issues. Scientists have started working towards developing successful ways to allow treatments to penetrate the blood-brain barrier. Other research studies have demonstrated that by using ultrasound, the blood-brain barrier can be temporarily opened to permit passage for medicines to help treat a variety of brain health issues and neurological diseases, among other problems.�- Dr. Alex Jimenez D.C., C.C.S.T. Insight
Neurotransmitter Assessment Form
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �
Our brain is a complex organ that is protected by our 7mm thick skull, a protective membrane, known as the meninges, and cerebrospinal fluid. These essential brain structures ultimately help protect the brain against physical damage or injury. Another brain structure that protects the brain from harm is the blood-brain barrier. The blood-brain barrier is the shield between the brain’s blood vessels and the cells in the brain’s tissue. While the skull, meninges, and cerebrospinal fluid protect the brain from physical damage or injury, the blood-brain barrier protects the brain from toxins and pathogens in the bloodstream. �
Moreover, the presence of the blood-brain barrier in the human brain was first discovered in the late 1800s by the German scientist Paul Ehrlich when he injected blue dye in the bloodstream of a group of mice during an experiment. The blue dye strained all of the animals’ tissues and organs with the exception of the brain and spinal cord. Although the outcome measures of the research study demonstrated the existence of the blood-brain barrier, it wasn’t until the 1960s that researchers were able to use much more powerful technologies to ultimately prove the presence of the blood-brain barrier in the human brain. �
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez �
References:
Woodruff, Alan. �What Is the Blood-Brain Barrier?� Queensland Brain Institute, 11 Jan. 2018, qbi.uq.edu.au/brain/brain-anatomy/what-blood-brain-barrier.
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �
Neural Zoomer Plus for Neurological Disease
Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �
Food Sensitivity for the IgG & IgA Immune Response
Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �
Formulas for Methylation Support
� XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
�
For your convenience and review of the XYMOGEN products please review the following link. *XYMOGEN-Catalog-Download �
* All of the above XYMOGEN policies remain strictly in force. �
Our brain is protected by the blood-brain barrier, a connection of blood vessels that permits the passage of important nutrients while blocking other compounds. However, this security system is so efficient at guarding the brain that it can frequently prevent many drugs and/or medications from being able to effectively treat a variety of brain health issues. Scientists are working towards developing ways to allow treatments to penetrate the blood-brain barrier. �
The brain depends on a variety of precise communication signals from the nerve cells to perform many fundamental functions. And it’s surrounding environment must remain stable to successfully send and receive transmissions. During the late 1800s, the outcome measures of a research study on the brain started a collection of experiments that demonstrated how the brain ultimately protects itself from the natural changes that happen in the body. �
Understanding the Blood-Brain Barrier
Paul Ehrlich, a German scientist that later earned a Nobel Prize for developing a cure for syphilis, was first interested in the way that several different types of cells and tissues absorb various chemical dyes. The purpose of Ehrlich’s experiments was to discover new components that could protect the brain from other “harmful” compounds. However, Paul Ehrlich made an unexpectedly strange discovery throughout the course of his research studies. �
During a research study in 1885, Ehrlich injected blue dye into the bloodstream of a group of mice. The dye stained all of the animals’ organs blue with the exception of one essential organ: their brains. During a follow-up research study in 1913, the same blue dye previously used for the last experiment was directly injected into the brains of another group of mice. But this time, the animals’ brains turned blue while the other organs did not change color. �
While these experiments discovered the blood-brain barrier, there was no such equipment at the time that could have demonstrated the existence of this security system. As a matter of fact, it wasn’t until the 1960s that scientists detected the actual blood-brain barrier for the first time.� Scientists were able to see the detailed connection of blood vessels in the brain using a microscope that was about 5,000 times more powerful than the one Paul Ehrlich used. �
Scientists also discovered that, much like all of the other blood vessels in the body, the blood vessels in the brain are filled with endothelial cells which function as a sort of connection between the blood and vessel wall. Unlike all of the other blood vessels in the body, however, the endothelial cells in the brain are closely attached together which forms an almost impermeable barrier between the brain and the bloodstream: the blood-brain barrier. �
The blood-brain barrier permits the passage of nutrients and hormones, such as glucose and amino acids, while blocking “harmful” components, such as bacteria and toxins, from entering the brain. In order to demonstrate how the brain’s security system determines which molecules to permit passage to and which molecules to block, scientists injected certain compounds into the bloodstream of animals and then measured the amounts that arrived in the brain. �
Blood-Brain Barrier and Brain Health Issues
Over the course of several research studies, scientists demonstrated that certain compounds that are very small and/or fat-soluble, including anti-anxiety medicines, antidepressants, cocaine, alcohol, and many different types of hormones can slip through the endothelial cells of the blood-brain barrier. Bigger, more desirable molecules, including glucose and/or insulin, must be selectively carried across the blood-brain barrier by transporter proteins. �
Nerve cells found on either side of the blood-brain barrier are constantly communicating with one another regarding which molecules they should permit passage to and which components to block. By way of instance, nerve cells working hard within the brain may ultimately transmit signals to the blood vessels on either side of the blood-brain barrier for them dilate and allow nutrients to rapidly travel from the bloodstream to the nerve cells in need. �
However, several brain health issues, including injuries, underlying conditions, infections, and certain types of cancers, can cause the blood-brain barrier to become damaged and break down, resulting in tiny ruptures to the blood vessels in the brain. A variety of components that would normally be blocked by the blood-brain barrier can then be permitted passage, causing various problems for the brain, including a variety of neurological diseases. �
Moreover, outcome measures from several research studies suggest that the weakening of the blood-brain barrier may even be associated with a number of neurodegenerative disorders. For example, scientists suggest that a leaky blood-brain barrier permits the passage of too many white blood cells into the brains of patients with multiple sclerosis (MS). These cells attack the myelin sheath between the nerve cells, causing multiple sclerosis (MS) symptoms. �
Through new treatment technologies, scientists are starting to create new ways to open up the blood-brain barrier to allow drugs and/or medications to reach the brain without interfering with its functions. Although numerous challenges probably still lie ahead, many scientists are becoming hopeful that new knowledge on the structure of the blood-brain barrier will one day lead to better treatments for several of the most challenging brain health issues. �
After the discoveries Paul Ehrlich during the late 1800s, a collection of experiments started to help demonstrated how the brain regulates what to permit passage to and what to block from entering its blood vessels. The brain is protected by the blood-brain barrier, however, this security system can frequently prevent drugs and/or medications from being able to effectively treat brain health issues. Scientists have started working towards developing successful ways to allow treatments to penetrate the blood-brain barrier.�- Dr. Alex Jimenez D.C., C.C.S.T. Insight
Neurotransmitter Assessment Form
The following Neurotransmitter Assessment Form can be filled out and presented to Dr. Alex Jimenez. The following symptoms listed on this form are not intended to be utilized as a diagnosis of any type of disease, condition, or any other type of health issue. �
Our brain is protected by the blood-brain barrier, a connection of blood vessels that permits the passage of important nutrients while blocking other compounds. However, this security system is so efficient at guarding the brain that it can frequently prevent many drugs and/or medications from being able to effectively treat a variety of brain health issues. Scientists are working towards developing ways to allow treatments to penetrate the blood-brain barrier. �
The brain depends on a variety of precise communication signals from the nerve cells to perform many fundamental functions. And it’s surrounding environment must remain stable to successfully send and receive transmissions. During the late 1800s, the outcome measures of a research study on the brain started a collection of experiments that demonstrated how the brain ultimately protects itself from the natural changes that happen in the body. �
The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues or functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or disorders of the musculoskeletal system. Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We also make copies of supporting research studies available to the board and or the public upon request. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900.�
Curated by Dr. Alex Jimenez �
References:
Bates, Mary. �The Blood-Brain Barrier.� BrainFacts.org, 2 July 2014, www.brainfacts.org/brain-anatomy-and-function/anatomy/2014/blood-brain-barrier.
Additional Topic Discussion: Chronic Pain
Sudden pain is a natural response of the nervous system which helps to demonstrate possible injury. By way of instance, pain signals travel from an injured region through the nerves and spinal cord to the brain. Pain is generally less severe as the injury heals, however, chronic pain is different than the average type of pain. With chronic pain, the human body will continue sending pain signals to the brain, regardless if the injury has healed. Chronic pain can last for several weeks to even several years. Chronic pain can tremendously affect a patient’s mobility and it can reduce flexibility, strength, and endurance. �
Neural Zoomer Plus for Neurological Disease
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Dr. Alex Jimenez utilizes a series of tests to help evaluate neurological diseases. The Neural ZoomerTM Plus is an array of neurological autoantibodies which offers specific antibody-to-antigen recognition. The Vibrant Neural ZoomerTM Plus is designed to assess an individual�s reactivity to 48 neurological antigens with connections to a variety of neurologically related diseases. The Vibrant Neural ZoomerTM Plus aims to reduce neurological conditions by empowering patients and physicians with a vital resource for early risk detection and an enhanced focus on personalized primary prevention. �
Food Sensitivity for the IgG & IgA Immune Response
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Dr. Alex Jimenez utilizes a series of tests to help evaluate health issues associated with food sensitivities. The Food Sensitivity ZoomerTM is an array of 180 commonly consumed food antigens that offers very specific antibody-to-antigen recognition. This panel measures an individual�s IgG and IgA sensitivity to food antigens. Being able to test IgA antibodies provides additional information to foods that may be causing mucosal damage. Additionally, this test is ideal for patients who might be suffering from delayed reactions to certain foods. Utilizing an antibody-based food sensitivity test can help prioritize the necessary foods to eliminate and create a customized diet plan around the patient�s specific needs. �
Gut Zoomer for Small Intestinal Bacterial Overgrowth (SIBO)
Dr. Alex Jimenez utilizes a series of tests to help evaluate gut health associated with small intestinal bacterial overgrowth (SIBO). The Vibrant Gut ZoomerTM offers a report that includes dietary recommendations and other natural supplementation like prebiotics, probiotics, and polyphenols. The gut microbiome is mainly found in the large intestine and it has more than 1000 species of bacteria that play a fundamental role in the human body, from shaping the immune system and affecting the metabolism of nutrients to strengthening the intestinal mucosal barrier (gut-barrier). It is essential to understand how the number of bacteria that symbiotically live in the human gastrointestinal (GI) tract influences gut health because imbalances in the gut microbiome may ultimately lead to gastrointestinal (GI) tract symptoms, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders. �
Formulas for Methylation Support
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Proudly,�Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
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If you are a patient of Injury Medical & Chiropractic�Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
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