Back Clinic Functional Medicine Team. Functional medicine is an evolution in the practice of medicine that better addresses the healthcare needs of the 21st century. By shifting the traditional disease-centered focus of medical practice to a more patient-centered approach, functional medicine addresses the whole person, not just an isolated set of symptoms.
Practitioners spend time with their patients, listening to their histories and looking at the interactions among genetic, environmental, and lifestyle factors that can influence long-term health and complex, chronic disease. In this way, functional medicine supports the unique expression of health and vitality for each individual.
By changing the disease-centered focus of medical practice to this patient-centered approach, our physicians are able to support the healing process by viewing health and illness as part of a cycle in which all components of the human biological system interact dynamically with the environment. This process helps to seek and identify genetic, lifestyle, and environmental factors that may shift a person’s health from illness to well-being.
According to research studies, stress management can promote methylation support. High levels psychological and physiological stress can increase the production of the catecholamines epinephrine and norepinephrine, both of which depend on methylation for their biosynthesis, metabolism, and excretion. DNA methylation activity utilizes SAMe and it can lower the availability of this methyl donor for other processes. Stress management is, therefore, a fundamental treatment option to promote methylation support.
Stress can also affect DNA methylation status through different mechanisms rather than through the utilization of methyl donors. Although a variety of research studies have been conducted regarding the effects of stress on methylation, our understanding of the complex association between stress management and methylation support is still tremendously limited. Methylation of the promoter genes for glucocorticoid, an essential regulator of the HPA axis and stress response, has been demonstrated to be affected differently through various states of stress, including early-life stress, post-traumatic stress disorder, or PTSD, and chronic fatigue syndrome.
How Stress Affects Methylation
We do understand, however, that stress-mediated epigenetic “priming” through methylation during fundamental developmental stages has been associated with a variety of health issues. By way of instance, and as we’ve previously discussed, low levels of maternal nurturing can affect DNA methylation status in the glucocorticoid receptor promoter and gene expression. This ultimately suggests that traumatic experiences, especially during essential stages of development, may “prime” high levels of stress. Several researchers believe that the connection between stress and methylation may explain the association of health issues, such as asthma.
Furthermore, research studies determined that prenatal maternal stress, as evaluated after the January 1998 Quebec ice storm, correlates with increased central adiposity and BMI in offspring at age 13 1?2. These changes are regulated through DNA methylation. Traumatic childhood experiences, including maltreatment, and parental death or desertion, outside of the prenatal and perinatal stages of development can also affect methylation of the promoter genes for glucocorticoid, associated with increased cortisol production.
Research studies have also demonstrated that acute and chronic stress can increase circulating inflammatory factors, including IL-1?, CRP, and IL-6, which are commonly regulated through the NLRP3 inflammasome. This may be a considerable way in which stress affects epigenetic changes. The effects of inflammation on DNA methylation status and activity have been discussed in previous articles. Doctors and functional medicine practitioners can recommend stress management techniques for methylation support.
Stress is a natural response to any type of demand or threat, it is the human body’s way of protecting you. However, chronic stress can cause a variety of health issues and recent research studies have demonstrated that stress can even affect an individual’s DNA methylation status. Doctor and functional medicine practitioners can recommend several stress management techniques, whether through nutrition and/or lifestyle modifications, to help promote methylation support. According to the article above, stress can affect methylation in several ways.
Dr. Alex Jimenez D.C., C.C.S.T. Insight
Smoothies and Juices for Methylation Support
While many healthcare professionals can recommend nutritional guidelines and lifestyle modifications to improve methylation support, there are several options you can try yourself at home. As described above, methylation support supplementation should be determined by a healthcare professional. Smoothies and juices are a fast and easy way to include all the necessary nutrients you need for methylation support without any side-effects. The smoothies and juices below are part of the Methylation Diet Food Plan.
Sea Green Smoothie Servings: 1 Cook time: 5-10 minutes � 1/2 cup cantaloupe, cubed � 1/2 banana � 1 handful of kale or spinach � 1 handful of Swiss chard � 1/4 avocado � 2 teaspoons spirulina powder � 1 cup water � 3 or more ice cubes Blend all ingredients in a high-speed blender until completely smooth and enjoy!
Berry Bliss Smoothie Servings: 1 Cook time: 5-10 minutes � 1/2 cup blueberries (fresh or frozen, preferably wild) � 1 medium carrot, roughly chopped � 1 tablespoon ground flaxseed or chia seed � 1 tablespoons almonds � Water (to desired consistency) � Ice cubes (optional, may omit if using frozen blueberries) Blend all ingredients in a high-speed blender until smooth and creamy. Best served immediately!
Sweet and Spicy Juice Servings: 1 Cook time: 5-10 minutes � 1 cup honeydew melons � 3 cups spinach, rinsed � 3 cups Swiss chard, rinsed � 1 bunch cilantro (leaves and stems), rinsed � 1-inch knob of ginger, rinsed, peeled and chopped � 2-3 knobs whole turmeric root (optional), rinsed, peeled and chopped Juice all ingredients in a high-quality juicer. Best served immediately!
Ginger Greens Juice Servings: 1 Cook time: 5-10 minutes � 1 cup pineapple cubes � 1 apple, sliced � 1-inch knob of ginger, rinsed, peeled and chopped � 3 cups kale, rinsed and roughly chopped or ripped � 5 cups Swiss chard, rinsed and roughly chopped or ripped Juice all ingredients in a high-quality juicer. Best served immediately!
Zesty Beet Juice Servings: 1 Cook time: 5-10 minutes � 1 grapefruit, peeled and sliced � 1 apple, washed and sliced � 1 whole beet, and leaves if you have them, washed and sliced � 1-inch knob of ginger, rinsed, peeled and chopped Juice all ingredients in a high-quality juicer. Best served immediately!
Protein Power Smoothie Serving: 1 Cook time: 5 minutes � 1 scoop protein powder � 1 tablespoon ground flaxseed � 1/2 banana � 1 kiwi, peeled � 1/2 teaspoon cinnamon � Pinch of cardamom � Non-dairy milk or water, enough to achieve desired consistency Blend all ingredients in a high-powered blender until completely smooth. Best served immediately!
ProLon� Fasting Mimicking Diet
Balanced methylation support can be achieved through proper nutrition. The ProLon� fasting mimicking diet offers a 5-day meal program which has been individually packed and labeled to serve the foods you need for the FMD in precise quantities and combinations. The meal program is made up of ready-to-eat or easy-to-prepare, plant-based foods, including bars, soups, snacks, supplements, a drink concentrate, and teas. The products are scientifically formulated and great tasting. Before starting the ProLon� fasting mimicking diet, 5-day meal program, please make sure to talk to a healthcare professional to find out if the FMD is right for you. The ProLon� fasting mimicking diet can help promote methylation support, among a variety of other healthy benefits.
Many healthcare professionals can recommend a variety of treatment options to help with stress management and help prevent health issues associated with DNA methylation. Proper nutrition and lifestyle habits, can improve methylation. The scope of our information is limited to chiropractic, musculoskeletal and nervous health issues as well as functional medicine articles, topics, and discussions. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .
Curated by Dr. Alex Jimenez
Additional Topic Discussion: Acute Back Pain
Back pain is one of the most prevalent causes of disability and missed days at work worldwide. Back pain attributes to the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience back pain at least once throughout their life. Your spine is a complex structure made up of bones, joints, ligaments, and muscles, among other soft tissues. Injuries and/or aggravated conditions, such as herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief.
Formulas for Methylation Support
XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly, Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
For your convenience and review of the XYMOGEN products please review the following link.*XYMOGEN-Catalog-Download
* All the above XYMOGEN policies remain strictly in force.
People from all walks of life can have hormonal imbalances and don�t realize it. Medical tests for abnormal thyroid function don�t always pick up on a thyroid that isn’t working correctly.
Adrenals have the same issues. When overworked, the hormonal imbalance that follows can become a nightmare. Fortunately, there are excellent natural remedies for hormonal imbalance.
Hormones Not Balanced
Glands that are under-producing will have some symptoms that are different from glands that are over-producing. However, some symptoms are shared across the board. If you notice that you experience several of these symptoms, it could point to a hormonal imbalance:
Weight loss or gain (without trying or doing anything different)
Swelling
Confusion, difficulty finding the �right� word, lack of mental clarity
Your chiropractor, naturopath, or specialist can help you determine if you have a hormonal imbalance. Many medical doctors tend to prescribe medications, but in most cases, the problem can be corrected through natural means. These three treatments are very beneficial in treating hormonal imbalances in the body. They can be done separately or combined for added benefits.
Herbs and Essential Oils
There are several herbs and essential oils that are exceptional when it comes to balancing hormones. Ashwagandha tops the list for treating overactive or sluggish thyroid as well as overtaxed adrenals. You can take it as a tablet or capsule, in powder form, or as a liquid. Mixing � to � teaspoons of powder into some milk with honey and taking just before bedtime can help you sleep as well as calm your stress and balance your hormones.
Several essential oils like clary sage, lavender, and sandalwood help reduce stress and promote a sense of wellbeing. Hormonal balance is a natural result. To use essential oils, put 3 to 5 drops in a diffuser and breathe it in.
Nutrition Balances Hormones
Hormonal imbalance is often the result of stress, whether it is emotional stress from difficulties in life or physical stress from poor health habits like not getting enough sleep and not maintaining a healthy diet. Omega 3 and six fatty acids are vital for everything from heart health to vibrant skin to hormonal balance. Extra nutrients you should be getting include vitamin D, B complex, and magnesium. If you aren�t getting enough in the foods that you eat, then consider supplements. Yes, it�s that important.
You can also give your body a significant boost by taking probiotics and enjoying the marvelous healing properties of bone broth. Bone broth is available in powder or liquid � or you can make it yourself. It packs a serious nutritional punch so incorporating it into your diet is a brilliant move.
Chiropractic Balances Hormones
Chiropractic care is an excellent treatment for hormonal imbalance. It goes right to the heart of many of the factors that cause the body to get out of balance and treats the problem at its root.
It helps to relieve stress in the body and reduce or eliminate pain, both of which can contribute to hormonal imbalances. It is one of the best natural treatments for hormonal imbalance because it brings the body itself back into balance.
What�s more, the whole-body approach that chiropractic offers means that you get recommendations on healthy eating, exercise, and positive lifestyle changes. All of these things work together to balance your body and balance your hormones for a healthier, happier you.
Research has given us even more reasons to eat our veggies. Several studies have revealed that certain types of vegetables, specifically those known as cruciferous vegetables, have properties that could make them useful in preventing cancer.
What are Cruciferous Vegetables?
Some of the crunchiest, tastiest vegetables belong to the Cruciferae family. Typically cool weather vegetables, they are most notably characterized by four petal flowers somewhat resembling a cross.
These flower buds or the leaves are the parts of these plants that are most often consumed. However, the seeds or roots of some of these vegetables are also edible. Incorporating some of these cruciferous vegetables into your diet may help lower your risk for cancer:
Broccoli
Cabbage
Wasabi
Collard greens
Bok choi
Brussels sprout
Arugula
Cauliflower
Mustard (leaves and seeds)
Turnips
Horseradish
Rutabaga
Kale
Radish
Watercress
What is the Link Between Cruciferous Vegetables and Cancer?
Cruciferous vegetables are packed with nutrients that are believed to lower a person�s risk for several types of cancers, including prostate cancer, colorectal cancer, lung cancer, and breast cancer. This includes the carotenoids zeaxanthin, lutein, and beta-carotene as well as folate and vitamins C, E, and K. They are also rich in minerals and an excellent source of fiber which is well known for preventing colorectal cancer.
This group of vegetables is also a good dietary source of glucosinolates which also has cancer-fighting properties. When intact, the glucosinolates are not effective, but when they are broken down through chewing, processing, and pests, they then make contact with the myrosinase enzyme and initiate a process that releases specific chemicals that can prevent cancer.
How Cruciferous Vegetables Prevent Cancer
There are three primary ways that cruciferous vegetables can prevent cancer. Researchers have found substantial evidence that shows when they are part of a healthy, clean, low-fat diet, a person�s risk of cancer can be decreased.
Glucosinolates � These are chemicals that contain sulfur and are present in all cruciferous vegetables, giving them their trademark bitter flavor and pungent aroma. When this substance is broken down by chewing, preparation, or digestion, it forms certain compounds (indole-3-carbinol and sulforaphane) that scientists have identified as having �anticancer properties.� They do this by impeding the development or growth of cancer. Studies have looked at this effect on mice and rats and found that it is particularly useful in specific organs. Researchers are also looking at other ways the substances can prevent cancer. When working in the body, they:
Have anti-inflammatory properties
Aid in preventing DNA damage to cells
Inhibit the formation of blood vessels in tumors
Are antibacterial and antiviral
Inhibit the migration of tumor cells, thus halting metastasis
Cause cancerous cells to die
Aid in causing carcinogens to become inactiveBioactive components � Some studies have shown that the bioactive components of these veggies can affect the biomarkers of processes related to cancer in the human body such as decreasing abnormal cell growth. Genetic encoding of glutathione S-transferase � Glutathione S-transferase is an enzyme that helps the body metabolize and eliminate isothiocyanates. This is important because isothiocyanates prevent the activation of carcinogens, increase the speed at which the carcinogens are removed from the body, and counteract the dangerous effects of active carcinogens.
Best Ways to Consume Cruciferous Vegetables
Cruciferous vegetables are at their most nutritious and have the greatest cancer-fighting properties when they are raw. When the vegetables are chopped and chewed they release the most cancer-fighting chemicals. Likewise, when they are cooked, they lose a great deal of those properties. Steaming or cooking the vegetables very lightly for less than 5 minutes will allow them to retain some of those cancer-fighting properties.
Dr. Alex Jimenez Explains Methylation Status, Inflammation and Oxidative Stress
As previously mentioned in the past series of articles, doctors can use a variety of clinical assessments to evaluate the methylation status of their patients. Although no assessment method or technique can accurately determine a patient’s methylation activity, current assessments can provide a better understanding of methylation-related genetic polymorphisms, nutrient status, methylation-related neurotransmitters and neurotransmitter metabolites, amino acids, hormones and metabolites, oxidative stress, and detoxification load. Each of these processes and substances can help doctors and patients understand their methylation status.
Understanding Methylation Status
Various assessment methods and techniques, including measures utilized to determine DNA methylation status, are usually exclusive to research studies and are not yet readily available to doctors. Until methylation status assessments become more widely available, further diagnosis is still required to understand diseases, especially since conflicting outcome measures have been found in research studies on the various methodologies. Although methods and techniques from research studies have rapidly started to evolve, patterns of DNA methylation status in humans across cells, tissues, age, populations, environmental factors like nutrition and lifestyle modifications, as well as disease, have only just started to become more widely recognized by researchers and doctors.
It is fundamental that we focus on a variety of these indicators and that we become aware of the restrictions of our interpretations and their misunderstood factors. Plasma homocysteine, by way of instance, can decrease as methylation activity increases, but, it can also decrease when oxidative stress levels increase, regardless if methylation activity increases. However, as we�ve previously mentioned, only several SNPs have known, quantifiable alterations in enzymatic function and their overall outcome measures on methylation remain unknown. Doctors must rely on a variety of clinical assessments to evaluate the methylation status of their patients. In the following articles, we will continue to discuss methylation status assessment options available to doctors for patients.
Understanding Inflammation
Inflammation increases the production of cytokine which can alter a patient’s methylation status in a variety of ways. DNA methylation activity is also tremendously affected by inflammation-related signaling molecules. Cytokines, chemokines, free radicals, prostaglandins, growth factors, and matrix metalloproteinases, are produced during inflammation, altering epigenetic changes in DNA methylation activity. IL-1?, by way of instance, suppresses p53 expression, creating a more favorable environment for tumorigenesis. NF?B is a central transcription factor triggered by inflammation which also regulates the expression of more than 400 genes.
Moreover, it directly regulates NK?B-dependent histone demethylase which in turn regulates the fate and transdifferentiation of tumor cells. IL-6, another inflammatory signaling molecule, regulates the activity of DNMTs, microRNAs and histone methyltransferases which affect the epigenetics of p53 tumor suppressor genes by reducing expression. TNF-alpha increases in mitotically-preserved and region-specific DNA methylation activity in a way that seems to include impaired cellular differentiation and renewal. In vitro outcome measures suggest that inflammation may also promote the production of methyl radicals which trigger DNA methylation activity in normal, unmethylated tumor suppressor genes, causing gene silencing and carcinogenesis.
Inflammation can also cause a metabolic milieu that drains methylation resources, by way of instance, through the dysregulation of glucose homeostasis. Pro-inflammatory molecules can also alter insulin signaling in peripheral tissues, reducing inflammatory mediators that promote insulin signaling. Insulin dysfunction and hyperglycemia promote elevated levels of oxidative stress which triggers increased utilization of glutathione and depleted homocysteine, methionine and SAMe. Furthermore, DNA methylation patterns affecting metabolism and inflammation were identified in adipose tissue from subjects with type 2 diabetes.
Understanding Oxidative Stress
Oxidative stress is closely associated with inflammation. States of elevated, or chronic, oxidative stress can negatively alter DNA methylation through two mechanisms. First, oxidative stress increases the demand for glutathione synthesis, which pulls homocysteine towards transulfuration pathways, at the expense of methylation pathways and SAMe formation. Second, oxidative stress and increased hydroxyl radical formation can damage DNA and change the ability of DNA methyltransferase enzymes to appropriately methylate DNA. This is one of the most common causes of global DNA hypomethylation and specific areas of hypermethylation.
DNA guanine nucleotides are main regions of DNA damage caused by oxidative stress, which is why they are frequently utilized as a biomarker for DNA-level oxidative stress, or 8OHdG. Generally, guanine functions as a hydrogen bond acceptor to promote the creation of methyl binding protein, or MBP, DNA complexes. However, oxidation of guanine considerably decreases MBP binding when combined to the 5- methylcytosine nucleotide. Additionally, 5-methylcytosine, or 5-mC, may also experience oxidation or hydroxylation, forming 5-hydroxymethylcytosine, or 5-hmC, through oxidative stress. This can tremendously affect interactions with DNA-proteins that can prevent their binding affinity to MBPs, leading to potentially heritable epigenetic alterations.
The methods and techniques commonly utilized to determine DNA methylation can’t distinguish between 5-mC and 5-hmC, which may prove to be an essential distinction, especially in the brain, where most DNA hydroxymethylation can be found. There is outcome measures which demonstrate that acute psychological stress can increase DNA hydroxymethylation in the hippocampal glucocorticoid receptor gene. This epigenetic alteration can lead to the development of neuropsychiatric and neurodegenerative disorders. Aging is also associated with increases in 5-hmC in the brain which may be prevented by caloric restriction and antioxidant upregulation.
A variety of research studies have found that DNA methylation can be affected by inflammation, most commonly caused due to oxidative stress. Increasing outcome measures have also demonstrated that methylation activity may become affected in response to both nutritional and environmental influences. Alterations in DNA methylation caused by inflammation and oxidative stress can lead to problems in gene expression, increasing the potential risk of disease. Understanding the effects of inflammation due to oxidative stress is fundamental when investigating epigenetic mechanisms. DNA methylation assessments based on inflammation and oxidative stress can help patients regulate their overall health and wellness.
Dr. Alex Jimenez D.C., C.C.S.T. Insight
Smoothies and Juices for Methylation Support
While many healthcare professionals can recommend nutritional guidelines and lifestyle modifications to improve methylation support, there are several options you can try yourself at home. As described above, methylation support supplementation should be determined by a healthcare professional. Smoothies and juices are a fast and easy way to include all the necessary nutrients you need for methylation support without any side-effects. The smoothies and juices below are part of the Methylation Diet Food Plan.
Sea Green Smoothie Servings: 1 Cook time: 5-10 minutes � 1/2 cup cantaloupe, cubed � 1/2 banana � 1 handful of kale or spinach � 1 handful of Swiss chard � 1/4 avocado � 2 teaspoons spirulina powder � 1 cup water � 3 or more ice cubes Blend all ingredients in a high-speed blender until completely smooth and enjoy!
Berry Bliss Smoothie Servings: 1 Cook time: 5-10 minutes � 1/2 cup blueberries (fresh or frozen, preferably wild) � 1 medium carrot, roughly chopped � 1 tablespoon ground flaxseed or chia seed � 1 tablespoons almonds � Water (to desired consistency) � Ice cubes (optional, may omit if using frozen blueberries) Blend all ingredients in a high-speed blender until smooth and creamy. Best served immediately!
Sweet and Spicy Juice Servings: 1 Cook time: 5-10 minutes � 1 cup honeydew melons � 3 cups spinach, rinsed � 3 cups Swiss chard, rinsed � 1 bunch cilantro (leaves and stems), rinsed � 1-inch knob of ginger, rinsed, peeled and chopped � 2-3 knobs whole turmeric root (optional), rinsed, peeled and chopped Juice all ingredients in a high-quality juicer. Best served immediately!
Ginger Greens Juice Servings: 1 Cook time: 5-10 minutes � 1 cup pineapple cubes � 1 apple, sliced � 1-inch knob of ginger, rinsed, peeled and chopped � 3 cups kale, rinsed and roughly chopped or ripped � 5 cups Swiss chard, rinsed and roughly chopped or ripped Juice all ingredients in a high-quality juicer. Best served immediately!
Zesty Beet Juice Servings: 1 Cook time: 5-10 minutes � 1 grapefruit, peeled and sliced � 1 apple, washed and sliced � 1 whole beet, and leaves if you have them, washed and sliced � 1-inch knob of ginger, rinsed, peeled and chopped Juice all ingredients in a high-quality juicer. Best served immediately!
Protein Power Smoothie Serving: 1 Cook time: 5 minutes � 1 scoop protein powder � 1 tablespoon ground flaxseed � 1/2 banana � 1 kiwi, peeled � 1/2 teaspoon cinnamon � Pinch of cardamom � Non-dairy milk or water, enough to achieve desired consistency Blend all ingredients in a high-powered blender until completely smooth. Best served immediately!
ProLon� Fasting Mimicking Diet
Balanced methylation support can be achieved through proper nutrition. The ProLon� fasting mimicking diet offers a 5-day meal program which has been individually packed and labeled to serve the foods you need for the FMD in precise quantities and combinations. The meal program is made up of ready-to-eat or easy-to-prepare, plant-based foods, including bars, soups, snacks, supplements, a drink concentrate, and teas. The products are scientifically formulated and great tasting. Before starting the ProLon� fasting mimicking diet, 5-day meal program, please make sure to talk to a healthcare professional to find out if the FMD is right for you. The ProLon� fasting mimicking diet can help promote methylation support, among a variety of other healthy benefits.
Many doctors and functional medicine practitioners may recommend higher doses of methyl donors in several patients, however, further research studies are needed to determine the proper amount of methylation supplementation. The scope of our information is limited to chiropractic, musculoskeletal and nervous health issues as well as functional medicine articles, topics, and discussions. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .
Curated by Dr. Alex Jimenez
Additional Topic Discussion: Acute Back Pain
Back pain is one of the most prevalent causes of disability and missed days at work worldwide. Back pain attributes to the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience back pain at least once throughout their life. Your spine is a complex structure made up of bones, joints, ligaments, and muscles, among other soft tissues. Injuries and/or aggravated conditions, such as herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief.
Formulas for Methylation Support
XYMOGEN�s Exclusive Professional Formulas are available through select licensed health care professionals. The internet sale and discounting of XYMOGEN formulas are strictly prohibited.
Proudly, Dr. Alexander Jimenez makes XYMOGEN formulas available only to patients under our care.
Please call our office in order for us to assign a doctor consultation for immediate access.
If you are a patient of Injury Medical & Chiropractic Clinic, you may inquire about XYMOGEN by calling 915-850-0900.
For your convenience and review of the XYMOGEN products please review the following link.*XYMOGEN-Catalog-Download
* All the above XYMOGEN policies remain strictly in force.
Fred Foreman is a basketball coach who depends on his overall health and wellness to be able to engage in his everyday responsibilities. As a result, coach Foreman started the 6 Day Detox Program from Xymogen, designed to help renew and enhance the human body’s cleansing and detoxification capabilities.
Fred Foreman discusses his experience with the 6 Day Detox Program, describing the benefits he developed as well as the effort he had to implement, to support his overall health and wellness through the detox. Fred Foreman feels a great sense of fulfillment with the 6 Day Detox Program and he encourages other people, who also wish to improve their well-being, to detox their body. Coach Foreman highly recommends the 6 Day Detox Program as an alternative treatment choice for overall health and wellness.
Injury Medical & Chiropractic Clinic
We are blessed to present to you El Paso�s Premier Wellness & Injury Care Clinic.
As El Paso�s Chiropractic Rehabilitation Clinic & Integrated Medicine Center, we passionately are focused on treating patients after frustrating injuries and chronic pain syndromes. We focus on improving your ability through flexibility, mobility and agility programs tailored for all age groups and disabilities.
We want you to live a life filled with more energy, positive attitude, better sleep, less pain, proper body weight and educated on how to maintain this way of life.
I assure you, I will only accept the best for you�
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Can nutritional epigenetics influence how we age and our longevity? El Paso, Tx. Dr. Jimenez presents data on how nutrition can influence longevity and how we age.
Longevity or our length of life is dictated by complex factors which include our genetic blueprint, age, health, and environment. This includes nutrition.
Gene-nutrient interactions are, partly responsible for regulating metabolic processes that begin and develop conditions like obesity, metabolic syndrome, cardiovascular disease, and cancer.
A mechanism of nutrient-gene interaction is the epigenetic involvement of inherited patterns of changes, that are maintained by other mechanisms in DNA, Fig. 1a
Although still not fully proven but on the right track was that the availability of folate improved the regeneration of the adult central nervous system after injury through an epigenetic mechanism.
Epigenetic Aging
During the last couple of years, we witnessed a remarkable increase in the number of studies addressing the relationship between epigenetic alterations and aging. Still in its infancy, and still focusing mainly on brain aging, this research clearly indicated that epigenetic mechanisms are not only responsible, in part, for the aging process but they are also dynamically related with memory formation and maintenance.
Penner MR, Roth TL, Barnes CA, Sweatt JD. An epigenetic hypothesis of aging-related cognitive dysfunction. Front Aging Neurosci 2010; 2:9.
The manipulation of the epigenome for memory improvement became possible through changes in histone acetylation.
The Link: Nutrition & Longevity
Research to complete the chain of nutrition to epigenetic changes to how we age is still ongoing.
Present knowledge of the epigenetic roles in nutrition having to do with longevity/aging relies on the structure of three components:
Nutritionally guided epigenetic modification
Age-related epigenetic changes
Comprehensive knowledge of both of these components
The first two are being developed quickly, but the third is the most demanding in terms of design, time, allocation, and cost. This takes more time. But technology/humanity is moving along at a quick pace, as well, because at the end of the day we all want to be healthy.
Therefore, Nutritional intervention, when applied at critical periods (e.g., embryonic and fetal development) is having a profound effect as to how the epigenome gets shaped.
When considering the beginning of chronic disease/s, being able to fight disease/s with food sounds like a win-win. If epigenetic/genomic nutrition can help in figuring out what we need to beat disease/s, then let’s go!
Family In Kitchen Making Morning Breakfast Together
How does epigenetic and personalized nutrition contribute to optimal health?
Most of us know about unhealthy food how it affects our bodies. They
Slow Down Metabolism
Add Weight
Clog and harden arteries etc.
But now there are foods and food elements that can help us in a way and comes from a place we might not of thought of, and that is our DNA.
Nutriepigenomics examines connections between diet and biomarkers that can be attached or removed from our DNA. This turns our genes on or off.
New studies are showing that certain foods or supplements can adjust the expression of our genes, which can influence our health.
Nutritional genomics is revolutionizing both clinical and public health nutritional practices:
Diet, exercise, and environmental exposure are all elements that have shown a role in switching genes on and off through epigenetics. Adjusting lifestyle factors can control the potential to reduce disease and have a positive impact on our health.
Health professionals from all over are beginning to incorporate epigenetics into their practice aiming to provide more specialized and individualized treatment plans.
�Layering information such as diet, lifestyle, environmental factors, family history, symptoms, and diagnoses along with epigenetics can help guide someone to a state of optimized health,� said Kristy Hall, MS, RNCP, ROHP, a board certified functional nutritionist and founder of Living Well Nutrition who uses epigenetic testing, nutrition counseling, and a multifaceted approach to better provide for her clients.
The upper DNA molecule differs from the lower DNA molecule at a single base-pair location (a C/A polymorphism)
Nutritional genetics or nutrigenetics involves the identification, classification, and characterization of human genetic variation that modifies nutrient metabolism/ utilization and food tolerances Fig1.
IOM. Nutrigenomics and beyond: Informing the future. Washington, DC: The National Academies Press; 2007.
Application: Genetic & Epigenetics
Nutrients, for example, pharmaceuticals, are powerful effectors of genome expression and stability, and these gene-nutrient interactions can be optimized for disease prevention.
Individualized Nutrition
The promise of nutritional engineering for optimal health through diet is still ongoing, but the public is holding positive expectations, as is evidenced by the use of dietary supplements.
Scientific research is showing that nutrients in different foods and supplements we eat may be able to adjust or reverse heritable changes. This evidence can be used in making better lifestyle choices.
Blueberries are incredibly high in antioxidants and it�s thought that this �superfood� can epigenetically reduce DNA damage, thereby protecting humans against cancer and possibly even slow aging. Blueberry juice and vitamin C have been shown to be potential methylation inhibitors for the MTHFR gene and the DNMT1 gene in humans.
Kim, M., Na, H., Kasai, H., Kawai, K., Li, Y.-S., & Yang, M. (2017). Comparison of Blueberry (Vaccinium spp.) and Vitamin C via Antioxidative and Epigenetic Effects in Human. Journal of Cancer Prevention, 22(3), 174�181.
Learning about what we eat and what it does to our bodies, especially potential epigenetic impact, is just one step closer to optimal health.
IFM's Find A Practitioner tool is the largest referral network in Functional Medicine, created to help patients locate Functional Medicine practitioners anywhere in the world. IFM Certified Practitioners are listed first in the search results, given their extensive education in Functional Medicine
