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Gut and Intestinal Health

Back Clinic Gut and Intestinal Health. The health of an individual’s gut determines what nutrients are absorbed along with what toxins, allergens, and microbes are kept out. It is directly linked to the health of the whole body. Intestinal health could be defined as optimal digestion, absorption, and assimilation of food. But this is a job that depends on many other factors. More than 100 million Americans have digestive problems. Two of the top-selling drugs in America are for digestive problems, and they run in the billions. There are more than 200 over-the-counter (OTC) remedies for digestive disorders. And these can and do create additional digestive problems.

If an individual’s digestion is not working properly, the first thing is to understand what is sending the gut out-of-balance in the first place.

  • A low-fiber, high-sugar, processed, nutrient-poor, high-calorie diet causes all the wrong bacteria and yeast to grow in the gut and damages the delicate ecosystem in your intestines.
  • Overuse of medications that damage the gut or block normal digestive function, i.e., acid blockers (Prilosec, Nexium, etc.), anti-inflammatory medication (aspirin, Advil, and Aleve), antibiotics, steroids, and hormones.
  • Undetected gluten intolerance, celiac disease, or low-grade food allergies to foods such as dairy, eggs, or corn.
  • Chronic low-grade infections or gut imbalances with overgrowth of bacteria in the small intestine, yeast overgrowth, parasites.
  • Toxins like mercury and mold toxins damage the gut.
  • Lack of adequate digestive enzyme function from acid-blocking medications or zinc deficiency.
  • Stress can alter the gut’s nervous system, cause a leaky gut, and change the normal bacteria.

Visits for intestinal disorders are among the most common trips to primary care doctors. Unfortunately, most, which also includes most doctors, do not recognize or know that digestive problems wreak havoc in the entire body. This leads to allergies, arthritis, autoimmune disease, rashes, acne, chronic fatigue, mood disorders, autism, dementia, cancer, and more. Having proper gut and intestinal health is absolutely central to your health. It is connected to everything that happens in the body.


Functional Endocrinology: Hepatic Biotransformation & Hormone Balance

Functional Endocrinology: Hepatic Biotransformation & Hormone Balance

Biotransformation is the process of a substance changes from one chemical to another being transformed by a chemical reaction within the body. In the human body though, biotransformation is the process of rendering nonpolar (fat-soluble) compounds to polar (water-soluble) substances so they can be excreted in urine, feces, and sweat. It also serves as an important defense mechanism in the body to eliminate toxic xenobiotics out of the body through the liver. The liver is the one that takes these toxins and transformed them into suitable compounds to excrete out of the body as biotransformation.

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Detoxification is also known as �detoxication� in literature. It is also a type of alternative medicine treatment that aims the body to get rid of unspecified �toxins.� It is highly important for a person to detox their body and with biotransformation, it can be classified into two categories, under normal sequences, which tends to react with a xenobiotic. They are called Phase 1 and Phase 2 reactions that help the body with detoxification.

Phase 1 Reactions

Phase 1 reaction is consisting of oxidation-reduction and hydrolysis. Research shows that Phase 1 is generally the first defense employed by the body to biotransform xenobiotics, steroid hormones, and pharmaceuticals. They create CYP450 (cytochrome P450) enzymes and are described as functionalization microsomal membrane-bound that are located in the liver but can also be in enterocytes, kidney, lungs and the brain in the body. The CYP450 enzymes can be beneficial or have consequences for an individual�s response to the effect of a toxin they are exposed to.

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Studies have been shown that phase 1 reactions have been affecting the elderly population. It states that hepatic phase 1 reaction involving oxidation, hydrolysis, and reduction appears to be more altered by age since the elderly population comprises the fastest-growing segment of the world�s population. It also states that there is a predictable, age-related decline in cytochrome P-540 function and combined with the polypharmacy that much of the elderly population experiences, this may lead to a toxic reaction of medication.

Phase 2 Reaction

Phase 2 reaction is part of the cellular biotransformation machinery and is a conjugation reaction in the body. They can involve the transfer of a number of hydrophilic compounds to enhanced the metabolites, and the excretion in the bile or urine in the body. The enzymes in Phase 2 reaction can also comprise multiple proteins and subfamilies to play an essential role in eliminating the biotransformed toxins and metabolizing steroid hormones and bilirubin in the body.

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Phase 2 enzymes can function not only in the liver but also in other tissues like the small intestines. When it combined with Phase 1, they can help the body naturally detox the toxins that the body may encounter. Hormones, toxins, and drugs undergo a hepatic transformation by Phase 1 and Phase 2 pathways in the liver, then are eliminated by phase 3 pathways.

Xenobiotics

Xenobiotics has been defined as chemicals that undergo metabolism and detoxication to produce numerous metabolites, some of which have the potential to cause unintended effects such as toxicity. They can also block the action of enzymes or receptors used for endogenous metabolism and produce liver damage to a person. Xenobiotics like drugs, chemotherapy, food additives, and environmental pollutants can generate serval free radicals that lead to an increase of oxidative stress in the cells. Accumulation of oxidative stress in the body can lead to an increase in potential cellular reduction in the body.

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Research shows that the body has a major challenge when it is detoxifying xenobiotics out of the body system and the body must be able to remove the almost-limitless number of the xenobiotic compounds from the complex mixture of chemicals that are involved in normal metabolism.

Studies even show that if the body doesn�t have a normal metabolism, many xenobiotics would reach toxic concentrations. It can even reach the respiratory tract either through airborne toxins or the bloodstream. It is important to make sure that the body and especially the liver to be healthy. Since the liver is the largest internal organ, it is responsible for detoxifying the toxins out of the body as urine, bile, and sweat.

Conclusion

Biotransformation is the process of substance changes from one chemical to another. In the body, it is a process of rendering fat-soluble compounds to water-soluble compounds, so it can be excreted out of the body as either urine, feces, or sweat. The liver is the one that causes toxic xenobiotics to transform into biotransformation and going through phase 1 and 2 to excrete the toxins out of the body for a healthy function.

Phase 1 reactions in the body are the first line of defense of the body detoxifying itself. Phase 2 creates CYP450 (cytochrome P450) that helps the body take the xenobiotic toxins and oxidates to reduce and hydrolysis the toxins to metabolites. Those metabolites then transform into Phase 2 reactions, which conjugates the metabolites in the body to be excreted out of the body. There are many factors that can make the body have xenobiotics, but the liver is the main organ to detoxify the xenobiotics out of the system. If there is an abundance of xenobiotics in the body, it can cause toxicity reaction causing the body to develop chronic illnesses. These products are known to help support the intestines and liver detoxication as well as, to help support hepatic detoxication for optimal healthy body function.

October is Chiropractic Health Month. To learn more about it, check out Governor Abbott�s bill on our website to get full details.

The scope of our information is limited to chiropractic, musculoskeletal and nervous health issues as well as functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or chronic disorders of the musculoskeletal system. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .


References:

Chang, Jyh-Lurn, et al. �UGT1A1 Polymorphism Is Associated with Serum Bilirubin Concentrations in a Randomized, Controlled, Fruit and Vegetable Feeding Trial.� The Journal of Nutrition, U.S. National Library of Medicine, Apr. 2007, www.ncbi.nlm.nih.gov/pubmed/17374650/.

Croom, Edward. �Metabolism of Xenobiotics of Human Environments.� Progress in Molecular Biology and Translational Science, U.S. National Library of Medicine, 2012, www.ncbi.nlm.nih.gov/pubmed/22974737.

Hindawi, Unknown. �Xenobiotics, Oxidative Stress, and Antioxidants.� Xenobiotics, Oxidative Stress, and Antioxidants, 17 Nov. 2017, www.hindawi.com/journals/omcl/si/346976/cfp/.

Hodges, Romilly E, and Deanna M Minich. �Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application.� Journal of Nutrition and Metabolism, Hindawi Publishing Corporation, 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4488002/.

Kaye, Alan D, et al. �Pain Management in the Elderly Population: a Review.� The Ochsner Journal, The Academic Division of Ochsner Clinic Foundation, 2010, www.ncbi.nlm.nih.gov/pmc/articles/PMC3096211/.

M.Haschek, Wanda, et al. �Respiratory System.� ScienceDirect, Academic Press, 17 Dec. 2009, www.sciencedirect.com/science/article/pii/B9780123704696000064.

panelEdwardCroom, Author links open overlay, et al. �Metabolism of Xenobiotics of Human Environments.� ScienceDirect, Academic Press, 11 Sept. 2012, www.sciencedirect.com/science/article/pii/B9780124158139000039.

Sodano, Wayne, and Ron Grisanti. �The Physiology and Biochemistry of Biotransformation/Detoxification.� Functional Medicine University, 2010.

Unknown, Unknown. �ToxTutor – Introduction to Biotransformation.� U.S. National Library of Medicine, National Institutes of Health, 2017, toxtutor.nlm.nih.gov/12-001.html.

Zhang, Yuesheng. �Phase II Enzymes.� SpringerLink, Springer, Berlin, Heidelberg, 1 Jan. 1970, link.springer.com/referenceworkentry/10.1007%2F978-3-642-16483-5_4510.

 

 

The Gut-Brain Connection

The Gut-Brain Connection

The gut-brain connection is essential in the body. If an individual has a leaky gut that is causing inflammation, it can send the signal to the brain and it can create problems like neurotransmitter dysfunction to systems that just don�t connect. The leaky gut can lead to brain dysfunction or brain dysfunction can lead to leaky gut. Sometimes an autoimmunity disease in the stomach can lead to a disruption in the mind. Then, brain disruption can also lead to inflammation in the gut. It�s a never-ending loop that the brain and gut can go on forever. Studies have stated that gut microbiota appears to influence the development of emotional behaviors like stress, pain modulation systems, and brain neurotransmitter systems.

The Brain System to the Gut System

The brain is the main control room that controls the body�s system and how the body should behave. The human brain also contains neuron cells that are found in the central nervous system. With the gut-brain connection, two critical systems help send the signal to the brain and the gut; these are known as the vagus nerve and the neurotransmitters.

The Vagus Nerve

There are approximately 100 billion neurons in the brain, while the gut contains about 500 million neurons, which is connected to the brain through the nerves in the nervous system. The vagus nerve is one of the most significant nerves that send signals back and forth to the brain and the gut. When the body is stressed, the stress signal inhibits the vagus nerve, and it can cause problems to the gut-brain connection. Animal studies have shown that any stress that is in the animal�s body can cause gastrointestinal issues and PTSD. While another study stated that individuals that have IBS (irritable bowel syndrome) have a reduced function of the vagus nerve.

There are ways to reduce the stress hormone so that the vagus nerve can function properly and send the right signals to the gut and the brain. Probiotic foods can help lower the amount of stress hormone in the bloodstream. When that happens, the body can start healing naturally when the stress is reduced; however, if the vagus nerve is damaged, then the probiotic has no effect.

Neurotransmitters

Neurotransmitters are produced chemically in the brain by controlling feelings and emotions in the body. Since the brain and gut are connected to neurotransmitters, the neurotransmitters can create these compounds that help contribute to the body. In the brain, the neurotransmitter can produce serotonin to make the person feel happy and help control their body�s biological clock.

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In the gut, there are trillions of microbes that live there, and interestingly researchers stated that serotonin is mainly being produced by the gut system. Another neurotransmitter that is provided in the gut is called GABA (gamma-aminobutyric acid), which helps control the feeling of fear and anxiety. When the brain feels overly anxious or has been through a traumatic experience that has caused them to be fearful, it can cause them to be hypersensitive and can cause a chemical imbalance to the gut, causing inflammation or leaky gut if it is severe.

The Gut System to the Brain System

The gut microbes can produce neurotransmitters to send to the brain, protect the intestinal barrier and the tight junction integrity, regulate the mucosal immune system, and modulates the enteric sensory afferents. The gut microbe produces a lot of SCFA (short-chain fatty acids) that form a barrier between the brain and blood flow called the blood-brain barrier. The blood-brain barrier protects the CNS (central nervous system) from toxins, pathogens, inflammation, injury, and disease.

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The gut microbes also metabolize bile and amino acids to help produce other chemicals that affect the brain. When the body is stressed, it can reduce the production of bile acid by gut bacteria and alter the genes that are involved. When that stress is still creating problems in mind, the gut can develop gastrointestinal issues that will destroy the permeability barrier that is protecting the intestines.

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The gut-brain connection plays an essential role in the body�s immune system as it controls inflammation and what passes into the body. Since the immune system controls inflammation, if it is turned on for too long, inflammation can occur as well as several brain disorders like depression and Alzheimer�s disease. Stress can even disrupt the gut by causing contractions to the GI tract, make inflammation worse in the intestinal permeability, and making the body more at risk to infections.

When the body starts to alleviate stress, it can naturally heal itself, and the gut-brain connection can begin functioning normally. With changes in a person�s eating habits and lifestyle, it can drastically change a person�s mood and recover from intestinal ailments they may have. If the brain feels right, then the gut feels good as well. They work together side by side to make sure that the body is functioning correctly. When either one is being disrupted, then the body does not function properly.

Conclusion

Therefore, the gut-brain connection is vital to the body. Neurotransmitters and other components that are in both systems work together to make sure that the body is working correctly. When one of the connections is being disrupted, however, the body can develop many chronic illnesses even if the person seems fine. By altering little things like changing a person�s diet and lifestyle, it can help improve the body and bring the balance back to the gut-brain connection.

In honor of Governor Abbott’s proclamation, October is Chiropractic Health Month. To learn more about the proposal on our website.

The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues as well as functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or chronic disorders of the musculoskeletal system. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .


References:

Anguelova, M, et al. �A Systematic Review of Association Studies Investigating Genes Coding for Serotonin Receptors and the Serotonin Transporter: I. Affective Disorders.� Molecular Psychiatry, U.S. National Library of Medicine, June 2003, www.ncbi.nlm.nih.gov/pubmed/12851635.

Bravo, Javier A, et al. �Ingestion of Lactobacillus Strain Regulates Emotional Behavior and Central GABA Receptor Expression in a Mouse via the Vagus Nerve.� Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 20 Sept. 2011, www.ncbi.nlm.nih.gov/pubmed/21876150.

Carabotti, Marilia, et al. �The Gut-Brain Axis: Interactions between Enteric Microbiota, Central and Enteric Nervous Systems.� Annals of Gastroenterology, Hellenic Society of Gastroenterology, 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4367209/.

Daneman, Richard, and Alexandre Prat. �The Blood-Brain Barrier.� Cold Spring Harbor Perspectives in Biology, Cold Spring Harbor Laboratory Press, 5 Jan. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4292164/.

Herculano-Houzel, Suzana. �The Human Brain in Numbers: a Linearly Scaled-up Primate Brain.� Frontiers in Human Neuroscience, Frontiers Research Foundation, 9 Nov. 2009, www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/.

Lucas, Sian-Marie, et al. �The Role of Inflammation in CNS Injury and Disease.� British Journal of Pharmacology, Nature Publishing Group, Jan. 2006, www.ncbi.nlm.nih.gov/pmc/articles/PMC1760754/.

Mayer, Emeran A, et al. �Gut/Brain Axis and the Microbiota.� The Journal of Clinical Investigation, American Society for Clinical Investigation, 2 Mar. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4362231/.

Mayer, Emeran A. �Gut Feelings: the Emerging Biology of Gut-Brain Communication.� Nature Reviews. Neuroscience, U.S. National Library of Medicine, 13 July 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3845678/.

Mazzoli, Roberto, and Enrica Pessione. �The Neuro-Endocrinological Role of Microbial Glutamate and GABA Signaling.� Frontiers in Microbiology, Frontiers Media S.A., 30 Nov. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC5127831/.

Pellissier, Sonia, et al. �Relationship between Vagal Tone, Cortisol, TNF-Alpha, Epinephrine and Negative Affects in Crohn’s Disease and Irritable Bowel Syndrome.� PloS One, Public Library of Science, 10 Sept. 2014, www.ncbi.nlm.nih.gov/pubmed/25207649.

Rooks, Michelle G, and Wendy S Garrett. �Gut Microbiota, Metabolites and Host Immunity.� Nature Reviews. Immunology, U.S. National Library of Medicine, 27 May 2016, www.ncbi.nlm.nih.gov/pubmed/27231050.

Sahar, T, et al. �Vagal Modulation of Responses to Mental Challenge in Posttraumatic Stress Disorder.� Biological Psychiatry, U.S. National Library of Medicine, 1 Apr. 2001, www.ncbi.nlm.nih.gov/pubmed/11297721.

Yano, Jessica M, et al. �Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis.� Cell, U.S. National Library of Medicine, 9 Apr. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4393509/.

What To Do With SIBO El Paso, Texas

What To Do With SIBO El Paso, Texas

SIBO (small intestinal bacterial overgrowth) is defined as 105 up to 106 organisms of bacteria in the small intestines. It is highly relevant to remember that the abundance of bacteria in the small intestine that has SIBO, are healthy bacteria that live in the gastrointestinal tract. It means that the bacteria in the digestive tract is either missed or dislocated and is in the wrong place in the small intestines. While SIBO still remains a poorly understood disease, it is frequently implicated to be the cause of chronic diarrhea and malabsorption. Individuals who have SIBO can also suffer from many chronic illnesses. This includes unintended weight loss, nutritional deficiencies, and osteoporosis.

SIBO and IBS

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Studies have indicated that 84% of individuals that has IBS (irritable bowel syndrome) will have SIBO. SIBO is one of the causes of leaky gut, and leaky gut is one of the triad factors that can lead the body to have an autoimmune disease. Health care professionals that diagnose individuals who have SIBO can link the virus to other health problems that the individual may have. Studies have mentioned that when LPS (lipopolysaccharide) is moving from the large intestines to the small intestines, it can contribute to developing intestinal inflammation. With LPS, it can cause an increase of intestinal tight junction permeability or leaky gut.

So SIBO will release LPS into the gut, causing the leaky gut to the gut system in the body. Another study showed that autoimmune diseases are always a triad of a few different things. To have an autoimmune disease, you have to have the gene to get the disease. Although most people know that if they have a gene, doesn�t mean that they will have an autoimmune disease. Even if they don�t have an autoimmune disease, there�s an environmental trigger that will come on and creates an epigenetic change. This will cause the gene in the human body to be expressed.

Irritable_bowel_syndrome

So the first two factors of the autoimmune disease, are a genetic factor and an environmental factor, the third and final factor is intestinal permeability. So if the primary two factors that are causing disruption to the intestinal permeability, they will prevent the intestinal permeability to actually heal itself. With all three elements being linked to autoimmune disease and SIBO, it will cause the body to have the leaky gut syndrome and health problems to individuals.

So when doctors are diagnosing the patient that has SIBO, they will do a lactulose breath test. What this test does, is that it will indicate that the patient has IBS bloating, and it is causing them discomfort in their gut. Research stated that the lactulose breath test shows the correlation between the pattern of the bowel movements and the type of excreted gas in the stomach. So for anyone that is positive with IBS and takes the breath test, they will understand the consequences of the factors that are leading to the SIBO disease and causing leaky gut.

How do we get SIBO?

With the understanding of what SIBO is, we can see that SIBO is not the only cause of irritable bowel syndrome, but the big player of the syndrome. So taking a step back, we have to discuss what the MMG (Migrating Motor Complex) is before we go further in explaining the pathogenesis of the SIBO disease. Migrating motor complexes are waves of electrical activity that is sweeping through the intestines in a regular cycle. It often happens when a person is fasting, therefore with MMG, we can look at the acute gastroenteritis in the body.

With acute gastroenteritis, the body has some sort of severe infection like bloating, diarrhea, constipation, or a variety of things that are infectious to the gut; however, they are self-limiting. Healthcare professionals who see patients with these acute infections can see that most of the bacteria can cause gastroenteritis, pile up, and release CTD (cytolethal distending toxin). What CTD does is that it will create a reaction against vinculin; which regulates the ICC (interstitial cells of Cajal) and the ICC then regulates the migrating motor complex.

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So when the CTD releases toxins in the gut, it causes a reaction to a molecular mimicry reaction. That reaction causes the body to create antibodies to fight against that toxin but through molecular mimicry. CTD looks exactly like vinculin and cross-reacts with the antibodies, So now those antibodies are attacking vinculin, thus damaging the ICC. Since the MMC clears the intestinal tract, when a person is fasting, and the CTD is damaging the intestines, SIBO is created since the body can not flush out the bacteria.

Studies have shown that there are many ways to get SIBO, it can happen by either food poisoning, abdominal surgery, or low stomach acid. Another thing to mention is that mostly 70% of SIBO is caused by food poisoning. Most people who had to suffer from food poisoning don�t realize that SIBO is already in their gut. So the research states that small bowel motility disorders can be the predispose development of SIBO since the bacteria may not be effectively swept from the bowel into to colon.

Treating SIBO

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There are many ways to treat SIBO, healthcare professionals can suggest these treatments to their patients who have SIBO and start restoring their intestinal barrier in the long haul. So here are some of the procedures that can help the body and treat SIBO.

  • Pharmaceuticals: If a patient has constipation and is taking rifaximin if the symptoms are not clearing up, adding another medication with rifaximin for 14 days may help in battling SIBO. It will take a bit longer, but it will help clear the SIBO out of the gut.
  • Herbal Treatment: With herbal treatments, there are many ways to help treat SIBO naturally. It can be berberine containing herbs, oil of oregano, neem, garlic, Lactobacillus plantarum, Lauricidin, and Antrantil. These herbal treatments can naturally help to fight against SIBO, and studies show that 46% of patients feel a lot better in a short amount of time.

Conclusion

So SIBO is a bacterial disease that can disrupt the gastrointestinal tract and cause the leaky gut to the body. It will cause inflammation and can be in an individual�s body through three factors like genetics, environmental triggers, and food poisoning. It can be treated through pharmaceuticals and herbal treatments prescribed by doctors.� In honor of Governor Abbott’s proclamation, October is Chiropractic Health Month, learn more about this proposal on our website and read what the proposal is all about. The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues as well as functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or chronic disorders of the musculoskeletal system. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .


References:

Bezine, Elisabeth, et al. �The Cytolethal Distending Toxin Effects on Mammalian Cells: a DNA Damage Perspective.� Cells, MDPI, 11 June 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4092857/.

Brown, Kenneth, et al. �Response of Irritable Bowel Syndrome with Constipation Patients Administered a Combined Quebracho/Conker Tree/M. Balsamea Willd Extract.� World Journal of Gastrointestinal Pharmacology and Therapeutics, Baishideng Publishing Group Inc, 6 Aug. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4986399/.

Chedid, Victor, et al. �Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth.� Global Advances in Health and Medicine, Global Advances in Health and Medicine, May 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4030608/.

Dukowicz, Andrew C, et al. �Small Intestinal Bacterial Overgrowth: a Comprehensive Review.� Gastroenterology & Hepatology, Millennium Medical Publishing, Feb. 2007, www.ncbi.nlm.nih.gov/pmc/articles/PMC3099351/.

Endo, EH, and Dias Filho. �Antibacterial Activity of Berberine against Methicillin-Resistant Staphylococcus Aureus Planktonic and Biofilm Cells.� Austin Journal of Tropical Medicine & Hygiene, 19 Feb. 2015, austinpublishinggroup.com/tropical-medicine/fulltext/ajtmh-v1-id1005.php.

Fasano, Alessio, and Terez Shea-Donohue. �Mechanisms of Disease: the Role of Intestinal Barrier Function in the Pathogenesis of Gastrointestinal Autoimmune Diseases.� Nature News, Nature Publishing Group, 1 Sept. 2005, www.nature.com/articles/ncpgasthep0259.

Ghonmode, Wasudeo Namdeo, et al. �Comparison of the Antibacterial Efficiency of Neem Leaf Extracts, Grape Seed Extracts and 3% Sodium Hypochlorite against E. Feacalis – An in Vitro Study.� Journal of International Oral Health: JIOH, International Society of Preventive and Community Dentistry, Dec. 2013, www.ncbi.nlm.nih.gov/pubmed/24453446.

Guo, Shuhong, et al. �Lipopolysaccharide Regulation of Intestinal Tight Junction Permeability Is Mediated by TLR4 Signal Transduction Pathway Activation of FAK and MyD88.� Journal of Immunology (Baltimore, Md. : 1950), U.S. National Library of Medicine, 15 Nov. 2015, www.ncbi.nlm.nih.gov/pubmed/26466961.

Lin, Henry C. �Small Intestinal Bacterial Overgrowth: a Framework for Understanding Irritable Bowel Syndrome.� JAMA, U.S. National Library of Medicine, 18 Aug. 2004, www.ncbi.nlm.nih.gov/pubmed/15316000.

Preuss, Harry G, et al. �Minimum Inhibitory Concentrations of Herbal Essential Oils and Monolaurin for Gram-Positive and Gram-Negative Bacteria.� Molecular and Cellular Biochemistry, U.S. National Library of Medicine, Apr. 2005, www.ncbi.nlm.nih.gov/pubmed/16010969.

Sienkiewicz, Monika, et al. �The Antibacterial Activity of Oregano Essential Oil (Origanum Heracleoticum L.) against Clinical Strains of Escherichia Coli and Pseudomonas Aeruginosa.� Medycyna Doswiadczalna i Mikrobiologia, U.S. National Library of Medicine, 2012, www.ncbi.nlm.nih.gov/pubmed/23484421.

Soifer, Luis Oscar, et al. �Comparative Clinical Efficacy of a Probiotic vs. an Antibiotic in the Treatment of Patients with Intestinal Bacterial Overgrowth and Chronic Abdominal Functional Distension: a Pilot Study.� Acta Gastroenterologica Latinoamericana, U.S. National Library of Medicine, Dec. 2010, www.ncbi.nlm.nih.gov/pubmed/21381407/.

How To Deal With Mycotoxin El Paso, Texas

How To Deal With Mycotoxin El Paso, Texas

For anyone that has dealt with mold knows that it is mostly found in fresh produce when it hasn’t been eaten. It is even there is a new damp spot in the house, and it�s left untreated. Mold is a type of fungus that is presented everywhere, including the air. It can actually cause someone highly sensitive to mold exposure to have chronic raspatory illnesses like asthma and bronchitis.

Studies show that the most common species of mold is Stachybotrys chartarum or black mold. This type of fungus thrives in warm, moist environments, including the basement, the bathroom, and the kitchen. It releases toxins in the air that is irritating or harmful to individuals with existing health conditions and becoming mycotoxin.

What is Mycotoxin?

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A mycotoxin is a secondary metabolite being produced by organisms of the fungal kingdom. It can move in and out of cells in the body, causing inflammation when it is indigested. Researchers suggest that mycotoxin can link to serious health problems to people who live in contaminated buildings, and it can have long-term results. In most cases, mycotoxin can cause problems in the gut by consuming moldy food; causing leaky gut and destroying the gut microflora.

Here are some of the symptoms of mycotoxin:

  • Aches and pains
  • Mood changes
  • Headaches
  • Brain fog
  • Asthma
  • Watery, red eyes
  • Runny or blocked nose
  • Gut inflammation
  • Sore throat

They are teratogenic, mutagenic, nephrotoxic, immunosuppressive, and carcinogenic. They can cause DNA damage, cancer, immune suppression, neurological issues, and a variety of adverse health effects on the human body. With mycotoxins, they have spores and pieces of hyphae that releases toxins into the air. They are tiny, but they are not easily detectable in the bloodstream since they can attach themselves to enzymes that are involved in insulin receptors. This results in dysfunction the in cells ability to intake and process glucose in the gut.

When mycotoxin is in the gut, it damages the intestinal barrier. It can cause malabsorption of food and disrupts the protein synthesis. When that happens, the individual�s autoimmunity will rise up, causing their bodies to go into overdrive to fight the problem.

Mycotoxin can actually grow in grains such as rice. The fungal mycotoxin has been known to cause liver damage since the contaminated food is being consumed by people, and it creates a rise in inflammation. When this happens, individuals start being sensitive to the contaminated foods that they are consuming. There is still more research to mycotoxin that is being produced to create a resistance to mycotoxin exposure.

Diagnosing Mycotoxin

Mycotoxin can�t be diagnosed by the symptoms themselves, doctors can perform one of these tests to determine the severity of mycotoxins in individuals.

  • Blood test: Physicians can take a patient�s blood sample and send it to a testing lab to test. This is to see if there is a reaction of specific antibodies in the patient�s immune system. A blood test can even check the individual�s biotoxins in their blood to see if mycotoxin present.
  • Skin prick test: Healthcare professionals can take tiny amounts of mold and use a small needle to apply it onto the patient�s skin. This is to determine if the individual is breaking out in bumps, a rash or hives, then they are allergic to any mold species.

Diagnosing mycotoxin is known by many names, but it is mostly called mast cell disorder. Even though they are different and have different manifestations, diagnosing them in the body is essential to help individuals to heal their ailments. With technology getting better, healthcare physicians can detect mycotoxins in the body much faster.

Treating Mycotoxin

There are many ways to treat mycotoxin. Options include:

  • Avoiding the mold whenever possible.
  • A nasal rinse to flush out the mold spores that are in the nose.
  • Antihistamines to stop the itchiness, runny noses, and sneezing due to mold exposure.
  • A short term remedy for congestion is using decongestant nasal spray.
  • Montelukast is an oral medication to reduce the mucus in a patent�s airways to lower the symptoms for both mold allergies and asthma.
  • Doctors can recommend patients an allergy shot to build up the patient�s immunity to mycotoxin if the exposure is long term.

How to check for mycotoxin?

When individuals are checking for mycotoxins in their environment, it is best to hire professionals to help identify and remove it. A lot of individuals can look for black clusters growing in warm, moist rooms and can search for the causes of mold growth like any leaks, old food, papers, or wood. People can throw away the items that are affected by mold or that are contributing to mold growth. They can also remove the things that are not affected by mold exposure.

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Wearing a mold-resistant suit, mask, gloves, and boots can protect individuals as they are getting rid of mildew and mold from their environment. Even purchasing a HEPA air purifier can help get rid of the spores to ensure that no allergens will affect the body�s immune system. When individuals are removing the mold exposure out of the affected area, they can cover the non-affected surfaces with bleach or a fungicidal agent. Then let it dry to prevent the mold from reproducing on the same area it has infected.

Conclusion

Since researchers are still doing a test on mycotoxin, mold exposure is still all around the world and in many forms. It can even contaminate food and places where it can thrive and grow. Individuals can prevent it from locating the source and can take precautions when they are exposed to the spores. If the individual is exposed to mycotoxin, going to the doctors to get tested is the best route to go. The scope of our information is limited to chiropractic, musculoskeletal, and nervous health issues as well as functional medicine articles, topics, and discussions. We use functional health protocols to treat injuries or chronic disorders of the musculoskeletal system. To further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 .


References

Borchers, Andrea T, et al. �Mold and Human Health: a Reality Check.� Clinical Reviews in Allergy & Immunology, U.S. National Library of Medicine, June 2017, www.ncbi.nlm.nih.gov/pubmed/28299723.

Do�en, Ina, et al. �Stachybotrys Mycotoxins: from Culture Extracts to Dust Samples.� Analytical and Bioanalytical Chemistry, Springer Berlin Heidelberg, Aug. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4939167/.

Gautier, C, et al. �Non-Allergenic Impact of Indoor Mold Exposure.� Revue Des Maladies Respiratoires, U.S. National Library of Medicine, June 2018, www.ncbi.nlm.nih.gov/pubmed/29983225.

Hurra�, Julia, et al. �Medical Diagnostics for Indoor Mold Exposure.� International Journal of Hygiene and Environmental Health, U.S. National Library of Medicine, Apr. 2017, www.ncbi.nlm.nih.gov/pubmed/27986496.

Jewell, Tim. �Black Mold Spores and More.� Black Mold Exposure, 1 June, 2018, www.healthline.com/health/black-mold-exposure.

Leonard, Jayne. �Black Mold Exposure: Symptoms, Treatment, and Prevention.� Medical News Today, MediLexicon International, 17 Sept. 2019, www.medicalnewstoday.com/articles/323419.php.

Pitt, John I, and J David Miller. �A Concise History of Mycotoxin Research.� Journal of Agricultural and Food Chemistry, U.S. National Library of Medicine, 23 Aug. 2017, www.ncbi.nlm.nih.gov/pubmed/27960261.

Sun, Xiang Dong, et al. �Mycotoxin Contamination of Rice in China.� Journal of Food Science, U.S. National Library of Medicine, Mar. 2017, www.ncbi.nlm.nih.gov/pubmed/28135406.

 

 

 

Intestinal Permeability and Functional Integrated Medicine Part: 2 El Paso, Texas

Intestinal Permeability and Functional Integrated Medicine Part: 2 El Paso, Texas

Today, we will be talking about what does the protein compounds and the peptide compounds do when a patient is being tested for food sensitivity. And we will also discuss what the Lectin and Dairy Zoomer do when a patient has a reaction to those types of food groups. In the last article, we mentioned about immunoglobulins in the intestinal barrier. And what do IgA and IgG antibodies do to the peptide and protein level?

Proteins vs. Peptides

So let us take a look at proteins and peptides since this is what Vibrant Food Zoomers are actually testing on a patient. Remember that the Food Zoomers are testing the peptides in the whole protein and testing all the links to see what the patient is actually sensitive to the foods they are consuming.

Proteins

Protein is basically abundant biomolecule that is consist of one or more long chains of amino acid residues. Proteins can be found in whole foods like meats and vegetables that can help the muscles in our bodies. In the last article, we talked about how IgA and IgG antibodies are used for food sensitivity testing.

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However, there is a limitation of a whole protein food sensitivity testing on a patient. Practitioners do make the assumption that the patient�s gut barrier is functional and intact since there are no signs of a leaky gut syndrome presented in the results. But, if that patient has the leaky gut syndrome, then the food sensitivity test will reflect what the patient has been eating. Another assumption is that the patient�s HCI and digestive enzymes are sufficient for tolerable proteolysis. Which means that those enzymes are breaking down whole proteins into smaller peptides.

Peptides

Peptides are what in protein molecules as they are short chains of amino acids and are linked by the peptide bonds. When they are being tested by the food sensitivity tests, the reproducibility is higher. It doesn�t rely on the excess HCI (hydrochloric acid) or enzymes. What the test eliminates is the cross-reactivity because peptides in proteins are not going to have molecular mimicry to other unrelated proteins.

The antibodies are highly specific to the peptides because they are not going to be generalized or more massive antibodies of proteins since cross-reactivity is eliminated. Another thing is that the peptide test does is that it can measure thousands of peptides in one protein for a full spectrum of reactivity.

Peptide-Bond-Formation

When patients are coming in with digestive problems and inflammatory condition/symptoms, practitioners take note that a lot of patients commonly have hypochlorhydria and deficiencies of enzymes and/or bile acids. Most patients sometimes have moderate to severe impairment of the intestinal barrier. When that happens, local doctors discuss with them that they may have to change their diets slowly but surely. And with integrative functional medicine that can occur.� Local practitioners look at their patient�s ailments and start detoxifying their bodies slowly. This helps their bodies heal and recommend them whole, nutritious, organic foods, and supplements to help repair the body naturally. Sometimes medicines can cause disruption to our bodies, however with whole natural foods and specific diets, it can help restore our bodies. Plus making sure that we exercise to make our bodies feel good and look good.

So now that we understand what proteins and peptides do when they are being tested. Let�s take a look at the food zoomers that can help you in case you have a sensitivity to these food groups. These are the Vibrant Lectin Zoomer and the Dairy Zoomer.

Lectin Zoomer

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The Lectin Zoomer is consist of a handful of lectins and a handful of aquaporins. The most common lectins that people consume are barley, bell pepper, chickpea, corn, cucumber, potato, etc. And the most common aquaporins that people consume are spinach, soybean, tomato, tobacco, etc.

Difference between Lectins and Aquaporins

The difference between lectins and aquaporins is that lectins are sugar-binding proteins that are found in both animals and plants, which can bind to the carbohydrate structures on cells. While aquaporins are water channels that are found in cavities in both plants and humans. Some aquaporins can cross-react and can lead to primarily neurological symptoms.

How Problematic are Lectins?

Some studies show cell toxicity in humans is done by using extreme cytotoxic lectins. Ricin, for example, is a common biological warfare element that is not from the commonly consumed legumes or grains. It contains cytotoxic lectins and is being consumed by animals like mice or pigs. The assumption is being made that there are similarities with humans and animal gut glycosylation (the process of sugar-binding) in these situations.

Unfortunately, though it hasn�t been demonstrated thoroughly. But lectins have biological activity in the human body. They have been used as a cancer treatment mechanism because they can agglutinate cancer cells. Which means that they produce cytotoxicity to cancer cells and can actually carry chemotherapy across cancer cell membranes.

Even though that is a good thing, lectins can facilitate the bacterial endotoxins across the epithelial barrier and go into the peripheral tissues. And that can cause inflammation to the intestinal epithelial barrier in the small intestines. Animals studies show that raw lectin consumptions can cause hemagglutinating effects, causing inflammation.

But we as humans don�t eat raw lectins because they are cooked, not pressurized cook. Certain foods that are lectins can be eaten raw or cooked. But animal studies stated that they are using for these studies are grain and legume lectins that are raw like beans and grains. But the upside is that lectins can affect the metabolism of nutrients to increase fat loss which is a positive side effect.

Measuring the Sensitivity to Lectins

On the Food Zoomers test, lectins are really not included in each analysis, except for the Wheat Zoomer. Surprisingly, a Food Zoomer may be non-reactive, but whoever is sensitive to a lectin component in the food they eat, may be reactive. So when that happens, it is necessary to eliminate the food temporarily.

If you are sensitive to a particular food, you can have a Food Zoomer and a lectin Zoomer combine. Because if you are sensitive to the food you consume, and it doesn�t show up on the Food Zoomer, but it shows up on the Lectin Zoomer. Then you should eliminate it from your diet for a bit until you retake the test.

Conditions Associated with Lectins

If you do have a lectin sensitivity, here are some of the terms that can affect your body.

  • Arthritis/rheumatoid arthritis
  • Connective tissue disorder
  • Gastrointestinal inflammation
  • Intestinal permeability
  • Possible cancer in established cancer patients

Now let�s take a look at the Dairy Zoomer and its functions if you are sensitive to whole dairy products.

Dairy Zoomer

The Dairy Zoomer is a peptide level assessment of the full spectrum of immune response possible to proteins in cow�s milk dairy. What this means that the Dairy Zoomer is only specific to cow�s milk. Since some proteins in cow�s milk are similar enough in the molecular structure to have the same homology to goat or sheep�s milk.

This means that these other kinds of milk may be potential can cause inflammatory in some individuals. The oral challenge for alternative types of fluid may be warranted, but use your best clinical judgment after the intestinal barrier is healed.

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What the Dairy Zoomer does is that it takes the milk protein and breaking each individual protein down to its different peptides. If you are wondering if the Dairy Zoomer is a test for lactose intolerance, it is not. Since lactose intolerance is not an immune-based reaction to dairy and does not involve any protein constituents of the food, therefore no antibodies are being generated.

What it is going to test for is the casein and whey proteins in the milk product from all animals, and the ratio of these proteins will vary by species. But all the proteins and milk will generally fall into one of these two proteins.

What to do with the results?

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Once your patient comes back after taking the Food Zoomers test, here are some of the things to look for when you are retesting them.

  • If there are any IgA antibodies still in your patient, warrant an immediate elimination, regardless that it�s moderate or positive.
  • If there are any Moderate IgG antibodies in your patient, then it should be eliminated in the short term. Then rotate after a 30-60-day elimination and assessing the status of the intestinal permeability to confirm that that gut barrier is no longer �leaky.�
  • If there is a positive IgG result, then it should be eliminated long term and only reintroduced after 90+ days and confirm of an intact intestinal barrier.

Conclusion

So all in all, food sensitivity combine with the food zoomers test are an excellent way to help your body, especially the intestinal system. The Food Zoomers we used is functional for our patient�s wellness. Because we want to get rid of the excess antibodies and heal our patient�s body through the use of functional medicine.

 

Intestinal Permeability and Functional Integrated Medicine Part: 2 El Paso, Texas

Intestinal Permeability and Functional Integrated Medicine Part: 1 El Paso, Texas

The usage of integrated functional medicine is essential when it comes to our bodies overall health. Local practitioners and health coaches, talk with patients on what seems to bother them. Sometimes it is a simple adjustment, but mostly it�s what�s causing them problems on the inside. Some patients have inflammation around their intestinal epithelial barriers, and it can cause a leaky gut.

In the previous article, we talked about what the microbiomes do in our intestines and what is their functions are in the intestinal epithelial barrier. However, today we will discuss what the immunoglobulins antibodies do with proteins and peptides in the intestinal permeability. As well as explaining what the Lectin Zoomer and the Dairy Zoomer does when a patient has a food sensitivity and needs testing in a two-part series about the intestinal permeability and food zoomers.

Immunoglobulins

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The first thing that we need to know is that immunoglobulins are immune-mediated reactions. So anything that involves the immune system will cause a hypersensitivity reaction to one or more food or foreign proteins, and their presence can be of one or more types of immunoglobulins.

There are 3 terms of hypersensitivities that can be involved with immunoglobulins:

  1. Allergies are the ones that are most common and are associated with anaphylaxis. Patients can have a very severe and acute immediate reaction to specific allergens like food or environmental like pollen or a bee sting.
  2. Non-allergies, sensitivity reactions involved either chemical mediators or antibody reactions.
  3. Food intolerances are non-immune-mediated reactions, and a good example is Lactose Intolerance or a bile salt deficiency. These can make somebody who has a food intolerance, can�t digest fat.

These three terms are often mistaken and used interchangeably clinically, but they are entirely different since they are not interchangeable. Especially when it comes to sensitivities and intolerances because those two commonly get used in place of each other, but they are totally different.

If you are testing your patient�s immunoglobulins, remember that antibodies are particular to each type of foreign substances and can be in three types of hypersensitivity. Antibodies will only bind an react to the specific proteins of the foreign material but not to the substance�s extract. The most common ones are type 3, where it involves IgG, IgA, and IgM. This type can tell us what cells and mechanisms are involved.

Type 3 Hypersensitivity Mechanisms

Here are the types of mechanisms that are involved with Type 3 immunoglobulins.

  • Antigens are a foreign protein that is present and is recognized as a threat or non-self.
  • Antibodies will bind to the antigen to neutralize or keep it from linking to anywhere else in the body. This is where the immune complex is formed.
  • Immune complexes insert themselves into the small blood vessel, joints, tissues, and glomeruli, causing symptoms to the body.
  • They are far more capable of interacting with complement proteins to form medium-sized complexes; which has an excess amount of antigens that are high pathogenic.
  • However, once the immune complex is in the tissue, it can induce an inflammatory response and cause damage to the body. This damage is the result of the action of cleaved complement anaphylatoxins, which can mediate a mast cell degranulation.
  • With the recruitment of inflammatory cells in the tissue, it can lead to tissue damage through phagocytosis.

IgA and IgG

In a previous article, we mentioned the mechanics of the intestinal permeability. However, we going to discuss what IgA antibodies and IgG antibodies do to the gut and to the entire body.

IgA Antibodies

IgA antibodies are found in the body where there is a mucosal lining around the areas like the nose, breathing passages, digestive tract, ears, eyes, and vaginal region. These surfaces are exposed to the outside of the environment either by air, food, or other foreign substances regularly.

IgA antibodies actually protect the body surfaces that are exposed to outside foreign substances, and these antibodies can be found in saliva, tears, and blood.

Immunoglobulin-A-IgA-Figure-1

In the gut, however, it can bind to the mucosal layer on the top of the intestinal epithelial cells to form a barrier to neutralizing threats before they reach the cell. And that is very important, especially since IgA is like an insurance policy for your gut.

IgA antibodies are considered as non-inflammatory. Which means that they don�t stimulate inflammatory processes in the body like IgG does. They do, however, create a mucosal response to a foreign antigen, and it is usually microbial (ex., bacteria, yeast, viruses, parasites) or microbial toxins. They can also generate a response to pollutants, toxins, and recognized undigested food as a foreign protein.

In the intestinal lumen, IgA can be indicative of an immune response stimulated by T-b cell interaction. So a healing intervention, if a patient has an abundance of IgA antibodies may need to target TH1 and TH2 balance so it can regulate T-reg production.

IgG Antibodies

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IgG antibodies are found in all body fluids. They happen to be the smallest but the most common of all antibodies as they make-ups about 75% to 80% of antibodies found throughout the entire body. These antibodies are essential as they fight against bacterial and viral infections, and they are the only type that can cross the placenta.

They do indicate exposure to a specific antigen, but they don�t always necessarily indicate active inflammation; however, they can contribute to it in a dose-independent.

Why measure IgA and IgG?

So why do we measure IgA and IgG? Surprisingly some people don�t produce as much or any IgA antibodies, and therefore, local practitioners would not know if their patients have formed a reactivity to an antigen if they don�t check their IgG levels.

Surprisingly, some IgG antibodies are not an indicator of actual inflammation or disease process. Some IgG antibodies are formed in response to a protein as sort of a tracker in the body but do not elicit a reaction. However, IgA antibody is coupled with IgG to indicate a bit stronger immune response to an antigen in some cases.

IgA and IgG in the Protein Level

IgA and IgG testing in the protein level is what the food sensitivity tests are looking at. They look for the whole protein, which is the extract level. All food sensitivity test looks for residues of carbohydrate and lipid-based particles. It�s not pure protein but that what the test does, it seems for the reactive compound. Some of the strengths are that the test gives an acute measure of IgG and IgA to a specific protein. It can also be suitable for associating Type 3 reactions involving IgG and IgA complexes, and if the IgG is pathogenic, then it will be beneficial.

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Some of the weaknesses are that IgG can be a protective antibody, and it may be a good thing. It means that the immune system is handling it and there�s nothing necessarily wrong about that. IgG and IgA antibodies represent whole proteins being presented to the immune system can it also be an indicator that a patient may have a lack of sufficient digestive capacity when many food sensitivities are being detected.

IgG and IgA in the Peptide Level

When IgG and IgA are being tested at the peptide level, this is where the food zoomer test focuses on. This is because there is a high level of antibodies specificity, cross-reactivity is minimized if not completely eliminated. The concept of foods that are cross-react, for example, gluten, might cross-react to other foods that are similarly shaped in their molecular structure, then you should eliminate the gluten out of your diet as well as the foods that are in contact with them.

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However, if the antibodies to gluten are being picked up at the peptide level, then it won�t look at those foods that are being cross-reactive to gluten. The antibodies will only bind to the individual peptides than the whole protein. This will be a more accurate assessment of whether or not that the patient is sensitive to the foods their body is reacting to.

What is Loss of Oral Tolerance?

Loss of oral tolerance is a term used to describe the phenomenon of someone developing a sensitivity, whether it is accompanied by symptoms or not, and it�s usually a commonly consumed or semi-regularly consumed food. When that happens, there is a production of inflammatory cytokines and antibodies that will respond to the continued exposure to the food.

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For the inflammatory responses to be eliminated, patients have to remove the offending food for about 3 to 4 weeks if IgA antibodies are present or 3 to 6 months if the IgG antibodies are present as well. This is the only way for the antibodies to disappear, and the intestinal permeability can heal. But the disappearance of antibodies does not guarantee that oral tolerance has been established. If you are retesting a patient and if the antibodies are gone, that indicates that the patient has done an excellent job in eliminating that food from their diet. However, the only way to know is to reintroduce the food and retest after a few months, just to make sure that no antibodies are being produced after the intestinal barrier has been fully healed.

Conclusion

All in all, that is what the intestinal permeability does when we have IgA and IgG antibodies and what do they do when there is food sensitivity in the body.� However, it is crucial that our patients understand that we here at Injury Medical Clinic, take the time to study what causes inflammation in our patients and using integrated functional medicine to make sure that their intestines are being healed naturally. In the next article, we will discuss the difference between peptides and proteins, and about the Lectin and Dairy Zoomer.

 

The Microbiome Functions and Functional Medicine Part: 3 El Paso, Texas

The Microbiome Functions and Functional Medicine Part: 3 El Paso, Texas

In the last article, we talked about what the polyphenols do in the microbiome and in the previous section, we discussed about the microbiome functions in our bodies. However, today we will be concluding the three-part series of the microbiome functions in our bodies as well as presenting on the top 5 environmental toxins that can disrupt the gut microbiome, finding ways to de-stress ourselves, and learning about the different foods that can help detoxify our bodies so we can live a healthier life.

Top 5 Environmental Toxins Disrupting the Gut Microbiome

Triclosan

This is a synthetic antibacterial chemical found in personal care products such as soap, mouthwash, toothpaste, hand sanitizer, and deodorant. It is easily absorbed through the skin and gastrointestinal tract and rapidly alters the microbial composition of the digestive tract if it is ingested. However, this rapid restructuring of the gut microbiome impairs the immune system-regulating activities of gut microbes.

Triclosan

We use this chemical mostly in our daily skincare and hygiene routine so that way we won�t be sick. We tend to use this chemical compound to make us smell, look, and feel good frequently, especially in the cold and flu seasons where we use them the most so we won�t get sick. In fact, the frequent use of antibacterial products has been associated with an increased risk of food sensitivities, seasonal allergies, and asthma.

Pesticides

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Surprisingly there are a staggering 1 billion pounds of pesticides used per year in the United States, and 5.6 billion pounds are used worldwide. Most farmers used it to spray down the insects so that way their crops won�t be destroyed. And we used pesticides on our lawns to get rid of weeds and keep the bugs off our gardens.

However, did you know that pesticides can kill beneficial bacteria in our gut? Studies, especially animal studies, indicate that pesticides can destroy the beneficial gut bacteria and can increase the risk of intestinal dysbiosis and cause immune system disorders, among with many other chronic health issues.

Plasticizers

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These are chemicals that provide flexibility or rigidity to plastic products. These chemicals are highly prevalent in our environment and have a significant impact on gut bacteria. �Surprisingly the most common plastics are mostly BPA (Bisphenol-A).

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Bisphenol-A (BPA) can be found in plastic water bottles, receipts, and the lining of canned foods. They can alter the healthy gut flora and disrupts the body�s hormonal system by mimicking the hormone estrogen. We do use these to put our leftovers in after we consume food. But now and days when we meal prep our food, we do look for containers that are BPA- free. However, while often being marketed as �BPA-free,� the plastic alternatives may be equally, if not more, harmful to our gut microbes.

Bisphenol-S and bisphenol-F demonstrate endocrine-disrupting effects that are comparable to BPA. These adverse effects may extend to the gut microbiome, causing disruption. Phthalates are another class of endocrine-disrupting plasticizers that are used as solvents in personal care products and vinyl plastic, and they also reduce the levels of beneficial gut bacteria.

Heavy Metals

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Heavy metals, such as cadmium, lead, and arsenic, can reduce the levels of beneficial bacteria in the gut that protect against intestinal inflammation and may promote inflammatory gastrointestinal disorders. All microbes are responsible for methylating or demethylating metals, and the exposure may exceed the capacity to perform this. Due to industrial pollution, heavy metals are the most common contaminants that are in the soil and drinking water when we grow food and drink from the tap.

Pharmaceutical Drugs

Prescription Medications

Surprisingly most pharmaceutical drugs can help our bodies fight off infections or alleviate some pains we may be inflicted. But those antibiotics can disrupt the gut microbiome and cause an imbalance to our gut bacteria. We here at Injury Medical clinic, actually recommend our patients to alternatives to these drugs if you don�t want to disrupt your gut microbiome.

Functional medicines like whole foods and supplements can actually alleviate the pains that may cause disruption in your body.

Protecting the Microbiome From Environmental Toxins

When you want to live a healthier life and want to protect your body�s microbiome try these alternatives to get rid of these environmental toxins.

  1. Instead of using conventional cleaning products, which often contain triclosan, try switching to a plant-based brand. Also, try making your own cleaning products at home with natural ingredients.
  2. Avoid commercial body care products, as these are a significant source of triclosan, phthalates, and parabens. If you have any absorption of these chemicals, try checking out the Environmental Working Group�s Skin Deep Cosmetics Database. This database can help you find natural, healthy body care products that don�t contain microbiome-disrupting chemicals.
  3. Eat organic produce. Conventionally-grown fruits and vegetables are a significant source of microbiome-disrupting pesticide exposure. Research indicates that consuming organic food can significantly lower your body burden of pesticides, thus protecting your gut microbes. But y9ou are going to eat organic produce, remember to wash it first to get rid of excess pesticides.
  4. Try reducing your plastic intakes and limit your consumption of canned foods to reduce your exposure to BPA and BPA alternatives. When you are meal prepping, try using glass or stainless-steel water bottles and storage dishes instead of plastic, and opt for fresh food instead of canned.
  5. Try filtering your drinking and bathing water. Unfortunately, tap water is rife with pesticide residues, heavy metals, plasticizers, and pharmaceutical drug residues and can come off as a milky white if it�s not treated. So try to consider investing in a high-quality water filter that can remove these substances from your drinking water.
  6. Support your gut microbiome by consuming prebiotics and probiotics. In a previous article, we talked about probiotics in our gut. Probiotics can add beneficial bacteria to your stomach and may even help in the metabolism of toxins that are in your body�s microbiome. Prebiotics, a form of indigestible dietary fiber, that feeds probiotics and helps to support their growth and proliferation in the gastrointestinal tract.

Other Forms of Whole Body Detoxification

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There are many ways to try and detoxify our bodies, so here are some examples:

  • Sauna therapy
  • Yoga, trampoline
  • Meditation
  • Energy healing/shamanism
  • Taking a much-needed vacation
  • Learn communication methods to accommodate multiple needs and to deal with stressful situations

Rebuilding the Gut Microbiome

When local health coaches, practitioners, and chiropractors are helping patients, they can provide a comprehensive strategy to help them gain a healthier life. When you want to rebuild your gut microbiome, try to reconstruct the natural digestive function with food/herbals. This will help support the immune system and nutritional status by creating the good bacteria in your liver and flushing out the toxins out of your system. However, try to avoid any foods that can trigger inflammation and can cause leaky gut.

Rebuild Natural Digestive Function

When you are rebuilding your natural digestive function, try finding food and supplements that contain zinc, Vitamin C, and bitter greens that can aid in the production of hydrochloric acid (HCL). However, avoid excessive amounts of fat in your diet so you won�t cause a leaky gut Also take some enzymes if you need them until your digestive is balanced and fully restored.

Support the Immune System and Nutritional Status

When your immune system is being overworked, try using micronutrient testing to identify deficiencies. Most SIBO patients are typically low in B12/iron, zinc, magnesium, and vitamin D.� But all these vitamins and supplements can support the immune system. With SIBO patients, they try to work on cleaning out their liver since it�s one of the major organs that flushes out the toxins in our bodies. If you do have SIBO, try adding more fruits and plant foods that can help �clean out the liver.� Certain fruits can be tolerated and titrated up after treatment over time, but try to reduce meat/animal fats and fats in general; since they are harder to digest and can contribute to imbalanced bile acid secretion. Also, use liver support herbs and supplements such as glutathione and silymarin.

Avoid Foods that Can Provoke Inflammation

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In a previous article, we talked about food sensitivity and what to do if you have it. Some testing can be helpful to determine if other foods may need to be eliminated. Here are the most common foods that provoke inflammation in dysbiosis are:

  • Gluten
  • Dairy
  • Eggs
  • Soy
  • Corn

So if you have a food sensitivity, start by slowly build the natural SCFA�s with small amounts of natural resistant starch (e.g., cooked/cooled potatoes). However, if the patient is being treated with SIBO, introduce it after. Also considering adding other sources of food so it can help grow the good bacteria in your gut. But also keep HCL production active to clean out the stomach and upper part of the small intestine.

This will ensure that the good bacteria will grow over time with your diet and the help of probiotics and fermented food. But if a patient has SIBO take caution so the patient won�t disrupt the treatments they are in and are completed.

If you are taking care of a patient, carefully choose probiotic based on symptoms they have. Some will need a d-lactate free formula, and you can bring up the dosage over time until their treatment is complete. Some CFUs (colony forming units) will vary by product and viability through the GI tract (enteric-coated vs. not), and some probiotics may need to be used long term in some individuals.

Fermentation

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Fermented foods are very beneficial to our gut flora as they actually help in the production of good bacteria in our intestinal barriers. Fermented foods and beverages are literally alive with strong pronounced flavor and nutrition. However, not all preserved foods are fermented with live cultures; some may be brined through the use of vinegar and/or salt, and do not impart probiotic benefit.

 

El Paso Back Clinic�Fermentation is the transformation of food by various bacteria, fungi, and the enzymes they produce. It is important to recognize that fermentation is a natural phenomenon much broader than social, culinary practices; cells in our bodies are capable of fermentation. In other words, humans did not invent fermentation; it would be more accurate to state that fermentation created us.� � Dr. Alex JimenezD.C., C.C.S.T.

Conclusion

So all in all, those are some of the many ways to actually help our bodies microbiome when we want to live a healthier life. Here at Injury Medical Clinic, local chiropractors and health coaches, actually use functional medicine to patients so that way, they can fix their ailments naturally, without the use of drugs and non-conventional methods. If we can change a person�s lifestyle with functional medicine, we can repair the microbes in our bodies, one at a time naturally, of course.